Thermus brockianus: A0O31_02102
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Entry
A0O31_02102 CDS
T04600
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tbc
Thermus brockianus
Pathway
tbc00300
Lysine biosynthesis
tbc00550
Peptidoglycan biosynthesis
tbc01100
Metabolic pathways
tbc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tbc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A0O31_02102
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A0O31_02102
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A0O31_02102
Enzymes [BR:
tbc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A0O31_02102
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
APD10158
UniProt:
A0A1J0LUV6
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Position
complement(1903125..1904327)
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AA seq
400 aa
AA seq
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MRDLHWDSREVTPLSLFVALPGTRTHGRTFIPEARAKGANLVLADVPGEATVEVEDPGQG
LVRLGKALRRLFPGVVVAVGGSSGKTTTKEALAQGLGFPAPFGNQNTAPPLTRFFFHLDP
RAEGAVVELGVDRVGEMAELMALSEPALSVLTALGEEHLQAFGSLRGVVEEEAKLLDAPQ
ALVSLRAKEVLLAFGRYKGEPTYGFGEATFQGRELELLPERTRFRYRHLRVEVPYPGLGP
ALGALAALAVAELLGKDLEGVAERLAGLRLPPGRMERRVLGGVVFLNDAYNANPLSVKAG
LAWLAAQPGRKWVVLGEMRELGALAEPLHLEVAEEAARLGLRPLYLGPYAKAQAALGGEA
AETLEEAMAWLKARVAPGDLVYLKASRAVGLERILELWDA
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
gtgcgggacctccactgggatagccgggaggtgacccccttaagcctcttcgtggccctt
cccggaacccggacccacgggcgcaccttcatccccgaggcccgggccaagggggcaaac
ctcgtcctggcggacgtccctggcgaggccacggtggaggtggaagaccctggccagggg
ctagtccgcctgggcaaggccctgaggcggcttttccccggggtcgtggtggcggtgggc
ggaagctccggcaagaccaccaccaaggaggccctggcccagggcctgggttttcccgcc
cccttcggcaaccagaacaccgctccccctctcacccgcttctttttccacctggacccc
agggcggaaggggcggtggtggagcttggggtagaccgggtgggggagatggcggagctc
atggccctttccgagcccgccctttccgtcctcaccgccttgggggaggagcacctccag
gccttcgggagccttaggggcgtggtggaggaagaggccaagctcttggatgccccacag
gccctggtgagcctccgggccaaggaggtgctcctggccttcggccgttataagggggag
cccacctacggcttcggggaggctaccttccaaggaagggagttggaacttctgcccgaa
aggacgcgcttccgctaccgccacctccgggtggaggtcccctatcccggcctcggcccc
gccttaggggccctggccgccttggcggtggcggagctcctgggaaaggacctggaaggg
gtggcggaaaggcttgccggcctacgcctacccccggggcgcatggagcggcgggtcctg
ggaggggtggtcttcctgaacgatgcctacaacgccaaccccctctccgtaaaggccggc
ctcgcctggcttgccgcccaacctggccggaagtgggtggtcctaggggagatgcgggag
cttggggccctggcggagcccctccacctagaggtggcggaggaagcggcccggcttggg
ctaaggcccctctacctgggcccctacgccaaggcccaggccgccctcgggggcgaggcg
gcggaaacgctggaagaggccatggcctggctcaaggcccgcgtggccccgggggatctc
gtttacctgaaggcctcgagggccgtgggcctggaaaggatcctggagctatgggacgcc
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