Thermohahella caldifontis: AAIA72_10050
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Entry
AAIA72_10050 CDS
T11202
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tcd Thermohahella caldifontis
Pathway
tcd00280
Valine, leucine and isoleucine degradation
tcd00640
Propanoate metabolism
tcd00785
Lipoic acid metabolism
tcd01100
Metabolic pathways
tcd01110
Biosynthesis of secondary metabolites
tcd01210
2-Oxocarboxylic acid metabolism
Module
tcd_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tcd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
AAIA72_10050 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
AAIA72_10050 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
AAIA72_10050 (pdhA)
Enzymes [BR:
tcd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
AAIA72_10050 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
HTH_41
Motif
Other DBs
NCBI-ProteinID:
XDT71148
UniProt:
A0AB39USX5
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Position
complement(2081121..2082221)
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AA seq
366 aa
AA seq
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MLHHKTYDFFVSYYRFLNERGEAEQPLPEWAQDRSRVVAACRTMVRVRQFDQKAIALQRT
GKLGTYASVLGQEAIGTAIGQWMRPDDVLAPYYRDLPAQIQRGVTFTEALLYWGGDERGS
QYAHCREDLPNCVPIATQMCHGAGIATAFKIRGEKRAAVATCGDGATSKGDFLEALNLAG
VWQLPLVMVVNNNQWAISTPRKVQCGAATIAQKAIGAGVHGVQVDGNDYFAVGEAVRQAL
EKAHQGKGPTLIEAVSYRLCDHTTADDASRYRPAEELKAAWQREPILRLRNWLVNRGWWN
ETEEKALMAEANREIEAAVKAYLDTPPQRPESMFEFLYAQMPDMLRDQHAEVQCRAELKE
GGAHHG
NT seq
1101 nt
NT seq
+upstream
nt +downstream
nt
atgttgcatcacaagacctatgatttctttgtcagttactaccgtttcctgaacgaacgg
ggcgaggcggaacaaccgctgcccgagtgggcgcaggaccgcagccgggtggtggcagcc
tgccgtaccatggtgcgggtgcgccagttcgaccagaaggccattgcactccagcgcacc
ggcaagctgggcacctatgcctcggtgctcggacaggaagccatcggcacggccattggc
cagtggatgcggccggatgatgtgctggcgccctattaccgggatttgccggcccagatc
cagcgcggcgtcacctttaccgaggcgctgctctactggggcggtgacgagcgcggcagc
cagtatgcccactgccgggaagatctgcccaattgtgtccccattgccacccagatgtgc
cacggtgcaggcattgccacggccttcaagatccgcggggaaaagcgggcggcggttgcc
acctgcggcgacggggcgacctccaagggcgattttctcgaagcgctcaatcttgcgggc
gtgtggcagctccccctggtcatggtcgtgaacaataaccaatgggccatttccacgccc
cgcaaggtgcagtgcggtgcggccaccatcgcccagaaggccatcggtgccggtgtgcat
ggtgttcaggtggatggcaatgactactttgccgtgggggaggcggtacgccaggcgctg
gaaaaggcccaccagggcaaggggccgacactgatcgaagccgtctcctaccgtctctgt
gaccataccacggctgacgatgccagccgctaccggcctgcggaggaactcaaggcggcc
tggcagcgtgaacccatcctgcgtctgcgcaactggctggtcaaccggggctggtggaat
gagaccgaggaaaaggcgctcatggccgaagccaaccgggaaatcgaggctgccgtgaag
gcctatctggacaccccgccccagcggccggaatccatgttcgaatttctgtatgcgcaa
atgcctgacatgctgcgggaccagcatgcagaggttcagtgccgggccgaactgaaggaa
ggaggggcgcatcatggctaa
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