Thiomicrospira aerophila: THIAE_08530
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Entry
THIAE_08530 CDS
T03589
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tao
Thiomicrospira aerophila
Pathway
tao00300
Lysine biosynthesis
tao00550
Peptidoglycan biosynthesis
tao01100
Metabolic pathways
tao01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tao00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
THIAE_08530
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
THIAE_08530
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
THIAE_08530
Enzymes [BR:
tao01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
THIAE_08530
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NNH6
Motif
Other DBs
NCBI-ProteinID:
AHF01794
UniProt:
W0DXT6
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Position
complement(1715898..1717355)
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AA seq
485 aa
AA seq
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MTTDKGRTVMRFGRWTLGQLAEWLNVILPTKWQAQADLAVAQMVTDSRAVMPGDVYIAIE
GTRFDGHRFIAQAIEQGAVACIISNKNYAKQTVPCLLVSDTTRALGRLGQAHRQAAQLEC
LVAVTGSNGKTTVKELLAALFATKGPTLATQGNLNNQFGVPRTLLRLRDEHRYAVIEMGA
NHQGEIDCLTRLAEPDIAIITLAAPAHLEGFGSLDGIITAKGEIMHGLKPDGVGIINTDS
PGFSHWFGKLTRSGRKAMSFGQAAQADIRIRNVSTTKQGIQFELYYQQAWRTVTSPLLGV
HNAYNLAAGAAVAQVLNWDWDDIAPVFAKFTGTDGRLQIFQLGQLTLIDDSYNANPSSMA
AGLDSLHALASPDNKPMLACLGSMAELGSTAAEAHYQIGRQAVKLGVRQLWAQGGNADDY
VAGFKSLASGKTLAQAAEHAAMIEHLFTLYQTGEPWVVLIKGSRSAAMDQLRPGLTQRIA
DAHLS
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgacaactgacaaagggcggactgtaatgcgatttggacgctggacgctgggacagcta
gcagaatggttaaatgtgattctacccactaaatggcaagcgcaagctgatttagcggtt
gctcagatggtcacggattcacgcgcggtcatgccaggtgatgtctatattgcgattgaa
gggacgcgatttgatggtcatcgatttatcgcccaagcgattgagcagggtgctgtggcc
tgcatcattagcaataaaaactatgctaaacaaactgtgccttgtttattagtgtcggat
accacccgcgcgttgggacggttggggcaggcccaccgacaagccgcacagcttgaatgt
ttagtggcggtgactggttcgaacggtaaaacgaccgttaaagaactgcttgctgctcta
ttcgcgactaaggggccaacacttgcaacacaaggcaatctaaataatcaatttggtgtg
ccacgcacattattacgtttgcgtgatgagcaccggtatgcagtgattgaaatgggcgcg
aaccatcaaggcgaaattgattgtttaacccgcttagctgaaccggatattgcgattatt
acccttgctgccccggctcatcttgaaggttttggcagtcttgatggcattattaccgct
aaaggcgaaattatgcatggcttaaagcctgatggcgttggcatcattaatactgattcg
cccggttttagccactggtttggtaaattgacccgaagtggtcgtaaagcgatgagtttt
ggccaggctgcacaagctgacattcggattcgaaatgtgtccaccaccaagcaaggcatt
cagtttgagctgtattatcagcaggcctggcgcaccgtcactagcccgttactaggggtt
cacaacgcctacaatcttgcggcaggcgcagcggtggcacaggtgttaaattgggattgg
gatgacattgcaccggtgtttgccaagtttacgggtacagatggtcggttgcagattttt
cagctgggtcaactcaccttaattgatgatagttacaacgctaatccaagctcgatggcg
gcagggttagatagtctacatgcgcttgccagtccggataacaagccgatgctggcctgc
ttaggatctatggcagagttaggcagtaccgctgctgaggcccattatcaaattggtcgg
caggcggttaaattaggtgtgcgccaactctgggcacagggtggcaatgccgacgattat
gtcgcgggctttaagtcgttagcaagcggtaaaaccttggcccaagccgccgaacacgcg
gcgatgattgaacacttatttaccctttatcaaactggcgaaccctgggtcgtcttaatt
aaaggctcgcgcagtgccgcaatggatcagttgcgccctggcctaactcaaaggattgcc
gatgctcatttatcttag
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