Tachyglossus aculeatus (Australian echidna): 119950102
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Entry
119950102 CDS
T10703
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
tacu Tachyglossus aculeatus (Australian echidna)
Pathway
tacu00310
Lysine degradation
tacu01100
Metabolic pathways
tacu05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
tacu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
119950102 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
119950102 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tacu03036
]
119950102 (DOT1L)
Enzymes [BR:
tacu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
119950102 (DOT1L)
Chromosome and associated proteins [BR:
tacu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
119950102 (DOT1L)
HMT complexes
Dot1-containing complex
119950102 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
119950102
NCBI-ProteinID:
XP_038628019
LinkDB
All DBs
Position
X1:complement(135498402..135607049)
Genome browser
AA seq
1787 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVQ
ENKVAVLLDCHMDSGAEEDKTGAATMKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNTA
NTERKPKKNQTALELLHAQTVSQTASSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPT
PPALQKLLDSFKIQYMQFMAYMKTPQYKANLQQLLEQEKEKNAQLLGTAQQLFIHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKENSELRNQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELLQLK
SYMPADETPSVHLRHKSHLNRELEPDPSRFQLELECAKFSLPHINGMSPELSMNGHAAPY
EIPSALSRPSSKQNTPQYLTSHLDQEIVPCTPNHNSRQKADRVASLSIPDYTRFSPAKIA
LRRHLNQDHAATGKAPASDLHQRAEHAKENGLSYQSPGVSNGIKLSPQHVRPSSPSALQI
AAGEKNTEKVLKERAYASNGETITSLPISIPLSTVQPNKLPVSIPLSSVVLPSRVEKVRS
TPSPVHQTRDSTSTLEKQFGANSYNGLSSATGTKPFASATSGFSYSGSVAVGGTVSSSPA
QLNHVVEQTALDDPSNSGSLFNAVGSRSSTPQHPSLLMMQCRNSGPNSPAHQHPLSPRLP
GAAQGLPGAAQHADAQKMFTEGHMGDLQSDWGFSDPESEAKRRIIFTISTNAGNLKQSPS
NKHSPLTASIRTDCGPAYMQDGKKRGRRKRSSSGHPSGLSPKRKPLPSVAGLFTPSSGSP
LNINSMVNNINQPLEITAISSPENSLKNSPVPYQDNDQPPVLKKEKPLIQTNGIYYSPLT
SDEEQGYEDERNSTRIERKIATISLESKSPPKSVENAGGSSSSGRKPGPTHENTNSSKWK
STFSPISDLHLAKTADSPGQAAPPLFTFRPPSEDAGPADGKLSAHPRKSLAGGSAGAGAL
SPNGFAYNGGLSADLSLHSFPDGASLSHKASEVTGLHSPLGFPSQRSRDVSVSETNPFLN
KRQLDGLGGLKGDEFGRAGGKSKEMSELGAHSSEKGPLQHSGKVGKGRDRDLEFKNGHNL
FIAAAAAAAPPGGLLNGRSLPTAGPSSGNSVSAVQTHHPFLNAVTAGSQFPLGPGALPAN
LSSVASSSVLQSLFNSVPAAASLVHVSSAATRLTNSHAMGSFSSGVTGGTVGGIFNHAVP
SASSHQFGASFSSSTACSSAVLSSNPLQAVASTATSSFQAPSTASSASSAAAASSSSSSS
PPSSSSSVTPSATRAVQHLHRPSGPPGLRAPPPPPPNLLSLPPPPPLLASTSEPALLPSF
PSVPANDTFIASSSSSSSSSSSFSSSSSSSSASAAAASVQSASASLSIKLASLPHKASHP
SFTVHHQPLPRLAPMIAQSSAPGSSAMWVTLGTQSPYASHLSGVKPR
NT seq
5364 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggaactgaggctgaagtcgcccgtgggagcggagcctgccgtgtac
ccctggcccttgccggtctacgataaacaccacgatgctgctcatgaaatcattgagacc
attcgatgggtctgtgaagaaatcccagatctgaaacttgccatggaaaattatgttttg
attgactatgataccaaaagctttgaaagcatgcagagactctgtgacaagtacaaccga
gccattgatagcatccatcagttgtggaaaggaaccacccagcccatgaaactgaacact
cgtccatccaatggacttctccggcatattttgcagcaagtgtataaccactcagtgacg
gacccagagaaactcaacaactatgagcctttttccccagaagtgtatggagagacttcg
tttgacttagtggcccagatgattgatgagattaaaatgacagaagatgatttgtttgtg
gacttgggcagtggagtgggtcaggtggtgcttcaggtggcggcagccaccaactgcaag
catcactatggtgtggagaaagctgatattccagccaagtatgccgagacaatggacaga
gagttcagaaaatggatgaaatggtatgggaaaaagcatgcagaatacacactggaaaga
ggtgacttcctttcggaagagtggcgagaacgaatagcaaatacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccaactgaaagaacgatttgcaaacatg
aaggaaggtggcagaatcgtatcctcaaaaccttttgcacctctaaactttagaataaac
agtaggaacttgagtgatattggcactataatgagagttgtggagttatcaccactgaaa
gggtcggtttcatggactgggaaaccagtctcttactacttgcataccattgatcgaaca
atacttgaaaactatttttctagtctcaaaaatccaaagctcagggaggaacaagaggca
gctagacgccgacagcaaagagaaaacaagagtaatacgacaactccaacaaaggtccaa
gaaaacaaggtagctgtcctcttggattgtcacatggattctggtgctgaagaagataaa
actggggcagcaactatgaaaaagccatctccctccaaagcacgcaagaaaaagttaagc
aagaaaggaaggaagatggcgggcagaaagcgtgggcgccccaagaaaatgaacactgca
aacactgagcgcaagcccaagaagaaccaaactgcactggagctcctacatgctcaaact
gtgtcccagacagcatcatcctctcctcaggatgcatacaagtcacctcatagtccatat
taccaactacctcctaaagtgcaacggcattcatctaatcagctgttggtgactcccacc
ccccctgcactacagaagctgctagactcctttaagattcagtacatgcaattcatggca
tacatgaaaactcctcaatataaggcgaacctacagcagttactcgagcaagaaaaggaa
aaaaatgcccagctgctgggcactgcacaacaactgttcatccattgccaggcccagaaa
gaggaaatcaaacgactgtttcagcagaaactcgatgagttgggagttaaggcactgact
tacaatgacctgattcaagctcagaaagagatctccgctcataaccagcagctaaaggaa
caaaccaaacagctagagaaagagaacagtgaactcaggaaccagagcttacagctgctt
aaggctcgatgcgaagagctgaagctggattggtccaccctgtcgctggagaatttactg
aaggagaagcaggccctgaagaatcaaatttcagagaaacagaagcattgtttggagttg
cagatcagcatcgtggagctggagaagagtcaaaggcagcaggagctgttgcagctcaag
tcctacatgccggctgacgagacaccgtcggttcacttgcgccacaaaagccatttaaac
cgggagctcgaacccgatcccagccgattccagcttgagctcgagtgcgccaagttctct
ctgccccacatcaatggcatgagccccgaactgtccatgaacggccatgcggctccctac
gaaattcccagcgcgctgagccgaccctcttccaagcagaacacccctcagtacctgacc
tcccacctggaccaagaaatcgtgccctgcactcctaaccacaacagcaggcagaaggcg
gaccgagtggccagtttatccatccccgactacacccggttttccccggccaagatagcc
ctacggagacacttgaatcaggatcatgcagccactgggaaagccccagctagtgacctg
caccagagagctgagcacgccaaagagaatggcctttcatatcagagccccggggtttca
aacggcataaagctgagtcctcagcacgttcggccttcttctccttctgctttacagatt
gcagcgggagagaagaacactgagaaggttttgaaagaaagagcctatgccagcaatgga
gaaacgatcaccagcttacccatcagtattcctctcagcacagtgcaacccaataaactc
cctgttagtatcccactgtccagtgtagtcctgcccagccgggttgagaaggtgagaagc
acacctagtccagttcatcagactcgagactctacttcaacacttgaaaaacagtttggt
gctaattcctataatggtctaagcagtgctactggaaccaagccctttgcttcggctacc
tcaggtttttcttattctggctcggtggcagtcgggggaactgtttccagcagcccggcc
cagcttaaccacgtcgttgagcagactgctctggatgacccgtccaattcggggagtctg
ttcaacgcagtaggctcccggagctccaccccacaacatccttctttgctcatgatgcag
tgccggaattctggtccgaactcccccgcccaccagcacccgttgagcccccggctcccc
ggggccgcccaggggctgcctggggcggcccagcatgcagatgctcagaagatgttcact
gagggccacatgggagacctgcagtctgattggggcttttctgatcccgagagtgaagcc
aagagaagaattatctttaccatctctacaaatgcaggaaacctaaaacagtctccttcc
aacaagcacagtcccctaacggcaagcatccgaacggactgtgggccagcctatatgcag
gacggcaagaagagagggaggaggaagcggtcttccagcgggcaccccagcgggctgtct
cccaaacgcaaacccttaccatccgtggcgggactctttactccgtcgtcaggctcgccc
ctcaacatcaactctatggtcaataacattaatcagcctttagagatcacagccatttcc
tccccggaaaactccctgaagaattctcctgttccctaccaggacaacgaccaaccgccg
gtgctgaaaaaggagaagccgctcatccagaccaatgggatttactattccccgctcaca
tctgatgaagagcagggatatgaagatgagcgcaacagcaccagaatcgaaagaaaaatt
gccaccatctctttggaaagcaaatccccaccaaaatcagtggaaaatgcagggggcagc
agttcgtcaggaaggaagccgggaccgacccacgagaacacgaacagcagcaagtggaag
tccaccttctcgcccatctccgacctccacctggccaagacggccgacagccccgggcag
gccgcgccgcctctgttcaccttcaggccgccctcggaggacgccgggcctgccgacggc
aagctctcggcgcacccccggaaaagcttggccgggggctcagcgggggctggcgcactc
agcccgaatggatttgcctacaatgggggcctgtcagccgatctcagtttacacagcttt
cctgatggtgcttctctgtctcataaggctagtgaggtgacgggcttacattctcctctg
ggttttccgtcccagcggagcagagacgtcagtgtctccgagacaaacccctttctgaac
aagcggcagctggatggcctgggggggttgaaaggggatgagtttgggagggcagggggc
aaaagcaaagagatgagcgagttgggggcacattcgtcagaaaaaggccccctgcagcac
agtggcaaggtcgggaaaggacgggaccgcgacctggagtttaaaaatggccacaacctt
ttcatcgccgccgccgccgccgccgcccctcctgggggccttctcaatggcagaagcctt
cccacggctggcccctcttctggcaactcggtatctgccgtgcaaacgcaccatcctttc
ttaaacgctgtcaccgctggatcccagttccccctgggccccggggccctgccggccaac
ctcagctctgtggccagctcgtcggtcttgcagtccttatttaattcggtgcccgcagct
gccagtttggtccacgtgtcatcggctgcaaccagactgacaaattctcatgctatgggg
agcttctcttctggggtgacgggtggaacagttggaggtatttttaaccacgcggtgcct
tctgcctcttctcatcagtttggagccagtttcagcagcagcactgcctgtagcagcgca
gtgctaagctcaaacccgctgcaggctgttgccagcacggccacctcttcctttcaggcc
ccttctactgcttcttctgcttcttctgctgctgctgcttcttcttcatcttcttcttct
cctccttcttcttctagctccgtaacacccagtgccacccgagctgtccagcacctacac
cggccctctgggccacccggcctccgggccccgccacctcctcctcctaacctcctctcg
ttacctccccctccaccactgcttgcctctacctccgagcccgctcttctgcccagcttt
ccctcagttccagctaatgacacttttatagcctcctcgtcgtcgtcgtcctcctcctcc
tcctctttctcctcctcctcctcctcttcctccgcctctgctgccgctgcttctgtccag
tctgccagtgcgtctttgtctatcaagctagcttctcttccgcacaaagcctcccatccc
tctttcacagtccaccaccagcctctgccccgcttggcacccatgattgcgcagtccagt
gccccgggctcctctgcgatgtgggttaccctgggcacgcagtctccctatgcttcgcat
ctttctggggttaagccacgataa
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integrated database retrieval system
