Trypanosoma brucei brucei: TB927.1.1930
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Entry
TB927.1.1930 CDS
T01013
Name
(RefSeq) phosphatidylinositol 3-kinase, putative
KO
K00914
phosphatidylinositol 3-kinase [EC:
2.7.1.137
]
Organism
tbr
Trypanosoma brucei brucei
Pathway
tbr00562
Inositol phosphate metabolism
tbr01100
Metabolic pathways
tbr04070
Phosphatidylinositol signaling system
tbr04136
Autophagy - other
tbr04145
Phagosome
Brite
KEGG Orthology (KO) [BR:
tbr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
TB927.1.1930
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
TB927.1.1930
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
TB927.1.1930
04136 Autophagy - other
TB927.1.1930
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tbr04131
]
TB927.1.1930
Enzymes [BR:
tbr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.137 phosphatidylinositol 3-kinase
TB927.1.1930
Membrane trafficking [BR:
tbr04131
]
Endocytosis
Macropinocytosis
Kinases
TB927.1.1930
Rab GTPases and associated proteins
Rab associated proteins
TB927.1.1930
Endosome - Lysosome transport
TB927.1.1930
Autophagy
Autophagosome formation proteins
PI3K complex
TB927.1.1930
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3_PI4_kinase
FAT
FATC
HEAT_ATR
TFCD_C
Motif
Other DBs
NCBI-GeneID:
4357268
NCBI-ProteinID:
XP_001218895
UniProt:
Q4GZ26
LinkDB
All DBs
Position
1:501553..510264
Genome browser
AA seq
2903 aa
AA seq
DB search
MPRYTAMRRLGPVGHSGGISSNGVTTVGAVTASNVGNGVVNIGGDGSQGVAMGPGATDVA
SARPLLIVPNTTSAAGGSADVSDEEVDQLLRELERSVDSPQAAAVMRDAVWAIERRAFSS
CDPHSRDYFLESRVRIILMSLSTTSDVKQLLLAVDFIEALLAVPYTNLQHRFTRLCRSLM
NILRCGIEEPAREAQRVLKRMLVTDSQFGAYHTPLRSFITKELRDNCKVALMRLYGRAQQ
ANVSFTPDFLSTMLAAEATAEISPRFITGTLRQQVLELASMLAGFSDLLLRRAAYRCMVV
LFKNTSAMRRKEVVLENRRIINEAIRSLNLSHNSESSIISTLETLRALLSSRGVHCMDKQ
VNTLPQLCVLVTEQHRISKTTAVRNAVCDLVPVIAETDISSAARRTTYCAIIMEPVKNVR
DDSNKDLELRNLAIFIQNVGYEVLDSTNRVNLDSIIQRYITRRGTEEECWHILAAICSSR
ARPETQRTHMCSKTSYIAMSSSSAMQKGCETIQGHQSGGEISLSAQELRSASAEAHSVCQ
LVAGESQNSCNSHELMQPVEALVRRCLPHMVHAVLSDEFVRYITIIQDHLPSLSSDLQTY
LDQLVNRTLRNDKRKYCGGEVEDGALVAQVFAGDRLSTELGNSQPQEDIIQSSTLAYVTA
MGRLAQYLLPTTLPEGGAINWQQSQGATSTTATDGNGQGYSLGSVETFCKSVVAGQPQLV
SPESTLSSAAGATTAEVCSGAAPDSVGASELKIALEVFSKRQITSSDQLREVSDIIIQYQ
RHPDKRVRQQCCTTVIEALKCWARYSQSDRTSAYSSLVPDLLEVYLKNVAMELDPKVRLV
EVTLLADAVELRMFLREKRIIDTLISFLHDISHVREKTMELLVTLAQDNHTGPSVETVQY
SLLIVVESSVAALEYSSDPRILIRHMSDLQTVAKFSLRPLMGHLDRTFVACRRRLVEEVV
PDTIALSTLKTLRTILEAIKREEAVLLKYKDVALELYAPVAVALRASTASPLSHAAIGVL
VCMHEIGASPLNWDARQLHELLQSVTAVYIEAANSTEEELGRALTLFGQIGAVDPATKPD
TAAMKKKDDEAAIQDEADLELTYDYTKIVYRNLSRMLDLSLSESVCVQSMCTLLHLVRLT
TDRKELIGGMHAIKAILQIARRANDAPLLRIEALHILAAITSLRHEKVCKTLLPELVTLF
EQLWYPQDHALFRAVLNLVSALKPGNLTGKEQSEVWPWLYPRLVDVALQDHTETREFCLR
VVGIIQHAKYIPPHCIPIVFPMLTQFVQQMDQLAELRSLSLCAAIRIVCNLQAVQHLPSL
MHTICTLTRHCDLTENLGPRLSTPTLHRSLRLLSNTHPNGEADVNALCERLCATGSEGSA
DAGGCFTNEGGETLPTSTQPNSSFHCGNGDYASAPYLGQYTQKCQQQQQGGTYLDPNDDE
AYDTLPQGQQDITAFMKHVEFGLRAKDNKWREWFAEFQKNMIVASPHPVFRIMVDLFDKH
EPLRRKLFHPSFKCFYESLNAEHMKKVKDVLNLALRSSDTEVVSKCIGLADYLDHNPPNI
SESVLQQLRHLEGNEPMDVGKFTKHSNLHVGNVIAGSRSPTPACRHEPGGYYASHHGQLY
RNISDNYNFESVLHSLNSPKTEGPVFNEGVRPPSHKVQDVGNGEHEVTDNGGTDSGCGVE
RNGKEGRSESESGDVNGSARRQTMLPVAKSIEGDTNEGLSFLAGPVARRITVSAHHTTNV
NASDGTCPNTGDAEVHIRATAIPSTVNPLFTNDSLVEAALRTRMPDKAMSYLENKLLPVM
QKYRYAHSVPKEAVQAVVLPLASLYSRLEMQDSVVGLFHAMRYKSDNEDGFAYELLQWWD
VAQGVYATKVHDCCGSSARDIDGYVRMLCLCGEWERALQVVKDTYKSLDQPSSTIAQSGA
MAAWILGKWDDVKMLIERLPNKEKGNITLRHFFQNATLFHQEFGCRAQWDCGVQDGQRRL
ETSPQVEALRASIMRAKMEVDESLKTLLPLSYAHAYENLTMLQHFTEMEEHIAYMESRTE
EFRGQLRERWNRRFAALKPDSLMPNLRSLMLHSLVLNASEMSVMVVNFCERTGTNYPQLS
KWAMEWLKQGKFPRANHLSQSCHVLPATPVSLEPCVAITYIGQVWSGGQRQKAVQLMENF
LEETHSTLEEQQPAAYGVAQLRLGMWKQEMFADSFWKVEHRQEVLRHFHEAVRAVPGSCE
AWHSWGLMNYRVQQRDCSLSRYEQRLFVEAAHQGFVAAICRSASPSTALPGVMRLLQLWV
FHNGMSLLKESVADSVARIPTDYWVQAIPQLIGHLRSASHDVRDVVSMILQRLCVAHSQA
VVFPLLVVLMSADGGGGETHSRRKELARSIINNLPKRIRAEAELVATLLINASATPIERI
GESLSAVATAWNPNAEYEEDKEEVRRKLRYVLDVFNTNRRQLLYNVGDIGQYVRIVMEED
ACGRREKASGILTQLVEEITKHISEKLGKEPQKAMEPLLNLRNLSIAVFGEYDIQYTNFP
TIASFSSKLDVIPSKKRPRRIRLSGSNGCMYTYCLKGNEDIRMDERVMQLFGMVNVLLSD
AKTAKSAFIHRFPVIPISDNVGLLGWVEHANTINNTICTHRNTISKVRTHHESNTLRAYV
ETIGSWEKLSMIRRTEILDYVMSQKDCEAVDVARAMWHRSNTAEQWLERRTAFTQSLATM
SMVGYVLGLGDRHLGNILLSMSTGKIVHIDFGDSFDVGRLRHVLPETVPFRLTRMLTNAM
EVFGVDGVFRASCNRTQSTLHKNADSIMALLTAFVHDPIVQHKGKMRNMMEKSRTPQNIV
ERIRNKLRGTEMAVRNADTVIFNTVLESSRRPDLLYMSHAFNDVAKRTVVNGRTTEEQVS
MLIDEATRLENYAALYFGWGPLW
NT seq
8712 nt
NT seq
+upstream
nt +downstream
nt
atgccgcgttacaccgccatgcgacgtctcggtccagtgggccatagcggtggaataagt
tcaaacggtgtcaccactgttggtgccgtcaccgcgagtaatgtcggtaacggcgttgtc
aacatcggcggagatggatctcagggcgttgcaatgggccccggtgcaacggatgtggct
tcggctcgcccgcttcttattgtaccaaacacaacctccgctgctggaggctccgcagac
gttagtgacgaggaggttgatcagttattaagggagcttgaacgctctgtcgatagtcca
caggcagctgcggttatgcgtgacgctgtgtgggctattgagcgacgtgcattttctagt
tgtgacccccatagtcgtgattatttcctcgagagtcgtgttcggattatcctgatgagc
ctgtcgacgacaagtgacgtaaagcagcttctgctggccgtggacttcattgaggcccta
ctcgctgtaccgtacaccaacctgcaacaccgattcacaaggctatgtaggagtctaatg
aacatactgcgctgtggtattgaggaaccggcaagggaagcgcagcgtgttttaaagcgc
atgctggtgactgattcgcagttcggtgcttatcacaccccgttgagatcattcattaca
aaggaactccgcgacaactgcaaggtggcgctcatgcggttatatggtagggcacagcaa
gccaacgtgtccttcacgcctgattttctctctaccatgctagcagcggaggcaacggca
gagatcagtccacggttcatcacggggacgcttcggcagcaggttctggaactggcaagt
atgctagcaggtttctctgatctgttgctccgtcgtgccgcctatcggtgtatggtggta
ttgttcaaaaacacaagcgcaatgcgacgcaaggaggtagtgcttgagaaccgccgaata
ataaacgaggcgatccgttcgcttaatttgagccacaatagtgagtcgagcatcatctcc
acacttgagacgcttcgcgccctccttagcagcagaggggtgcactgcatggacaagcaa
gtgaatacgcttcctcaattatgtgtacttgtcactgagcaacacagaatttcgaagaca
acagcagtgcgcaacgcagtttgtgacctcgtgcctgttattgctgaaaccgacatcagc
tctgctgctcggcgtacaacatattgcgccattatcatggagcccgtaaaaaacgtccgc
gacgattctaacaaagacctggagctgcgaaatctagcgatattcatacaaaatgtaggt
tacgaggtgttggactcaactaacagggtaaacttagactccattatccagcgctacatt
acgcgacgtgggacagaggaggagtgttggcacattcttgcggccatctgcagctcacgg
gcgagaccggagacgcagcgtactcacatgtgtagcaaaacaagttatatagccatgtcc
tcctcctccgcaatgcagaagggctgcgaaacgatccaggggcaccaaagtgggggcgag
attagcttatccgcgcaagaacttcgttcggccagcgctgaggcccattcagtttgccag
ttggtggccggagaatcccaaaacagttgtaatagtcacgagctcatgcaacctgttgag
gctcttgttcggcggtgtcttccccacatggtccacgccgttctttctgatgaatttgtg
cgttacatcaccatcatacaagatcaccttccgtcgttgagctcggacctgcagacgtat
ctcgaccaactagtaaatcgtacactgaggaacgataagcgtaaatattgtggcggtgaa
gtggaggacggcgctctcgtcgctcaggtatttgctggggaccgcctatcgacggaactg
gggaactctcagccacaggaagacatcatacagtcatccacattagcctatgtcaccgcg
atggggcgtttagcgcaatacttactacctaccaccctacctgaaggaggtgccataaac
tggcagcagagtcaaggagcaacaagtacgactgccactgatggcaatggtcaaggttat
agcttaggatcagtggaaaccttttgcaaaagtgtggtggctgggcaaccacaattggta
tcgcctgaaagtacacttagtagtgccgcaggagccacaacagccgaggtttgcagtggg
gcagcacccgactctgtgggtgcctcagagctcaaaatagcgctggaggtcttttcaaag
cgacagataacatcgagcgatcagctaagggaagtgagtgacattatcattcaataccag
cgacatccggacaagcgggtacggcagcaatgttgtacaaccgttatcgaggcactcaag
tgctgggcacggtactcacaaagcgaccgaacatcagcttattcaagcctggtgccggat
ctactagaagtgtacttgaaaaatgtcgccatggagttggatccgaaggtgcggcttgtg
gaagtgacactgctagccgacgctgtggagttgcgaatgtttcttagggaaaaacgcatt
atcgatacattgataagttttctgcacgatatatcgcatgtgcgtgaaaagaccatggag
ctgctggtgacgctcgcgcaagacaaccacaccggtccttcggtggagacagtgcagtat
agtctactcattgtggtggagtcttccgtggcggcgttagagtactcgagcgatccccgc
attctcattcgacacatgtcagacctgcaaacggtggctaaattcagtcttaggccgcta
atggggcatctggatcgtacgtttgtcgcctgtcgccggcgccttgtggaagaggtagta
cctgacaccattgcgttgtctacgctcaaaacgttgcgaactatactggaggccataaag
cgagaggaagctgtgcttctgaaatacaaggacgttgcattggagttgtatgcgccggtg
gcagtggctctccgcgcaagtaccgcctcgcctctcagtcacgcagcaatcggtgtttta
gtgtgtatgcatgaaatcggggcatcaccgttgaactgggatgctcgtcagttgcatgaa
ttgttgcagtccgtcaccgcagtatacatcgaggcggcaaacagcacggaggaggaactg
gggcgggcactcacactctttgggcaaattggtgcggtagacccggccacaaaacctgat
acagccgcgatgaaaaagaaagatgatgaggcggcgattcaagatgaagcggaccttgag
cttacctatgactatacaaagattgtttaccgcaacctaagtcgcatgctagacctgagc
ttgtcggaaagcgtgtgtgtgcagtcgatgtgcacattattgcatcttgtgaggctcact
accgaccgaaaggaactgattggtggaatgcacgccataaaggcgattcttcaaattgcc
agacgcgccaatgatgctcctttgcttcggattgaagcgctccacatactagcagccata
acttcgctgaggcacgagaaggtgtgcaaaacgcttttgccggagctggttacgctgttc
gagcagctgtggtatccccaagaccatgcactctttcgcgcagttctcaacctcgttagc
gcgctgaaaccaggaaacctgacaggaaaagagcaatcggaggtttggccgtggttgtac
ccgcgccttgtggacgttgccctccaggaccatacggaaacccgcgagttctgccttcgt
gtggtgggaatcatccagcacgccaagtatatcccacctcactgtattcctatcgtgttt
cctatgctcacgcagtttgttcagcaaatggatcagttggcggagctgcgctctctttcg
ctctgtgcggcaatccgaatcgtatgcaaccttcaggcagtgcagcacctaccctcgctg
atgcacactatctgcacccttacgcgtcactgtgaccttactgagaacctcgggccccgc
ctctccacaccgacgctacataggtcgttgaggctcctttcgaacacacatccgaacggt
gaagcggatgtcaacgcactgtgtgagcggttgtgtgccacagggagtgagggaagtgcg
gatgcaggtggttgtttcacgaatgaaggaggcgagaccttgccgacgtcaacacagcca
aactcgtctttccattgtggtaacggtgattacgcgtctgcaccatatcttgggcagtac
actcaaaaatgccagcagcaacagcaaggggggacatatttagaccccaacgacgacgaa
gcgtacgatacgctgccgcagggtcagcaggacataacggcatttatgaagcatgtagaa
tttgggctccgagcaaaggataacaagtggcgcgaatggttcgcagagtttcagaagaac
atgatagttgcctctccgcaccccgtcttccgtattatggtagacctctttgataagcac
gaaccattgaggcgaaagctgttccatccatcctttaagtgtttctacgagtcgctgaat
gccgagcatatgaagaaggtgaaagatgttctcaaccttgccctcaggtcaagtgatacc
gaggttgtgtccaagtgcattgggcttgcggactacctcgaccataacccaccgaacata
agtgagtccgtgctacaacaactgcgtcatctggagggcaatgagcctatggatgtgggt
aagttcactaaacatagcaatttgcacgtcggcaacgtgattgctggaagtagaagtcca
acacccgcctgtcgtcacgaacctggggggtattacgcctcccaccacggccagctttac
agaaatatcagtgataactataattttgagtctgtgttgcactcactcaattcacccaaa
acagaagggcccgttttcaacgaaggcgtacgtccgccttctcataaggttcaggatgtg
ggtaacggagagcatgaagtcactgacaacggggggaccgacagtggatgtggcgttgag
cggaatggtaaggaaggtagaagtgagagtgaaagtggtgacgtcaatggaagcgctcgc
cgccagaccatgttacctgtggccaagtcaattgagggtgataccaacgagggtctaagt
tttctcgctgggccagtcgcgaggcgcataacggtatccgcacatcacaccacaaacgtt
aatgcatccgatggcacttgccccaacaccggcgatgcagaggttcacattcgtgccaca
gccatacccagcacagtcaacccactgtttacaaacgatagcctcgtagaggctgccctt
cggacgcggatgcctgacaaggctatgagttatcttgagaacaagttactcccagttatg
cagaagtatcgctacgcccacagcgtacctaaggaggctgtgcaggcagtcgtcctccca
ctcgcctctctctacagtcggctcgaaatgcaggactcagtggtcgggcttttccacgcg
atgcgttacaaaagcgataatgaagacgggtttgcctatgagttattgcagtggtgggat
gtggcacaaggcgtgtatgcaaccaaggtacatgattgctgtggaagttcggctcgtgat
attgatggttacgtgaggatgctttgtctgtgtggagagtgggagcgcgctctgcaggtc
gtgaaggacacctacaaatccctcgaccaaccatcgtccaccattgcgcagtcgggtgcg
atggcagcgtggatccttggtaaatgggatgacgtgaaaatgttgatagagcggcttcca
aacaaagagaagggaaatattacgcttcgacacttctttcaaaacgccacgcttttccac
caagagttcggttgccgggcacaatgggattgtggggttcaggacgggcagaggcgcttg
gagacttcgccccaggtagaagccctccgcgcgtctatcatgcgggcgaagatggaggta
gatgagagccttaaaacgttgttgccactcagttacgcgcacgcatacgaaaatctcacc
atgttgcagcacttcaccgaaatggaggagcacattgcctacatggagtcgcgaacggag
gagtttcggggccaacttcgggagcgttggaaccgtcgcttcgctgcactgaagccggat
tcgcttatgcccaacctacgctcccttatgctccactcgcttgtgctaaatgcgagtgaa
atgtccgtgatggttgtcaacttctgtgagcggactgggacgaattaccctcaactgtca
aaatgggctatggagtggcttaagcaaggcaagtttcctcgtgccaatcatttaagtcag
tcgtgtcacgtactccctgctactccggtcagtttagagccgtgtgtggccataacatac
attggccaagtgtggagtggcggtcagcggcaaaaggcagtgcaactgatggagaatttc
ctggaggaaacgcattctacactggaagagcagcagccagctgcctatggtgtcgcgcaa
cttcgtttaggtatgtggaagcaggagatgtttgcagattctttttggaaggttgaacac
cgccaggaagttttacggcacttccatgaggcggtacgcgccgtgcccggaagctgtgag
gcgtggcatagttgggggttaatgaactaccgagtgcagcaacgcgattgctcactatct
cgttatgagcagcgcctcttcgtcgaagccgcgcatcaggggtttgttgcggctatctgc
cgcagtgcaagtccctctactgctcttcctggcgtgatgcgtctgcttcagttgtgggtt
ttccataatggaatgtcattactgaaggaatcggtggcagacagcgtcgcccgaatcccc
actgattattgggtacaggcaattccgcagctgatcggtcacttgcgcagcgcaagccac
gatgtacgtgacgttgtgagtatgattcttcaacgactgtgtgttgcacattcccaagct
gttgtttttccgctgttagttgtgcttatgtccgctgatggcggtggaggggagacgcac
tctcgtcggaaggagttggcgcgatccatcattaacaatcttccgaagcgcatccgcgct
gaggcggagttagtagccaccctcttaattaatgcatcggcgactcccattgaacggata
ggggaaagtctcagtgcggtggcgacggcatggaacccgaacgcagagtacgaagaagac
aaggaagaggtacgacgaaaactaagatatgtgcttgatgtgttcaatactaaccggcgt
cagctgctctacaacgtgggtgatattggccagtatgtgaggattgtcatggaagaggac
gcgtgcggccgcagggagaaggcaagtggcattctcacccaactagtggaagaaatcacg
aagcacatttcggagaaactgggaaaagagcctcagaaggcgatggaaccgctactgaac
ctccgcaatctttcaatagcagtgtttggagagtatgatattcagtacaccaactttcct
actatcgcgtcgtttagttcaaagcttgatgttattccctctaagaagcgtccacgccgc
atccgcctcagcggctctaacggttgcatgtacacatattgcctgaagggaaatgaagat
atacgtatggatgaacgggtcatgcaactgtttggtatggtgaatgttctattaagtgat
gccaaaaccgcgaagagtgcattcatacaccgcttcccagtaatccccatcagtgataac
gttggcctgctcggttgggtagagcacgcgaacaccatcaacaataccatctgtactcac
cgcaacaccatttcaaaggtacgaacgcatcatgagtccaacacccttagggcctatgtt
gaaaccatcgggagttgggagaaactcagcatgatacgtcgcacagaaatactggactac
gtcatgtcgcagaaggattgtgaagcagtggatgttgcgcgtgccatgtggcatcggtca
aatacagcggagcaatggttggagcgccgcacggccttcacgcagtcgttggccaccatg
tcgatggttggttacgtgcttgggcttggggatcgtcatctgggcaacattctcctttcg
atgtccactggaaaaatcgtacacatcgactttggtgacagctttgatgtcggtcggttg
cgccatgtacttccagaaaccgttccattccggctcacgcgcatgctaacgaatgcaatg
gaagtgtttggtgtggacggtgttttccgcgcctcatgcaaccgcacacagtcaacgctg
cacaagaacgcagacagtatcatggcgcttctcaccgctttcgtacacgaccccattgtt
cagcacaaggggaaaatgcggaacatgatggagaagagccgcaccccgcagaacattgta
gagcgcatacgtaacaaacttcgtgggacggaaatggcggtgaggaatgctgatacggtg
atatttaacacggtactggagagttcacgaaggccggaccttctctacatgtcacatgcc
ttcaatgatgttgcgaagcggacggtggtgaatggacggacaacagaggagcaggtgtcg
atgttaattgatgaggcgacgcgattggagaattacgccgcgctctactttggatgggga
ccgctgtggtga
DBGET
integrated database retrieval system
