KEGG   Thermobacillus composti: Theco_2321
Entry
Theco_2321        CDS       T02394                                 
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
tco  Thermobacillus composti
Pathway
tco00300  Lysine biosynthesis
tco00550  Peptidoglycan biosynthesis
tco01100  Metabolic pathways
tco01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tco00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    Theco_2321
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Theco_2321
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Theco_2321
Enzymes [BR:tco01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     Theco_2321
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase POR
Other DBs
NCBI-ProteinID: AGA58432
UniProt: L0EF60
LinkDB
Position
complement(2407870..2409282)
AA seq 470 aa
MIRRTTVQLAAMCGAEMNEAAARRADAVICGVATDSRRPAEGRLFIPLSGERFDAHDYVG
DAFAGGAAASLWQAGRPVPEALAGRPLLLVDDTLAALQRLAAAYRGQLPATVIGITGSNG
KTSTKDMTASVLARRLRVHKTEGNLNNHIGLPLSILAMDENTEAAVLEMGMSGFGEIERL
TRIARPDVAVITNIGDAHLLQLGSREGIAKAKLEIAAGLKEGGVLLINGDEPLLREGAKR
AEGYGKWRLETFALGREDGWSAKLLAATAKESAFTIRPPEGPEWPGEFRVPVPGRHNVAN
ALAAAAVGALLGLDPESIRQGLGAVKLSAMRLETTHAANGAVVLNDTYNASPASVKAMIA
FVGELTGYRRKWLVLGDMLELGPDENRLHYETGAAANPDRIHAVLAVGERSKHTVRGAAE
RLGPERAIHFADKDALVRRLLAELAPDDLVLVKGSRGMRMEEVVHALVRG
NT seq 1413 nt   +upstreamnt  +downstreamnt
gtgatcagacgaacgacggtgcagctggccgccatgtgcggcgcggagatgaacgaagcc
gcggcgcggcgcgcggacgccgtgatctgcggcgtggcgacggattcccggcgccccgcg
gaggggcggctgttcattccgctcagcggcgaacggttcgacgcgcatgactatgtgggg
gacgcgttcgccggcggcgcggcagcctcgctctggcaggccggccgccctgtgccggaa
gcgctggccggccgtccgctgctgctggtggacgacacgctggccgcgctgcagcggctg
gccgccgcctaccgcggccagttgcccgcaacggtcatcggcatcacaggcagcaacggc
aaaacgtcgacgaaggacatgacggcgtccgtccttgcccggcggctgcgcgtccacaag
acggaaggcaatctgaacaatcatatcggactgccgctttcaattctcgcgatggacgag
aatacggaggcggccgtgctcgagatggggatgagcggcttcggcgagatcgagcggctc
acccgcatcgcccggcccgatgtcgccgtcatcacgaatatcggcgacgcccacctgctg
cagctcggctcgcgggagggcatcgcgaaggcgaagctcgagattgccgccggactgaaa
gaaggcggcgtcctgctcattaacggagacgagccgctcctccgggaaggcgcgaagcgg
gcggagggatacggcaagtggcgcctcgagacgttcgcgctcggccgagaggacggctgg
tcggcgaagctgctcgctgccacggcgaaggaatcggcattcacgatccggccgcccgaa
ggtcccgagtggcctggcgagttccgggtgccggtcccggggcgccacaacgtggcgaac
gcgctggctgccgccgccgtcggcgcgctgctcggcctggatccggaaagcatccggcag
ggcctcggcgcggtcaagctgtcggccatgcggctcgagacgacgcatgccgcgaacggc
gcggtcgtgctgaacgacacctacaacgccagtccggcttccgtgaaggcgatgatcgcg
ttcgtcggcgagctgacgggctaccggcgcaaatggctcgtcctcggcgacatgctggaa
ctcggaccggacgagaaccggctgcactatgagaccggcgcggccgcaaaccccgatcgg
atccacgcggtgctggccgtgggcgaacggtcgaagcacacggtccgcggcgcggcggag
cggctcgggccggagcgggcgatccatttcgcggacaaggacgccctcgtccgtcggctg
ctcgccgaacttgcgccggacgatctcgttctggtcaagggatcgcgcggcatgcggatg
gaagaagtcgtgcacgcgctcgtccggggttag

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