KEGG   Tachyglossus aculeatus (Australian echidna): 119948891
Entry
119948891         CDS       T10703                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
tacu  Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04010  MAPK signaling pathway
tacu04060  Cytokine-cytokine receptor interaction
tacu04068  FoxO signaling pathway
tacu04144  Endocytosis
tacu04218  Cellular senescence
tacu04350  TGF-beta signaling pathway
tacu04371  Apelin signaling pathway
tacu04380  Osteoclast differentiation
tacu04390  Hippo signaling pathway
tacu04520  Adherens junction
tacu04659  Th17 cell differentiation
tacu04926  Relaxin signaling pathway
tacu04933  AGE-RAGE signaling pathway in diabetic complications
tacu05142  Chagas disease
tacu05161  Hepatitis B
tacu05166  Human T-cell leukemia virus 1 infection
tacu05200  Pathways in cancer
tacu05210  Colorectal cancer
tacu05212  Pancreatic cancer
tacu05220  Chronic myeloid leukemia
tacu05225  Hepatocellular carcinoma
tacu05226  Gastric cancer
tacu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tacu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119948891 (TGFBR1)
   04350 TGF-beta signaling pathway
    119948891 (TGFBR1)
   04390 Hippo signaling pathway
    119948891 (TGFBR1)
   04371 Apelin signaling pathway
    119948891 (TGFBR1)
   04068 FoxO signaling pathway
    119948891 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    119948891 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    119948891 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    119948891 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    119948891 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    119948891 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    119948891 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119948891 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119948891 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119948891 (TGFBR1)
   05212 Pancreatic cancer
    119948891 (TGFBR1)
   05225 Hepatocellular carcinoma
    119948891 (TGFBR1)
   05226 Gastric cancer
    119948891 (TGFBR1)
   05220 Chronic myeloid leukemia
    119948891 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119948891 (TGFBR1)
   05161 Hepatitis B
    119948891 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    119948891 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    119948891 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    119948891 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tacu01001]
    119948891 (TGFBR1)
Enzymes [BR:tacu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     119948891 (TGFBR1)
Protein kinases [BR:tacu01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   119948891 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase
Other DBs
NCBI-GeneID: 119948891
NCBI-ProteinID: XP_038626349
LinkDB
Position
X3:33306194..33337795
AA seq 499 aa
MERAAPSAAYRMCLLMAALATGAEALQCFCHLCTKDNFTCVTDGLCFASITETADKVIHN
SMCIAEKDLIPRDRPFVCAPSAKDGIVTKPYCCDTDHCNKIELPTTGPPREKLSPSLGPV
ELAAVIAGPVCFVCISLMLILYICHNRPAIHIRVPNEEDPSLDRPFISEGTTLKDLIYDM
TTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFR
EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIK
LALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDT
IDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSVGGIHEDY
QLPYHDLVPSDPSVEEMRKIVCEQKLRPNIPNRWQSGEALRVMAKIMRECWYANGAARLT
ALRIKKTLSQLSQQEGIKM
NT seq 1500 nt   +upstreamnt  +downstreamnt
atggagcgggcggccccctcagccgcctaccggatgtgcctcctcatggcggccctggcg
acgggggcggaggcattacagtgtttctgccacctctgtacaaaagacaactttacgtgt
gtaacagacggactctgcttcgcctcaataaccgagacggcagacaaagttattcacaat
agcatgtgcatcgcagaaaaggatctgattccccgagacaggccgtttgtgtgtgcaccc
tccgctaaggatgggatagtgaccaaaccgtattgctgtgacacagatcactgcaacaag
atagagctgcccaccacaggccctcctcgcgagaagctgtctcctagcttaggtccggtg
gagttggccgccgtcatcgccggacccgtctgcttcgtctgcatttccctcatgctcatc
ttgtacatctgtcacaatcggcccgccatccacatccgggttccaaacgaagaagacccc
tccttagatcgccctttcatctccgagggcaccacgttgaaagacttaatttacgacatg
accacgtcgggatcggggtcaggtttacccttactcgttcaaaggacaattgcaaggacc
atcgtgttgcaagaaagcatagggaaaggtcgcttcggagaagtctggcgaggaaaatgg
cgaggagaagaagttgctgtgaaaatattttcctcgagagaagaacggtcctggttccgc
gaggcagagatttatcagacggtgatgttgcgtcatgaaaacattctgggattcatcgca
gctgacaataaagacaatggtacgtggactcagctctggttggtgtctgattatcatgaa
catggatccctttttgattatttaaacagatataccgtcaccgtggaaggaatgatcaag
ttagctctgtccaccgccagtggactggcacatcttcacatggagattgtcggtacccaa
ggaaagccagctattgcccacagagatttgaaatccaaaaacatcttagtcaagaagaac
gggacatgctgcattgccgacttgggattggcagtaagacacgattcagccacagataca
atcgatattgccccgaaccaccgagtgggaactaaaaggtacatggcccctgaagttcta
gatgattccataaatatgaaacactttgaatcattcaaacgagctgacatctatgcaatg
ggattagtgttctgggaaatagctcggcgctgttcagttggtggaattcatgaagactac
cagttgccctaccatgacctggtaccttcggatccctcggttgaagagatgcggaagatc
gtttgcgaacagaagcttcggcccaatatccccaaccggtggcagagcggcgaagccttg
cgcgtgatggccaaaattatgcgggagtgttggtacgccaatggggccgcgaggctcaca
gctttacgcattaagaaaactttgtcacagctcagccagcaggagggcataaaaatgtaa

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