Trypanosoma brucei gambiense: TbgDal_X680
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Entry
TbgDal_X680 CDS
T06526
Name
(RefSeq) 2-oxoisovalerate dehydrogenase alpha subunit,putative
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tbg
Trypanosoma brucei gambiense
Pathway
tbg00280
Valine, leucine and isoleucine degradation
tbg00640
Propanoate metabolism
tbg00785
Lipoic acid metabolism
tbg01100
Metabolic pathways
tbg01110
Biosynthesis of secondary metabolites
tbg01210
2-Oxocarboxylic acid metabolism
Module
tbg_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tbg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
TbgDal_X680
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TbgDal_X680
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TbgDal_X680
Enzymes [BR:
tbg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
TbgDal_X680
SSDB
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Paralog
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
23865781
NCBI-ProteinID:
XP_011777253
UniProt:
D0A145
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Position
10:<116525..>117775
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AA seq
416 aa
AA seq
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MLRVSCRFFGALQEIFSRGQGVWNLDFGNSPTTEDLIFNSAPKTSTPPFHVLDLEGNIVN
KINEPVVPKETLVKIMETMIRSNTIDNILLEAQRQGRISFYLTALGEEATVVGTAAGLEI
RDEAFLQYREAGFLLYRGYKIPQLVAQCMGNVEDVLKGRQMPIHYGSRELNVHMVSSPLA
TQIPHAAGAGYAFRLENEELSDESKSRVAVVIFGEGAASEGDFHGGVNFAAATGSNTLFV
VRNNGYAISTPTRVQYKGDGVLARGIGYGIPSARVDGQDVLAILQAVQQARQIIRTTNQP
VLIEALCYRLQHHSSSDDSGMYRSSDEIENFLALSPLDRFEKFLVKQDLWTAEHTGALAK
QVREELLQELRRQELLPHWPADVMHDDVYKVKTPDLVKAQKELQAHYERNRGFYGK
NT seq
1251 nt
NT seq
+upstream
nt +downstream
nt
atgctccgagtctcgtgccgtttttttggtgcccttcaggaaatcttttctcggggtcaa
ggggtttggaatttggattttggtaactcgccgacgacggaggatctcatcttcaactcg
gcccccaagacctcgacacccccttttcacgtcctcgaccttgaaggtaatatcgttaac
aaaataaacgaaccagtggtgccgaaggaaacattagtgaagataatggaaacgatgata
cggtcaaatactatcgacaacattcttttggaggcgcagcgacagggtcgaatttcattt
taccttaccgcattgggtgaggaggccaccgtcgttggtacggctgcaggattagagata
cgggatgaggccttcctgcagtatcgtgaggctgggttcctcctgtaccgtggttataaa
atcccacagttggttgcgcaatgcatggggaatgtggaagacgtgctgaaagggaggcag
atgcccatacattatggatcgcgggagttaaatgtgcatatggtaagttcgccactcgca
acacagattccacatgcggcaggtgcgggttatgcttttcggcttgagaatgaggaattg
tccgatgaaagcaagtcacgagtagccgtagtgattttcggtgaaggagcagcgagtgag
ggagatttccatgggggagttaactttgccgctgctacgggatctaacactctcttcgtt
gtacggaataatggctatgctatttcgactcctacgcgtgtacagtacaaaggtgatgga
gtgctagcgcgtggtatcggctatggtattccatctgctcgagtggatgggcaggacgtg
ctcgcaatattgcaagccgtccagcaagcacgacaaatcatacgtactaccaaccagcct
gttctaatcgaagctctttgctatcgtttacaacaccactcctcttctgatgatagtggt
atgtaccgttcaagtgatgaaattgaaaacttcttagcgctctccccacttgatcgattt
gaaaaattccttgtgaaacaggacttatggacagctgagcatacgggggcgctggcgaaa
caggttcgtgaggaactgttgcaggagttacgtcgacaagaattgttacctcattggccg
gcagatgttatgcatgatgatgtctacaaggtaaagacaccagacttggttaaagcacaa
aaggaattgcaagctcactacgaacgaaacaggggattctacggcaagtga
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