KEGG   Trypanosoma brucei brucei: Tb11.02.5720
Entry
Tb11.02.5720      CDS       T01013                                 
Name
(RefSeq) ribonucleoside-diphosphate reductase large chain
  KO
K10807  ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
Organism
tbr  Trypanosoma brucei brucei
Pathway
tbr00230  Purine metabolism
tbr00240  Pyrimidine metabolism
tbr00480  Glutathione metabolism
tbr01100  Metabolic pathways
tbr01232  Nucleotide metabolism
Module
tbr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
tbr_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:tbr00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    Tb11.02.5720
   00240 Pyrimidine metabolism
    Tb11.02.5720
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    Tb11.02.5720
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:tbr03400]
    Tb11.02.5720
Enzymes [BR:tbr01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     Tb11.02.5720
DNA repair and recombination proteins [BR:tbr03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    Tb11.02.5720
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_lgN ATP-cone
Other DBs
NCBI-GeneID: 3665440
NCBI-ProteinID: XP_828859
UniProt: Q384N4
LinkDB
Position
11
AA seq 838 aa
MLETVKLVTKRDGSVEPYDEKVVRSRIVNLMSGIDSYYVDVDDLVRVVGEGVREGMSTSM
LDELLAETAAYCVTKHPDYGLLAGRLAVTALHKTTTESVLDSFRVLHEHVSQATRRHAPL
ISEELWDIANKHSAALQQIINYERDFDFEYFGYKTLERSYLLRVDKGRGVMEVVERPQQM
FLRVALGIHGEDLERVKETYDYMSQGFFTHATPTLFNAGTPFPQMSSCFLVAMREDSIDG
IYDTLKQCAIISKSAGGIGIHMHNIRAAGSYIAGTNGTSNGLVPMLRVWNNTARYVDQGG
GKRKGAFAIYLEPWHADIFGFLLLKKNTGKEDQRARDLFYGLWIPDLFMERVESHGTWTL
MDPNTAPFLSDCYGQEFTDLYERYEREGRGVRTIQAQELWFLILESQVETGVPFMLYKDA
CNFKSNQKNLGTIKCSNLCTEIVEYTSRDEVAVCNLASIALPRFVKDGAFDYVALKEVTK
VVTRNLNRVIDRNHYPVREARYSNLRHRPVGIGVQGLADTFALLSLPFAHPEAKKLNRQI
FETIYFAAVEASTELAEKDGPYETFKGSPASEGKLQFDLWDEERRIRGMNEDSVHSHCGL
WDWDSLKERVVKVGMRNSLLVAPMPTASTSQILGNNECIEPFTSNIYVRRVLSGEFPVVN
KHLVKELIRLQLWNDDMRRKIIALNGSVSGIKEIPERIRELYKVVWEIRQKDLIDMAADR
GRYIDQSQSLNLFLGTPTSSQLTSMHFYSWKKGLKTGMYYLRSQPAADAIKFTLDPKAMK
ELPKPDKQSKEEVHGSVGRGKRKRAGEKPTANHSNAGAPNLNGPPDTDGDGGCLNCGS
NT seq 2517 nt   +upstreamnt  +downstreamnt
atgttggaaacggtgaagcttgtgaccaaacgtgatgggtctgtggaaccgtatgatgaa
aaagtcgtgcgcagccgcatcgtcaaccttatgtccgggattgattcttattatgttgat
gttgatgaccttgttcgtgtagtgggggagggggtgcgggaaggtatgagcacctcaatg
ttggatgaactgctggctgaaactgctgcttattgcgtaacaaagcatcccgattacggt
ctgctggctggccggttggctgtaacagctttgcacaagacgacgacagaaagtgtactg
gattcttttagggtgctacacgaacatgtttcgcaggcaacgaggcggcatgctcccctt
atatcagaagaattgtgggatatcgcaaataagcactctgcggcgttgcagcaaatcatt
aattacgagcgggattttgattttgagtatttcgggtacaagacacttgagcgttcttac
ctccttcgtgtcgataaggggcggggagttatggaagtggtggagcgtccacaacagatg
ttcctgcgtgttgccctcggtatccatggagaggacttggaacgtgtgaaggagacatat
gactacatgtcgcaagggttttttacccacgctactccaacgttattcaatgcggggacc
ccattcccacaaatgagttcatgctttcttgtagctatgcgtgaagacagtattgatggc
atctacgacacactcaaacagtgtgcgatcatcagcaaatcagctggtgggatcgggatc
cacatgcacaacattcgcgcagcggggagctacatcgccgggacaaatggtacgtcgaat
ggtctggtccccatgcttcgtgtgtggaataacactgctcgctatgttgaccagggcggt
ggcaagcgcaagggcgcctttgctatttatttggagccctggcacgcggatatctttggt
ttcctccttctgaagaaaaatacgggcaaggaggatcagcgtgcgcgggacttgttttac
ggtctgtggattcctgacctgtttatggaacgagttgagagtcatgggacttggacgctt
atggaccccaacacagccccctttttgagtgactgttatggccaagagtttactgattta
tatgagcgatatgaaagggaaggtcgtggcgtaagaactattcaggcccaggaactgtgg
ttccttatccttgagtctcaggtggaaacgggggttccttttatgctttacaaggatgca
tgtaatttcaagtctaatcagaaaaatctcggcacgataaaatgctcaaatttgtgcacg
gaaattgtcgagtacacttcgagggacgaggtggccgtatgcaacctagcctctattgcc
cttccgcgttttgtgaaggatggcgcatttgactacgttgcattgaaggaggtgacaaag
gttgtgaccagaaatcttaaccgggtgattgatcgcaaccactatccagtgcgtgaggcc
cgatacagtaatttgaggcatcgccctgtgggtatcggtgtccagggactggcggatacg
tttgcactgctttccctgccattcgcacaccccgaggcaaagaagttgaatagacaaatc
ttcgagaccatttactttgcagctgtggaagcaagtacggaattggctgaaaaggacggg
ccctatgaaacgtttaaaggaagccctgcttcggaagggaaactgcagtttgatctgtgg
gatgaggagcgtaggataagaggtatgaacgaggactctgtgcattcacactgcggactc
tgggactgggatagcctcaaggagcgtgtggtcaaggttggtatgcgtaactcgctgtta
gttgcgcccatgccaacggcatctacgtcgcagatccttggtaacaatgagtgcatcgaa
ccctttacttccaatatctacgtgcgccgggtcttaagcggggagtttccagttgtaaac
aaacaccttgtaaaggagctcattcggcttcaattgtggaacgatgatatgcgaagaaag
attatcgcattaaatggctctgttagcggcatcaaggagataccggaacggatcagagag
ctttacaaggtcgtatgggagatccgacagaaggatttgattgacatggcagccgaccgg
gggaggtatatcgatcagagccagagcctaaatctctttctgggaacacccacctccagt
caactcacttctatgcatttctattcgtggaagaaaggccttaagaccggtatgtattac
ttacgctctcaacctgccgctgatgccatcaaatttacactcgaccccaaggcaatgaaa
gaactgccgaagccggataagcaaagtaaagaggaagtacacggaagtgtgggccgagga
aaaaggaagcgggctggggagaagccgacggcgaaccattcaaatgctggagctcctaat
ctcaacggacccccagacacagacggtgatgggggatgcctgaattgtggttcgtag

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