Thermoanaerobacter brockii: Thebr_0019
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Entry
Thebr_0019 CDS
T01409
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
tbo
Thermoanaerobacter brockii
Pathway
tbo00290
Valine, leucine and isoleucine biosynthesis
tbo00770
Pantothenate and CoA biosynthesis
tbo01100
Metabolic pathways
tbo01110
Biosynthesis of secondary metabolites
tbo01210
2-Oxocarboxylic acid metabolism
tbo01230
Biosynthesis of amino acids
Module
tbo_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
tbo00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Thebr_0019
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
Thebr_0019
Enzymes [BR:
tbo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
Thebr_0019
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ADV78651
UniProt:
E8USW3
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Position
20547..22226
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AA seq
559 aa
AA seq
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MRILVSDSIKKGVEKAPHRSLLYALGLTYEEIKRPIIGVANSKNEIIPGHIHLDKIAEAV
KAGIRMAGGTPIEFSTIGVCDGIAMNHKGMKYSLGSRELIADSIEIMATAHGFDGLVLIP
NCDKIVPGMLMAAARLNIPAIVVSGGPMLAGKCNGEVCDLSSVFEAVGAHKIGKISEEDL
YKIELNACPTCGSCSGMFTANTMNCLTEALGLGLPGNGTIPAVYSERIRLAKQAGIKIME
LVERGIKPSYIITKEAFINAFSLDMALGGSTNTILHLKAIAHEAGVEISLDEINDISGRV
PNLCKLSPAGKYHIEDLYFAGGVSAVLKELTKANLINTEALTVTGKTLGENIKDAKVLNH
DVIRPIDNPYSSTGGLAILYGNIAREGAVVKASAVAKEMLRHEGPAKVFNSEEEAIAAIY
GGKIQKGDVVVIRYEGPKGGPGMREMLSPTSALAGMGLDKDVALITDGRFSGATRGASIG
HVSPEAMEGGEIAIIEDGDIIEIDIPARKINVKLTDEEIKERMKRWVRPEPKIKTGYMAR
YAEQVTSANTGAVFKGGGI
NT seq
1680 nt
NT seq
+upstream
nt +downstream
nt
gtgaggatattggtaagtgatagcataaaaaagggagttgaaaaggcgccacataggtca
cttttatatgctttaggcttgacttatgaagaaataaaaaggccgattatcggtgtagca
aattcaaaaaacgaaattataccaggacatattcaccttgataaaatagctgaggctgta
aaagcaggcatcagaatggcaggaggaacgcctatagaattttccactatcggcgtttgt
gatggtattgccatgaaccataaaggtatgaaatattcactgggaagcagagaacttata
gcagatagcattgaaattatggcaacagcacacggatttgatgggcttgtgctgattccc
aattgcgacaaaatagtgccgggaatgcttatggcagcagcacgcctaaatattcctgca
atagttgtaagcggaggcccaatgcttgcaggaaagtgtaatggagaggtgtgcgattta
agcagcgtctttgaagctgtaggagcacataaaatagggaaaatctcagaggaagacctt
tataaaatagaacttaatgcttgtcctacttgtgggtcctgttcaggaatgtttacggca
aatactatgaattgcttgacagaagctttaggattagggcttccgggaaatggcacaatt
cctgcggtttattctgaaagaataagacttgcaaaacaagctggaataaaaatcatggag
cttgtagagagaggaattaagccttcttatataatcacaaaagaggcattcataaacgcc
tttagtttagacatggctttaggcggttccacaaatacaattttgcatttaaaggctata
gcccatgaggcaggggtagaaatatctcttgatgaaataaacgatataagcgggagagtg
cctaatttgtgtaagttaagtcctgcaggtaaataccacatagaggacttgtattttgca
gggggagtatcggctgttttaaaagaactgacgaaagctaatcttataaatactgaagcg
ttaacagttacaggaaagacattaggagagaatataaaagacgcgaaagttttaaatcat
gatgtgataaggccaatagacaacccttacagcagtactggaggtcttgcgatactgtac
gggaacattgcaagagaaggagctgttgtaaaagcatctgctgtagcaaaagagatgtta
agacacgaagggccagcaaaggtgtttaattctgaggaagaagccatagctgcaatatat
ggaggaaaaatacaaaaaggcgatgtagttgtaataaggtatgaagggccaaaaggtggg
ccgggaatgagagaaatgttaagtcctacttcagcccttgcaggtatgggacttgacaaa
gatgtcgctcttataacagacggcaggttttcaggtgcaacaagaggggcttcaatagga
catgtatctccagaggctatggaagggggagaaatagcgattattgaagatggggatatt
attgaaattgatattcccgcaagaaaaattaatgtgaaattaactgatgaggagattaaa
gaaagaatgaaaagatgggtaagacctgaaccaaagataaaaactggttatatggcaaga
tatgcagaacaagtgacttctgcaaatacaggtgcagtttttaaggggggaggtatatga
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