Tachyglossus aculeatus (Australian echidna): 119949258
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Entry
119949258 CDS
T10703
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu04217
Necroptosis
tacu04380
Osteoclast differentiation
tacu04620
Toll-like receptor signaling pathway
tacu04621
NOD-like receptor signaling pathway
tacu04630
JAK-STAT signaling pathway
tacu04658
Th1 and Th2 cell differentiation
tacu04659
Th17 cell differentiation
tacu05145
Toxoplasmosis
tacu05160
Hepatitis C
tacu05161
Hepatitis B
tacu05162
Measles
tacu05164
Influenza A
tacu05165
Human papillomavirus infection
tacu05167
Kaposi sarcoma-associated herpesvirus infection
tacu05168
Herpes simplex virus 1 infection
tacu05169
Epstein-Barr virus infection
tacu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
119949258 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
119949258 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
119949258 (TYK2)
04621 NOD-like receptor signaling pathway
119949258 (TYK2)
04658 Th1 and Th2 cell differentiation
119949258 (TYK2)
04659 Th17 cell differentiation
119949258 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
119949258 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
119949258 (TYK2)
05160 Hepatitis C
119949258 (TYK2)
05171 Coronavirus disease - COVID-19
119949258 (TYK2)
05164 Influenza A
119949258 (TYK2)
05162 Measles
119949258 (TYK2)
05168 Herpes simplex virus 1 infection
119949258 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
119949258 (TYK2)
05169 Epstein-Barr virus infection
119949258 (TYK2)
05165 Human papillomavirus infection
119949258 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
119949258 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tacu01001
]
119949258 (TYK2)
Enzymes [BR:
tacu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119949258 (TYK2)
Protein kinases [BR:
tacu01001
]
Non-receptor tyrosine kinases
JAK family [OT]
119949258 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
SH2_1
Kdo
Kinase-like
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
119949258
NCBI-ProteinID:
XP_038626799
LinkDB
All DBs
Position
X2:complement(9035284..9047011)
Genome browser
AA seq
1210 aa
AA seq
DB search
MPLCRRSLRSSELDVDKAQGSVTGGLKVFLYWSDGGEGHVTFDLGTLTAEEICIQIAQKI
GITPICHSLFALYDPQIRTWFPPSHVFEVARDSSWSLHFRMRFYFRNWHGLHTQELAVYR
HGPRAPGGPRGRAEQGEALLDQASFEYLFEQGKFDFVNDVVSLWEQPSEAEIRRFKNESL
GMAVLHLAHLALRRGVPIWDVAKTTSLKDCIPRSFYWHLQRHSSLTRFRMHNVFRKFLRH
FQTETARPGQLGPQDVMVKYLATLEQLAPRFGTERFPALELALPVGPRLEPEPGCVPSSH
PLLAPDTHSGPPAPGDPTATHEVLVTGTGGVAWRPLPAQDPVLGPERGPFPGGGSRLRRP
RHRARKVESRETGAGKEAPWERFCDFQEITHVVLTGSRVTIHRRDNQSLELALPTPAAAL
SLISLVDGYFRLTTDASHYLCRQVAPPQLMMSIMNGIHGPLGEAYVRAKLQREEPEDGLY
LIHWSARHFHKMILAVSRWDRARAPTPTPTAALSELTYRQFCIWQHQGPTFQLEGWERGF
STIGELTAALRGCSLRSGPDSFTVRRCCPPRPGEISNLIITRRPQDSPKPHSLTQLSFHQ
IHKDEITQLAHLGQGTRTQLYEGRLRVGAAGSPSEPNNNQQELRVVLKVLDPSHRNISLA
FFETASLMNQVSHIHVAFVYGVCVRGSENIMVEEFVEAGPLDVCLRREKGRLPVAWKVTV
AQQLASALSYLEDKNLMHGNVCAKNVLLARRGLEDGLQPFIKLSDPGVSFAVLSREERVE
RIPWIAPECVQSGTGCGPAADKWSFGTTLLEICFDADAPLRERTPSEKERFYEKQHPLPE
PSCRELATLIGQCLTYDPSQRPSFRTVLRDLTQLQPQNLLGIIAVRPGAPAVDPSLFQKR
YLKKVRDLGEGHFGQVSLCCYDPVGDGTGEMVAVKSLKADCGSRLRGSWEREIRILRALY
HQNIVKYKGCCSDQGEKVLQLVMEYMPLGSLRDYLPKHSVGLAQILLFAQQICEGMSYLH
SQHYVHRDLAARNVLLENGSVVKIGDFGLAKAVPDGQDYYRVREDGDSPVFWYAVECLKE
CKFYYSSDIWSFGVTLYELLTHCDPGQSPPMKLVELIGTTQGQMTVLRLIDLLDRGQRLP
CPKDCPWEIYLFMKNCWEPDPSFRPTFKNLIPVLGAFREKYRGQAPSIFSRPASPSCPGL
GPPPVPRPGG
NT seq
3633 nt
NT seq
+upstream
nt +downstream
nt
atgcccttgtgccgccgctccctgcggtctagcgagttggacgtggacaaggcccagggc
tcagtgaccggaggcctgaaggtcttcctgtactggagtgatggtggggagggccacgtg
acgttcgacctgggcaccctgactgccgaggagatctgcatccagattgcccagaagatc
ggcatcacccccatctgccacagcctctttgccctgtatgacccacagatccggacctgg
tttcctcccagccatgtctttgaggtcgcccgggatagcagttggagcttgcacttccgc
atgagattttacttccgtaactggcatgggctgcacacccaggagctggccgtgtaccgc
cacgggccccgggcccctgggggccccagggggcgggcagagcagggagaggcgctgctg
gaccaagcgtcgttcgagtatctcttcgagcagggcaagtttgactttgtgaacgacgtc
gtgtccctgtgggagcaacccagtgaggctgaaatccgccgtttcaagaacgagagtctg
ggcatggccgttctgcacctcgctcacctggccctgcggcgaggcgtccccatctgggac
gtggccaagaccaccagcttgaaggactgcatcccgcgctccttttactggcacttgcag
cggcacagctctctaacccgcttccgcatgcacaacgtcttccgcaagttcctgcggcat
ttccagacggagacggcccggcccgggcagctgggcccccaggacgtcatggtcaagtac
ctggccactctggagcagctggcgccccgcttcggcaccgagcgcttcccggccctggaa
ctggcgctgccggtcgggccgaggttggagccggaaccgggctgcgtccccagcagccac
cctctgctcgcgcctgacacccactctggcccgccagcccccggggacccaacggccacc
catgaggtgctggtgacaggcaccgggggtgttgcgtggcggccgctgccggcccaggac
ccggttctgggcccggagaggggccccttccctggtggcggctcccgcctcagaaggccg
aggcaccgagcccggaaggttgagagccgggagacaggtgcgggaaaagaggcgccgtgg
gaacgcttctgtgacttccaggagatcacgcacgttgtcctcacgggcagccgcgtcacc
atccaccggcgggacaatcagagcctggagctggccctccctaccccggcagccgccctc
tccctgatctctctggtagacggctactttcggctaaccacagatgccagccactacttg
tgccgtcaggtagctcccccccagttgatgatgagcatcatgaatggcatccacgggcca
ctcggagaggcatacgtccgggccaagctgcagagagaagaaccagaagatgggctgtac
ctgatccactggagcgcccgtcatttccacaagatgatcctggctgtgtccaggtgggat
cgggccagggccccgacccccactcccaccgccgccctctccgagctgacctacaggcag
ttctgcatctggcagcaccagggccccacgttccagctggagggttgggaacgcggcttc
tccaccatcggcgagctcacggccgctctccggggctgcagcctgcgctctggccccgac
agcttcaccgtccgccgctgctgcccaccccggccgggagagatttccaacctgatcatt
acccggcgacctcaggacagccccaaaccacacagcctcacccagctcagcttccaccag
atccacaaggacgagatcacccagctggcccacttgggccagggcacccggacacagctg
tacgagggccgccttcgcgtgggggccgcggggagcccctcggagccaaacaacaaccag
caggagctgcgcgtggtgctcaaggtgctggaccccagccaccggaacatctctttggca
ttcttcgagacagccagcctgatgaaccaggtctcccacatccacgtggctttcgtctac
ggcgtctgtgtgcgaggctctgagaacatcatggtggaggagtttgtggaggccggcccg
ttggatgtctgcctccgccgggagaagggccgcctgcctgtggcctggaaggtcaccgtg
gcccaacagctggccagtgccctcagctacttggaggacaagaacctgatgcacgggaac
gtctgcgctaagaatgtcctgctggcgcggcggggcctggaagacggcctgcagcctttc
atcaagctcagtgaccctggagtcagctttgctgtgctctcccgggaagagcgagtggag
aggatcccctggatcgcgcccgagtgcgtgcagagcgggacaggttgcggcccggccgcg
gacaagtggagctttggcacgacgctcctggagatctgcttcgatgctgacgctccgctc
cgggaacgcactccctctgagaaggagcgtttctatgagaagcagcacccgctccccgag
ccatcatgccgagaacttgccaccctgattggccagtgcctgacctacgaccccagccag
cggccctccttccgcaccgtactgcgtgacctcacccagctgcaacctcaaaacctgctc
ggcatcatcgcggtcaggcccggtgcccccgccgtggacccctcgctgttccagaagcgc
tacctgaagaaggtccgagacctgggagagggccactttggccaagtgagcttgtgctgc
tacgaccccgtgggcgacggcaccggcgagatggtggccgtcaagtctctcaaggccgac
tgtggctcgcggctccggggaagctgggagcgggagatccggatcctgcgggcgctctat
caccaaaatattgtcaagtacaagggctgctgcagtgatcaaggggagaaggtgttgcag
ctggtcatggagtacatgccgctgggcagcttgcgggactatctacccaaacatagcgtg
ggtctggcccagatcctgctctttgcccagcagatctgtgagggcatgtcctacctccac
tcccagcactacgtccatcgggacctggcggcccgcaacgtgctgctggagaatggcagt
gtggtcaagatcggggactttggcctggccaaggccgtgcctgacgggcaggactactac
cgtgtgcgcgaggatggggacagtcctgtgttctggtacgctgtggagtgcctcaaggag
tgcaagttctactacagctccgacatctggtcctttggggtcaccctctatgagctcctg
acccactgcgaccccggccagagtcccccgatgaaattagtggagctcatcgggaccacc
cagggccagatgactgtgctgaggctcattgacctgctggaccgaggccagaggttgccc
tgccctaaggactgtccctgggagatctatctcttcatgaagaactgctgggagcccgac
ccatccttccgcccgaccttcaagaacctcatccccgttctcggggccttccgggagaag
taccggggccaggccccctccatcttcagcaggcctgcttccccttcctgtccaggactc
ggtccccctccagtcccacgtcccggaggatag
DBGET
integrated database retrieval system
