Thiobacillus denitrificans: Tbd_0115
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Entry
Tbd_0115 CDS
T00275
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tbd
Thiobacillus denitrificans
Pathway
tbd00300
Lysine biosynthesis
tbd00550
Peptidoglycan biosynthesis
tbd01100
Metabolic pathways
tbd01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tbd00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tbd_0115
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tbd_0115
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tbd_0115
Enzymes [BR:
tbd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tbd_0115
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AAZ96068
UniProt:
Q3SMH7
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All DBs
Position
122241..123635
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AA seq
464 aa
AA seq
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MSEGNCMMRLSEAAAMLGVPLPGADAEVVRVTTDSRTLRPGDLFVALRGERFDGGAFAAQ
ALQQGAAGVVLDRAQAPDLAQALRVDDTRLALGRLAQAWRQRFAIPLVAITGSNGKTTVK
EMLAAILRVEAGDAAAVLHTEGNLNNDIGVPLMLLRLRDHHQYAVLEMGMNHAGEIDYLT
RLARPDIAIVNNALTAHIGFLGSVENIARAKGEIFNGLTDAGIAVFNADDPHAGLWREAN
RQRCVVDFGLVHATSVRGDYRADEFGSALTVTLPNATLDIALQVPGEHNVMNALAAVAGA
FALDVSHRSVVAGLAGFGGVKGRLQRKAALHGSTVIDDTYNANPDSVKAALAVLAQQPGK
KIFVLGDMGELGDDAASMHEEIGVAARAAGVGRLLALGDLSCATVAAFGTGAMHFERIEE
LLAELENELAPGTVVLVKGSRFMQMERVVKSFTEASDAPGMQEH
NT seq
1395 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaggggaactgcatgatgcgtctgtcggaggccgcggccatgctcggcgtgccg
ctgcccggcgccgacgccgaagtcgtgcgggtcacgaccgacagccgtacgctgcgtccc
ggcgacctcttcgtcgcactgcgcggcgagcgcttcgacggcggcgctttcgcggcgcag
gccctgcagcagggcgcggccggcgtggtcctcgaccgggcgcaggcgcccgacctcgcg
caggcgctgcgcgtcgacgatacccggctcgcactcggccggctggcgcaggcgtggcgg
cagcgttttgcgattccgctcgtcgcgatcaccggcagcaacggcaagacgaccgtgaag
gaaatgctcgcggcgatcctgcgcgtcgaagcgggcgacgccgcggccgtactgcacacc
gagggcaatctcaacaacgatatcggcgtaccgctgatgctgctgcgcctgcgcgaccac
catcagtacgccgtgctcgaaatgggcatgaaccacgccggcgagatcgactacctcacg
cgtcttgcgcgacccgacatcgcgatcgtcaacaacgcgcttactgcgcatatcgggttt
ctcggttcggtggaaaacatcgcgcgcgccaagggcgagattttcaacggcctcaccgac
gcgggaatcgccgtgttcaacgccgacgatccgcatgccggactttggcgcgaggcgaat
cgccagcgctgcgtcgtcgatttcggcctcgtgcacgcgaccagcgtccgcggtgactac
cgtgccgacgaattcggctcggcgctcacggtcacgctgccgaacgccacgctcgacatc
gcgctccaggttccgggcgagcacaacgtcatgaacgcgctcgcggcggtcgccggcgcg
ttcgccctcgacgtctcgcatcgcagtgtcgtcgccgggctcgcgggcttcggtggcgtc
aagggccggctgcagcgcaaagccgcgctgcacggcagcaccgtgatcgacgacacctat
aacgccaacccggactcggtcaaggccgcgctggccgtgctcgcgcagcagccgggcaaa
aaaatattcgtgctcggcgacatgggcgaactcggcgacgacgccgcgtccatgcatgag
gagatcggcgtcgccgcgcgggcggccggcgtcggccggttgctcgcgctcggcgacctg
agttgcgcgacggtcgcggcgttcggcacgggcgcgatgcatttcgagcggatcgaggaa
ctcctcgccgaactcgaaaacgaattagcgcccggcacggttgtgctggtaaaggggtcg
cgcttcatgcagatggagcgcgtggtcaagagtttcacggaagcgtccgacgcgccgggg
atgcaggaacactga
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