Thauera aromatica: Tharo_0920
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Entry
Tharo_0920 CDS
T05381
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tak
Thauera aromatica
Pathway
tak00300
Lysine biosynthesis
tak00550
Peptidoglycan biosynthesis
tak01100
Metabolic pathways
tak01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tak00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tharo_0920
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tharo_0920
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tharo_0920
Enzymes [BR:
tak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tharo_0920
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AVR87862
UniProt:
A0A2R4BKS2
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Position
952734..954134
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AA seq
466 aa
AA seq
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MMTVHDAVRALAVHQAHAQGEARFECVGSDSRALVPGQLFVALRGERFDGHAFVAEAAAQ
GAAAALVDAEWAAGQALAPLPLIVVDDTRRALGTLAASWRARFALPLLGVTGSNGKTTVK
EMCAAILRAQARCDGFGDDSVLATRGNLNNDIGLPLTLLELRDFHRAAVIEMGMNHPGEI
AYLSALAQPTAAIVTNAQRAHLQGLGSVEEVAREKGAIYQGLGATGIAVINADDPHAGEW
RAVNAGRRIVTFGIERAADVRGQCTLRGLGSRLELDTPAGQFGFVLQVPGLHNARNAVGA
AAVCLAAGVSPEAVADGLAGFTGARGRLQRRSGPRGALILDDTYNANPDSVRAAIDVLAS
LPGHTWLVLGDMGEVGGISAQVHDEIGGYAKSKGVDGLFALGEMSAIAVRNFGEGGHHFA
SAEALVKALAPRLDADSVVLVKGSRFMSMERVADALVAMHNSAPST
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgatgaccgtgcacgatgcggtgcgggcgctcgccgtccatcaggcgcacgcgcaaggg
gaggcgcgcttcgaatgcgtcggcagcgatagccgggcgctggttcccggccagctgttc
gtcgccttgcgtggcgagcgcttcgacggtcacgccttcgtcgccgaagccgcggcgcag
ggcgcggcggcggcactggtcgacgccgagtgggccgccgggcaggcgctcgcgccgttg
ccgctgatcgtcgtcgacgacacccggcgcgcgctcggcaccctggcggcgagctggcgc
gcccgcttcgccttgccgctgctgggggtgactggcagcaacggcaagaccacggtcaag
gaaatgtgcgcggcgatcctgcgcgcccaggcccgctgcgacggtttcggcgacgacagc
gtcctcgccacccgcggcaatctgaacaacgacatcggcctgccgttgaccctgctcgaa
ctgcgcgacttccaccgcgcggcggtgatcgagatggggatgaaccatcccggtgaaatc
gcttacctgagcgcactcgcgcagccgaccgcggcgatcgtcaccaacgcccagcgcgcc
cacctgcagggcctcggctcggtcgaggaggtcgcccgcgagaagggggcgatctatcag
ggcctgggtgcgaccggcatcgccgtgatcaacgccgacgacccgcacgccggcgagtgg
cgcgcggtcaatgccgggcgccggattgtgacattcggtatcgagcgggcggcggacgtg
cgcgggcagtgtaccctgcgcggcctcggctcccgcctcgaactcgacacgcccgccggg
cagtttggtttcgtcctgcaggtgccgggtttgcacaatgcgcgcaacgccgtaggggcg
gcggcggtctgcctcgctgcgggcgtttcgcccgaagcggtggccgacgggctggcgggg
ttcaccggcgcgcgcggtcgtctgcaacggcgcagcggtccgcgcggcgccctgatcctg
gacgacacctacaacgccaacccggactcggtgcgtgctgccatcgacgtcctcgcctcg
cttcccggccatacctggctggtgctcggcgacatgggggaagtcggcgggatcagcgcc
caggtgcatgacgagatcggcggctacgccaagagcaagggcgtcgacggcctgttcgcg
ctgggcgagatgagtgcgattgcggtgcgcaatttcggcgagggcgggcatcacttcgcc
tcggccgaggcgctcgtcaaggcgctcgctccgcgcctcgacgcggattcggtggtgctg
gtgaaaggctcgaggttcatgagcatggaaagagtggcggatgcgcttgtggcaatgcac
aattccgccccttcaacgtaa
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