Tyto alba (Barn owl): 104358593 Help Entry 104358593         CDS       T07816                                  Symbol RYR3 Name (RefSeq) ryanodine receptor 3   KO K04963   ryanodine receptor 3 Organism tala  Tyto alba (Barn owl) Pathway tala04020   Calcium signaling pathway tala04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tala00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     104358593 (RYR3)    04020 Calcium signaling pathway     104358593 (RYR3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tala04040]     104358593 (RYR3) Ion channels [BR:tala04040]  Voltage-gated cation channels   Ryanodine receptor    104358593 (RYR3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 TBK1_ULD Motif Other DBs NCBI-GeneID:  104358593 NCBI-ProteinID:  XP_032840611 LinkDB All DBs Position Unknown AA seq 4876 aa AA seqDB search MAEGGEGGEDEIQFLRTDDEVVLQCVASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKYVP PDLCICNFVLEQSLSVRALQEMLANTGDNATEGFIRKAAQGGGHRTLLYGHAILLRHSFS EMYLTCLTSSRSQTDKLAFDVGLRENAAGEACWWTIHPASKQRSEGEKVRIGDDLILVSV SSERYLHLSISNGSIQVDASFMQTLWNVHPTCSGSSITEGYLLGGHVVRFFHGHDECLTI PSTDQNDSQHKKVLYETGGAGVRARSLWRVEPLRISWSGSNIRWGQPFRLRHITTGKYLA LNEDEGLAMLDREKSDTTSTAFCFRVSKELKEKQDSSLKRDMDGMGVPEIKYGDSICFVQ HVASALWLTYKAQDAKSARLGPLKRKVILHQEGHMDDGLTLQRCQHEESQAARIIRNTTS LFSHFISVNNRTLSPTALPIEEMAQTLQDLITYFQLPEEDLEHEDKQSKLRSLKNRQNLF KEEGMLALVLNCIDRLNDYNSAAHFAGIAREDHGTAWKEILNLLYKLLAALIRGNRNNCT QFSSNLDWLISKLDRVESSSGILEVLHCILIESPEALNIIAEEHIKSIISLLDKHGRNYK VLDVLCSLCVCNGVAVRANQNLICDNLLPRRDLLLQTRLINDVTSIRPNIFLGVAEGSAQ YKKWYFELIIDHVDPFLTAEPTHLRVGWASTSGYAPYPGGGEGWGGNGVGDDLYSYGFDG LHLWSGRVPRAVASVNQHLLASDDVVSCCLDLGVPSISFRINGQPVQGMFENFSTEGFFF PVVSLSAGVKVRFLLGGRHGEFKFLPPSGYAPCYEALLPKEKMKLEPVKEYKRDSDGVRD LLGTTQFLSQASFIPCPIDTSQIALPFHLEKIRDKLAENIHELWGMNKIELGWTYGKIRD DNKRHHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHAHPAAEEDLKKVKLPKN YMMSNGYKPAPLDLSEVKLLPSQEFLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNKRN PRLVPYALLDERTKKSNRDSLREAVRTFAGYGYSIEPPDQEIADQTVEKVSIDKIRFFRV EQSYAVKSGKWYFEFEAVTGGDMRVGWARPACRPDIELGADDQAFVFEGSKGQRWHQGSG FFGRSWQPGDVVGCMINLDDKSIIFTLNGELLITSKGSELAFADFGIETGFVPICALGLS QIGRMNLGMDASTFKYYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKNHPHIEI WRIDGTIESPPRLKVTHKTFGTQNSNSDMIYCRLSMPIEFRSSFNFSVGVENTSSDVFQK RKHSQEIAPPYTTCFYSLRIFAGQDPSSVWVGWVTPDYHFYSENFDLNKNCTVTVTLGDE RGRVHESVKRSNCYMVWGGDVIANSQRSGRSNVDLEIGCFVDLATGMLSFTANGKELGTC YQVEPNTKLFPATFVQPTSTNLVQFELGKLKNTMPLSAAIFKSEERNPVPQCPPRLDVQT ITPVLWSRMPNSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDL MKFHYHTLKLYSSVSALGNTRVAYALCSHVDISQLFYTIDNQYLPGLLRSGFYDLLISIH LEHAKQAKLMMNNEFIIPVTDETRTIKLYPDETKKHGLPGVGLSTCLKPGFNFSTPCFIV TSEERQTSSPEIPLDTLKSKAISMLTEAVQCSGAHIRDPVGGQVAFQFVPVLKLIATLLV MGIFDDDDVKQVLLLIDPNVFGDHKEETEERTEKEEVTQVEEKAVEAGEKAIKVTKAPAK GLLQTRLPESVKLQMCHLLNYFCDCELQHRVEAIVSFADRYVSKLQYNQKYRYNELMQAL NMSAALTAKKTKEFRSPPQEQINMLLNFQLGEDCPCPEEIRDELYEFHDDLLIHCGIPLE EEEEEEEDSSLTGKLRSLMYKIKGPPKAEKVEPKEEEDKSPTTLKELISQTMVRWSQEDQ IQDPELVRIMYTLLRRQYDSIGELLQALRKAYTISAASVKDTINLLAALGQIRSLLSVRM GKEEELLMINGLGDIMNNKVFYQHPNLMRVLGMHETVMDVMVNVLGGDRSQIVFPKMVAS CCRFLCYFCRISRQNQKAMFEHLSYLLENSSVGLAFPSMRGSTPLDVAAASVMDNNELAL ALEEPDLDKVVTYLAGCGLQSCPVLLAKGYPDIGWNPIEGERYLSFLRFAVFVNSESVEE NASVVVKLLIRRPECFGPDLRGEGGNGLLAAMQEAIRISENPTRDLPSQSYKREGDDEEE EEEEEIVHMGNAIMSFYSALIDLLGRCAPEMHLIQSGKGEAIRIRSILRSLVPTEDLVGI ISIPLKLSTVNKDGTVNEPDMSANFCPDHKAPMVLFLDRVYGIKDQSFLLHLLEVGFLPD LRASASLDTVSLSTTEAALALNRYICSAVFPLLKRCAPLFSGTEHHASLVDSMLHTIYRL SKGRSLTKAQRDTIEECLLAICHHLRPSMLQQLLRRLVFDVPLLNEYCKMPLKLLTNHYE QCWKYYCLPSGMGSYGIAAEEELHLTEKLFWGIFDSLSHKKYDPELFRMALPCLSAIAGA LPPDYLDTRIRSTLEKQTSVDPEGNFDPKPVSTANLVLPEKLEYIVSKYAEHSHDKWAFD KTNSGWKYGVSLDENMKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAMGWSLERTKEG GEAIIHQRENEKLRSISQSSQGNGYIPAPLDLSNVVLSRELQGMVEVMAENYHNIWAKKK KMELESKGGGSHPLLVPYDTLTAKEKSRDREKAQELFKFLQVNGIIISRGLNDMELDASS MEKRFAFKFLKKILKYVDSAQEFIAHLEAIVTSGKTEKSPHDQEIKFFAKVLLPLVDQYF TNHCLYFLSSPTKTLSSSGYASNKEKEMVASLFCKLAALVRHRISLFGSDSATMVNCLHI LAQSLDTRTVMKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNIN YTTVALLPILTSIFEHISQHQFGIDLLLGDVQVSCYRILCSLYSLGTGKNIYVERQRPAL GECLASLAAAIPVAFLEPSLNHYNPLSVFNTKSARERAILGMPDTVEEMCPEIPQLDGLI KEINDLAESGARYTEMPHVIEVILPMLCNYLSYWWERGSESVPPTAGPCCTMITSEHLSI ILGNILKIINNNLGIDEASWMKRIAVYAQPIISKARPDLLKTHFIPTLEKLKKKAIKIVM EEEQLRADSKTDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRANWLKKPDTDSDEL FRMVAEVFILWCKSHNFKREEQNFVIQNEINNLAFLTGDTKSKMSKAMQVKSGGQDQERK KSKRRGDLYSIQTSLIVAALKKMLPIGLNMCTPGDQELISLAKTRYSHRDTDDEVKEHLR NNLHLQEKSDDPAVKWQLNLYKDILKSDEPTDPERNVERVQRISAALYHLEQVEQPLRSK KAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLHGYQNYWIETEEYSFEEKLVQD LATPPKKEEEEEEETEKKQPDPLHQIILYFSRSALTERSKLEDDPLYIAYSAMMAKSCQE EEEEEEEEKEKTFEEKEMEKQRTLYQQARLHDRGAAEMVLQMISASKGHTGPMVVETLKL GIAILNGGNTIVQQKMLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVT EEGTLIVRERGEKVLQHDEFTRDLFRFLQLLCEGHNNDFQNYLRTQMGNTTTVNIIISTV DYLLRLQESISDFYWYYSGKDFIDESGQRNFSKALAVTKQIFNSLTEYIQGPCIGNQQSL AHSRLWDAVVGFLHVFANMQMKLSQDSAQIELLKELLDLLKDMVVMLLSLLEGNVVNGTI GKQMVDTLVESSSNVEMILKFFDMFLKLKDLTNSDAFKEHDPDGKGIISKKEFQKSMEAQ KQYIQSEIEFLLSCAEADENDMFNYVDFVERFHEPAKDIGFNVAVLLTNLSEHMPNDSRL QSLLEPAESVLNYFEPYLGRIEIMGGAKKIERVYFEISESSRMQWEKPQVKESKRQFIFD VVNEGGEQEKMELFVNFCEDTIFEMQLASQISETDSSERPEEEEEAEPCYVVDIGDDEDE EKSLETASAFAMACVAVKKNIANIFKMVTVKNLRKQYRKVRKMTVKEMVKVFFSFFWILF VGIFQLFFSIVWGIFQILWSTVFGGGLVEGAKNIKVTKILGDMPDPTQFGIHDDIMEAEK AEGVEHGIRAELVQFVKGEKGETDIISDIFGIHTKKEGGSKHGHDAGLGDIAEILGTDIQ SSLENTVRKKKGLQISEIAKEAETKRKAETEKADMEDGEKQDKAKEVQSEQLEEGKMKKK KRRHGQKIEKPEAVMANFFKALEIYQTKMLHYLARNFYNLRFLALFVAFAINFILLFYKV TEEPLDEVEEDSNLWNSFDEEEEEEGMVFFVLEESTGYMAPALRALAVIHTIISFVCVIG YYCLKVPLVVFKREKEVARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFV KRKVINKYGDLYGAERIAELLGLDKSALDFSPVEESEPEEASLVSWLSSIDTKYHIWKLG VVFTDNSFLYLAWYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTV GLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEI EDPAGDPYEMYRIVFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFIC GIGNDYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESFVWKMYQERCWDF FPAGDCFRKQYEDQLS NT seq 14631 nt NT seq  +upstreamnt  +downstreamnt atggctgaagggggtgaaggaggggaagatgaaatacagttcctacgaactgatgacgaa gtagtacttcagtgtgttgccagtattcacaaagaacaaaggaagttttgcttggcagct gagggacttgggaatcgtctgtgctttttggaaccaacatcagaagctaaatatgttcct ccggacctttgcatctgtaattttgtccttgaacagtccctttctgtcagagcccttcaa gaaatgctggccaacacaggggataatgctactgaagggtttataagaaaggcagctcaa gggggtggtcacagaaccctgctgtatggccatgctatactacttcgacattcgttcagt gaaatgtatttgacatgtttaacatcatcaagatcccagacagataaacttgcatttgat gtgggattacgagaaaatgcagcaggtgaggcttgctggtggacaatacaccctgcttct aaacaaagatcagaaggagaaaaagttcgaataggtgatgatcttatcctggtcagtgtg tcctctgaaagatatctgcatctctccatatcaaatggaagtattcaggtggatgcctcc tttatgcagacgctatggaatgtacatcctacatgctcaggaagcagtattacagaagga tatcttcttggtgggcatgtagtacgatttttccatggccatgatgagtgtttgacaatt ccatctacagatcagaatgattcacagcacaagaaagtactttatgaaactggaggagct ggcgttcgagcaaggtctttgtggagagtagaaccccttcgaataagctggagtggaagt aacatcagatggggacaacctttccgtcttcgacatattacaacaggaaagtacttggct ctgaatgaagatgaaggacttgcaatgttagacagagaaaagtcagacacaacatctact gccttttgttttagagtgtcaaaggagctaaaagaaaagcaggattctagtcttaaacgt gatatggatggaatgggagtcccagaaatcaagtacggtgattcaatctgttttgttcaa catgtggccagtgccttatggttgacttacaaagcacaagatgctaaatcagcacgttta ggtcccttgaaaagaaaggttatattacaccaagaaggtcatatggatgatggtctaacc ttacaaagatgtcagcatgaggaatcccaggctgcccgaatcattcgcaatactaccagt ttattcagccattttataagtgtaaataacagaacactatcacccactgccctgcctatt gaggagatggctcagactctgcaagacctgattacttacttccagcttcccgaagaagac ctggaacatgaagataagcaaagcaagcttcggtcactcaaaaacagacaaaatctattc aaagaagagggaatgctggcactagttttgaactgcattgatcgcttaaatgactacaac agcgcagctcattttgcaggaattgcaagagaagatcatggtacagcatggaaagaaatt ttaaatctcctttacaaattgttagctgctctcatccgtggcaacagaaataattgtact cagttttccagtaacctcgattggctaataagcaaattggacagagtagaatcttcctca ggtatcttggaagtgttgcactgcatcttgattgaaagcccagaagctttaaatataata gctgaggagcacatcaaatccattatttcattgttggataaacatgggcgcaattacaag gttctcgatgtgctttgctctctttgtgtctgtaatggagttgcagttcgtgctaatcaa aatttgatctgtgacaatctactgcctagaagagatttactcttgcaaacacgtttgatt aatgatgtgacaagcataaggccaaacatatttttgggtgttgctgagggctctgcacaa tacaagaagtggtactttgaattaataattgatcacgttgatccattcttgacggcagaa cccacccatttacgagttggatgggcctctacttcaggttatgccccctatcctgggggt ggggaaggatggggaggcaatggtgttggtgatgacctgtactcttatggttttgatggc cttcatctgtggtctggtcgagtacccagagctgtagcatctgtcaatcagcatttatta gcatctgatgatgtggttagctgctgcttggatttaggtgtacccagcatttcattccgt atcaatggacagcctgtacaaggaatgtttgagaacttcagtacagaagggtttttcttc cctgttgtaagcttatcagcaggtgtaaaagttcgtttcttactgggtggacgtcacgga gagtttaaatttcttcctccatctggctatgctccctgttatgaagcattgcttccaaaa gagaagatgaaacttgaaccagtgaaagaatataagagagactctgatggagtgagggat ttgctggggacaacacaattcctctcccaagcttcctttatcccttgtccaatagacacc agtcagattgctcttccttttcatcttgaaaagatcagggacaaactagctgaaaatatc catgagctgtggggaatgaataaaatagaactgggctggacatatggcaagatacgggat gataataaaaggcatcatccttgtcttgtggaattctcaaaattacccgagacagagaag aattataatctacagatgtcaactgaaaccctcaaaacccttttggcccttggatgtcac attgttcatgctcatccagcagctgaggaagatcttaaaaaagtcaaacttcctaaaaat tatatgatgtcaaatggatataaacctgcccctcttgatctttctgaagtgaaattgcta ccttctcaagaatttctggttgacaaactagcagaaaatgcacataatgtctgggccaaa gacagaataaaacaaggatggacctatggcattcagcaggatcttaagaacaaacgtaac cctcggctagtgccatatgctttattagatgaacgtactaaaaaatcaaacagagatagc ctccgtgaagctgttagaacatttgcgggctatggttatagcattgagccacctgatcaa gagatagctgaccaaacagtggaaaaagtcagcatcgacaagatacgatttttcagagta gaacagtcttatgcagtgaagtctggaaagtggtacttcgaatttgaagctgtgacaggt ggagatatgcgtgttggctgggccaggccagcctgtcgacctgacatagagttgggagcg gatgaccaagcatttgtatttgaaggaagcaaaggccagcgttggcatcaaggcagtgga ttctttggacgaagctggcaaccaggagatgtggttggttgtatgataaacttggatgac aaatcaattatatttactctgaatggagagttgcttataaccagtaaaggttcagaactt gcgtttgctgattttggaatagaaactggttttgttccaatttgtgcactgggtctatct cagattggtcgtatgaaccttggaatggatgccagtacattcaagtattacacaatgtgt ggccttcaagaaggttttgaaccttttgctgtcaacatgaaccgagatgttgctatgtgg tttagtaaacgcttaccaacatttgtcaatgtgccaaaaaatcatcctcacattgagata tggagaattgatggaaccattgagagtccacctcggttaaaagttactcacaaaacattt ggcacacagaacagcaattcagacatgatatattgtcgtttgagtatgcccattgagttc cgctcatcattcaacttcagtgtgggtgtggaaaatacttcatctgatgttttccaaaaa cgaaagcacagccaagaaattgctcctccttatactacatgtttttattcactacggata tttgctggccaagacccatcctctgtctgggttggctgggtaacaccagactatcatttt tacagtgagaattttgacctaaataaaaattgtacagtgacagttactttaggtgatgag agaggcagggttcatgaaagtgtgaagcgcagcaattgctatatggtttggggaggagat gtaattgctaattcccagagatcaggtcgcagtaatgttgatttagaaattggatgcttt gttgacctggctactggaatgttgtcattcacagccaatggaaaagagcttggcacttgt tatcaggttgaaccaaacacaaagctttttccagcaacttttgtacagcctacaagcact aacttagttcagtttgaacttggtaaattaaagaatactatgcctttatcagcagcaatt tttaaaagtgaagaaagaaatcctgttcctcagtgtcccccacgccttgacgtgcaaaca attacacctgttttatggagcaggatgccaaacagctttctaaaagtagaaactgagcgt gtcagtgaacgtcatggctgggttgtgcagtgtttggaacctcttcagatgatggcactt catatcccagaagaaaacagatgtgttgatattttggaattatgtgaacaagaagatttg atgaagtttcactaccacactttaaaactctatagctcagttagcgctctaggtaatact agagttgcttatgcactttgtagccacgtggatatatctcagctgttttatacaatagat aatcaatacttacctggactcctacgttctggattctacgacttgctcattagtattcat ttggagcatgccaagcaagccaagctcatgatgaacaatgaatttatcattccagttaca gatgaaactcgaactattaagttatatcctgatgaaacaaagaaacatggtttacctgga gtagggcttagcacttgtctgaaaccaggctttaatttttctactccatgctttattgtg accagtgaagaacgtcagacatccagcccagagatacctcttgatacacttaaatccaag gccataagtatgctaacagaggcagtacagtgtagtggtgctcatatacgcgaccctgtt ggaggacaggttgcattccagtttgttcctgttcttaaactgatagcaacattgcttgta atggggatttttgatgatgatgatgtgaagcaggtgttacttctcattgatcccaatgtg tttggagatcacaaggaagaaacagaagagagaacagagaaggaagaggttacacaagtt gaagaaaaagccgtagaagctggggagaaagcaataaaagtaacgaaagcacctgcaaag ggcttattgcagacaagattgccagaatctgttaagcttcagatgtgtcatttactcaat tatttctgtgactgtgagctacaacatagagtggaagcaattgtatcatttgcagaccgt tacgtatcaaaattgcaatacaatcagaaatacaggtacaatgaactcatgcaagccttg aacatgtctgctgctttgactgccaagaagactaaagaatttcggtctcctcctcaagaa cagattaatatgttgctgaattttcaactgggggaggattgtccctgtccggaggaaatt cgtgatgagttatatgaatttcatgacgatcttctaattcactgtggtattccactagaa gaggaggaagaagaagaggaagattcctccttgactggcaaactccgttcattaatgtac aaaatcaaaggtccaccgaaagcagaaaaagtagaacctaaggaggaagaagataaatct cctactacactgaaagaactcatatcccagactatggtgcgctggtcccaggaagatcag attcaagatccagaattagttcggattatgtacaccctccttcgtaggcagtatgacagc attggtgagctactgcaagctctgaggaaagcatacactattagtgctgcctctgtgaag gataccattaatctgcttgcagcactgggccagattcgctcacttctcagtgtcaggatg ggaaaagaggaggaattgctaatgattaatggattaggggatataatgaacaacaaggtg ttttatcagcatcctaacttaatgagagtcttgggcatgcatgagactgttatggatgtg atggtgaatgtgcttggaggagatagatctcagatcgtttttcctaagatggtggcaagc tgttgtcgattcctctgctacttctgccgaattagtcgtcaaaaccaaaaggccatgttt gagcatcttagttacttactggaaaacagcagcgttggactagcatttccttcaatgaga ggttcaacaccactagatgttgcagcagcctctgtaatggacaacaatgagcttgcacta gcattggaggagccagatcttgataaggttgttacctacctggcgggttgtggcctgcag agttgtccggtgttgctggctaaaggatatccagacattggatggaacccaatagagggt gaacgttacctgtcattcttaagatttgcagttttcgttaacagtgaaagtgttgaggaa aatgcaagcgttgttgtcaagctccttattcgacgaccagagtgctttggaccagacctt aggggagagggaggaaatggtttgctggcagctatgcaggaagctatcaggatctcagag aatcctactcgtgaccttccttcccagtcatacaaaagagaaggtgacgatgaggaggag gaagaagaggaggagattgtgcacatgggcaatgcaatcatgtcattttactcagctctc atagatttacttggacgctgtgcacctgaaatgcatcttattcaaagtggaaaaggggaa gctattcgaatcaggtcaatccttcgatctctagtgccaactgaagatttggttgggatt ataagtatacccctaaagctgtcaacagttaacaaagatggcacagtaaacgagccagac atgtctgcaaatttctgccctgatcataaagcacccatggtactcttcttggaccgtgtc tatggtattaaggaccaaagcttcctccttcacctactggaagttggatttttaccagat ttaagagcctctgcctctttggatacagtttctctaagtaccacagaagcagctctcgca ctaaatagatatatttgctcagctgtgtttccattactcaaaagatgtgctcccctcttt tctggaacagagcatcatgcctctctggttgactccatgcttcacacaatatataggtta tccaagggacgttcccttacaaaagcacaaagagacactattgaagaatgcctgcttgcc atttgtcaccacttgcgtccctctatgctacaacagctgttgagaaggctagttttcgat gtgcccctactcaacgaatactgtaaaatgccgctcaagcttctgacaaatcactatgag cagtgctggaaatattattgtctgccttcaggaatgggaagctatggaattgcagcagaa gaagaattacatttaactgaaaaactgttctggggaatatttgattccttgtctcataag aagtatgatccagagctctttcgaatggctttgccttgtctaagtgctatagctggtgcc ttgccccctgattatttagatacacgaattaggtcaactttggaaaagcagacttcagtt gatccagaaggaaattttgatcccaaacctgtcagcacagcaaaccttgtacttcctgaa aagttggagtatattgtcagcaagtatgctgaacattcccatgataaatgggcctttgat aagactaatagtggatggaaatacggtgtttcactggatgaaaatatgaagactcaccca ttaataagacctttcaaaactttaactgaaaaggaaaaggaaatttatcgttggcctgcc agagaatcactgaaaaccatgttggccatgggatggagcctagaaaggaccaaggaagga ggagaagcaattatacatcagcgtgaaaatgaaaagctccgcagcatatctcagtctagc cagggaaatggatatatcccagcaccacttgatctctctaatgtggtgctttctagggag cttcagggaatggttgaggtaatggcagaaaactaccataatatatgggccaaaaagaag aaaatggagttggaaagcaaaggtggaggtagtcatcccttattggtaccttacgacaca ttgacagccaaggagaaatcacgggaccgtgaaaaggcacaagagctgtttaaattcctt caagtcaatggtataatcatatctcggggtctgaatgacatggaattggatgcttcatcc atggaaaagaggtttgcctttaagtttctgaagaaaattttaaaatatgttgattctgct caagagtttattgcgcacttagaagccattgtaaccagtggaaaaactgaaaaatctcca catgaccaagaaataaaattctttgccaaagttcttttaccattagttgatcagtacttt acaaatcactgcctctacttcctgtcttctccaacaaaaacactcagtagcagtggatat gcatcaaataaggaaaaggaaatggtagcaagcctgttctgcaaacttgctgctcttgtt agacataggatttcactttttggtagtgattctgctacaatggtgaactgcctgcacatc ttggctcagtctcttgatacacgaactgttatgaaatcaggatctgagcttgttaaagct ggtttgcgcgccttttttgaaaatgcagctgaagacctggaaaaaacttcagaaaatctt aaacttggaaaatttacccattcacgaacacaaatcaagggtgtttcacagaatatcaat tatactacagtagcattgttaccaatattgacatcaatttttgaacatatttcacaacac cagtttggaattgatttacttttgggtgatgtacaagtttcatgttacagaattctttgt agcctctattcccttgggactgggaagaacatctatgttgaacggcagcgtcctgcactt ggtgagtgtttagcatctcttgcagcagccattccagtagcattccttgaaccttctctc aaccattacaacccattgtctgtgttcaacacaaaaagtgcaagagagagagcgatttta ggtatgcctgatacagtagaagagatgtgtccagagatccctcaattggatgggctaata aaggaaattaatgatttagcagagtctggagcaaggtatactgaaatgcctcatgtaatt gaggttatcttacccatgctatgcaactatttatcctactggtgggaaagagggtctgag agtgttcctccaactgctgggccttgctgtacaatgataacatctgagcatctgagcatc attcttggaaacattctgaaaatcattaacaacaatctgggaatagatgaagcatcttgg atgaaaagaattgcagtttatgctcaacctatcatcagcaaagccaggcctgatctgctc aaaacacactttattccaacactggagaaattgaagaagaaagctataaagattgtgatg gaagaggagcaactgagggcagatagtaaaactgacacccaagaagctgagttactcatt cttgatgagtttgctgttctctgtagggacctttatgccttctatccaatgttgatacgt tatgtagacaacaatagagccaattggctgaagaaaccagacacagattctgatgaactt tttcgaatggtagctgaagtttttatcctgtggtgtaaatcgcataatttcaaaagagag gaacaaaattttgtgattcagaatgaaatcaacaatttggcatttttaacaggggacacc aagagcaagatgtctaaagccatgcaagtaaagtctggaggacaagatcaagagagaaag aaatcaaaacgtagaggggatttgtactccatacaaacatccttgattgtagctgcactt aaaaagatgcttcctattggtttgaatatgtgtactcctggggatcaagagctcatctct ttggcgaagactagatacagccatagggatactgatgatgaagtcaaagagcatttacgt aacaatttacatttgcaggaaaagtctgatgatccagctgtgaaatggcagttaaatctg tacaaagacattttgaagagtgatgaacctactgatcctgagagaaatgtggaacgtgtg cagaggatatcagctgctctgtatcatctggaacaggttgaacaaccactgagatcaaag aaagctgtttggcacaaactcctgtcgaaacaacgcaaaagggctgttgttgcgtgtttc cgaatggcaccattatataacctgccaaggcaccgttctattaacctcttcctccatggc tatcagaactattggatagaaacagaggaatattcatttgaggagaaactagttcaggat ttggctacacctccaaaaaaagaggaagaagaagaggaagagactgagaaaaaacaacct gatccacttcatcagattatcctctattttagtcgcagtgctctcacagagagaagcaaa ctagaagatgatcctttatatattgcctattccgccatgatggcaaagagctgtcaggaa gaagaagaagaggaagaagaagaaaaagaaaagacatttgaggagaaagaaatggaaaaa cagagaactctgtatcagcaagctcgcttacatgatcgtggagctgctgagatggtcctt cagatgattagtgcaagcaaaggtcatacaggacccatggttgttgaaacactaaaactt ggtattgctattctaaatggtgggaataccatagttcaacagaaaatgctagactacctg aaggagaaaaaggatgctggattttttcaaagtctgtctggcttgatgcagtcctgcagt gttcttgacttgaatgcgtttgaaagacaaaataaagcagaaggcctgggaatggttacc gaagaaggaactctcatcgttcgtgagcgtggtgaaaaagtgttgcagcatgatgaattt actagagatctatttagatttttacaactgctctgtgaagggcataacaatgattttcaa aattaccttcgtactcagatgggcaacaccacaacagtgaatattattattagtacagtc gactacctcttgcgtcttcaggaatcaatcagtgacttctattggtactattcaggaaag gatttcattgatgaatcaggacaacgtaacttctccaaagctctggctgtcaccaaacaa atattcaattcccttacagaatatattcagggcccttgcataggtaaccaacagagtctg gctcatagtaggctgtgggatgcagttgttggctttcttcatgtctttgccaatatgcag atgaaactctcacaggactctgctcagatagaattgcttaaagaacttctagatctgcta aaggatatggtagtgatgctcttgtcactgcttgaaggtaacgttgtaaatggaactatt ggaaaacaaatggtagacacgcttgtagaatcatctagcaatgtagaaatgattttgaag ttcttcgacatgttcctcaagttaaaagatctgactaactcagatgctttcaaagagcat gacccagatggtaaaggcatcatttcaaagaaggaattccagaaatcaatggaggctcag aaacaatacatccagtcagagattgaattcctgctgtcctgtgcagaagctgatgaaaat gatatgtttaactatgttgattttgtggaaagattccatgaaccagccaaagacattgga tttaatgtagcagttctgctaacaaacctttcagagcacatgcctaatgattcacgcctt cagagcttacttgaacctgcagaaagtgttcttaattactttgaaccgtatcttggccgt attgaaataatgggtggagccaagaaaatagaaagagtttactttgaaatcagtgaatcc agtagaatgcagtgggagaagcctcaggtgaaggaatccaaaaggcagttcatctttgat gttgtaaatgaaggtggagagcaagaaaaaatggaactctttgtgaatttctgcgaagac acgatctttgaaatgcagttagcatcccagatctctgaaacagattcatccgagaggcct gaggaagaggaagaggcagagccttgttacgtagtggatattggagatgatgaggatgaa gaaaagtccctggaaactgcttcagcttttgcaatggcctgtgttgcggtgaagaagaac attgccaacatttttaaaatggtcactgtgaagaacctaaggaaacaatacaggaaagtg agaaagatgacagtaaaagagatggtgaaagtgtttttctcctttttctggatcctattt gtagggatcttccaactgttcttcagtatagtgtggggaattttccagattctttggagc actgtgtttgggggtggcctggtcgaaggagccaaaaatattaaagttaccaaaatatta ggggacatgcctgacccaacacagtttggaatccatgatgatattatggaagcagaaaaa gctgaaggtgttgagcatggcatcagagctgaactagtgcagtttgtgaagggtgaaaag ggagaaactgatataatttcggacatttttggcattcatacaaagaaagaaggtggctca aaacatggtcatgatgctggacttggagatattgcagaaatccttggtacagatatccag tcatctttggaaaacacagttcgtaagaaaaaaggattacagatatctgaaattgcaaaa gaagctgaaacaaaaagaaaagcagaaactgagaaggctgacatggaagatggtgagaaa caagataaagcaaaggaagtacaatctgagcagctggaagaagggaaaatgaagaaaaag aagcgaaggcatggacaaaaaattgagaaaccagaagctgttatggctaacttcttcaaa gctttggaaatttatcagacaaaaatgcttcactacttggcaagaaatttttataactta aggtttcttgctctatttgttgcatttgccatcaactttattcttctattttataaggtg acggaagagccacttgatgaagtagaggaagactctaatctctggaactcttttgatgaa gaggaagaggaggagggcatggtgttttttgttttagaagaaagtacaggttacatggca cctgctctcagagcattggcagttattcatactatcatctccttcgtctgtgtgattgga tactattgcttaaaggtccctctagttgtattcaagagagaaaaggaggtagctagaaag ctggaatttgacggactatacataactgaacagccatctgaagatgatattaaaggacag tgggatcgcctggttataaataccccgtcctttcctaacaattactgggacaaatttgta aaacggaaggttattaacaagtatggagacttatatggagcagagcgcatagcagaactt ctgggcttggacaaaagcgcccttgattttagtccagtggaagagagtgaaccagaagag gcatctcttgtatcatggttaagctccattgatacaaagtaccacatttggaagcttgga gttgttttcactgataattcgtttttatacttagcttggtatacgactatgtctatcctt gggcactacaacaacttcttctttgctgctcacctactggatattgctatgggcttcaag acactgcgaaccattttgtcttcagtcactcacaatggcaaacagcttgtgcttactgta ggactccttgctgtagtagtgtatctttacactgttgtggcgttcaacttcttccgcaaa ttctacaacaaaagtgaagatgaagatgaaccagacatgaagtgtgatgacatgatgacg tgttatctgttccacatgtatgtgggcgtaagagctggtggtggcattggagatgaaatt gaggatcctgctggagacccttatgaaatgtatcgaattgtctttgacatcacattcttc ttctttgtcattgttatcctactggctattattcaaggtctgattattgatgcttttggt gaattaagagaccagcaagaacaagtgagagaagatatggagaccaaatgttttatttgt ggaattggcaatgactattttgacacaaccccacatggctttgaaacgcatactttgcaa gaacacaacttggcaaactatttgttctttttaatgtatctcattaacaaggatgaaact gagcataccggccaggagtcatttgtgtggaagatgtaccaagaaagatgttgggatttt ttcccagcaggggactgcttccggaaacagtatgaggatcaacttagctaa

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