Thauera aromatica: Tharo_2461
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Entry
Tharo_2461 CDS
T05381
Name
(GenBank) Mur ligase middle domain protein
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tak
Thauera aromatica
Pathway
tak00300
Lysine biosynthesis
tak00550
Peptidoglycan biosynthesis
tak01100
Metabolic pathways
tak01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tak00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tharo_2461
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tharo_2461
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tharo_2461
Enzymes [BR:
tak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tharo_2461
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Motif
Pfam:
Mur_ligase_M
UBM
Motif
Other DBs
NCBI-ProteinID:
AVR89358
UniProt:
A0A2R4BPU6
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Position
complement(2632652..2634064)
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AA seq
470 aa
AA seq
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MAHLTGGRWRHLPADGLRLSGIHFYLPYVTAGDLFVYLPREGAAAGVAAESIERAFCQGA
AAALVPKGAIPDARHPLLEVADTEKALQDLATGASLKFDGSRVLVTGSHGKTGFKNQLHH
LIRNQIPVHAYLGSANKELPVLRAIASLTRDARVFIVEVAVPGRRIGRDRAFFVRPDFCV
ITGIAPEHLKSHRSMDRLLHNKAEVTAGLRPGGRCLLNGDDVEFPGLRTAVAECSACEVL
VFGSAPGSAGRLLSARFEGMGWRVEAEILGERIAYDLPLLECYAPLTSVGVLLQARLLGA
DLAACVAEYAGYRHFGSSGNLYRVPLGCSSFFIYDQSTRAELRGFEAMFELMSRLRPGPG
GRKIVVMSELFDIEDNPGMVVDYPKMQTLMAAAGIDRLYTIKDFMQHRAALPASIGWHRH
AAIPADIRDELLADMRENDMIFLRADPPARLDVLAEALRRAGDGPAEQLY
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atggcgcacctgacaggtgggcgctggcgtcacctgccggcagatggattacgtctttcc
ggaatccatttctacctgccttatgtcactgctggtgatctctttgtttatctgccgcgt
gaaggcgcggcggctggcgtggctgcggagtcgatcgagcgtgccttttgccagggagct
gctgcggcgttggtgccgaaaggcgcaattccggatgcacgccaccccttgctcgaggtg
gccgatacggagaaggcgcttcaggatttggcaactggtgcaagcctcaagttcgacggc
agtcgcgtgctggttaccggatcccacggcaagacggggttcaagaaccagctccatcat
ctcattcgaaatcagatccctgttcatgcctaccttggcagtgccaacaaggaactgccg
gtgctgcgcgccatcgcttctctgaccagggacgcacgggtgttcatcgtcgaggtggcg
gtgccggggcgtcggattgggcgcgaccgggccttcttcgtgaggcccgatttctgtgtc
attaccggcattgcacccgaacatctcaaatcccatcgttcgatggacaggctgctgcac
aacaaggcggaggtgacggccggattgcggccgggaggccgctgtctgctgaacggggat
gatgtcgagtttccaggcttgcggacagccgtcgccgagtgttccgcgtgtgaggtgctg
gtttttggttcggcacccggttccgccgggcgcctgctttcggcccgcttcgaggggatg
ggctggcgcgtggaggcggagatcctcggcgagcgcatcgcctacgatctgccgttgctg
gagtgctatgcgccactgacttcggtgggtgtcctgctccaggcgcggctgctgggtgca
gacctggcggcctgcgttgccgaatatgccggctatcgccacttcggcagcagcggcaat
ctctatcgggtgcctctgggatgcagcagtttctttatctatgaccagagcacgcgtgcc
gaattgagagggttcgaggcgatgttcgagttgatgtcccggttgcggcccggtccgggc
ggacgcaagatcgttgtcatgagcgaattgttcgacatcgaagacaatcccggtatggtg
gtcgattatccgaagatgcagacgctgatggctgctgccggtatcgaccggctttatacc
atcaaggatttcatgcagcatcgcgcagcgctgcccgcctcgatcggctggcatcggcac
gcggccatcccggcggatatccgtgacgaactgctggcggacatgcgtgagaacgacatg
atatttctgcgcgccgatccgccggcccgcctcgacgtgcttgcggaagccttgcggcgt
gcgggcgatggtcctgcggaacaactctactga
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