Trematomus bernacchii (emerald rockcod): 117488945 Help Entry 117488945         CDS       T09643                                  Symbol obscnb Name (RefSeq) obscurin   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism tben  Trematomus bernacchii (emerald rockcod) Pathway tben04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:tben00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     117488945 (obscnb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tben01001]     117488945 (obscnb)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:tben04131]     117488945 (obscnb) Enzymes [BR:tben01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      117488945 (obscnb) Protein kinases [BR:tben01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    117488945 (obscnb) Membrane trafficking [BR:tben04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     117488945 (obscnb) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Ig_5 Ig_6 Ig_4 Izumo-Ig V-set_CD47 SOS1_NGEF_PH fn3 C1-set RhoGEF C2-set_2 Ig_DSCAM-DSCAML_C PH Pur_ac_phosph_N IQ Ig_CD22 SH3_2 RHG20_PH Motif Other DBs NCBI-GeneID:  117488945 NCBI-ProteinID:  XP_033994026 LinkDB All DBs Position Unknown AA seq 6633 aa AA seqDB search MDQNLFGGVPRFLTRPKACSVCVGKDATLSCTIVGSPTPLISWEKDKLKLTSGGRFKTVE DGNLYRLTIYDLTLEDNGQFMCRAKNTVGEAYAAVTLKVALQTEMAQRAPVFMVKPTSTR VCLGGDVVFHCRVAAHPDPNFDWEKDGRYLGESNRIKIVSDTDSSTLNIQSVRNLDSGTY TCRAQNTVGRSHSAAALVVDAQDSLHLSADKNTSSLLSHLQKRKEEMKKDISIYRTEESR SSGSSSTKTSITDSLSSLSQEHELRASALAKLPKGVFTRTCTVTEGKHAKLSCFVTGHPK PHIIWRKDGSNISEGRRHVIYEDQAENFILKVLYCKQTDNGLYTCNATNMAGQTYSAVLV TVKEPKVPFRRKLQDVEVQEKTSATLLCEVPVSATQASWFMEETKLDQSTKYYMEQEGTL LRLTIHNVTTNDDGVYICEMKEGSRTVAELTVLGNITKKLPRRTVVPVSDTVIFCVELER PFPDVYWTRNGVKLKGDSRIAIACVLRQYTLTIRDCQADDSGEVAFVAGDCKTSTRFSVT AARKHPPDPPVDAVVANKTDSSITIQWSPPDSDRPVPIKCYFVERRKVGTQTWQRCNSGE TILSTEITVCSFKEEATYQFRISAMNDFGQSDYLEVPGSFYLEPSAEIRKGLMNSTAFFS EEFSISVELSAVCSAFWSLNGRLLRSGGDYLITRIKNTHTLLIRNVTMEMNGTEVKFVGG GSQSSCILSVQAPVVRFTNKSNLQEVFCSAQATAQLTAEVSDYDAQVVWMRNGREVKTGK KYEYMIVDRKRILMVHNVTEEDVGIYECALADDKISLQLSLKDEPAKFLNKARGTMGMSS TLKGDLELTCEVSPASAAVVWKKDQVQITEDQRTTTVAKGTQRKLIIKNAKKSDEGHYSC ETAADKVTFQVKIKETQAVAAFSNRESVQKEVKATLTQKATLSCDVSDSKIEVKWYKDGK QLISSRTIYSEVKGSTRQLVIEKVEKSDAGEYTCEAAGDKLVFKISVSEFQSAFSNKESV QSEVKATLSQKATLSCEVADTKTEVKWYKEGKLLTSSKTIHTETKGKSRQLVIDSVEKKD AGEYICEAGTEKLAFKMHVAEAQSAFSNKESVQKEVKATLSQKSTLSCDVSDTKTEVKWY KEGKLLTSSKTIHTETKGKSRQLVIDSIEKKDAGEYICEAGTEKLVFKLNVADTQVQSAL SDKESVQKEVKASLSQAATLSWEISDSKSEVKWYKDGKLISTTQAIHAESKGKSRQLVID NVEKKDAGEYMCQAGSEKLVFKMHVEGSSTEVHAKSSFVNKESVQTELKATLSQKVTLSC EVADTKTEVKWYKDGKLLTTSKAVHMESKGKIRELVIEKMEKKDAGEYICEVGTEKLAIR VQLTEIQQKLAFSNKESVQSEVKATLSQKATLSCEVADTKTEVKWYKEGKLLTSSKTIHT ETKGKSRQLVIDSVEKKDAGEYICEAGTEKIAFKIQVAEAQSAFSNKESVQKEVKTTLSQ KSILSCDVSDTKTEVKWYKEGKLLTSSKTIHTETKGKSRQLVIDSVEKKDAGEYICEAGT EKIAFKIQVAEPPAGFSNTQSVKQEVKATLSQKATLSCEVDDTKTEVKWYKDGKLLTTSK AVHMESKGKIRELVIEKMEKKDAGEYTCEAGTEKLVFKMQVTDAAVKFQKKLVKDTCIVQ ASEKVVLTTELTTESGSVKWCRDGVELKEGSKYEMKKEGLSRTLIVKSSESKDSGTYSCQ TADDKLEFKVQVKDSALKFVVPLKPATVDLEGTLSLMCELNQASGDVVWQHDGREIKPGG RYCVRTDGAKRVLTVTGMTKEDEGEYSCECRNDKTSAKVTSKAPRLVRLTTKLNNVAAME GKDAIFKCAVNPADVNVKWFHNSIPVTAGPKYKIGRGGSSHSLTITSVTQKDGGEISVDA EGKSCKANLQVEHEPVTFKKMLENLTVEEQSEVKLELELSKVSDEVRWMKNSVVLQPSGN MEIQVNGAKQALIFKSVAYADRGIYSCETLDDKTQAKLSVEMKKIQVIKGLTETKSHETE TVTLEVELSQADVEGFWTRDGAKLKSGANCRITAFGKKHSLTLSNLKREDAGMIAFQAEG VHNSGTLVVTELPAMIAKPMVDISVADKEKVTFECEVSKTNADVKWFKDDVELKPGKNFG IHSLGRKRSLVINKCTPEDAGTYICRTTDDNTSAKLTVNAREVKIVKKLEDVEVMEKESA AFVCEVSHDEVECQWYKGSTKLKVGDNIKMRQEGKTYVLLFKSVTIEDMGEIKFTADKAS SAAKLKVKELPVKFVKKLRDKIAMYKHRGHLECQVSRASAKVKWFKNKTEIKHGKKYEIK SEDVYRKLTINDVASGDEDTYTCDATDEKTSCKLLVEEQCISIVRELTSVEVTEPFAAVF EVEISMELVKPPIWTLNAVAVKESADVEMEKEGTMHSLTFKKTKASMTGPVQFTAGKSKS LAQLTVKERPLEITEPIKDVKGKEKSSAILTCKFSASPKEVAWFKGQVPLTASDKYNMKQ DATRAQLTIQRLTEEDSGDYRCQSGPAEAKGTLTVEVREMKISKHLADTEVDEDNDAVFT CEINYADEEVQWLLNDKVLFTNEVNTIAHDGKVHKLTLKNLAPQDGGTITFQVRKVKESV TLKVKEKRAVFLKSLDDVIGEEKGMITLACEASKPRVSPVWRKEVKVLKAGSKYELLHTG KSLGLIIKDVTKEDAGEYSCDLGTEVSKAKVTVREIAIGITKWLKSAEVNEGDSCNFECI LSRESTDECSWTLNGNTITDGGRFKVTSKGRKYMLTIKDVTPADAGEVVLNIKDLNSKTT LKVEGKASSVSKGLQSVSAVQGEDAVFTCEVTKASSTVNWSMEGKAIKKSQKYDIRQEEK VMKLTIHNISAQDSGEYSCEVVGGATTKAKLEIKEPIHKFTKELKDSQAEEKSNVTLQCE TAQTPSTVVWLKGHTELNAGGRYEMSQKERVLTLTIKQLEEKDTDIYTCDVGTAKIMAKV TVNALPANFKEKLNNQGRKEGESVKLCCKLSKHADGVQWKKGSEVLKAGEKYEMKMEETS CELQIKNLEVEDSGEYSCLCGDQKTSATVKVTALPPTFKQKLESQEAEEGASVTLRCELS KPGVPVEWKKGTKVLKSGEKYQMKQEASVNKLLINKVLPEDSGDYSCVCGDLKTTASLNI KAQPVTFKQKLESQEAEEGASVTLRCELSKPGVPVEWKKGTKVLKSGEKYQMKQEASVNE LLINKVLPEDSGDYSCVCGDLKTTASLNIKAQPVTFKLRLESQEAEEGASVTLRCELSKP GVPVEWKKGTKVLKSGEKYQMKQEASVNELLINKVLPEDSGDYSCVCGDLKTTASLNIKA QPVTFKQKLESQEAEEGASVTLRCEISKPGVPVEWKKGTKVLKSGEKYQMKQEASVNELL ITKVLPEDSGDYSCVCGDLKTTASLNIKAQPVTFKLKLESQEAVEGASVTLRCEISKPGV PVEWKKGTKVLKSGEKYQMKQEASVNELLIIKVLTEDSGDYSCVCGDLKTTASLNIKAQP VTFKQKLESQEAEEGASVTLHCEISKPGVPVEWKKGTKVLKSGEKYQMKQEASVNELLIN KVLPEDSGDYSCVCGDLKTTASVKINAPPSASKPESKSQESKETIEAKAPEAPSKVAQDE RKKQEINETVEAVTLPRTGQTPQQQLLKVEVHKDSQELKVAGEVEKTAAGTAADTKRQGT KEPLEAQPVLFKTQLQNLIRQEGESASLRCKTTKPGASVVWRFGDRVLASSSKYHLKQEG TVVELVIYKLRGADSGEYSCDAGNQRTSAVLSVQEVEVTILKFLESCVVYQGDDVRFECR VSREEAPLAQWKLQDVPLQNNEMNLIKSEGCVHSLKLRGVTTADSGTVTFTVGNHTSTAS LTVKAAPATFKKELESQEAIEGDKASLSCETSSPDCKVTWLKDSTVLIHGEKYSLEQTAT THILVIHKLDVKDSGEYTCETGDKKSTATLTVKARVRITRELSDVTVTTGQDAVFEVELS HPGVTNSEWWLADNLLQNNDLNQMSSQGTVHRLTLKMVTTDESGDVAFVLGEEKTVACLL VEEKPKVLILEKPHNTSAVEGETVTLACTISDTKASVTWKRNNTAIQAGLKYDLKSNGAL HQLSINNLVPEDSGTYTCDTGDAQCDSTLTVQGTPVSFRKELKNHDAIEGDDVTLHCELS KPGVPVEWRKGGLVLKPGKQFEMKQEGCIQELCIRNVEPEDSGYYTCDAGDQLTTASLAV QAKEVSFVCGLKTTDVFVGEWATFSCQLSGRAPHKVQWWLDGTLLENSPFSEIGLSPGNI HTLTLKNLATDDSGTVTFEAGSLTSTAKLLVKDPTVEVVSELEDIRVLENQPAEFICQFS RPVKPQWKKDGQPLQPDGRRVVVEQDWNVARLYISHVSAEDRGTYSCEAEGTCAVASLFV EGKPIDIVQGLENVETFDGGEVLLECALSRPESKDCHWFLDGKPVKESPNAEIVTFESGR RHLLLLKELRVTDSCTVTFKVGTASTSAQLSVKRWQLDVVKSLEDKVAAVGEKVEFNVEL TEPVPSAEVAWYMNGVEIKPSDLWALRADGCSYRLVLRKAPLMPQQEITFAARDALSLAK LTIITVPDPPEDPEVLTKTERSVNLSWFTPLHDGGSPILGYRVEMRLVDSSLWLPCHSDP VFNTEFVVENLTAGSGYRFRVAATNRAGIGEPVEMPHTVQLEAPIQPAVCPGVEAKQTEA ETMGQPSLPPEAAEEGDVHELWEESAKKRRMSREPTLDSITEQPEEDGKGGKKKSEKVEI KSEEKELAIVSKTQVESKISTTSEDESVSGGSTLVSYLKKSSTSSVTATNERETLTTEKF FAHFKMEEQTVQESRVETTIIQQTDAKQVSTEETEIMEISKEDEPELRDAAIKIQAAFKG YKARKDMRPVFKDAFKDQTKEPNGTIHLECIAEGKPDKVRWLKDGEPLTDGKHHHIDIYN DGTCSLVITAITIKDTGVYTCEVTNKYGVTSHSGKVTVGTERESSGRRPLTVGYSADSEP DSSSGSEMDESLRQASKRLCRLLRSSLPPNVEEESFVSADEGDLGPPDPHSYREDDCYIY IRFDSRTEAEVASKRFQEMFTIHGVPVDTSILEAGPLKVELRIRKMGYMQDGAQTPTQER QPVAFMAGAQAAPVFLTELQSQDVPDGYPVSFDCVVIGKPPPSVRWYKDGKLLEENDHYM INEDQEGCHQLIITTVLPTDMGAYRCTAENSSGITATKAELRVDMSCSSDYDTAADATET SSYVSAKGYMSRETETFESVAEDDQLPQVVDELHDVHVCPGSPIAKLQLKVKGFPKPRIY WFKDGQPLRPSDRVLLLAEGDVHGVEILEVKKEDMGEYSAYISNAAGSAYSSARLMVLRP GEMMPQDKRDPKVPLVPPRFIERFSNRKVKHGASITLSVKVEGSPTPMVSWLKEESVEDV LWIKPDTKGYKIASSGRQHSLILMDVGTEYTGAYTCIATNRAGQSICTAHLEVDDVPQPK KETKLSEVFGFTVSPPEEEVVKAKESKMSYLGEVGTEEFLMKLTTQITEMVSAKMTQDSS QNHEVLQWMKSWPKATTSLRVPGADSDDETKTPSPSPHHGRSRPPSLIADSSSESDEGDA RGEMFDIYVATADYNPTISNKEAISLKEGQYVEVLDSAHPLKWLVRTKPTKTTPSRQGWV SPAYLDKKLKLSADPSDLPENNDEEVTEGEYKRKLFQLIQDLINSESQFVKEVDFFTSHH VKHADSPDAPPDVSSQKEAIFRNIDDIQSFHSRAFLPKLNDCETDDDVAMCFLKNKEGFE KYLQYLVGQSKAESAISDKAVHRFFKEYTDKVQASADPADPPVRSINASLQHPLDRVQKY KAVLKELIRNKAKNGQNCCLLEEAYAMVSALPQRSENTHHVGMIENYPATLEVLGEPIRQ GPFQVWEGAPGIRTSSRGHHRHVFLFKNYCIICKPKRDSNTNTQAYVFKNMMKLNNIDVN EIVEGDDRAFEIWHEREDSVRKYTLQARTVNIKNSWLRDFRELQQRYSTPAWSRPDFDEI LANCTAELGQTVKLACKVTGVPKPTVTWYKDGRAVEADPHHIIIEDPDGSCTLILDNMSA DDSGQYMCFATSSAGNASTLGKVTVQVPPRFVNKMRNATFVAGEDTQFTCVIQSAPNPKI RWFKDSRLLTDQQKYQTYSELRSGVLVLVIKNLTERDLGHYECELSNRLGNAKCAADLAP PSAVARSAEQAITIEVTEQETRIPRKTIIIEETITTVVKNPRMRRHKSPGLTLAGAHRSE TSTPEPPTARPRRMSTQRKTTIPTLYVTQPEGAEARAMESRWVEVEEVIEYKVNKSPRVS RRRGISPATSERSSTPLRAKRSPPERNPNVNNSNNKLLEQAQLQGDVSSSPLSWEEEDGS VSPDAVSGDPHELSSILTQAGEDSEDMDDDQTVIFEPDDEDDNSLGKQEPKILTQGGRVL TLEDLEDYVPEEGENYGSTSTPAAEKPCEISVLQREIGGSAVGQPVLLNVGRPGVGPRQR SGFFGRFREHLSSSLFTPAAPPASGARARTERHVPIQVSHAKLEVKPSYCSEVQRVEGGQ QSFKTKVSTQTYGYTSVGNPVTLQISDNLYQNQ NT seq 19902 nt NT seq  +upstreamnt  +downstreamnt atggatcagaacttgttcggaggagtccccaggtttctcacccgcccaaaggcatgctca gtgtgtgtaggcaaagacgccacacttagctgcactatcgtgggcagcccgaccccgctg ataagctgggagaaggacaagctgaagctgacatctgggggacgtttcaaaaccgtggag gatggaaatctgtaccgcctgaccatctatgacttaacactggaggacaatggccaattc atgtgccgggccaaaaacacagttggggaggcttatgctgctgttaccctcaaagtggcc ctgcaaacagagatggctcagagggcccctgttttcatggttaagcctacctctacacgt gtatgtttgggaggcgatgtggttttccactgccgggttgcagcccaccctgatcccaac tttgattgggagaaagatgggcgctacttgggcgagtcaaatcgtatcaagattgtttcc gacaccgacagcagcaccctgaatatccaaagtgtgcgtaacctggacagcggcacctac acctgcagggcccagaacaccgttggtcgttcacactctgcagcagctctcgttgtagat gcccaggattccctccatctgtccgcagacaagaacacctcctctctcctctctcaccta caaaagcgcaaggaggaaatgaagaaggacatctctatctatcgcactgaagaaagcaga tcctctggttcctcctccaccaagaccagcatcacagatagtttgagttctctgagtcag gaacatgagctgagggcatctgcgctggcaaagctgcccaaaggtgtgttcacccgtacc tgcacggtgactgaaggcaagcatgccaaactcagctgctttgtgacgggtcatcctaaa ccccacatcatctggaggaaggatggatcaaacatcagcgagggccgcaggcatgtcatt tatgaggaccaagctgagaacttcatcctcaaggtcctgtactgcaaacagaccgataat ggtctctacacctgcaatgccaccaatatggctggccagacctacagtgctgtgttggtg acagtcaaagagcctaaggtgccattcaggaggaagctgcaggatgtggaggtgcaggag aagacgtcagccaccctgctgtgtgaggtgcctgttagtgccacccaggccagctggttc atggaggagacgaagctggatcaaagcaccaaatattacatggagcaggaaggcaccctg cttcgcctcaccattcacaacgtcaccaccaacgacgatggtgtttatatctgcgagatg aaggaaggcagccgcactgtggctgagctcaccgtcctgggcaatattactaagaagctt ccccggaggacagtggtccctgtcagcgacactgtcatcttctgtgtggagctggagcgt cctttcccagatgtctactggacccgcaatggcgtgaagctgaagggagattcccgtatc gcaatcgcctgcgtgctcagacagtacacactcactattagagattgccaggctgatgac tcaggagaagtggccttcgtggcgggagactgcaaaacttccacacgattctctgtcact gctgctaggaagcatcctcccgatcccccagtcgatgcagtggttgcgaacaagactgac tcatccatcaccatccagtggtctcctccggacagcgaccgccccgtgcccatcaagtgc tactttgtggagaggaggaaggttggcactcagacatggcagcggtgcaactctggagaa accatcctttctaccgagatcaccgtctgcagcttcaaagaagaagccacctaccagttc cgtatctctgccatgaatgactttggccagagtgattacctggaggtgcctggaagcttc tacctagaacccagtgctgaaatcaggaaaggcctgatgaacagcactgccttcttcagt gaggagttctccatctccgtggagctgtcagctgtttgttctgccttctggtctctgaat ggccgcctcctgcgcagtggaggcgactacctcatcaccaggatcaagaacacacacact ctgctcatccgtaacgtgaccatggaaatgaacgggactgaggtcaagtttgtgggtgga ggctcacaaagcagttgcatcctgtctgtgcaggctcctgttgttaggttcaccaacaag tcaaacctacaggaggtgttctgcagtgcccaggccaccgctcagctgactgctgaggtg tcagattacgatgcacaggtggtctggatgaggaatgggcgggaggtgaaaacggggaag aagtatgaatacatgattgtcgaccgcaagaggatccttatggttcacaacgtgacagag gaagatgtgggcatctatgagtgtgctttagctgatgacaaaatatccctgcagctctct cttaaagatgaacctgccaagttcctgaacaaagccagaggaaccatgggaatgtcatca accctaaaaggagacctggagctgacctgtgaggtttctccagccagcgcggccgtggtg tggaagaaagatcaagtgcagatcaccgaggaccaaagaacgaccaccgtcgccaaaggg actcaaaggaaactcatcatcaaaaacgccaagaaaagtgacgaaggacattactcctgt gagacagcagcagacaaagtcacattccaggtcaagataaaagaaactcaggcagtagcc gccttctccaacagggaatcagtccaaaaggaagttaaagctactctcacccagaaagct actcttagttgtgatgtctctgatagtaagatagaagtgaagtggtataaagacggcaag cagctgatatccagcaggacgatatactcagaagtaaaaggcagtactcgtcagctggtg attgaaaaggtggagaagagcgatgctggagagtatacgtgtgaagcggcaggggataag ctggtcttcaagatatctgtctcagagttccaatcagccttctcgaacaaggagtccgtc cagagcgaagtgaaagccactctctcccagaaagccactctgagctgtgaggtagctgat accaagacagaggtgaagtggtacaaggagggcaagctgctgacttccagcaaaacaatc catacagagacaaaaggcaagagtcgccagctggtgatcgacagcgtagagaagaaggat gctggagagtacatctgtgaggctgggactgagaagctggcatttaagatgcatgtggca gaagctcagtcagctttctccaacaaggagtctgtccagaaggaggtaaaagccactcta tctcagaaatccaccctgagctgcgatgtttctgataccaagacagaggtgaagtggtac aaggagggcaagctgctgacttccagcaaaacaatccatacagagacaaagggtaagagt cgccagctggtgatcgacagcatagagaagaaggatgctggagagtacatctgtgaggct gggactgagaagctggtcttcaaactcaatgtggcagacacacaggtccagtctgccctt tctgacaaagagtcagtccagaaggaggtgaaagctagtctctcccaggcggccaccctg agctgggagatatctgattccaagtccgaggtgaagtggtacaaggatggcaaactcata agcaccactcaggcgatccatgcagagtcaaaaggcaagagtcgccagctggtgatcgac aacgtggagaagaaggatgccggagagtacatgtgtcaagctgggtctgagaagctggtc tttaaaatgcatgtagaaggttcttctacagaagtccacgctaaatcctctttcgtcaac aaagagtctgtccagacggaactgaaagccactctctcccagaaagtgactctgagctgt gaggtagctgataccaagacagaggtgaagtggtacaaggatggcaagctgctgactacc agcaaagccgtccacatggagtcaaagggcaagattcgtgagctggtgatagagaagatg gagaaaaaagatgcaggagagtacatctgtgaagtcggaactgaaaaactggcaattaga gtgcaattgacagaaatccaacagaagttagcattttccaacaaggagtccgtccagagc gaagtgaaagccactctctcccagaaagccactctgagctgtgaggtagctgataccaag acagaggtgaagtggtacaaggagggcaagctgctgacttccagcaagacaatccataca gagacaaaaggcaagagtcgccagctggtgatcgacagcgtggagaagaaggatgctgga gagtacatctgtgaggctgggactgagaagattgcttttaagatacaggttgcagaagct cagtcagctttctccaacaaggagtctgtccagaaggaggtaaaaaccactctatctcag aaatccatcctgagctgcgatgtttctgataccaagacagaggtgaagtggtacaaggag ggcaagctgctgacttccagcaaaacaatccatacagagacaaagggtaaaagtcgccag ctggtgatagacagcgtggagaagaaggatgctggagagtacatctgtgaggctgggact gagaagattgcttttaagatacaggttgcagaacccccggctggtttctctaacacacag tctgttaagcaagaggtgaaagccactctctcccagaaagccactctgagctgtgaggta gacgatacaaagacggaggtgaaatggtacaaggatggcaagctgctgactaccagcaaa gccgtccacatggagtcaaagggcaagattcgtgagctggtgatagagaagatggagaaa aaagatgcgggagagtacacatgtgaggctggaacagagaagcttgtatttaagatgcag gttacagatgcagctgtcaagttccagaaaaagcttgtcaaggacacatgtattgttcaa gcaagtgaaaaagttgttttgaccaccgagctgacgacagagagtggtagtgtgaagtgg tgcagagatggtgtggagctcaaggagggcagcaagtatgaaatgaaaaaagaaggcctt tctcgtaccctgatagtgaaatcgtctgaatccaaagacagtggaacatactcctgtcaa actgctgatgacaaactggagttcaaagttcaagttaaagattcggctttgaagtttgtt gtccctttgaaacctgctacagtggatttggaaggcacactcagcctgatgtgtgagcta aatcaagcctcaggggatgttgtctggcagcatgatggtcgtgagattaaacctggaggc aggtactgtgtgaggacagatggtgctaagcgggtcctcaccgtgactggcatgactaaa gaagatgaaggagaatacagctgtgaatgtagaaatgacaagacctccgccaaagttacc tcaaaagcacccagactggtgaggctgactactaaactgaacaatgtggctgccatggag ggaaaagatgcaattttcaagtgtgctgtcaacccagcagacgtcaacgttaaatggttc cacaacagcatacccgtcactgctgggcccaaatataagattgggcgtgggggcagcagt cactcactcaccatcacctctgtcacacaaaaagatggcggagagatcagcgtggatgca gagggcaaaagctgcaaagccaacctacaagtggagcatgaacctgtgacttttaagaaa atgctagaaaacctgacagtggaggagcagagtgaagtgaagctggagttggagctgagt aaggtgtcggatgaagtgaggtggatgaagaacagcgttgtgctgcagccttcaggaaac atggagattcaggtcaacggagccaagcaggcactgatcttcaagagcgtggcttatgct gaccggggcatctactcctgtgaaaccctggatgacaaaacccaggccaagctcagtgtg gagatgaaaaagatccaggtaattaagggcctaacagaaaccaagtcacatgagacagag acggtaactctggaggtagagctcagccaggctgatgttgagggcttctggaccagggat ggggccaagttaaagtcaggggccaactgccgtatcacagctttcggaaagaagcattct ttaacgttgtccaatctcaagagggaggacgcaggaatgattgccttccaagcagaagga gttcataactctggcacactggttgtcacagaacttcctgctatgatcgccaagcccatg gtagatatcagtgtcgctgataaggaaaaggttacttttgaatgtgaagtgtccaaaacc aatgcagatgttaaatggttcaaggatgatgttgaactgaaaccagggaagaactttggc atccattccttgggccgaaagcgcagtttggtcatcaacaaatgcacccctgaagatgca ggcacttacatctgtcgcactactgatgataacacctcagctaaactcactgttaatgcc cgagaagttaagattgttaagaagctggaggatgtggaagtgatggagaaggagagtgct gcgtttgtctgtgaagtatcacatgatgaagttgaatgccaatggtacaaaggaagtacc aaactcaaagtcggtgacaacatcaagatgagacaagagggcaaaacctatgtacttctg tttaagtctgtcaccattgaagatatgggtgagattaaattcacagctgacaaggcctct tcagcagcaaaactgaaagtgaaagagctgcctgtcaagtttgtgaagaaactcagggat aagatagcgatgtataagcatcgtggacatcttgaatgccaagtgtcacgtgccagcgca aaggtgaagtggttcaagaacaagacggagatcaaacacggcaagaagtacgagatcaaa agtgaagatgtgtaccgaaaactcaccatcaacgatgtggcatccggggacgaagacacc tacacctgtgacgccactgatgaaaagacatcctgtaaactacttgtggaagagcagtgc atcagcattgtgcgggagctgacatcagtagaagtgacagaaccatttgcagctgttttc gaagttgaaatcagtatggaactggtgaaacctcccatatggactctgaatgcagttgct gtgaaggagagcgccgatgtagaaatggagaaagagggcacaatgcacagtctcactttc aaaaagaccaaagcatcgatgacaggacctgtgcagtttacagctggcaagagcaaatct ttagcccagctcacagtcaaagagcgtccgcttgagattacagagcccatcaaagatgtc aaggggaaagagaaaagctctgcgatactcacctgtaaattctctgcctcacccaaagag gtagcgtggttcaaaggccaggtgcctctgaccgcttcagacaagtacaacatgaagcaa gatgctacaagggctcaactaactattcaaaggttgactgaggaagacagtggagattac cgctgtcagtccggacctgctgaggccaaagggacccttactgttgaagtgcgtgaaatg aagatcagcaagcacttggcagacacagaggttgatgaagacaacgatgctgtgttcaca tgtgagataaactatgctgatgaagaggtacagtggcttctgaatgacaaggtgctcttc accaatgaagtcaacaccatcgcacatgatgggaaggtccacaagctcacactgaagaac ttggcacctcaggacggggggactatcacctttcaggtccgcaaggtgaaggagtcagtg acacttaaggttaaagagaagcgagcagtgttcctcaagtctctggatgatgtcattgga gaggaaaagggcatgataactctggcgtgcgaggcgtccaagcccagggtttctcctgta tggagaaaagaagttaaagtcctaaaggccggatcaaagtatgagctccttcacacaggc aagtctttggggctgatcatcaaggacgtcaccaaagaagatgctggagagtacagttgt gatctaggaactgaggtttctaaagcaaaggtcactgtaagagagattgccattggaatt accaaatggctgaagtcggctgaggtgaatgagggagactcatgtaactttgagtgcatc ttatctcgtgagagcacagacgagtgttcctggactcttaatggaaacactatcacagat ggaggtcgcttcaaagtcaccagtaaaggacgcaaatacatgctgaccatcaaggatgtg actcctgctgacgctggagaggtggtcttgaacattaaagaccttaactccaaaacaaca ttaaaagttgaaggcaaggcttcatccgtgtctaaaggactacagagtgttagtgctgtc caaggagaagatgctgtatttacctgtgaggtaacaaaagctagttccactgtaaactgg tccatggaaggcaaagccatcaaaaagagccagaagtatgacatcagacaagaggaaaag gtcatgaagctgacgatccataacatctcagctcaagactccggagagtacagttgtgaa gttgttggaggtgcaaccactaaagccaagctggaaatcaaggagccaattcataaattc actaaagagctgaaggacagccaagctgaggagaagagcaacgtgaccttgcaatgtgag acggcacaaaccccatccactgtggtatggcttaaaggtcacacagagctcaatgctgga ggtcgatatgagatgtcccagaaggagagggtcctaactctgaccatcaaacagctggag gagaaagacacggatatctacacgtgtgacgtgggcacggcaaagatcatggcaaaggtg acagtcaatgccctgcctgccaattttaaagagaagctcaacaaccaggggagaaaggaa ggggagtcggtgaaactctgctgcaaactatcgaagcatgctgatggcgttcagtggaag aaaggctctgaagttctcaaagctggagagaagtatgagatgaagatggaggagacttct tgtgaacttcagattaagaatttggaggttgaagatagtggagagtactcttgcttgtgc ggggaccagaagacatctgcaactgtgaaagtcactgcactgccgccgaccttcaaacag aagctggagagccaggaggctgaggagggggctagtgttactctgcgttgtgagctctcc aaacctggagtccctgttgagtggaagaagggaacaaaggtcctgaagtctggagaaaag taccagatgaagcaggaggcctctgtgaataaactcctcatcaacaaagtgctgccagag gacagtggagactacagctgtgtgtgtggagacctgaagaccacagccagtctcaacatt aaggcccaaccagtgaccttcaaacagaagctggagagccaggaggctgaggagggggct agtgttactctgcgttgtgagctctccaaacctggagtccccgttgagtggaagaaggga acaaaggtcctgaagtctggagaaaagtaccagatgaagcaggaggcctctgtgaatgaa ctgctcatcaacaaagtgctgccagaggacagtggagactacagctgtgtgtgtggagac ctgaagaccacagccagtctcaacattaaggcccaaccagtgaccttcaaactaagattg gagagccaggaggctgaggagggggctagtgttactctgcgttgtgagctctccaaacct ggagtccctgttgagtggaagaagggaacaaaggtcctgaagtctggagaaaagtaccag atgaaacaggaggcctctgtgaatgaactcctcatcaacaaagtgctgccagaagacagt ggagactacagctgtgtgtgtggagacctgaagaccacagccagtctcaacattaaggcc caaccagtgaccttcaaacagaagctggagagccaggaggctgaggagggggctagtgtt actctgcgttgtgagatctccaaacctggagtccccgttgagtggaagaagggaacaaag gtcctgaagtctggagaaaagtaccagatgaagcaggaggcctctgtgaacgaactcctc atcaccaaagtgctgccagaagacagtggagactacagctgtgtgtgtggagacctgaag accacagccagtctcaacattaaggcccaaccagtgaccttcaaactaaaattggagagc caggaggctgtggagggggctagtgttactctgcgttgtgagatctccaaacctggagtc cctgttgagtggaagaagggaacaaaggtcctgaagtctggagaaaagtaccagatgaag caggaggcctctgtgaatgaactgctcatcatcaaagtgctgacagaagacagtggagac tacagctgtgtgtgtggagacctgaagaccacagccagtctcaacattaaggcccaacca gtgaccttcaaacagaagctggagagccaggaggctgaggagggggctagtgttactctg cattgtgagatctccaaacctggagtccccgttgagtggaagaagggaacaaaggtcctg aagtctggagaaaagtaccagatgaagcaggaggcctctgtgaatgaactgctcatcaac aaagtgctgccagaagacagtggagactacagctgtgtgtgtggagacctgaagaccaca gccagtgtcaagatcaatgctcctccttcagcttctaaaccagaatctaagagtcaggag tccaaagaaacaatcgaagcaaaagcccctgaagctccctccaaagttgctcaagatgag cggaagaagcaagagataaatgagacagtagaagctgtaacacttccacgtactggacag actcctcaacagcagctcctcaaagtggaggtacataaggattctcaagagcttaaagtt gcaggggaagttgagaagacggctgctggaacagctgctgacacaaagaggcaggggacc aaagagccactagaagcccagcctgtccttttcaaaacccagctgcagaaccttataaga caggaaggggagagcgctagtcttcgctgtaaaaccacaaagccgggagccagtgttgtc tggaggtttggagacagggtgctggcatccagcagcaagtatcatctgaaacaggaaggg actgtagttgagcttgtcatctataaactgcgaggagctgactcgggagaatattcttgt gatgcaggaaaccagaggacttcagctgtcctcagtgtgcaggaggtcgaggttacaata ctgaagttcttggagagctgcgttgtgtaccagggtgacgatgtccgctttgaatgtcgg gtttctcgtgaggaggcacctctggcccagtggaaactccaggatgtcccactacagaat aacgagatgaacctgatcaagtctgagggctgcgtacacagcctcaaactccggggcgtc accacggctgactcgggaactgtcactttcacagtgggtaaccacacatcaactgcttct ttgacagtcaaagccgctcctgcaacattcaagaaggagctggaaagtcaagaggccatt gaaggagacaaagccagcctgtcctgcgagacttccagccccgactgcaaggtgacctgg ctgaaagactccactgtgctcatccatggggagaagtacagtttggagcaaaccgctaca acgcacatcctggtgatacacaagctggatgtgaaggatagcggagaatatacctgcgaa actggggacaagaaaagtacagctaccctgaccgtgaaagcacgtgttcgcatcactcga gaactcagcgatgttactgtgacaacggggcaggatgctgtctttgaggtggagttgtca cacccaggcgtgacaaacagcgaatggtggcttgcagataacctcctccagaataatgac ctgaatcaaatgagcagccagggcacagtgcaccgactgaccctgaagatggtgaccaca gatgaatctggagatgttgccttcgtgttgggagaagagaagactgtggcctgtcttctg gtggaggagaagcccaaagtgctaatactagagaaaccacacaacacttcggcagtagag ggtgaaactgtcactctggcctgcaccatctctgacaccaaggcttctgtcacctggaag agaaacaacacggccatccaagcaggtctcaagtacgacctgaagagtaacggagctctt caccagcttagtatcaacaacctggtgcctgaggactcaggaacgtacacgtgtgacact ggagatgcacagtgtgactccaccttgactgtgcaaggtacccccgtgtccttccgcaag gagctcaagaaccacgatgccatagagggtgatgatgttaccctgcactgcgagctgtct aagccaggtgttcctgtggagtggaggaaaggaggcctggtcctcaagcccggtaagcag tttgagatgaagcaggaaggatgcattcaagagctctgcatacggaacgtggagcccgag gacagtggctactacacctgtgatgcgggagaccagctcaccacggcttctttggcagtg caagcgaaagaagtttcctttgtgtgtggtcttaagaccactgacgtctttgttggggaa tgggcaaccttctcctgccagctgtctggtagggcccctcacaaggtgcagtggtggctg gatggcaccttgctggagaacagcccctttagtgaaatagggctgagcccaggcaacatc cacacactcaccttaaagaacctggccaccgatgactctggcactgtcacattcgaagct ggcagtttaacatcaacagccaagctcttagtcaaagatcccacagttgaagtggtgagc gagctggaggacattcgggtgctcgaaaaccaaccggctgagttcatctgccagttctca cggccggtcaagcctcagtggaaaaaagatgggcagccattacagcctgatggccgaagg gtggtagtggagcaggactggaatgtggctcgcttgtatattagccatgtgtctgctgag gacaggggaacatactcctgtgaggcagaggggacctgcgcggtcgcttcactttttgtg gaaggaaaacccattgacattgtccagggcctggagaatgtagaaacctttgatggaggt gaagtgctgcttgagtgtgccctgtctcgtcctgagagcaaagattgccactggttcctc gatgggaaaccagtaaaggaatcccctaatgctgagattgtaacatttgagagtggtcgt cgtcatctgctccttctgaaagagttgcgagtgacagacagttgcacagtgactttcaaa gttggcacagcctccacatcggcccaactctccgtcaaacgctggcaactggatgttgtg aagagtctggaggacaaggtggctgcagtgggagaaaaggttgagtttaatgtcgaactc acagagcctgtcccttcagcagaagtagcctggtatatgaatggggttgagatcaaaccc agcgacctctgggccttgagagctgacggctgttcttatcgcctcgtcctgaggaaggcc cctctaatgccacagcaagaaattacatttgctgctagagatgctctctctttggccaag ctcaccatcatcactgtacctgatcctccagaggacccagaagttctcactaagacagaa aggtctgtcaacctgtcttggttcactcctctacatgatggagggagtcccattctggga tacagggtggagatgcgtctggtggacagttccctctggctcccatgtcactctgaccct gtgtttaacacagagtttgtggttgaaaatcttacagcagggagtggctacaggttcaga gtggcagccactaacagagctgggattggagagcctgttgagatgccacacactgtgcag cttgaagcaccaatccagccagcagtttgcccaggtgtagaagccaaacagactgaggct gagactatgggacaacccagtctgcctccagaagctgctgaagaaggtgatgttcatgag ctgtgggaggaatcggccaagaaacgccgcatgagtcgtgaacccactctggactccatc actgaacaacctgaggaagacggtaaaggtggtaaaaagaagtcagagaaagtggaaatt aaatcagaagagaaggagctggccattgtgtctaagacgcaggtagagtccaaaattagc accacctcagaggatgagtctgtttctgggggttcaacacttgtctcctacctcaagaaa agcagcacttcttctgtcacagcaaccaatgagagagagactttgactactgagaagttc ttcgcacatttcaagatggaagagcagacagtgcaggagtctagggtggaaacaaccata atacagcagacagatgcaaaacaggtgtcaacagaggagactgagatcatggagatcagt aaagaggatgagcctgaactcagagatgctgccattaagattcaagcggccttcaagggc tacaaagcccgcaaggacatgcgccctgtctttaaagatgccttcaaagaccagaccaaa gaacctaacggcactatacatctagaatgcattgcagaaggtaaacctgataaggtgcgc tggctgaaggatggagaaccactgactgatggcaagcaccaccatattgatatctacaat gatggcacttgctcactggttatcactgccatcaccataaaagatactggggtctacaca tgtgaggtcaccaacaagtatggagtcacgtctcacagtggtaaggtcacagtaggaacg gagagagaatcatctgggcggcggccgctgaccgtgggctacagtgccgacagcgagccg gacagctcctcaggaagtgagatggatgagtctctgaggcaggcaagcaaacgtctgtgc cgcctgctgcgatcaagtctccctccgaatgttgaggaagaatcatttgtcagcgcagat gaaggagacctgggtcctccagatccacactcttaccgggaggacgactgttacatctac attcgttttgactcccggacagaggctgaggttgcttcaaagaggtttcaggagatgttt acaatccatggggttcctgtggataccagcatcctggaggctgggcctctcaaagtggag ctgcgaattagaaagatgggctacatgcaagatggcgcacagacccccacacaagaaaga cagccagttgcgtttatggctggagcccaggctgccccagtcttcttgactgagctacaa agtcaggatgttcctgacggttatccagtcagctttgactgtgttgtgattggcaagccc cctccctccgttcgctggtacaaggacggtaaattgctggaggagaatgaccattatatg attaatgaagatcaggaaggctgccaccaactcatcatcaccaccgtgctgcccactgac atgggcgcctatcgttgcacagctgaaaacagcagcggcatcactgccactaaggctgag ctcagggttgacatgtcttgcagctcagattatgacactgctgctgatgccactgagaca tcttcctatgtcagtgccaagggctacatgtccagggaaactgagacctttgagtctgta gctgaagatgatcagcttccacaagttgtggacgagcttcatgatgttcatgtctgtcca ggttcacctattgctaagctgcagctcaaagtaaagggcttccccaaacccagaatatac tggttcaaagatggccagcccctgcgcccttcagacagggttctgctgctagcagaggga gatgttcatggtgttgagatcctggaggtgaagaaagaggatatgggagagtactctgct tacatcagcaacgcagctggttctgcatactcctctgcccgcctgatggttctgcgtcca ggtgaaatgatgccacaagataaaagagaccccaaggtgcccctggtgccgccccgcttc attgaaaggttcagcaacaggaaggtgaaacatggagccagcatcactctgtctgtcaaa gtagaaggctctcctactccaatggtctcctggcttaaggaggagtcagtggaagacgtc ctgtggataaagcctgacaccaagggatacaaaatagcaagctcagggcgccagcacagc ctcatcttgatggacgtgggcacagagtacaccggagcctacacctgcattgccaccaat agagcgggacagtccatctgcacggcccacctcgaggtcgatgatgtaccacaaccaaag aaagagaccaaactatcagaggtgtttggattcacagttagtcctccagaagaggaggtt gtcaaagcaaaagagagtaaaatgtcctacctaggtgaagtaggtacagaggaattcctc atgaaactgacaacccagatcactgaaatggtatcggcaaagatgacccaagacagttca cagaatcatgaagtgctccagtggatgaaatcttggcccaaagctaccacttcattacgc gtaccaggtgctgacagtgatgatgagaccaagactccttctccttcacctcatcacggc cgctctcgtcctccctctctcatcgctgactcctcctctgagtctgatgagggggatgcc aggggagagatgtttgacatatatgtcgcaacggctgactacaaccccaccatatcaaac aaagaagccatctctctgaaggagggacagtatgttgaggttttggactcagctcatcct ctcaagtggttagtccggaccaaacccaccaaaactacaccatcgcgccaaggctgggtc tcacctgcctacctggacaagaaactcaaactatctgctgatccgagtgaccttccagag aataatgacgaggaggtgactgagggtgaatacaagaggaaattattccaactgatccaa gacctgataaacagtgaatcacagtttgtgaaagaggtcgacttcttcacctcccatcac gtgaagcatgcagacagccctgatgcaccgcctgatgtcagcagccagaaggaagccata ttcaggaacattgatgatatccagtctttccacagcagggcattcctcccaaagttaaat gactgtgaaacagatgatgacgtagccatgtgcttcctgaagaacaaggagggctttgag aagtatctccaatatcttgttggtcagagtaaggctgagtcggctatcagtgacaaggcc gttcaccgcttcttcaaggagtacacagacaaagtgcaagccagtgcagaccctgctgac ccccctgtacgcagcatcaacgccagcctccagcacccactggacagggtacagaagtac aaggcggtcctcaaggagctcatcagaaacaaggcaaagaatggccagaactgctgcctc ctggaagaagcgtatgccatggtgtctgcactccctcagcgctctgagaatacccatcat gtcggcatgatcgagaactatcctgccacactggaagtattaggagagccgataagacag ggacccttccaagtgtgggaaggcgctcctggaataaggacgtcctctagaggtcatcac cgccacgtcttcctgtttaagaactactgcataatctgcaaacccaagagagacagcaac acaaatacacaagcatatgtctttaagaacatgatgaagttgaataacattgatgtgaat gagatagtggagggtgatgaccgtgcctttgagatctggcatgagcgcgaggactctgtg aggaaatacaccctgcaggcccgaactgttaacatcaagaactcatggctgagagacttc agagaactgcagcagcgatacagcacgcctgcatggagtcgtcctgactttgatgaaatc ctggctaactgcacagcagagctcggtcagactgtaaagctggcctgcaaagtcactgga gtccccaaacctacggtcacgtggtacaaggatgggcgtgctgtggaggcagaccctcac cacatcatcatcgaggaccctgacggttcctgcacgctgatcttggacaacatgagcgca gatgattctggacagtacatgtgctttgccacaagctcagcaggcaatgccagcactctc ggcaaggtcactgtccaggtgcctcctcgctttgtgaataaaatgcggaatgctacattt gttgctggtgaggacactcagttcacctgtgtcatacagagcgcccctaaccccaagatc aggtggttcaaggacagcaggctgctgactgaccagcagaagtatcagacctacagcgag ctccgcagtggggttctggttttggtaatcaaaaacctgacagagagagacctgggacac tacgagtgcgagttgtccaaccgtctgggcaatgctaagtgtgctgctgatttggctcct ccctctgctgtggcccgctctgctgaacaggccatcactattgaagtcactgagcaggag acgagaataccaaggaaaaccatcatcattgaggagaccataaccactgtggtgaagaac ccacgtatgaggcgacacaagtcccccggcttgactcttgctggagcccaccgctccgag acctccaccccagagccccctacagccaggccgaggaggatgtccactcagagaaagacc accatccccaccctctatgttactcaacccgaaggcgctgaagccagagccatggagagc aggtgggtggaggtcgaggaggtcatcgagtataaagtcaataaatctcccagggtgtcg aggaggagaggcatctccccggcaacgtctgaacgctcatcgactcctttaagagccaag aggtctccacctgagagaaaccccaacgtcaacaactccaacaacaagctgctggagcag gctcagctgcagggagacgtcagcagctccccgctctcctgggaggaagaggatgggagc gtttccccggatgctgtctctggagacccccatgagctctcctccatcctcactcaagca ggagaggacagcgaggacatggacgatgatcaaactgtcatctttgagcccgatgatgaa gatgataactctctcggtaagcaagagcctaagatcctgacacaaggaggccgtgttctg actctggaagacttggaggattacgtgccagaagaaggtgaaaactacggctctaccagc acccccgctgctgagaagccctgcgagatctcggtgctgcagagggagatcggcggctcc gcggtgggacagccggtgctcctcaacgtgggccggccgggcgtggggccgaggcagagg agcggcttcttcggccgcttcagggagcatctctccagcagcctcttcacgcctgcggcc cccccagccagcggagctcgggccaggacggaaagacacgtccccatccaagtgagccac gctaagctggaggtgaagccttcgtactgctccgaggtgcagcgggtcgagggcgggcag cagagctttaaaaccaaagtgtcaactcagacctacggctacacttcagtgggcaaccct gtcactctgcaaataagtgataacctttatcagaaccagtag

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