Thermomonas brevis: H9L17_10450
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Entry
H9L17_10450 CDS
T06816
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
tbv
Thermomonas brevis
Pathway
tbv00230
Purine metabolism
tbv01100
Metabolic pathways
tbv01110
Biosynthesis of secondary metabolites
Module
tbv_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tbv00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
H9L17_10450 (purL)
Enzymes [BR:
tbv01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
H9L17_10450 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QNN45628
UniProt:
A0A7G9QQK3
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Position
2270903..2274802
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AA seq
1299 aa
AA seq
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MIVLEGAPALSPFRRDRLQARLQTLAPGLRIAGAWHGYWIDPETGATPDAAALRRILQAE
AGYAAAEAGAVSRFVVPRLGTLSPWASKATELLRGAGLPVKRVERGLRIDLVGWPDEAAA
QAALAKSLHDPMTQSLLEARDAGAELFAAQPAGEVEVIPLAQLEAANARLGLALADDEID
YLRMRYAELGRDPHDIELMMFAQANSEHCRHKIFNASWTIDGQPQPLSLFKMIKNTQAQT
PEHVLSAYSDNAAVVEGYAASRWRPDPATQQYHSEPATDSAFCIKVETHNHPTAIAPFPG
ASTGAGGEIRDEGATGRGGRPKAGLAGFSVSHLRIPTLPQPWEGARALNPRMASAFEIML
DGPLGAAAFNNEFGRPNLTGYFRSFELHEGDGLTRAYDKPIMLAGGLGAMDRGQVEKLRL
SPGDAVIVLGGPAMLIGLGGGAASSVASGDSAEDLDFASVQRDNPEMERRAQEVIDRCVA
RGVDNPILCIHDVGAGGLSNAIPELLHDSGVGGVIDLGQVPKDDPSLSPMQLWCNESQER
YVLGVAQSRVAEFAALCARERCPFAVVGTATAEEHLRVGYDGQAPAIDLPMDVLFGKPPK
MHRDTAHPAPPRWPQAETDALDLREAGLRVLAHPSVAAKSFLITIGDRSVGGLTARDQMV
GPWQMPVADCAITLSGFDGFTGEAMSVGERTPLALLDAAASARMAVGEAITNLIAAPVES
LNRIKLSANWMAAAGHAGEDARLFDAVKAVGMELCPELELGIPVGKDSLSMQAQWSSDGV
AQKSVSPVSLVVSAFAPVVDVRGQLTPLLRRDVESELWLLGLGGGRQRMGGSVLAQCHPE
ATSLSKASGAALPAFGGEAPDLDDPQRLRALFELIRDAREDGLLLAYHDRSDGGVFVALC
EMAFASHLGLDIRLDGWGDGRTGDPLRVLFNEELGAVVQVPTEERAAFADLVARHGLIEC
AQRIAVPTTAPMVRIADGDEELAQWRWDELFDAWWSVTHAMQKLRDNPDCADSERESARR
FDAPGLQPVLAFDAAEDVAAPFVSTGARPKVAILREQGVNSQIETAYAFDRAGFDAFDVH
MSDLIAGRFDLKDFHGFAACGGFSYGDVLGAGRGWATSILERPALRDMFAAFFARDSSFS
LGICNGCQMMAQLRDIIPGAEHWPTFQRNASEQYEARLALLEIGESPSVFLRGMAGSRIP
VAVAHGEGRAVFADVIDQGAVDVAARYVEGGRIADSYPANPNGSPDGIAGVASRDGRATL
LMPHPERTLRSANFSWAPADWPEDSPWQRMFRNARVWVG
NT seq
3900 nt
NT seq
+upstream
nt +downstream
nt
atgatcgtcctcgagggcgcgcccgccctgtcgccgttccgccgcgaccgcctgcaagcc
cgtctccagaccctcgcgcccggcctgcgcatcgccggcgcctggcacggctactggatc
gaccccgaaaccggcgcaacgccggacgccgccgcgctccgccgcatcctgcaggccgaa
gcgggctacgccgccgccgaggccggtgcggtcagccgcttcgtggtgccgcgcctaggc
acgctgtcgccttgggccagcaaggccaccgaactgctgcgcggcgccggcctgccggtg
aagcgggtcgagcgcggcctgcgcatcgacctggtgggctggccggacgaggccgccgcg
caggcggcattggcgaagtcgttgcacgacccgatgacgcagtcgctgctggaggcgcgc
gacgccggtgcggagctgttcgcggcgcagcccgcgggcgaggtcgaggtgatcccgctg
gcgcagctggaggcggccaacgcgcgcctcgggctggcgctggccgacgacgaaatcgac
tacctgcgcatgcgctatgcggagctgggccgcgacccgcacgacatcgagctgatgatg
ttcgcgcaggccaattccgagcactgccggcacaagatcttcaacgccagctggaccatc
gacggccagccgcagccgctttcgctgttcaagatgatcaagaacacgcaggcgcagacg
cccgagcacgtgctgtccgcctacagcgacaatgcggcggtagtggaaggctacgccgcc
tcgcgctggcggcccgacccggcgacccagcagtaccacagcgagccggccaccgacagt
gcgttctgcatcaaggtcgaaacccacaaccacccgaccgcgatcgcgccgttccctggc
gcctccaccggcgccggcggcgagatccgcgacgagggcgctaccggccgcggcggtcgc
ccgaaggccggccttgccggcttctcggtctcgcacctgcgtatcccgaccctgccgcag
ccgtgggagggcgcgcgcgcgctcaacccgcgcatggcctcggccttcgagatcatgctc
gacggcccgctgggcgcggcggcgttcaacaacgagttcggccggcccaacctgaccggc
tatttccgcagcttcgagctgcacgaaggcgacggcctcacccgcgcctacgacaaaccc
atcatgctggccggcggcctcggcgcgatggaccgcgggcaggtcgagaagctgcggctt
tcgccgggcgacgcggtgatcgtgctcggcggcccggcgatgctgatcggcctcggcggc
ggcgcggccagctcggtggcgtccggcgattccgccgaagacctcgatttcgcctcggtg
cagcgcgacaacccggagatggagcggcgcgcgcaggaagtcatcgaccgctgcgtggcg
cgcggcgtagacaacccgatcctgtgcatccacgacgtcggcgcgggcggcctgtccaac
gccatccccgaactgctgcacgactccggcgtcggcggcgtgatcgatctcggccaggtg
ccgaaggacgatccgtccctctcgccgatgcagctgtggtgcaacgagtcgcaggagcgc
tacgtgctgggcgtggcccagtcgcgcgtggccgagttcgccgcgctgtgcgcgcgcgaa
cgctgcccgttcgcggtggtcggcaccgccaccgccgaggaacacctgcgggtgggctac
gacggccaggcgccggccatcgacctgccgatggacgtgctgttcggcaagccgccgaag
atgcaccgcgacaccgcgcatcccgcgccgccgcgctggccgcaggcggaaaccgacgcg
ctcgacctgcgcgaggccggcctgcgcgtgctcgcccatccgtcggtcgccgccaagtcc
ttcctcatcacgatcggcgaccgcagcgtcggcggcctcaccgcacgcgaccagatggtc
ggtccgtggcagatgccggtggccgactgcgcgatcacgctctcgggtttcgacggcttc
accggcgaggcgatgagcgtcggcgaacgcaccccgctcgccctgctggacgccgccgct
tcggcgcggatggcggtgggcgaggcgatcaccaacctgatcgccgcgccggtggaatcg
ctcaaccgcatcaagctgtccgccaactggatggccgccgccggccacgccggcgaggac
gcgcgcctgttcgacgcggtgaaggcggtgggcatggagctgtgccccgaactcgaactc
ggcatcccggtcggcaaggattcgctgtcgatgcaggcgcagtggtcgagcgacggcgtg
gcgcagaagtccgtgtcgccggtgtcgctggtcgtctcggcgttcgcgccggtggtcgac
gtgcgcggccaactcaccccgctgctgcggcgcgacgtcgaatccgaactgtggctgctc
ggcctcggcggcggccgccagcgcatgggcggctcggtgctggcccagtgccaccccgaa
gccacgtctttgtcaaaggcgagcggtgcggcattgcccgcattcggcggcgaagcgccc
gacctcgacgacccgcagcgcctgcgcgcgctgttcgaactgatccgcgacgcgcgcgag
gacggcctgctgctggcctaccacgaccgctccgacggcggcgtgttcgtcgcgctgtgc
gagatggcgttcgcttcccacctcggcctcgacatccgcctcgacggctggggcgacggc
cgcaccggcgacccgctgcgggtgctgttcaacgaggagctgggcgcggtggtgcaagtg
ccgacggaggaacgcgccgcgttcgccgacctggtggcccgccacggcctgatcgaatgc
gcgcagcgcatcgcggtgccgaccaccgcgccgatggtgcgcatcgccgacggcgacgag
gaactggcgcagtggcgctgggacgagctgttcgatgcctggtggtcggtgacccacgcg
atgcagaagctgcgcgacaacccggactgcgccgacagcgaacgcgaatccgcgcgccgc
ttcgatgcgccgggcctgcagccggtgttggcgttcgacgccgccgaggacgtggccgcg
ccgttcgtttcgaccggcgcgcggccgaaggtcgcgatcctgcgcgagcaaggcgtcaac
agccagatcgaaaccgcctacgcgttcgaccgcgccggcttcgacgccttcgacgtgcac
atgagcgacctgatcgccggccgcttcgacctcaaggacttccacggcttcgccgcctgc
ggcggcttcagctacggcgacgtgctgggcgcgggccgcggctgggccacctcgatcctc
gaacgcccggcgctgcgcgacatgttcgcggcgttcttcgcccgcgacagcagcttctcg
ctgggcatctgcaacggctgccagatgatggcgcagctgcgcgacatcatccccggcgcg
gagcactggccgaccttccaacgcaacgccagcgagcagtacgaggcgaggctggcgctg
ctggagatcggcgaatcgccgtcggtgttcctgcgcggcatggccggctcgcgcatcccg
gtggcggtggcgcacggcgaaggccgcgcggtgttcgccgacgtgatcgaccagggcgcg
gtggacgtcgccgcgcgctacgtcgagggcggccgcatcgccgacagctacccggccaat
ccgaacggctcgcccgacggcatcgccggcgtcgccagccgcgacggtcgcgccaccctc
ctgatgccgcatcccgagcgcaccctgcgcagcgccaacttcagctgggcgccggccgac
tggccggaggactcgccgtggcagcggatgttccgcaacgcgcgggtgtgggtcggctga
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