Treponema brennaborense: Trebr_0949
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Entry
Trebr_0949 CDS
T01489
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tbe
Treponema brennaborense
Pathway
tbe00300
Lysine biosynthesis
tbe00550
Peptidoglycan biosynthesis
tbe01100
Metabolic pathways
tbe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tbe00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Trebr_0949
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Trebr_0949
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Trebr_0949
Enzymes [BR:
tbe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Trebr_0949
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEE16385
UniProt:
F4LJJ0
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Position
1145836..1147302
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AA seq
488 aa
AA seq
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MSIESAAATRTSESSLLSFRETIEAVAGKYVCLAGAAERFHFTNVTTDSRTVTDGSLFVP
LVGETQDGHKYILQALEQGARVVFADLESYECLAGLFMDFLENYPDAVFIVVKNTLTALQ
CAAAAYVKKFPDLIKIGITGSSGKTTTKELIAAVLSRKYTVVMNEGNLNSETGLPLSVFK
IRAEHEVGIFEMGMNRKGEIAELANVLCPRFAVVTNIGSAHIGILGSKDAIAYEKKQIFS
RFTADCVAFIPAADPYADFLAENCGGTVVRYGVNTDPVSRIKNAGLAGTEFLYRQVPILL
PLPGAGNFSDALAAASLASYMGFGADDIKAGLESVRPLFGRSQIIGGPVSVVQDCYNANP
DSMEQALDFFASLDIEPGRKIAVLGDMLELGAESESAHVAAVRSAAASGAVLLVCIGRAV
SAAAERLVREDRVGSVRVECFADSSDAVISDAAALLCGFLRRGDVVLLKGSRGMRLERLT
PYLTECAV
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgagtatagaatcagcggcggcaacgcgtacatcggaatcttctctgctttcttttagg
gaaacgatagaagctgtcgccggaaaatatgtgtgtctggcgggtgctgcggaacgtttt
cactttacgaacgtaacgaccgacagcagaaccgttacggacggctcgctgttcgtaccg
ctggtgggcgaaacgcaggacggacacaagtatattcttcaggcgctcgaacagggtgcg
cgagtcgtttttgccgatctggaaagttacgaatgtttggccggtctgtttatggatttt
ttggaaaattatcccgatgcggtttttatcgtcgtaaagaacacgctgaccgcgctccag
tgtgccgccgccgcgtatgtaaaaaaattccccgatttgattaagatcgggataaccggt
tccagcggaaaaacgacgacaaaggaattgattgccgccgttctttcgcggaaatatacg
gtcgtcatgaacgaaggcaatctgaattcggaaacgggattgccgttgtccgtcttcaag
attcgggcggaacacgaagtcggcatttttgaaatgggcatgaaccgcaagggtgaaata
gcggaattggcgaacgtgctttgtcctcggttcgcagtcgtaacgaacatcggttctgcc
cacatcggaattctcggcagtaaagacgcgatagcgtatgaaaaaaaacagattttttcc
cgttttaccgccgactgcgttgcgttcattccggcagccgatccgtacgccgattttctt
gcggaaaactgcggcggcacggtcgttcggtacggggtgaatacggatcctgtttcccgg
ataaaaaacgcgggccttgccgggacggaatttttatatcggcaagtcccgatcctgctt
ccgcttcccggtgcgggaaatttttccgatgcactcgcagcggcgtcgctcgcctcgtat
atggggttcggtgcggacgatataaaagcgggactggaatccgttcggccgctgttcgga
cgcagccagatcatcggcggaccggtgtcagtcgttcaggattgttacaacgcgaatccg
gactcgatggaacaggcgcttgatttttttgcatcgttggatatcgaacccggcagaaaa
attgccgtactgggcgatatgctggaattgggtgcggagtcggagtccgcgcacgtcgcc
gcggtacgatccgccgcggcttccggtgcggttttactggtgtgcatcgggagggccgta
agtgcggccgcggaacggctcgtacgggaagaccgtgtcggttccgtacgtgttgaatgt
tttgcagatagttccgacgcggtgatttccgacgcggccgcgctgctgtgcggtttttta
cggcgcggcgacgtggtgctgctcaagggctcccgcggtatgcggctggaacggctgact
ccttatctgacggagtgtgccgtatga
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