Tyto alba (Barn owl): 104359285 Help Entry 104359285         CDS       T07816                                  Symbol MDN1 Name (RefSeq) midasin isoform X1   KO K14572   midasin Organism tala  Tyto alba (Barn owl) Pathway tala03008   Ribosome biogenesis in eukaryotes Brite KEGG Orthology (KO) [BR:tala00001]  09120 Genetic Information Processing   09122 Translation    03008 Ribosome biogenesis in eukaryotes     104359285 (MDN1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03009 Ribosome biogenesis [BR:tala03009]     104359285 (MDN1) Ribosome biogenesis [BR:tala03009]  Eukaryotic type   Pre-60S particles    Other pre-60S particles     104359285 (MDN1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_5 AAA_lid_7 AAA_lid_5 AAA AAA_3 AAA_16 AAA_7 AAA_22 nSTAND3 TsaE AAA_18 Sigma54_activ_2 AAA_14 ABC_tran AAA_6 bpMoxR Dynein_heavy DUF815 MDN1_4th PduV-EutP Motif Other DBs NCBI-GeneID:  104359285 NCBI-ProteinID:  XP_042658921 LinkDB All DBs Position Unknown AA seq 5578 aa AA seqDB search MAAAAAMSMAELRFRLAEPLQLVARRNEKSGAELSRFLAKQIWTQQDRQCILDTLAQLLL DKECTLLIGRQVRPILLDLLERNAEAIKAGGQINHDRHERLCVAMSKLVSDHPDILPFAL RYFKNTSPVFQRLFLESSDTNTVRYGRRRMKLRDLMEAAYRFLQKEPSVFRELWDWSVCI PLLRSHDTLVRWYTSNCLALVTCMNDEHKLSFLKKIFNPEELIHFRLKLLEESQLQNVEQ ALVLANPDSSFWQKEKEMQYTQGHIVPGDLSANVVAVCGIVLPRLQLVSEDQGNNTSHFV LVESAFTNLQNLAIAVAYQSPVLLEGPIGCGKTSLIEYLAAVTGRAKPPHILKVQLGDQT DSKTLLGMYRCTDVPGEFVWQPGTLTQAVTKGHWILLEDIDYAPLDVISVLIPLLEKREL LIPGRGDCLKVASGFQFFATRRIFSCGGGWYRQQNSHAALLDKYWTKIHLDNMSTGELKE VLQKRYPNLALVTDHLLDIYIDLTGGKYQASENGASGSGHIPEDSSESRSENKKPNLEGR ELSLRDLLNWCSRIAYNFDSNSSTTSVNIFQEALDCFTAMLSSQGSRQKMAKVIGSKLNI SKKKVEFFCELYKPEILIREQEVAVGRVHLMKKQTQTLTVQRAKQTFAATRPSAVLIEQL AVCVVKGEPVLLVGETGTGKTSTVQYLAHITGHHLRVINMNQQSDTADLLGGYKPVDNKL IWLPLRESFEELFSQTFSRKKNQTFLGHIQTCYRQKRWHDLLKLMQHIHKSASNKEAKEN ASGSPLKEKWEAFGLKLNHAHQQMKMTENALLFAFVEGTLAQAVKKGEWILLDEINLAAA ETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFT ELYVEELKNEGDLQVLIMDYLRGLNVNKNTVQGIVNFYLSVRKEAETKLVDGTGHRPHYS LRTLCRALRFAASNPCSSIPRSLYEGFCLSFLTQLDRDSHPVVQKLICQHIVSGNIKSLL KQQIPKPQGGRFVYIEGYWISAGDKEPTVDDTYVLTPSVKLNLKDIARVVSAGTHPVLIQ GETSVGKTSLICWLAAATGNHCVRINNHEHTDIQEYIGCYTSDASGKLIFKEGILIDAMR KGYWIVLDELNLAPTDVLEALNRLLDDNRELFITETQEVVKAHPRFMLFATQNPPGLYGG RKVLSRAFRNRFVELHFDELPSAELETILHKRCSLPPSYCSKLVKVMLDLQSYRRGSTVF AGKHGFITLRDLFRWAERYRLAEQLEKEYDWLQHLANDGFMLLAGRVRKQEEVDVIQSVL EKHFKKKLYPESLFSGESIKNLLAKSSMQTSVMDRGFNHIVWTQGMRRLAILVGRALEFG EPVLLVGDTGCGKTTICQIFAALTNQKLYSVNCHLHMETSDFLGGLRPVRQRSRDQEESD GSRLFEWCDGPLVLAMKEEGFFLLDEISLADDSVLERLNSVLEAEKTLVLAEKGGRDDEE NEVELLVAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSNGRDDLIQIVKHNLH PGLSLGGINHQGADIAELMMDFVEWLTNQEFGRQCILSVRDVLSWVNFMNVMVEDEESNS AKEYSLLYISPMMSFIHAACLIYIDGIGSGTTSCSADTALLAREKCLAFLCEKMSQFLEL TDSQKNELKIYDRTKEKEFVWRDNFMGIHPFFIPRGPVLQRNSITDYALNAGTTALNAQR LLRALQLNKPILLEGSPGVGKTSLVAALAKASGNCLVRINLSEQTDVTDLFGTDLPVEGG KGGEFAWRDGPLLAALKAGHWIVLDELNLASQSVLEGLNACFDHRAEIYVPELGMNFHVQ HKMTKIFGCQNPYRQGGGRKGLPKSFLNRFTQVYVDPLSAEDMEFIGNTLFPAIDKIIIA KMVAFNNKIDKEVMAEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYEPGQHVFLVYG ERMRTREDKEKVISIFRDIFGQEADVYTGTREFHITPYNVQVGYSVLSRGNCIPHPGRNL SLLHHSLQSLESIMKCVHMSWMVILVGPAAVGKTSLVELLAHLTGHRLKIMAMNSAMDTT ELLGGFEQVDINRPWQRLLEKVENAVSTLVRDSLLLTEICADDAELVLRAWSNFILNYKP KSLGEGGGSVTAELVSKLEGILVLTQRLNNKINSYSKAEFALLVEEFRRFKLQQAQAADC ISHGTFEWVDGMLVQALQSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTMSERGVIDGT IPTVAPHPNFRLFLSMDPVHGEISRAMRNRGIEIYIPGENDGNVLDNLDLKLLLHGVGLV GDSICDALMAVHSETKAAIAGSVSSLSPLLQAAVLIVQQLQRGLGLAKSFYRACWEVYGR SQQLQINQKLVLELVTKHASSLASHETWGDSLLAAGLWPDSLPTGLFAAEDSLLSTVRSD AQVLMYCLNRLNLKNCRTLPLTLQDLQTIMQSTNPESLKFSAVEIDADWMDNMEVLQASV KLFIEKATNQDWTLRVKWLNSIAKSLPQVLDPVRIQLEAGAVALGSFYASPLSSGVSNMI KLLQPTMTDEHVMSLDPRWNMQFLDIIRNSMNFDTEMEHTDQLLILLKSVANRAVLFLDR EKRSYTEKNLITSKKPRNSVLRMSLDFRKDPGSYSCLPHTIVVNLAAFFELWDAFAFHWV KSTQVALSDDDMHDILYCLLWRDRFWAVSDTLTVDSPGLSLLSLHWHWVMKHLIDRIPQM LIGSDQHKVSKDIQSVSQQIQSCLSNPAGISANMKMLQKSLGRPLPFKDKLGMECFSQLK VLSKPFNILELRLAFGESRWQEKICCLKIAATGWKMKKALLQADGLIIRANHTDDVNLGQ LKIFLKAVHSQLRAEGVVYSHSEERFAEDTVSSQLDPAFLNQLCSRVQLWPAMEHIGTLW QYKLTADYVAKACARRGNFSEELSMCSDLVQLLAFSLKLTPAASHQLSGLWHLLHLNEIP PEEMSLLSSQLINAALASFWSSTFTTDPDYWLTWRPLPITEEENFSKSHINSSMKGPGVL TRAVFSKCFFEILTSSSKTSQWDVSGLPVLSSSHVTLGEWMERAQQLHEVTTALWTNLAV SSIADFRHTDARLQGIMLSRQLSALVDLVPVDLQEEFLECCEKLYLKDPVAYEYLLKILR CITDQELLPKEFLFLLLTCLQQFFGEGLKELPETAWRGSLWVNIGLVQIQVWLPQTRFDP AVKREYKLKYAKEELYQLECEWKTNDFSFQLHTGKSIEDEAVSSCIHPHLRLLHERMQRL KEQISSLSRKKAFRPPAPPYDCLYQEAYQYINSIARVSSVQDLLARLLQFLHGERPKSLQ AIQNLLNEEASWQQSHHQFRKHLAEEYAVFPDAIIPLQAAILQLQHGMRLVASEVYAVLR SFVHPADLTNLLTSLLTFPSVGHTFPTYLARAEILCSVNSVEVLHGLKRFSLKHSEGESE GAEQTCPTLEQLLVNALLHLRCHVLSRGEMDQKSLQLFRHLCQAIINEWDEQERRARERE AMERSLYRYRSKSHGKGRSEEEQEEEEFRRRFPFHEKDFEDITAQPSLEEKMETEEPSED QLEIDRALLSKSSMQTVMMVHQQLCLNFARSLWYQRSLPAHQAKHYFSTFISCYQTGACL VSQFYPLIGAEMNDNLLGSQLLVSTLLHNTFFEELTSDLLLQQDGPYDFYQHPNIQQVRQ CQPVLDSFAKEVNGLLQEWPEHPVLVQLLVVMDRIRSFPLSSPLSKFLNGLEILLAKAQD WEENASRALSLRKHLDLVTQLIIQWRRLELNCWSVSLDNIMKQHVEKSTKHWFSIYQMVE KYVQEQTGVNTEDTEPMDLKTLVSTLQAFIEGSTLGEFHARLQALLVFHCHVLLMPQVAE KDILCSILWNLYNYYKQFSECIETRITELRQPIEKELKEFVKISKWNDVSFWAIKQSVEK IRRTLFKFMKKFEVVLDEPCQPALVEIGKEEQLDCLQKQEESENRETKVQRLNNTLRKIL SARTDVAKRALPEECQDGITFHTESLQYRLPKLTKKMKKMCTTVTENNSFLNLVENLDEF TGGIIVSVVELQNLTFDQTADKEKQKSEAKHIQMQKQRALSDLFKSLAKTGLSYRKGLSW SRSKDYHEILYLHPLDLRSALGVVNRTHDLDATLLTEVSSAWDGCQKYFYQSLARHSRLQ TALLAPSKDIGLGSIERCKGFTAHLMQVLVRQRQSLAALTEQWILLRNLLSCIQEIDSRL TADREYHVAFPPQDSMQCWTDKLQQLSMQCVMVLEELSWFMQCCPKEELTKCSDNERTDV KTNNFQSSGPEMGNVFTGIPDLIPSELKYLTPVTIEQLPPGCRMRNKDQLWLQVAAQLTA MLANVKAVKAEVDKIRQQSRETLFYSWRDFEVCISAMDCLLEVSAQLQGLESLFLPNGEG TQAANQMTLIKSLKYIQEVVNNTSADFLAWRTQLLASMSDCSGNQQTDEEFVEHFSAKVE TVIRVVLYAIQCLVERKQEDGKEEEKSTEENEDAASFDVIKAGHITKLLDEDLSADLDSL NVQKVILAVSELLENLKSYRGDYTSDKHKFFNQSCYLLVRLKPLLCKYSDLILFYLTVSL ASHRSTGKLLSVLTSIFTELAQKGFCLPKELLEDEAGEGATQFHDYEDGGIGDGEGKKDV SDKIESEDQIEDSFQKGEEKEKEDQDSKPDIEGEDNAIEMSEDFEGKMHDGEQEKKENDD SSDEEELDKQMGNLDNAEADDKLDERLWGDEDDDDDEDDASSKPEETGPGMDEEDSELVA KDDNSGTGNKDNKKQPPKDEEKEQQDDDSENKEKIHEQIDEREYDENEVDPYHGQQEKQT EVEPLDLPDNLNLENDEKSDEEEEDKEEENAFEVDEKPVDLTEAEKTEDQNQEDTGETER DDQDAEPAEEGISEEKEDEGDKDGDEQEENAGNTEDETEKEKEESQPPDEEKNESAEDKG IPAADQGLQPREEEGKDNSEMDEQIPEPEERMEHETEGQTGQENLQSDSAVELAGEASER DQSKEEYGSGASSANQSEGHESTRMARMASQKQSRKNTQSFKRKPGQADNERSMGDHNEH IHKRLRTIESSSEAKHNTNQPKQNVEEADAFEHIKQGSEFYDAQTYDVASKEQEKPIMPL EEKEEADSEDAAMEAEMQNNEDLRAVDTEELKPEKKNSTATKTPGPGDVEPEIQTFDSED VNDSTTEKLPKVTEEKPERSKDSTIHTAHQFLMDTPQHIVRDPEELRKELERQLEAWHTQ QSGTPDEEKEAAQLWQRYLVLTAPLSQQLCEQLRLILEPTQAAKLKGDYRTGKRLNMRKV IPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMIDNHSKQLAYESLAVIGNALTLL EVGQIAVCSFGETVQLLHPFHEQFSDQSGTRILRLCKFQQKKTKIAQFLESSANMFAAAQ QLSQNINPETAQLLLIVSDGRGLFLEGKERVTAAVQAAQNANIFVIFVVLDNPNSRDSIL DIKVPIFKGPGELPEIRSYMEEFPFPFYMILRDVNALPETLSDALRQWFELVTASDTL NT seq 16737 nt NT seq  +upstreamnt  +downstreamnt atggcggcggcggcggcgatgtcgatggcggagctgcggttccggctggcggagccgctg cagctggtggcgcgcaggaacgagaagagcggcgcggagctgagcaggttcctggcgaag cagatttggactcagcaggatcgtcaatgcatcctcgatactttagcacagttattactg gataaagaatgtacgctattgattggccgtcaagttcggccaatcttgttggatttgttg gaaagaaatgcagaggccattaaagctggtggccaaatcaaccatgatcggcatgaaagg ctgtgtgtagcaatgagcaagctagtttctgaccaccctgatattttgccatttgcttta agatattttaagaatacatcaccagttttccagagacttttcctggagagctcggataca aacacagtccgatatgggcgcagacgaatgaagctacgggacctcatggaggcagcatat agatttttacaaaaggagccatcagttttccgggaattatgggattggagtgtgtgtatt ccactcctaaggagtcatgacaccttagtccgttggtatacttcaaactgccttgcactg gttacatgcatgaatgatgagcataaattatctttcctgaagaagatattcaatcctgag gagctgatacatttcagactaaagctcctagaagaatctcagctgcagaatgtggaacaa gcccttgttttggccaatccagactcctcattttggcaaaaggagaaagaaatgcagtat acgcaaggacatattgtaccgggtgacctctctgcaaacgtggtagctgtatgtggcatt gtgctgcctagactgcagcttgtttctgaagatcaggggaataacaccagccattttgtt ttggttgaatctgccttcacaaatcttcaaaaccttgctattgcagtagcatatcagagt cctgttttattagaaggaccaataggatgcggcaagacttccttaattgaatatttagca gctgttacaggaagagcaaagccccctcatattttgaaagtccagcttggggatcaaact gatagtaagacgctgcttggtatgtatcgttgcacagatgtaccaggggagtttgtatgg caacctggaaccctgacacaagctgttaccaaaggtcattggatacttctggaggatatt gattatgctcctctggatgtgatctctgtgctgattcctcttttggaaaaaagagagttg ctgattcctggtcgtggtgactgtttgaaagtagcatctggattccagtttttcgcgacc agaaggatattcagttgtggcggaggttggtacaggcagcaaaacagccacgctgctctc ttggacaaatattggaccaaaatacatctggataacatgagtacaggagaactcaaggag gttcttcaaaagaggtaccccaatcttgctcttgtaactgatcacttgctagacatttac attgaccttacaggaggcaagtatcaggcatcagaaaatggtgcttctggctctgggcac ataccagaagattcatcagaatcaagatcagaaaataagaaaccaaatctggagggacga gaattatctctaagagacttactgaattggtgtagcaggattgcttacaacttcgacagt aattcttcaaccacatcagtgaatatttttcaggaggcattggactgtttcacagctatg ctgtccagccaagggagcagacagaaaatggcaaaagttattggaagtaaactaaacatt tccaagaaaaaggtagagttcttttgtgaactctataaaccagaaatcctaatacgggaa caagaagtcgctgtgggaagagtgcatctcatgaagaaacaaacacagactctcactgta cagagagcaaaacaaacctttgctgccacacggccatctgcagtattgattgaacagctt gcagtttgtgttgttaaaggagaacctgtgcttttggttggtgaaacaggaactggcaaa acctcaactgttcagtaccttgctcatattacaggacaccatttgagggttatcaacatg aaccaacagagtgacacggcagatctgttaggggggtacaagcctgtggataacaagctg atctggctacctctgcgagagtcttttgaagaactcttctctcagacattctctaggaag aaaaaccaaacgttcttgggacatattcagacctgctacagacagaaacgttggcatgat ctgctaaaactaatgcagcatattcataaatctgctagtaataaggaagcaaaagaaaat gcatctggctcaccactgaaggaaaaatgggaggcatttggtcttaaactgaatcatgct catcaacagatgaaaatgacagaaaatgctcttctctttgcatttgttgagggtactctg gcacaagcagtaaaaaaaggagagtggattttattggatgagattaacttggctgcagca gagactttagagtgcctgagtggtttattggaaggatcatctgggtccctggtgttatta gacagaggagacacagagcctctggtccgtcaccctgatttccgtttgtttgcatgcatg aatccagctacagatgttggaaagagaaatcttcctccaggaataagaaacaggtttact gaactttatgtagaagaattaaaaaatgaaggagacttgcaagttcttatcatggattat ctgaggggcttgaatgtgaacaaaaatacagtacaaggaattgtgaacttttatttatct gtgagaaaggaagcagaaacaaagctggtggatggaactggccacagacctcactatagt ctccgtacactttgcagggcactgagatttgcagcatctaacccatgtagcagcatacca cgctcactgtatgagggcttctgtttgagtttcctgacacagcttgacagagattctcac ccagtagttcagaagctaatttgccagcatatagtctctggcaacatcaaaagtcttctc aagcagcaaataccaaaacctcaaggagggagatttgtatatatagaaggatactggatt tcagctggggataaagagcctactgtagatgacacttatgtgctaaccccttcagttaag cttaatctgaaagacattgctagagttgtatctgcagggactcatccagtgctgattcaa ggagagacctctgttggtaaaaccagtttaatttgctggttggctgctgctactgggaat cactgtgtaaggattaacaaccatgagcatactgacatccaggaatatattggctgttat acatcagatgcctctgggaagttgatatttaaggaaggcattctcatagatgcaatgaga aagggttactggattgttctagatgaattgaatttggctcccactgatgttctggaggct ctcaaccgtttgttggatgataacagggagctgttcattactgagacccaggaagttgtc aaagctcaccctcgcttcatgctgtttgctacacagaatcccccaggactctatggtggc agaaaggttttgtccagagccttcagaaatcgttttgtggaactgcattttgatgaactg ccaagtgctgaactggaaaccatcctgcacaagcgatgtagtttgccaccttcttattgc agcaagcttgtcaaagtcatgttagacctgcaatcttaccgcagaggttcaacggtgttt gctgggaagcatgggttcattaccttgcgggatctgtttcgttgggctgaaaggtacaga ttggcagaacagctggagaaggagtatgactggcttcagcacttagcaaatgatggtttt atgcttctggctggcagagtcaggaaacaggaggaggtggatgttattcagagcgtcctt gaaaaacacttcaagaagaaactatatccagagtctctcttctcaggggaaagcattaaa aacctattggctaaatcctccatgcagacgtcagtgatggacagaggttttaaccacatt gtctggactcaagggatgaggagacttgccattttggtgggacgagccttggagtttggt gaaccagtactgctggtgggagacactgggtgtggtaaaactaccatttgtcagatcttt gcggcattaacaaatcagaagctatattcagtgaattgccacttgcatatggagacttca gacttcctgggaggactgcgaccggtcagacagaggtcgcgagaccaggaggaatctgat ggttctagactctttgaatggtgtgatggacctcttgttttagcaatgaaagaggagggc ttttttctccttgatgagatttctttagctgatgattctgtactagagcgacttaacagt gttcttgaagctgaaaagacattggtacttgctgaaaaaggtggacgagatgatgaagag aatgaggtagaactattagttgcaggaaagaaatttcgtatccttgcgaccatgaaccca ggaggtgactttgggaaaaaagagctttctcctgcattgcgcaacagatttacagaaata tggtgtccacaaagcaatggccgtgatgatttgatacagattgtaaaacacaatcttcat ccaggattgtctttgggtggaataaaccatcaaggggcagacatagcagagctcatgatg gactttgtcgaatggctgactaatcaagagtttggtcgccagtgtattctcagtgtgcga gatgtcttgtcatgggttaattttatgaatgtcatggtagaggatgaagagtcaaattct gccaaggaatatagccttctttacatttctccaatgatgtcttttatccatgctgcatgt ttgatatacattgatggaataggatcaggtacaacatcctgctcagctgatacagcttta ttagctcgtgaaaaatgcctggcattcttatgtgagaaaatgagtcaatttcttgagctg actgactctcagaagaatgaactaaagatttatgacagaacaaaggagaaggagtttgtg tggagggacaactttatgggaatccaccccttttttattccaagaggacctgttctccag aggaacagcattacagattatgctctaaatgcggggactaccgcactgaatgcacaaaga ctgttgagagccctacagcttaacaaacctattttgctggaggggtcaccaggagtgggc aagaccagtctagtcgctgccctggcaaaagcctcaggaaactgtcttgttcgaatcaac ctgtctgaacaaacggatgtgacagacttgtttggtacggacttgcctgttgaaggtggg aagggaggggaatttgcctggcgtgatggaccattactagcggcattaaaagctggacac tggattgtattggatgagttgaatctggcttctcagtctgtactagaggggctaaatgca tgctttgaccacagagcagagatttatgttccagaattgggaatgaattttcacgtacag cacaagatgactaagatttttggatgccagaatccgtacagacaaggaggtggaagaaag ggtctgcccaagtcctttcttaatagatttacacaggtgtatgttgatccactgtcagca gaagatatggagtttattgggaatacactgtttcctgctattgataaaattattattgct aaaatggttgctttcaataacaagattgacaaagaagtaatggctgaaaaaaagtgggga cagaaaggaggaccctgggagttcaacttacgtgatcttttccgctggtgccagcttatg cttgttgaccagtcaccaggatgttatgaaccaggccagcatgtatttttggtgtacgga gaaagaatgagaaccagggaagacaaagaaaaggttatatctatatttagagacattttt ggccaggaggctgatgtgtatacaggaaccagagagtttcacatcactccctataatgtt caggttggttattcagttctttctcgtggcaactgtattcctcatcctggcagaaatctt tcacttctgcatcactcgctgcaatccctggagtccataatgaaatgcgtgcacatgagc tggatggtaatcctggtaggcccagcagctgttggcaaaaccagtcttgttgagctgctg gcccatctgactggccatcgactaaaaatcatggcaatgaacagtgcgatggatacaact gaactcctgggtggatttgaacaggttgatatcaacaggccatggcagcgcctgttggaa aaagtggagaatgctgtgagcacactagtaagggacagtcttctcctgacagaaatttgt gcagatgatgccgaacttgtgctgcgtgcttggagcaatttcatcctgaattacaagccc aaatctctgggtgaaggaggtgggagtgttacagctgaattagtgagcaaactggaggga atacttgtacttacccagcgactaaacaacaaaataaattcttactcaaaggcagagttt gctctcctggtagaagagtttcggcgtttcaagctgcagcaggcccaggctgctgactgt atcagccacggcacttttgagtgggtggatgggatgttggttcaggcgctgcagtctgga gactggctgttgatggacaatgttaacttctgcaacccttctgtgctggaccgcttgaat gctttactcgaaccaggaggcgttcttaccatgagtgagagaggtgtgatagatggcaca attcctacagtagctccgcatccaaacttcaggcttttcctttccatggatcctgttcat ggggaaatatccagagccatgcggaatcgtgggattgaaatttacattcctggggagaac gatggaaatgtattggacaatctggatttgaagttactcctgcatggtgtgggtttagtg ggagatagcatctgtgatgcgcttatggctgtgcattcagaaaccaaggcagcaatagca ggttctgtgtcatctttgtcgcctttgcttcaggctgctgtgttaattgtgcagcagcta caaagaggccttgggttagcaaagtctttttacagagcctgttgggaagtctatggccgc tcacaacaactgcagattaaccaaaagcttgtgttagaattggttacgaagcatgcttca tctctggcttcccatgaaacttggggtgactcgttgctagcagcgggattgtggccagac tccctacctacaggtctgtttgcagctgaagactcgcttctttcgacagtccggagtgat gcacaggtcctaatgtattgtctgaataggctaaaccttaaaaactgcaggacactacct ctgactctgcaggatcttcaaacaattatgcagtccactaatcctgagagcctcaaattc agtgctgttgagatagatgcagactggatggataacatggaagttctccaggcttcagtg aaattgttcatagaaaaggcaaccaaccaagactggacactgagagttaaatggcttaac tccatagctaaaagtctgccacaggtgcttgatccggtgcggattcagctggaagcaggt gctgtagcccttggtagtttttatgccagtcccctctcctctggagtcagtaacatgatc aagttgctacagccaactatgacagatgaacatgtgatgtctctggacccaagatggaat atgcagtttttggatataattagaaattcaatgaactttgatacagaaatggaacacaca gatcaacttctaatccttttgaagtctgtagcaaatcgcgcagtattatttcttgaccga gaaaaaagaagctacactgagaagaatttgattaccagcaagaagccaagaaacagtgtc ttaagaatgtctctagatttccgcaaagatccaggaagttacagctgccttcctcataca attgtggtcaaccttgctgctttctttgaactctgggatgcgtttgcatttcactgggtg aagtctactcaggtggccttaagtgatgatgacatgcatgatattttatactgcttgctg tggcgtgaccggttctgggcagtctctgacactctgacagtggattcaccagggttgtca cttctgtctctgcactggcactgggttatgaagcatctaattgacagaattcctcagatg cttattggatcagaccaacacaaggtttccaaggacattcaatctgtttcacagcagatt cagagctgcttgtccaatcctgctggtatttctgccaatatgaaaatgttacagaagtct ctaggaagacctcttccctttaaggataaactgggcatggaatgtttttcccagttaaaa gttctcagcaaaccatttaacatcttggagctaagattggcctttggagaaagtagatgg caggaaaaaatatgctgtctgaaaatcgctgccactggatggaagatgaagaaagcattg ctgcaagctgatggcctgataattagagccaatcatacagatgatgttaatctgggtcaa ctaaagatttttttgaaagctgtacattcacagctgagagcagaaggagttgtgtatagt cattcagaagaaaggtttgctgaagataccgtctccagccagttagaccctgccttctta aaccaactctgcagtcgggttcagctgtggcctgcaatggagcacataggcacgctctgg cagtacaaactgacagcagattatgtggccaaggcttgtgcaagaagggggaacttcagt gaagagctaagcatgtgttcagatctagttcagcttctagctttttctctgaagttgaca ccagctgcttctcaccagctatctggactgtggcacttgttacaccttaatgaaataccc cctgaagaaatgtcccttctgtcatctcaactaattaatgctgcattagcatccttctgg agcagtactttcaccacagacccagactactggttgacttggaggccactacctataaca gaggaagagaacttttctaaatcacatattaactcttctatgaagggcccaggtgttttg acccgagccgttttctcaaagtgcttctttgaaattctaactagcagcagcaagacaagc cagtgggatgtgagtgggcttcctgttctgtcatcatcccatgtgacactgggagaatgg atggagagggcacagcagcttcacgaagtcaccacagcactgtggaccaacctggctgtc tcttcaatagcagattttagacacacagatgctagactacaaggaataatgctaagcaga cagctctctgccttggtagatttggttccagtggatcttcaagaagagtttttggagtgc tgtgagaagctctacctcaaggatcctgttgcatatgagtaccttctcaagatacttaga tgcatcactgatcaggagttacttcctaaagaattcctgtttctcctgctcacttgcttg cagcagttctttggggaagggcttaaggagttaccagagacagcttggcgaggaagcctc tgggtgaatattggtttggtgcagattcaggtgtggcttccacagaccaggtttgatccg gctgttaaaagagaatacaagctcaagtatgcaaaagaagagttataccagctggagtgt gaatggaaaacaaatgatttctcattccagctgcatactggaaaaagtatagaagatgaa gcggtcagcagctgtattcatccccatctcagactgttgcatgaaagaatgcagagattg aaggaacaaataagcagtctttccagaaaaaaggccttcaggcctccagctccaccctat gattgcttataccaggaggcttaccagtacatcaacagcatagcacgggtttcttcagtc caagatcttttagcccgccttctacagttcctccatggggaaagacctaaatcactccag gcaatacaaaacctgttaaatgaagaagcatcttggcagcaatcacaccatcagtttaga aaacacctggcagaggagtatgctgtattccctgatgccatcattccactgcaagctgca atcttacagctgcaacatggcatgcgattagtggcttctgaagtttatgcagtgctcaga agttttgtgcatccagctgatctcaccaacctcctcacttctctgttgacatttccttcg gttggccataccttccccacttacttagctcgtgcagaaattttatgctcagtgaattca gttgaggtccttcatggacttaaaaggttttctctgaagcactctgaaggagaatctgag ggagcagagcagacttgcccaactctggaacagctcctagtgaatgctttgttgcatctt cgatgccatgtactgtctagaggagaaatggaccagaaatctctgcagctttttagacat ctgtgtcaggcaattataaatgaatgggatgaacaggaacgccgtgcccgggagcgggag gcaatggaacgcagtctgtacagatacagaagtaaaagtcatgggaaaggacggagtgaa gaagagcaggaagaagaagaatttaggagaagatttccttttcatgaaaaggacttcgaa gatatcacagcccagccaagcctagaagaaaaaatggaaactgaagaaccatcagaagac cagctggaaattgatagagcccttttgtccaagagctctatgcaaacagtgatgatggtt catcaacagttgtgtttaaactttgctcgatccctgtggtatcaacggagtttgcctgct catcaggccaaacattatttcagtacatttatttcctgctatcagactggtgcatgcctg gtgtcgcaattttatcctttaattggtgctgaaatgaatgataatcttttgggaagccaa cttttagttagcactcttcttcacaataccttttttgaggaattaacttcagatcttctg ctgcagcaagatggcccatatgacttctaccagcatcctaatattcagcaagtcagacag tgccaacctgtacttgatagttttgctaaagaagtaaatgggctactgcaggaatggcca gaacatccagttcttgtgcagctgttagttgtaatggacagaatccggagttttccactc tctagtcctctctcaaagttcctgaatggcttggaaattcttcttgcaaaggcacaggac tgggaggaaaatgctagtcgagctttgtccttgcgaaaacatcttgatttggtcacacaa ctgattattcagtggcgtagactggagttgaattgctggtcagtaagtttggacaatatt atgaaacagcatgtagagaaatccacaaagcactggttctcaatctatcagatggttgag aagtatgttcaagaacagacaggggtaaacacagaagacactgagccaatggatctgaaa acgctggtcagcacattacaagctttcatcgaaggatccacactgggagagtttcatgca cgacttcaggcactactggttttccactgccatgttttgctgatgcctcaagtagccgaa aaggacattctgtgcagcatcctatggaatctatacaattattataagcagttttcagag tgtattgagaccagaatcactgaacttcgccagcctatagaaaaggaacttaaggaattt gtgaagatttccaagtggaatgacgtcagcttctgggctataaaacaatcagttgaaaaa atacgcaggaccctctttaaattcatgaagaagtttgaagttgttctggatgagccatgt cagcctgccttggtggaaattggtaaagaagagcagctggactgcttgcaaaagcaagaa gaatctgagaacagagagaccaaagttcagagattgaacaacacattaagaaaaattctg tctgctagaacagatgttgccaagagggcactcccagaagaatgccaggatggcattaca tttcatacagaatctcttcagtatcgtctgcctaagcttactaaaaaaatgaagaaaatg tgtacaacagttacagaaaataattcgttcttgaatctggtggaaaatcttgacgagttc acaggtggtatcattgtttctgtagttgaactgcaaaatttaacatttgatcagacagca gataaggagaagcagaagtcagaggcaaagcatattcagatgcagaagcaacgggctttg tcagatctctttaaaagccttgcaaaaacaggtttgtcataccggaaaggtctgtcttgg tcccgttcaaaagactatcatgaaattctctacctacatccactggacctgcgtagtgca ttaggtgtagtaaatcgtacgcatgatctggatgccacattgttgacagaggtttcttct gcctgggatggatgccagaagtacttctatcagtcgcttgcacgccactccagacttcag acagcattattagcaccttccaaggatattggactaggtagcattgaacgatgcaaagga ttcactgcacacctcatgcaggtgcttgtcagacagagacaatctcttgctgcattgaca gaacagtggatcttactgaggaaccttctgagttgtatacaagagatagattctaggctg actgctgacagagaatatcatgtagcatttcctcctcaagacagtatgcaatgctggact gacaaactgcagcaactttccatgcagtgtgtgatggttctcgaggagctgtcttggttt atgcagtgctgcccaaaagaagagttaacaaagtgcagtgacaatgaaaggacagatgtc aaaacaaacaattttcagagttcaggacctgaaatggggaatgtttttacgggaatacct gacctaattccctcagagctaaaatacctcactccagtaacaattgagcaactgcctcct ggatgcaggatgcgaaataaggatcagttatggctgcaggtagctgcacagttgactgcg atgctggcaaatgtgaaggcagtgaaagcagaagtggacaaaataagacaacagtcacgt gagaccttgttttattcctggagagattttgaagtttgcatatcagctatggattgtttg ctggaagtctcagctcagttacaaggactagagtccctgtttcttccaaatggagaaggc acacaagctgcaaatcagatgaccctaatcaagagcctaaagtatatacaagaagtagtt aataatacatctgcagacttcctagcctggagaacacagctgcttgcttccatgtcagat tgcagtggaaatcaacagacagatgaagagtttgtggagcacttctcggcaaaagtggaa actgttatccgtgttgttctgtatgccatccagtgtttggtagagagaaaacaggaagat ggaaaagaggaagaaaagtctacagaggaaaatgaggatgcagcctcatttgacgtgatt aaagcaggacatataactaagcttttggatgaagatctctctgctgatttggattctttg aatgtgcagaaagtgattttagcagtttcagaactcctggagaacctgaaatcttacaga ggagattatacttcagataaacataagttcttcaaccagtcctgctatttgctggtgcgt ctaaagcccctgctctgcaagtattcagacctcatcctgttctacctcactgtttcgctg gcatctcacaggagtactggaaaattgctttctgttctaactagcatttttacagagctt gcccaaaaggggttttgtctgccaaaagaattacttgaagatgaagctggagagggagca acacagtttcatgattatgaggatggtggtattggagatggagaaggcaagaaggatgtg agcgacaaaatagaaagtgaagatcagatagaagacagttttcagaagggtgaagagaag gagaaagaggatcaagattctaaaccagacattgaaggagaagataatgcaattgaaatg tcagaagactttgaaggaaaaatgcatgatggagaacaggaaaaaaaagaaaatgatgac agttcagatgaagaggagctggataagcagatgggaaatcttgataatgctgaagctgat gataaactggatgagaggctctggggggatgaagatgatgatgatgatgaagatgatgcc agtagcaaaccagaagaaactggaccaggaatggatgaggaggattcagagctcgttgca aaagatgacaattcgggcacaggaaacaaggataataaaaaacagcctcccaaggatgag gaaaaagagcaacaagatgatgacagtgaaaacaaagagaaaattcatgaacaaattgat gagcgtgagtatgatgagaatgaagtagatccttatcatggccaacaagaaaagcagact gaagttgaacctttggaccttcctgataatttgaatctggagaatgatgaaaagagtgat gaggaggaagaggataaagaagaagagaatgcttttgaggtagatgagaaacctgttgat ttaactgaggcagagaagacagaagaccagaatcaagaggatactggtgagacagaaagg gatgatcaagatgcagaaccagctgaagaaggcatttctgaagagaaggaagatgaaggg gacaaagatggtgatgaacaagaagaaaacgcagggaacactgaggatgaaacagaaaag gagaaggaagagtcacaaccacctgatgaagaaaaaaatgaatctgctgaagataaggga atccctgctgctgaccaaggccttcaacctcgggaagaagagggtaaagataattcagag atggatgaacagattcctgagcctgaggaaagaatggaacatgaaacagaagggcagact gggcaagaaaatctgcagagtgacagtgctgttgagctggctggagaggcttcagaaaga gaccagtctaaagaggaatacggaagtggagcttcaagtgcaaatcagtcggaaggccat gaatccacacgcatggcccggatggcttctcagaagcaaagcagaaaaaatacccagagt ttcaagaggaaacctggacaggcagacaatgagcgctcgatgggagatcacaacgaacat atccacaagcgactgcgaaccatagaatccagcagtgaagcaaagcacaacacaaatcag cctaaacaaaacgtggaggaggctgatgcatttgaacacattaaacaaggctctgaattc tatgatgcacaaacatatgatgtagctagcaaggaacaagagaaacctattatgcctctt gaagaaaaggaagaggcagattctgaagatgcagctatggaagcagaaatgcagaacaat gaggatctccgagcagtagacacagaggagctgaagccagaaaaaaagaattctactgcc actaaaactcctggaccaggtgacgtagagccagagatccagactttcgactctgaggat gtcaatgactctacaacagaaaagctaccaaaggtgactgaagagaagccagagagaagc aaggactcaaccatacatacagcccatcagtttctgatggacactccccagcacatcgtt agagatcctgaagagctaagaaaggaactggaaaggcaattggaagcttggcacacacag cagtctggaactccagatgaggagaaggaagcagcacagttgtggcagaggtatttggta ctgacagctcctctgtcacagcagctttgtgaacagctacgactcatactggaacccact caggcagccaaattaaagggagactacagaacagggaagagactgaacatgcgcaaagtg attccatatattgccagtcagttcagaaaagataagatctggttgcgaagaaccaagccc agtaaacgacagtaccagatttgcttggctattgatgattcctctagtatgatagacaat cattctaaacagcttgcatatgaatccctggcagttattggaaatgcactgactcttcta gaagtgggacaaatcgctgtgtgtagctttggagagactgttcagctgctgcacccattc cacgaacagttcagtgaccagtcagggacacggatattgcgtctttgcaaatttcagcag aagaaaacaaaaatagcccagtttctagaatcatcagcaaatatgtttgctgcagcacag cagttgtctcaaaatattaatccagaaacagcgcagctgcttttgattgtatctgatgga agaggtcttttcttggaaggcaaggaaagagtgaccgcagcagttcaagcagctcagaat gccaatatctttgttatttttgtagtgttggacaatcctaattcccgggattccattttg gacattaaagtacctatattcaaaggacctggagaattgcctgaaatcagatcttacatg gaagaattcccattcccattctacatgatccttagagacgtgaacgcgcttccagaaact ctcagtgatgcactcagacagtggtttgaactggtgactgcctcagacactttgtag

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