Trypanosoma brucei gambiense: TbgDal_IV2670
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Entry
TbgDal_IV2670 CDS
T06526
Name
(RefSeq) 3-hydroxy-3-methylglutarate-CoA lyase, putative
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
tbg
Trypanosoma brucei gambiense
Pathway
tbg00280
Valine, leucine and isoleucine degradation
tbg00650
Butanoate metabolism
tbg01100
Metabolic pathways
tbg04146
Peroxisome
Module
tbg_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
TbgDal_IV2670
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TbgDal_IV2670
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
TbgDal_IV2670
Enzymes [BR:
tbg01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
TbgDal_IV2670
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Motif
Pfam:
HMGL-like
EF-hand_7
EF-hand_6
EF-hand_1
Phage_HK97_TLTM
Motif
Other DBs
NCBI-GeneID:
23859690
NCBI-ProteinID:
XP_011772855
UniProt:
C9ZMR3
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All DBs
Position
4:677396..678691
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AA seq
431 aa
AA seq
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MFRTLPLRSSIRMVECPRDAMQGLPHFIPTEQKIRYLKALLKCGFYALDCGSFVSPRAVP
QMRDSTEVIANCWKTMQEEKAAPKLSVVVASLAGFKQALETPGVSVIGYPIGCCERFQQR
NAKKSIAMSLDEIRNIKEATDAFNAQRSSNPVAPNEDVNGRELLIYISMAFGNPYGESHS
IDLVENLVGELVASGARDISLADTTGVAQPPLIFDTFTQLRKKFPDVTFAGHFHSNAVEA
RGKIVAALDAGCTMIDSALCGMGGCPFAKDDGLVGNVATEVVVKALEERGVLPAALNKEQ
LKKCVLIKQEIFGVSVRDMLISQTLHDEKRFAALCQEHFKLYDVNDDGTLDYEGFRDSMI
HVFAELGAPQPSEEKIRSSFAKVDIQNLGFITIDAYTMGARRLLVKRLASNTNTTTKNEE
RGEGVVEASSC
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgtttcgaacgttacccttgaggtcaagtattcgcatggtggagtgcccgcgcgatgcg
atgcagggcttaccacattttatcccaacagaacaaaagatacggtacctcaaagctctc
ctgaagtgtggcttttatgctcttgattgtggctcttttgtgtcaccgcgagcagttcct
caaatgcgtgatagcaccgaagttatcgctaactgttggaaaactatgcaagaggaaaag
gcagcgcctaagttgtctgttgttgttgcatcactcgctgggtttaagcaggcattggaa
actccgggagtgagtgtcattgggtatccgattggttgctgcgagcggtttcagcaacgt
aatgcgaaaaagagcattgcaatgtcccttgatgaaattagaaacataaaggaggccaca
gatgccttcaatgcgcaacgaagctcaaaccccgtggctcccaatgaagacgtcaatggg
agggagcttctcatttacatttctatggcatttggtaatccgtatggcgagtcgcacagt
attgatttagtggaaaatttggtaggagaacttgtcgcatcgggggcgcgtgacattagt
cttgctgacaccactggagtagcgcaaccgcccctcatatttgacaccttcactcaatta
cggaagaaattccctgatgtaacatttgctggacattttcacagtaatgcggtggaggcg
agagggaaaattgttgcagcgctggatgccggttgcacgatgatcgacagcgcgctgtgt
ggtatgggcggttgcccattcgctaaagatgacggtcttgtgggaaatgttgcgacggag
gtggtggtgaaggcgcttgaggagcgtggcgtcctccccgctgctctcaataaggagcaa
ctaaagaaatgcgtcctcatcaaacaggagatttttggtgtgagcgtgagagacatgttg
atttcacaaacactgcacgatgagaagcggtttgcggcgttatgccaggagcactttaag
ttgtatgatgttaacgacgatggtactttggattatgaaggatttagagatagtatgatt
catgtctttgctgaattgggtgcaccacagccatcagaggagaaaatacgcagcagtttc
gcgaaggttgatatccaaaatcttgggtttattacaattgacgcgtacacgatgggtgca
aggcgcttactcgtcaagagattggcttccaacaccaacacaacaactaagaatgaagaa
aggggggaaggtgtcgttgaagcatcttcctgctga
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