Telmatherina bonti: 306759074 Help Entry 306759074         CDS       T12083                                  Symbol hmcn1 Name (RefSeq) hemicentin-1   KO K17341   hemicentin Organism tbt  Telmatherina bonti Brite KEGG Orthology (KO) [BR:tbt00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:tbt04990]     306759074 (hmcn1) Domain-containing proteins not elsewhere classified [BR:tbt04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    306759074 (hmcn1) SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig Ig_VEGFR-1-like_5th V-set C2-set_2 VEGFR1-3_N_Ig-like Ig_SEMA-3_4_7A TSP_1 EGF_CA VWA_4 G2F Ig_PDGFR_d4 C2-set_3 cEGF TSP1_spondin V-set_CD47 Receptor_2B4 GBD_Hemicentin FXa_inhibition TSP1_CFP_C EGF_3 EGF TSP1_ADAMTS hEGF TSP1_CCN Coilin_N VWA7_4 Fibulin_C Motif Other DBs NCBI-GeneID:  306759074 NCBI-ProteinID:  XP_079100693 LinkDB All DBs Position 8:complement(13739284..>13822421) Genome browser AA seq 5628 aa AA seqDB search MGSRLMWLSLVLSAAFCVGQDGSSRGPSEDIPEGASTLAFVFDVTGSMYDDLVQVIEGAS KILETSLSRPKRPLYNFALVPFHDPEIGPVTITTDPVKFQNELRELYVQGGGDCPEMSIG AIKIALEISLPGSFIYVFTDARSKDYKLTHEVLQLIQQKQSQVVFVLTGDCDDRTHIGYK AYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQSSKVHLLSTDHFSQVSNTWQMPFDPSL KEVTVALSGPAPDIEIKTPQGKLVEKNDGLTELLHIPNSAKVVNIKDPQPGMWSIKASSK GRHSVRITGLSTIDFRAGFSKKPTLDFKMTSSRPVQGIPTHILLNTTGLSPPARPDRLEL LTITGEVMKTLPIRYYPERQLYNLWNITEFIPPKEAFFLRVTGYDRDGFLFQRVSSVSFS SITPNAPKVVMPATTNGYYLQRGAIGCQVESLIPFTLRFSRDGRQLGVDQLFSESDDASW EISQVTLKDEGYYECIAISSAGTGRARTFLDVSEPPPAITVQGNVTVSPGSPAVLTCHVV STVSFNITWLRGGHDARQDPRVNILANLSLQVSAVTPDHSGWYDCIAANEGGATADRIYL TVQAVPRVSVEPRNQTFMKGDDVRIRCSASGFPQPSRVWTHNDMFIMASSRHRMTPDGTL VIRNMERKDEGVYGCLASNQAGTDTMTSVLTYLESPVVTVALSEVLVEIGETITMTCSAS GVPQPEIWWYKGTIQLHSSPLLEVDRWGGTLTTKQAQISDAGDYTCVAINAAGTSSGKIF LDVGAAPKFTREPSDVAADISSNVTLLCHVQGHPEPQVTWRREDGSPLFNRLRLHGSISQ RRGELHIINLWVDDEGVYICEAQNHFGKIKTQASITVTGLVSPVIAVSPAVLSVIEDQQV TLPCVLLAGNPLPERQWLHNYGLVTSDQYVTVRRDGSLHIERVRLDDAGDYTCLAENVVG ATNQTTTVNVHVIPTIQYGPQVFSTIEATTISLPCRASGVPNPDITWTKGGELLNLGGPA FTLDSDGSLVITSPSGNETGEFICTATNAAGSATRRVQLTVYVRPRPSAGGAAGGAGGSV EPVKMTVIEGQDAVLPCEVHSIPPPTISWAKEKQLISPYSPRHTQLPSGSMKILETRVSD SGLYICVASNIAGNLTLSTQLSVLVPPRIQAGPRVMKVQVSHPVELLCVVRGIPEPTVTW TKEDKSYPVLPDGSLALKNVGLEDEGTYTCTATNPAGRDDAHVTLVVQVPPVVEVLEPPF NSPLQERVANQRIAFPCPAKGFPKPVIRWLRNGQELTGNEPGVSILEDGTLLILASVSPL DDGEYVCTAANDAGSTVRKYQLKVNVPPGFRDSDMPGNLSVVLNQPTSLVCDATGSPTPV ITWYKHGTPVVASNSIQILDMGKTLRLLKAETADAGSYSCKAINIAGSSEKDFFLHVLVP PTIVGSGSPQDVSATHKQEITLECKVQGSPFPTIQWYKDRKLVFLGDPNLNVTNRGQVLK IKSARLGDQARYQCSVMNAAGKQSKDFNLRVYVPPSIKGGNLTTEVTALLDTMVTLECEA RGVPLPTITWYRKGEVILSNRQAQYVERGHYLKIPRVQASDAGQYICKVTSVAGSAERSY ELDIYMPPTIVGGDDEPTERTVVLTKPLILECEAEGHPPPSLTWLKDGVPVRDGESVRVL EQGKKIEILSAMASDSGRYICVATSIAGEKEVKYDVRVLVPPFIVGAEDVTDRIVIINSL LELECDATGTPAPVIKWYKDGKPVRQSEGLRIAASGRQLLVSRAQISDTARFQCVATNEA GDHKKDFNVVIQVPPSIRTTGPAERSVVFGKSIGLECISSGIPPPSITWLKDGRPIDTTK KHLKLQSAGRTLKITEARLEDSGRYTCLSTNAAGEAQQHIQLSVHEPPRIPLSGEIINQT ILSGFSTELECKASGSPLPAITWYKDGRPLTGAAGVSMLKRGQVLEIERAQLSDAGMYKC VAVNLAGAAEIFYSLQVFVPPIISSRGGTVTVVVNEVARLECEASGVPIPSLTWLKDGSP VASIAHGIQVLSGGRVLMLNSAQVSDAGRYTCVVVNAGGEQQREYNLNVYVPPNIKGEEV NATVMLGHPVELHCQSDAIPPPRLLWRKDGRQLFRKPGLTVSADGSLLKVDSAQVQDAGR YTCEAINVAGKTEKNYNLNVWVSPSIRGSHEVSPLTVIQGGLITLVCESSGIPPPNLTWR KDGSELKLDQRLKVISGGRQLQISTAERSDTASYTCTASSASGTASKEYSLQVYVRPSIR YTDGDSDDVTVTKGSDVTLQCVAEGVPRPAITWLKDGRPITGHHVAKILNEGRLLQIKDA KVSDTGRYTCIAVNVAGQADSKYDISVHVPPSIIGQVQFPENVSVVVKNPVALSCEASGV PLPAISWLKDGQPVKATGSVRILSGGRSLRLMHAAVEDAGRYICIVSNSAGEERKNFDLD ILVPPSIVGEGTVVDTKVKEKHNITLTCETSGNPVPEIKWLKDGQLLLPDRRHQVLSHGR FLQISESQVADTGRYSCLASNSAGDRSRHFNLNVLVSPTIAGTGPDISPEEVTVTLSSPT SLVCEVQSYPPALITWLKDGTPFESTRTVRVLPGGRTLQILNAKEEDAGRYTCVATNEAG ETLKHYEVKVYVPPQINKNDIPGEGLAPKEVKIKINSTLTLECVAQAFPTPALQWYKDGQ ILQTDDHVSITANGRIVQIKHAQVSDTGRYTCIATNIAGEDEKDFDVNIQVPPNFNRPGG VGDTISASGFGGDARDVILNNPISLYCETNAVPPPTLTWYKDGQLLTSNAKVLILPGGRV LQIPRAQIEDSGRYTCVAINEAGEDSIQYDVRVLLPPTIRGTNSDVPDEVTVLVNKTTQL ECHVDGNPSPKITWFKDSQPISSKDSYRILSNGRTLKMLTAQLSNTGRYVCVAENVAGSA EKHFNLNIHVPPTIIGVSYDNVTVVVNNFVSLSCEATGFPPPTLSWLNDRGPIQANSNAL IVPGGRTLQILKAKVSDGGKYICVALNAAGEAYKHIYLTVFVPPSIRGSNRDSPVVISVL VGKSVTLECESNAIPPPTITWYKNGRVVTETANLNIQAEGRILEISGSEVTDTGQYVCMA TNVAGQVDKNFHLNIHVLPSIDGPAEESVVETISNPISFACDATGIPPPSLTWLKNGHPI ENSDSLEMHIFSGGSKLQIARLQLSDSGTYTCLASNIEGKTQKSYHLTIQVPPRISGSEM PSEMGVLVNESTQLICQVQGTPTPLIQWLKDGEAINNMGDNRFRVSPDGSTLVLTRAHPE DSGKYTCVATNTAGEEDRIFNLNVYVPPAILGNSEAAEDLITVLDSSVSIECVAAGSPLP QLHWLRNGLPLPVSSHIRLLSAGQVLRITRIQVSDGGSYTCVASNRAGVDNRQYNLQVHV PPGLDGAGSTEDVTVVRGNLASLLCIADGTPAPDISWFKDEVALAPDHHISFLKLNSTLQ IIQAQINNTGHYTCMANNTAGQASRYFNLKVLDPPHIEGSGETSEVTVVVNNVLELQCEA TGIPPPSLTWLKDGRPLPQTDSLRLLRGGEVLRVASAQLEDTGRYSCLANSPAGDDDKEF LVRVHVPPNIAGESTPQDVSVLQNRQVTLECKSDAVPPPTLTWLKDGKPLQASARVRVLS AGRYLQINVAELSDRAQYTCVASNIAGKTTRQFNLTVNVAPAIKDGPQMVSVHVDKPAVL ECIVNGVPPPQVTWRKNGVILAGNNPRYTFVEDGSLHVHSAQVTDTGRYLCMATNQAGTQ RKRVDLQVYVPPSIADSRTNVTVIVNVQTTLSCEATGIPKPSVSWQKNGRTINTDQNQNM YRLLSSGSLVIIAPTVEDTAVYKCAVSNEAGNNSKSVNLAVIVPPSIADESTELVVTRLS PVVIACTASGVPKPTIHWSKDGVNLNKKGEGYSILPTGPVEIPSAELSHAGRYSCRATNS AGSTHRHVQLTVQELPVMQLHPATLDVIINSPFTLPCRATGTPRPTITWQKEGINLSTTG GGFTVLPNGSLQISKASLSDSGTYICVAQNPAGTALGKTKLRVQVPPVIHSEMEGYVAPV DSSVTLQCQAEGSPPPSVTWHKDGQLLSDSVRQRALSSGSLQITFIQPSDAGLYTCTAAN AAGSMSLDMGLIVLIPPSIRGGEQEVVAVENSHVQLVCAAEGIPQPTLSWEKDGIPCSEG VGEYTILPSGELVIDSAQPDDAGSYTCVAVNSVGQDSWTVTLSVHTHPVFTELLGDVALN KGEQLVLTCSVSGIPLPRITWAFNNNIIPVHYDQMNGHSELKIERVSKDDSGTYTCLAGN SVGTIKSLGFVYVKEPPIIDGDVHANRIEPLGGNAILNCEVRGDPLPTIQWSKNGINIQI TNRIRQLDNGSLAIYGTVSEDAGSYMCVATNDAGVVERSVTLTLQSAPTIVVEPVGTVVD AGTTVVLSCQAEGEPKPMIEWARQGRPLLVNEHFSTLSNGSLRISSAQKEDTAEYECVAR NLLGSVLVRVGLTVRVHGGYSEWAEWGHCSVSCGVGMQKRLRECNNPLPANGGRHCVGSD METRSCHGKPCPVDGNWSEWSSWEECSRTCGQGNRTRVRTCSNPPAQHGGIPCEGKAVEV IMCSVRPCPVAGNWGSWLPWSPCSETCGKGMQSRIRLCNSPPPAFDGPRCEGTDTQSQVC REKPCPVDGKWSSWMSWGACSVSCGGGTRQRTRLCASPAPQHGGRKCEGNDVLIDFCNSD PCPINGNWGPWSNWGSCSKTCNGGQTRRYRTCDNPRPAYGGRACAGADTQIQRCSTANCP VDGNWGLWQPWGECSASCGGGEKTRVRLCNNPSHSNGGRACPGDSTQLSRCNSQACPGGP LKARGSIIGNINDIEFGVSLLNATITKTNFGNRLIKATISNVPRTLGPAMRKLISILNPI YWTTAQEVGEAVNGYTLTGGIFRRETQVEFATGEILRMAHIARGLDSSGALLLDIVVNGH ILQLPSHADINIKDYSEDYIQTGPGQLYALSTCMFTIDEESVPYSWNHTITYDPAKGKMP YLVETLHATDITAHYNPLEEVLEYSIQANIAKGDRSNQCPHGFTLVAAGPYCADENECEV GNPCSHTCHNAVGTYYCSCPLGLTISADGRACQDIDECSLVGNLCHDGQDCENTIGSYRC VMRCGRGFRRTADGLSCTDVNECQESNPCNQLCLNTIGSYRCACEPGFQLKNRRCIDINE CRQRVCRSDQQCKNTRGGYTCIDLCPNGMTKGGNGTCVDVDECQDGTHQCRYNQICENTK GSYHCTCSRGFRSQGVGQPCVDINECERLPQPCAHQCINTPGSFKCTCPPGRHLLGDGKS CAGLERLPSYESYSYGYRTSQSSPEHRSNHQLYHNLASQSYHSYTSTRGGRSRSRSRRET RKHSSQQGVLTCQEGFEPRGGRCLDINECEVRDTCQHECMNTPGSYRCLCPAGYRLMANG KTCQDIDECLEQNIQCGANRMCFNMRGSYQCIDTPCPPNYHRDPTTGFCLKDCPANDLEC ALSPYALEYKLLSLPFGIAVNQDLIRLVAYTQDGVMHPRTTFLVVDEDVTLPFALRDENM KGVLFTTRPLREPHTYRMKVRALSYSEDGGIEYQTTFIVYIAVSAYPY NT seq 16887 nt NT seq  +upstreamnt  +downstreamnt atggggagtaggttgatgtggctgtcgcttgtgttgtcagcggctttctgcgtggggcag gacggaagcagccgtggccccagcgaggacatcccggagggcgcatccaccctggcgttc gtgtttgatgtgaccggatcgatgtacgacgacttggtccaggttatcgagggtgcgtcc aagattttggagacatccctgagcagaccgaagagaccattgtacaactttgccctggtg cccttccatgacccagagattggaccagtaacaatcacaacagacccagtaaaattccag aatgaactgagagagctgtacgttcagggaggtggtgactgtccagagatgagtatcggt gccattaagatagctttggagatctctttgccaggatccttcatttacgtcttcacagat gcccgctctaaagattacaagctgacacatgaagtcctgcagctcatccaacagaaacag tcacaggtggtgtttgtgttgaccggcgactgcgatgataggactcacattggttacaag gcatatgaagagattgcatctacaagctcgggccaagtcttccatctagacaagaagcaa gtgaatgaggttcttaaatgggtagaggaggcggtgcagtcctcgaaagtccacctgctg tccactgaccatttcagtcaggtcagcaacacttggcagatgccctttgaccccagccta aaggaagtaactgtggctcttagcggcccagcgcctgacatcgaaataaaaactccccag gggaagcttgtggagaagaatgacggcctaaccgagctcttgcacattcccaactctgcc aaagttgtcaacatcaaggacccacaaccagggatgtggtctatcaaggcttccagtaaa ggaagacactcagttcggatcacaggtctcagcaccattgacttccgagctgggttttcc aaaaaacccacgctggatttcaaaatgacatccagtaggccggttcaaggtattcctact cacatccttctgaacaccactggactgtcccctcctgctcgccctgacaggctagaactc cttacaataacaggtgaagttatgaagactttgcctatccgttactaccccgagcgtcag ctatacaacctctggaacatcacagagttcatcccacccaaagaggctttcttcctgcgg gtgacaggatacgaccgggatggttttctgttccagagagtctccagtgtttctttctcc agcattacacccaatgcacccaaagtggtgatgccagccaccactaatggttactacctc caaagaggggctattggatgccaggtcgagagtttgatacccttcactctgcgcttcagc cgggatggaagacaacttggagtggaccaactcttcagtgagtctgatgatgcatcatgg gaaataagccaggtaacgctgaaggatgaaggctactatgaatgcattgcaatcagcagt gctggaacaggacgagctcgcaccttcctggatgtgtcagagcctcctccagccatcaca gtccagggtaacgttaccgtctcccctggctcacctgccgtcctcacctgccacgttgtt agcactgtcagtttcaacatcacctggcttcgaggaggccacgatgcccgccaggatcca cgggtaaacatcctggccaacctttcgctgcaggtgtccgctgtaacgccagatcattct ggctggtacgactgcatcgctgcaaacgaaggaggtgcaactgcagaccggatctatctc accgtgcaagcggtgcccagggtctcagtggagccgcggaatcagacctttatgaaaggg gatgatgtgaggatccggtgctcggccagcggttttcctcaacccagccgggtttggacc cacaatgatatgtttatcatggcatccagcagacacaggatgactcctgatggcactttg gttataagaaacatggagaggaaggatgaaggagtttacggctgcttggccagcaaccag gctggtactgacacaatgacttccgtcctcacatatcttgaatctcctgttgtgacagta gctttaagtgaggttcttgtggagattggagaaaccatcaccatgacctgttcagcatct ggagtccctcagcctgagatctggtggtacaaaggtaccattcagctgcattcgtcaccc ctcttagaggtggacagatggggagggacactcaccactaagcaagcccagattagtgat gctggagattacacttgtgttgccatcaatgctgctggcacctcatcaggaaagatcttc cttgatgttggagctgcacccaaattcactcgcgagccgtcagatgtggcagcagacatc agctccaatgtgaccctgctgtgtcacgtccaaggacatcctgagccacaagtcacttgg aggagagaagatggctccccactttttaacagactgcgcttacatggcagtatatcccag aggaggggagagctacatatcattaatctttgggtagatgatgaaggagtgtatatctgt gaggctcaaaaccactttgggaagatcaaaacccaggccagcatcactgttaccggactt gtttcacctgtcattgcggtgagtccagctgtgctcagtgtgatcgaggatcagcaggta actcttccctgtgtgctgctggctgggaatccgctccctgaaagacagtggctacacaac tatggcctggtgacctcagaccagtatgtaacagtgaggagggatggcagtctacacatt gagagagttcgactggatgatgcaggcgactacacatgtttggctgagaatgttgtcggg gcaacaaaccaaacaaccaccgtcaatgtccacgttattcctactatccagtatggcccg caggtatttagcactatcgaggcaacgactatatctctgccatgccgtgccagcggtgta ccaaatcctgacatcacttggaccaagggtggagagctgctgaacctgggtggtccagct ttcactctggattctgatggcagcctcgtcatcacttctccttctggaaatgagacggga gaatttatctgcacagctacaaatgctgcaggctctgcaaccagaagggtccagctcaca gtctacgtccgacccagacccagtgccggtggtgctgctggaggagctggaggctcagta gaaccagtgaagatgacagtgattgaagggcaagatgctgttttgccctgtgaagtccac agtatcccacctccaaccatcagctgggcgaaagagaagcagctcatctctccttactct cccagacatacacagctaccatctgggtctatgaagatcttggagaccagagtgtccgac agtgggctttatatttgtgttgcttccaacattgctggtaacctgacactttccacgcag ctgagtgttttggtacctcctagaattcaggcgggcccaagagtaatgaaggtacaggtg agtcaccccgtggagctgctctgtgtggtgagaggcatcccagagccgactgtcacctgg accaaggaggataaaagttacccagtgttgcctgatggtagcctggctctgaagaatgtg ggactggaagatgaaggaacgtacacgtgcacagccacaaatccagcaggcagggacgat gctcacgttacgcttgtcgtccaagttcccccagttgttgaagtactggagccccccttc aacagccccctgcaagagcgagttgccaaccagcgcattgcttttccttgtcctgccaaa ggttttcctaaaccagtgattcgttggttacgtaatggtcaagaacttactgggaatgaa cccggtgtgtccattctggaggatggtacgctgctgattcttgcctcagtctcacctctg gatgatggggagtatgtttgtacagctgccaatgatgctgggtccactgtgagaaagtac cagctgaaagttaatgttcctccaggtttccgggacagtgacatgccaggcaacctgtct gtggtcctgaaccagcccaccagcttggtgtgtgatgccacaggaagtccgacccctgtc atcacctggtacaagcatgggactcctgttgttgccagtaacagcatccagatccttgat atgggaaaaaccctgagactgctgaaggcagaaacagcagatgcaggcagctacagctgt aaggccatcaacattgcaggcagctctgaaaaagactttttcctgcatgtcctagtcccg ccgacaattgtaggttctggttctcctcaagatgtttccgcaactcacaaacaagagatc actcttgagtgtaaagtacaagggtcaccgtttccaacaatccagtggtacaaggacagg aagcttgtgtttcttggtgatcctaatctgaatgtcaccaaccgcggtcaggtgttgaag ataaaaagtgcccgtctgggagaccaggctcgctaccagtgtagtgtcatgaatgcagcg ggaaaacagtccaaagattttaaccttagagtctacgtgcccccttcaatcaagggaggc aatttaaccacagaggttacagcactgctggacacaatggtaacactggagtgtgaggca cgcggagtgccacttcccaccatcacctggtaccgaaaaggagaggtcatcctgtccaac cgacaggctcagtatgtagaacgaggccactatctgaagatcccacgggtgcaggcgtct gatgctggtcagtacatctgcaaggtgaccagtgtggccgggagcgcagagaggagctat gagctggacatctacatgcctccgacgatagtaggaggggatgatgagcccactgagagg acagtggttcttactaaacctctgatcctggagtgtgaggcggaaggacaccctccgccc tccctcacctggctgaaagatggagtccctgtgcgcgatggggaaagtgtccgtgtgctt gagcaaggcaagaaaatagaaatcttgtcagccatggcctctgactcaggacgctacatc tgcgtggccacaagcattgcaggagagaaggaagtcaaatatgatgttagagttttagtt cctcctttcattgttggagctgaagatgtaacagacagaatagttatcatcaacagcctt ttggagctggagtgtgacgccaccggaacgcctgcgccagtcatcaagtggtataaagat gggaaaccagtcaggcagagcgaaggtttgcggattgcagccagcggccgacagctgctt gtttcccgcgctcagatctctgatacagctcgcttccagtgcgtagccaccaatgaggcg ggagaccataagaaggactttaatgtggtcattcaagttcctccatccatccgcacgact gggcctgccgagcgttctgtggtttttggcaagtccatcggtttggagtgcatctccagt ggcatcccaccacccagtattacctggctcaaagatggccgaccaatcgacacaactaag aagcaccttaagctgcagtcagctggcagaactctcaagatcaccgaggctagactggag gattctgggagatacacctgcctgtccactaatgcagccggtgaagctcaacagcatatt caactcagtgtccatgagcctcccagaatccccctctcaggagagattataaaccagacc attctgtcaggcttttccactgagcttgagtgcaaggcctctggcagcccattacctgca atcacttggtacaaagatggccgacccctgaccggtgcagctggtgtgtcgatgctgaaa cgtggccaggtgctggagattgagcgggcgcagctgtctgatgctggaatgtacaaatgt gtggctgtcaacctggctggagctgcagaaatattttatagcctacaagtgtttgtgccg ccgatcatctccagccgtggtggaacagtaacagtcgtggtgaatgaggttgccaggttg gaatgtgaagcctccggcgttcccattcccagtctcacatggctaaaagacggaagcccc gtggcaagcattgcacatggcatacaggtgttgtccggtggcagagtgttgatgctaaac agcgcacaggttagtgatgctggcagatacacctgtgtagtggtaaacgctggaggagaa cagcaacgagagtacaacctcaacgtttatgtgccacctaacatcaagggggaggaggtc aacgcaacagtaatgcttggacatccagtggagctccactgccagagcgacgccatccct ccaccgagacttttgtggagaaaagatggccgccagctctttaggaagcctggtctcact gtctccgcagatggaagtttacttaaggttgacagtgctcaggtgcaagatgctggcaga tatacctgtgaagccatcaatgttgctggaaaaacagagaagaactataacctcaatgtc tgggtttctcccagcatccgcgggtcacatgaggtgtcacctctgacggtaattcaagga ggtctcatcactctggtgtgtgagtctagtggcataccacctcccaacttgacatggagg aaggatggttctgaactcaagttggaccagcggctcaaggttatatcaggaggccgccag ctgcagatctctactgctgagaggtcagatacagcatcttacacctgcacagcctccagc gcatctggaacagcctccaaggagtacagcctgcaagtttatgttcgcccttccatcaga tacactgacggggactctgatgacgtcacagtgacaaaagggagtgacgtcacccttcag tgtgttgcagagggtgtgccacgaccagcgatcacatggctgaaggatggacgacccatt acaggccatcatgttgcaaagatcctgaacgaagggcgattgctgcaaattaaagatgct aaagtgtcagacacagggcgatacacctgcattgctgttaatgtggcaggccaggcagac agcaagtatgacatcagtgtgcatgtcccacccagtataattggtcaggtgcagtttcca gagaatgtgagtgttgtggtgaagaaccctgtcgctctgagctgcgaggcttcgggtgtc cctcttcctgccatctcctggctgaaggatggtcagccagttaaggcaactggttcagtg cgcatcctctcaggtggacgcagtcttcgtctaatgcatgctgcagtggaggatgctggg aggtatatttgcatcgtatctaacagtgctggagaagaaaggaagaatttcgacctcgac atccttgttccaccaagtattgtgggagagggaacggtcgtggacaccaaagtaaaggag aaacacaacatcaccctcacctgtgaaacatcaggtaaccccgtgccagagattaaatgg ctaaaggatggacagctgttgttgcctgacaggcgccaccaagtgttgtctcatggccgc ttcctccaaatctctgagagccaagttgcagacactggcaggtacagctgcctagcgtcg aacagcgcaggagaccgcagcaggcattttaacctcaatgttctggtatctcccaccatt gctgggactggcccagatatttctcctgaggaagttactgtaaccctgagcagccccacc tctctggtgtgtgaagtccagtcttaccctcctgctctgatcacctggctcaaagacggc actccgttcgaatccactcgcactgtccgagtccttccaggtgggcgaacgctgcagatt ctcaacgctaaagaggaagatgctggaaggtacacctgtgtggctacaaatgaagctggg gaaacactgaaacactatgaagtcaaggtttatgttccaccacagatcaataagaatgac attcctggagaaggactggctccgaaagaggtcaagataaagatcaacagcacactgact ctggagtgtgttgcacaggcttttcccactccagcactgcagtggtataaagacggacag attctgcagacagatgaccacgtatccattacagccaatggccgtattgttcagatcaaa catgctcaggtgtcggacacagggcgctacacctgcattgctactaatatagctggagag gatgagaaggactttgatgtaaatatacaagttcccccgaatttcaacagacctggtgga gttggtgacacaatatcagcttctggttttggaggggatgctcgggatgtgattctgaac aaccccatctctctgtactgtgagacaaatgctgtgcctcctccaacactcacctggtac aaagatggacaattactgacttcaaatgccaaagtcctgatcttaccaggtgggcgagta ttacagatccccagggcccaaattgaagactccggcaggtatacttgtgtggccatcaat gaagcaggggaagactccattcagtatgatgttagagttttattacctccaaccatacgt ggaacaaacagcgacgtgcctgatgaagtcactgtcctggtcaacaaaaccacccagcta gagtgtcatgtggatgggaatccctcacccaagatcacctggtttaaggacagccagcca atcagctctaaggattcatataggattttgtccaatgggcgaacgcttaagatgttgacc gctcagctatctaacacaggccgttatgtgtgtgtggctgagaatgtggctggaagtgca gaaaagcactttaatctcaacattcatgtgcctcctaccattatcggtgtgagctatgac aatgtgacagtggtggtgaacaactttgtgtctctttcttgcgaagctactggcttccct cctcccacactgagctggttgaatgacaggggccccattcaggccaacagtaatgctctc atcgtgccaggtggtcgtactttacagattcttaaagccaaggtgtctgatgggggaaag tacatctgtgtggccttgaatgcagcaggagaagcttacaaacacatctatctcaccgtg tttgttcctcccagtatccggggcagtaacagggactcccccgtggtgattagcgtgctt gttggtaaatctgtaactctagagtgtgaatccaatgccatccctcctcctaccatcacc tggtacaagaacggtagggtggtgacagaaacggccaacttaaatatccaggcagaagga cggatccttgagatcagcggctcagaggtgacagatacaggacagtatgtgtgcatggcc accaacgttgctggacaagtagacaagaacttccacttgaacattcatgttcttccaagt attgacggtccagcagaagagagtgttgtggaaaccatcagtaaccccatttcttttgcc tgtgatgctactggaatccccccacctagtctcacttggttaaaaaatggacaccccatt gagaactcagactctctggagatgcatatcttctcaggaggaagtaaactacagattgca aggttgcagctttctgatagtggcacatacacgtgtttggcctccaacattgaaggcaaa acacaaaagagctaccacctcaccatacaagtcccacctcgtatctctggatcagagatg cccagtgagatgggagtcctggtaaatgaaagcacccagctcatctgtcaagttcaggga acccctactcctctcatccagtggctgaaggatggggaagccatcaacaatatgggagac aatagattcagagtcagtccagatggcagcacactcgtattgaccagagctcaccctgaa gacagcggaaaatacacctgtgtggcaaccaacactgctggagaggaggacaggatattt aatctgaatgtgtatgtgcctcctgcgatacttggaaacagtgaggctgcagaggatctg atcaccgttctggacagttctgtcagtatagagtgtgttgctgctgggtctcctctgccg cagctgcactggctgagaaacggcctgcctctgccagtttcctcccacatacgacttctt tctgctggacaggtgcttcggatcacacgaatccaggtgtctgatggtggaagctacacc tgcgttgcatcaaacagggcgggagtggacaaccgacagtataaccttcaggtgcatgtt cctcctggtttggatggagcaggaagcacagaagacgtgactgtcgtcagaggaaactta gcttcgttgctgtgtatcgctgatgggaccccagcccctgacatttcatggttcaaagat gaagtggctctagcccctgaccaccacatctctttcctcaaactcaattccactttacag attatccaggcccagattaacaatacaggtcactatacctgcatggctaacaacactgct ggtcaagctagccgttacttcaatctgaaagttttagatcctccacacattgaaggctct ggagaaacatcagaagtaactgtggttgttaataatgtgctggagctccagtgtgaggct acaggtatccctccaccttctttgacctggctgaaggacggacgcccactcccacagaca gacagtctgcgtctccttcgcgggggagaggttctccgtgtggcatccgcacagctggag gacacaggcaggtacagctgcttagcaaacagtccggcaggagatgatgacaaagagttc cttgtccgagtgcatgttccaccaaacattgcaggagaaagcacacctcaggatgtgtca gtcctgcagaacagacaggtaaccctggagtgcaagtctgacgctgttccacctccaact ctgacctggctgaaagatggcaaaccacttcaggcctctgctcgtgtacgtgtcctgtct gctggacgctacctacagatcaatgtggcagagctcagcgacagagcgcagtacacctgt gtggcgagtaacatcgctggcaagacaacgcgacagtttaacctgactgtcaacgtggct ccagctatcaaggatggtcctcagatggtgtccgtgcacgttgacaagccagcagtgctt gaatgcatcgttaatggtgtgcctccaccccaggtgacctggaggaaaaatggtgtaata ctggcaggaaacaaccccaggtacacatttgtagaagatgggtctttacacgtccactca gctcaggtgaccgatactggtcggtacttgtgcatggcaacaaatcaggctgggactcaa cgcaagagagtggatctgcaagtatatgtacctccctccatcgctgacagtcggaccaat gtgactgttatcgtcaatgtgcagaccaccttatcttgtgaggccaccggcattcccaaa ccctctgtcagctggcagaaaaatggtcgaaccatcaatactgaccagaatcagaatatg tacagattgctatcatcaggctctctggtcatcatagcaccaacagtggaagacacagca gtgtacaaatgtgcggtctctaatgaagcagggaataactccaaatctgtcaacctcgct gttatcgttcctccatcgatagcggatgaatccacagagctggttgtaaccagactgtcc ccggtggtgattgcttgtactgcatctggtgtcccaaagcccacaatccactggagcaaa gatggggtgaatctgaataagaagggagagggctacagcatccttccaacaggtccagta gagatcccatcagctgagttaagtcatgctggtcgctactcctgcagagccacgaatagc gcaggctccactcaccgccacgtgcagcttactgtacaagaacttccagtaatgcagttg catccagccactctggatgtgatcatcaatagccccttcactctgccctgcagagccaca ggcacacccagacccacgattacctggcagaaggagggaatcaacctatccaccacaggt ggtggtttcacagtgcttcctaatggaagtctgcagatttccaaggcatctttgtcagac tctgggacatacatttgtgtagctcaaaaccccgcaggcactgcactgggcaagaccaaa ctcagagtgcaagttcctccagtgatccattcagagatggagggatatgtggcccctgtg gattcctctgtgacgctgcagtgccaagctgagggctcccctcctccttccgtcacatgg cacaaagacggccagctgctgagtgactccgtacgccagcgagcgctcagctctggatct ctgcagatcaccttcattcagcctagtgatgctggactatacacctgcacagctgcaaat gctgcaggctctatgagcttagatatgggcctcatcgtactgattcctccctccatccgt ggtggagagcaagaggttgtggcagtggaaaacagtcatgtccagctggtgtgtgcggca gagggcatcccacaacccacactgtcctgggaaaaagacggtattccctgcagtgaaggt gtgggggagtatacaatcctgccatctggggagctggttattgacagtgctcagcctgat gatgccggtagttatacctgtgttgccgtgaattcagtcgggcaggacagttggacggtg acgctgtctgttcatacccaccctgttttcactgagctgctcggagatgtggccctcaac aagggagagcagctcgtgctgacctgtagtgtcagcggcatacctttacccagaatcaca tgggccttcaacaacaacatcatcccagttcactatgatcaaatgaacggccacagtgaa ctgaagatagagagagtgagcaaagacgactctggtacctacacctgtttggcaggaaac agcgtcggaaccattaagtctctgggatttgtctatgttaaagagcctcccatcatcgat ggggacgttcatgccaaccgaatcgaacccttgggtggcaatgccatcctgaactgtgag gtacgaggagacccactgccaaccatccagtggagcaaaaatggaataaacattcagatc actaatcgaatccgtcagctggacaatggttctctggccatctatggcacagtgagtgaa gatgctggcagctacatgtgtgtagcaacaaatgatgctggcgtggtggagagaagtgtc accctcactctgcagagtgcacccactatcgttgtagagccggtggggacagtggtggat gcaggcaccacagttgtgcttagctgtcaggcagagggtgagcctaaacctatgatagaa tgggcccggcaagggcgccccctgctggtgaacgagcatttctccactttgtctaatggt tccctgaggatcagtagcgctcagaaagaggacactgctgaatatgagtgtgtggccaga aacttacttggatccgtgttggttagagttggccttactgtacgagtccatgggggctac tctgagtgggcagagtggggccattgcagtgtatcctgtggtgtgggaatgcagaagagg ctgagggaatgtaacaatcctttacctgcaaacgggggccgtcactgtgtaggatcagac atggaaacgcgcagttgtcatggaaagccgtgtccagtggatggtaattggtcagagtgg tcctcttgggaggaatgttcacgaacctgtggtcagggcaacaggaccagggtcaggacc tgtagtaacccaccagctcaacatggaggcataccatgtgaaggaaaggcagtggaagtc atcatgtgcagcgtcagaccgtgtccagtggcaggtaactggggatcttggttaccatgg agtccatgtagtgagacctgtggaaagggcatgcagtccagaatccgactgtgcaacagt cctccaccagcgtttgatgggccgcgttgtgagggcacagacacccagtcacaagtgtgc agagagaaaccttgtcctgtggatggaaagtggtcatcatggatgagctggggagcctgt agtgtttcctgtgggggcggtaccagacagcggacacgtctctgtgccagccctgcacct cagcacggtggcaggaagtgcgagggaaatgacgttctcatagatttctgtaacagcgac ccctgtcccatcaatggtaactggggtccatggagcaactggggcagctgcagcaagacg tgcaatggaggtcaaacgaggcgctacaggacttgtgacaaccccagacctgcttatggt gggagagcttgtgcaggtgctgatacacagatccaaaggtgcagcacagccaactgccca gttgatggtaactggggcttatggcagccatggggggaatgctccgcgtcctgtggaggc ggtgaaaagacgcgtgttcgactctgtaacaacccatctcacagtaacggtggtcgggca tgtccgggagactccactcagctgtccaggtgtaacagtcaggcgtgcccaggtggtcca ctgaaggctagaggaagcatcataggaaacatcaatgatattgagtttggtgtttccctc ctaaacgccaccatcaccaagacaaattttggcaacagactcatcaaagccaccatatct aatgtaccacggacattaggtcctgcaatgagaaagctcatctcaatcctgaaccccatc tactggaccactgcacaggaagtaggagaggctgtcaatggttacacgctgactgggggt atctttaggcgtgaaacgcaggtggagttcgctacaggtgaaatcctgaggatggcccac attgccaggggcctggactctagcggagcattgctactagatatagtagttaatggccac atcttacagctaccttcacatgctgacatcaatatcaaggactattctgaggattatatc cagacaggcccaggccagctatacgctctgtccacttgcatgttcaccatcgatgaggag agtgttccttattcctggaaccataccatcacatatgatcctgccaaaggaaagatgccc tacctggtcgaaacgctccacgccacagacatcactgctcactacaatccacttgaagaa gtcttggagtatagcatccaagctaacatcgccaagggtgatcgcagcaaccagtgtcct catggtttcactttggtagccgctgggccttactgtgcagatgagaatgaatgtgaggtt gggaacccatgttctcacacctgccacaatgcagtgggcacctattactgttcctgtccg ctaggcctcaccatctcagctgatggcagagcctgccaggacattgatgagtgttcgctt gttgggaacctgtgtcatgatggacaagactgtgagaacaccattggctcttacagatgt gtcatgcgctgtgggcggggtttcaggagaacagctgatggcctcagctgcacagatgtg aacgagtgtcaggagtcaaatccatgtaatcaactctgtttgaataccattggtagttat cgatgcgcctgtgagccgggctttcaacttaaaaacaggcggtgcattgatataaacgag tgcaggcagagggtttgccgttctgatcagcagtgtaaaaacacaagggggggttacact tgtattgacctctgccccaatggtatgaccaaaggtgggaatggaacatgtgtagatgtt gatgaatgccaagatggcacccatcaatgcagatataaccagatctgtgagaataccaag ggcagctaccactgcacctgttcacgtggatttagatcccagggagtgggacagccctgt gtcgacataaatgagtgtgaacggcttccacagccctgtgcccaccagtgcatcaacact cccggcagcttcaagtgcacctgcccaccagggcgccacctgctgggggatggcaagtcc tgtgctgggctagagcggctgccaagctatgaaagttactcatacggctaccgcacgtct cagtcttccccggagcacaggtccaatcatcagctctaccacaacctggcctctcagagc taccactcctacacgtccaccagaggcgggcgctccaggagccgtagccgcagagagact cgcaaacactcctcacagcagggtgttctcacttgtcaggaggggtttgagccaaggggt ggtcgctgcttagacatcaatgaatgtgaagtgagggacacctgccagcacgagtgcatg aacacaccgggaagctacagatgtctctgtcctgctggttaccgtctaatggctaatggc aagacctgtcaagacatagatgagtgtctggagcagaacatccagtgtggagcaaatcgg atgtgcttcaacatgagaggaagttaccagtgcattgatacaccttgtccaccaaactac catcgagatccaaccacagggttctgtctgaaagactgcccagcaaatgacctggaatgt gcactgagcccttatgcgctggagtacaagctactgtctcttccctttggcatcgcggtc aaccaggatctcatccggttagtggcctacactcaggatggtgtgatgcaccccagaacc accttcctggttgtggatgaggatgtcacattaccatttgccctgcgagatgagaacatg aaaggggttctgttcaccacacggccactacgagaaccccacacgtacaggatgaaagtc cgagccctctcctacagcgaggatggaggcattgagtaccagacaaccttcattgtctac attgcagtctccgcctacccctactga

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