KEGG   Tachyglossus aculeatus (Australian echidna): 119947579
Entry
119947579         CDS       T10703                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04010  MAPK signaling pathway
tacu04020  Calcium signaling pathway
tacu04022  cGMP-PKG signaling pathway
tacu04114  Oocyte meiosis
tacu04218  Cellular senescence
tacu04310  Wnt signaling pathway
tacu04360  Axon guidance
tacu04370  VEGF signaling pathway
tacu04380  Osteoclast differentiation
tacu04625  C-type lectin receptor signaling pathway
tacu04650  Natural killer cell mediated cytotoxicity
tacu04658  Th1 and Th2 cell differentiation
tacu04659  Th17 cell differentiation
tacu04660  T cell receptor signaling pathway
tacu04662  B cell receptor signaling pathway
tacu04720  Long-term potentiation
tacu04724  Glutamatergic synapse
tacu04728  Dopaminergic synapse
tacu04921  Oxytocin signaling pathway
tacu04922  Glucagon signaling pathway
tacu04924  Renin secretion
tacu05010  Alzheimer disease
tacu05014  Amyotrophic lateral sclerosis
tacu05020  Prion disease
tacu05022  Pathways of neurodegeneration - multiple diseases
tacu05031  Amphetamine addiction
tacu05152  Tuberculosis
tacu05163  Human cytomegalovirus infection
tacu05166  Human T-cell leukemia virus 1 infection
tacu05167  Kaposi sarcoma-associated herpesvirus infection
tacu05170  Human immunodeficiency virus 1 infection
tacu05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tacu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119947579 (PPP3CA)
   04310 Wnt signaling pathway
    119947579 (PPP3CA)
   04370 VEGF signaling pathway
    119947579 (PPP3CA)
   04020 Calcium signaling pathway
    119947579 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    119947579 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    119947579 (PPP3CA)
   04218 Cellular senescence
    119947579 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    119947579 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    119947579 (PPP3CA)
   04660 T cell receptor signaling pathway
    119947579 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    119947579 (PPP3CA)
   04659 Th17 cell differentiation
    119947579 (PPP3CA)
   04662 B cell receptor signaling pathway
    119947579 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    119947579 (PPP3CA)
   04921 Oxytocin signaling pathway
    119947579 (PPP3CA)
   04924 Renin secretion
    119947579 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    119947579 (PPP3CA)
   04728 Dopaminergic synapse
    119947579 (PPP3CA)
   04720 Long-term potentiation
    119947579 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    119947579 (PPP3CA)
   04380 Osteoclast differentiation
    119947579 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119947579 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119947579 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    119947579 (PPP3CA)
   05163 Human cytomegalovirus infection
    119947579 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119947579 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    119947579 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119947579 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    119947579 (PPP3CA)
   05020 Prion disease
    119947579 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    119947579 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    119947579 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119947579 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tacu01009]
    119947579 (PPP3CA)
Enzymes [BR:tacu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     119947579 (PPP3CA)
Protein phosphatases and associated proteins [BR:tacu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     119947579 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 119947579
NCBI-ProteinID: XP_038625056
LinkDB
Position
X5:complement(12265402..12684219)
AA seq 521 aa
MSEHKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDVLKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKAISSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcacaaggcaattgatccgaagttatcgacgacggaccgggtggtgaaagct
gtcccgtttcccccaagtcatcggctcacagcgaaggaagtgtttgacaacgatgggaag
cctcgggtggatgtcttaaaagcccacctcatgaaagaggggaggctggaagagagcgtg
gctctgagaattataacggagggcgcgtcgattctgcgacaggaaaagaatcttctggac
atagacgctccggtcacagtttgcggagacatccacggacagtttttcgacttaatgaag
ctatttgaagtgggcgggtccccggctaatactcgctacctgttcctgggggactacgtg
gacagaggctacttcagcatcgagtgtgtgctatatttgtgggccttgaaaatcctttac
cctaaaacactgtttttacttcgtgggaaccatgaatgtagacatttaacagaatatttc
acgtttaaacaggaatgtaaaataaagtactcagaacgtgtgtacgacgcgtgcatggac
gcctttgactgcctgcccttggctgccctgatgaaccaacagttcctctgcgtgcacggt
ggcttgtccccagaaatcaacaccttagatgatatccgaaaattagatcgattcaaagag
ccacctgcttacggacctatgtgtgacatcctgtggtcagaccccctggaggactttgga
aatgagaagactcaagagcatttcactcataacaccgtcaggggatgttcgtacttctac
agctaccctgctgtatgcgaattcttacagcacaataacttgttatctatactccgagcc
catgaagcccaagatgcagggtatcgcatgtacaggaaaagccagacgacaggcttccct
tctctaattacaattttttcagcaccaaactatctagacgtgtacaataacaaagctgca
gtattgaaatatgagaacaatgttatgaacatcagacagttcaactgctctcctcatcca
tactggcttccaaatttcatggatgttttcacttggtctctaccctttgtgggggaaaaa
gtgacagagatgctggtcaacgtcctgaacatctgctcagatgacgaactagggtcggaa
gaagatggatttgatggagcaacagctgcagcccggaaggaagttataaggaacaagatc
cgagcaatagggaaaatggctcgagttttctctgtactgagagaagagagtgagagcgtg
ctgaccctgaaaggcttgaccccaaccggaatgctgcctagtggagtactctccggagga
aagcaaactctacagagcgctactgttgaggcaattgaggctgatgaagccatcaaagga
ttttcaccacagcataagatcactagcttcgaagaagccaagggcttagaccgaattaac
gagagaatgcctccccgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctatctcctcagagacaaatggcacagacagcaatggcagcaacagcagcaatatt
cagtga

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