Thermohahella caldifontis: AAIA72_02580
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Entry
AAIA72_02580 CDS
T11202
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tcd Thermohahella caldifontis
Pathway
tcd00290
Valine, leucine and isoleucine biosynthesis
tcd00660
C5-Branched dibasic acid metabolism
tcd01100
Metabolic pathways
tcd01110
Biosynthesis of secondary metabolites
tcd01210
2-Oxocarboxylic acid metabolism
tcd01230
Biosynthesis of amino acids
Module
tcd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tcd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AAIA72_02580 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AAIA72_02580 (leuC)
Enzymes [BR:
tcd01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AAIA72_02580 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AAIA72_02580 (leuC)
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Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
XDT72891
UniProt:
A0AB39UYA6
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All DBs
Position
538767..540197
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AA seq
476 aa
AA seq
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MAGKTLYDKLWDAHVVKQREDGTALLYIDRQLLHEVTSPQAFEGLRLAGRKPWRVDANLA
TPDHNVPTLNREQGVEGIEDPVSRIQVETLDANCDEFGITEFKMNDPRQGIVHVIGPEQG
ATLPGMTIVCGDSHTSTHGAFAALAHGIGTSEVEHVLATQCLIQRKMKNMLVRVKGRLGK
GVYAKDLILAIIGRIGTAGGTGHAIEFAGEAIEALSMEGRMTLCNMAIEAGARAGLVAVD
DKTIEYLKGKPYAPKGKMWERAVEAWRELHSDPDAVFDKVVEIDASTLEPQVTWGTSPEM
VVPVSGRVPDPEAESDPVRAESIRRALKYMGLTPNQPVTDIRLDRVFIGSCTNSRIEDLR
IAAQVVKGRKVADNIKQALVVPGSGLVKQQAEAEGLDKIFIEAGLEWREPGCSMCLAMNA
DKLGPGEHCASTSNRNFEGRQGFGGRTHLVSPAMAAAAAIAGHFVDVREGWLEEAE
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atggcaggtaaaaccctgtatgacaagctgtgggacgcacacgtcgtcaaacagcgtgag
gacggtacggcgctgctgtatatcgaccggcagctgctgcatgaagtgacttcgccccag
gcatttgaaggactccgtcttgccggacgcaagccctggcgggtggatgccaacctggcg
accccggaccacaacgtaccgaccctgaaccgggaacagggtgtggaaggcatcgaggac
ccggtttcccgaatccaggtggagacactggatgccaactgtgacgagttcggaatcacc
gaattcaagatgaatgacccacggcagggcatcgtgcatgtcatcgggccggagcagggt
gccacacttcctggcatgacaatcgtttgcggcgactcccatacctccactcatggtgca
tttgctgcactggcccacggcatcggcacatcggaggtggagcatgtgctggcgactcaa
tgcctgatccagcgcaagatgaagaacatgctggtccgggtgaaaggccggctgggcaag
ggtgtctatgccaaggacctgattctcgccatcattggccggataggtaccgccggcggt
acggggcatgccattgaatttgccggcgaggcgatcgaggcgctgagcatggaaggacgc
atgaccctgtgcaacatggccatcgaagccggtgcgcgagctggcctggtggccgtggat
gacaagaccatcgaatacctcaagggcaagccctatgcgccgaagggaaaaatgtgggaa
cgtgccgttgaggcgtggcgcgagctgcacagcgatccggacgccgttttcgacaaggtc
gtggaaatcgacgccagtacgcttgaaccacaggtcacctggggaacgtctccggaaatg
gtggtgcctgtctccggcagggtgccggaccccgaggcagaatcggatccggtcagggcg
gaaagcatccgccgcgccctgaaatacatggggctgacacccaatcagccggtgacggat
atccggcttgaccgggtgttcatcggttcctgtaccaattcccgaattgaagacctgcgc
attgcagcgcaagtggtcaagggtcgcaaggtcgctgacaacatcaaacaggcgctggtt
gtaccggggtccggtctggtcaagcagcaggcagaagccgaaggtttggacaagattttc
attgaagcaggcctggagtggcgggagcccggatgctccatgtgtctggcaatgaatgcg
gacaaactggggccgggcgaacattgcgcgtccacgtcaaaccgcaatttcgagggcaga
caggggttcggcgggcgcacacacctggtcagccccgccatggctgcggccgctgccatc
gccggtcattttgtggatgtgcgtgaaggttggctggaggaggccgaataa
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