Thermobacillus composti: Theco_3006
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Entry
Theco_3006 CDS
T02394
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tco
Thermobacillus composti
Pathway
tco00290
Valine, leucine and isoleucine biosynthesis
tco00620
Pyruvate metabolism
tco01100
Metabolic pathways
tco01110
Biosynthesis of secondary metabolites
tco01210
2-Oxocarboxylic acid metabolism
tco01230
Biosynthesis of amino acids
Module
tco_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Theco_3006
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Theco_3006
Enzymes [BR:
tco01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Theco_3006
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGA59067
UniProt:
L0EGZ4
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All DBs
Position
complement(3144851..3146425)
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AA seq
524 aa
AA seq
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MTKSVNPSEMKRITIFDTTLRDGEQSPGAAIEPEQKIIIARQLAKLGVDAIEPGFPVSSP
GEFAAVQQISRELQGTEIVGFARAVRGDIDAAVKATQDAARRRLHLFISSSDIHLDFQLR
KTREQVLSIAREMVAYAKQFVDEIEFSPMDSTRAGIEFVIEMVEAVIAEGATIINLPDTM
GYAMPDEYEALFRTVRAQARGGDRVRYSAHCHNDLGLAVANSLAAIRGGATQIEVTVNGI
GERAGNCSLEELVMAIETRKDALKAETGIDIAEIYNTSRLVSRMMHFPVAFNKPIVGRNA
FQHESGIHQDGLLKNRATYEIMDPEAMGIPRSMIVLGKHSGRHAIKHRAAEYGIELKGEQ
LDEVYAAFKKVADAQKIVTDDQLLRIIGESTDRHEDPYTLVDLQVLSGTQRARIASVTIR
EGGTGKERTCSAMGAGPIEAVINCIKQVIPAAAEFEDLELHSLSSGEDAHGEAVVTVLHG
GRRYRGTAIHKDIILAVAQAFVGACNQAVIRTGIRDSEAEEQTG
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgaccaaatccgttaacccgagtgaaatgaagcgcatcacgatcttcgacacgacgctg
cgtgacggcgagcagtcgcccggcgccgcgatcgagccggaacagaaaatcattatcgca
cgccagctggcgaagctcggcgtcgacgcgatcgagccggggttcccggtctccagcccg
ggcgagttcgccgccgtgcagcagatttcccgcgagctgcagggcacggagatcgtcggg
ttcgcccgggccgtgcgcggcgacatcgacgccgcggtgaaggcgacgcaggacgcggcg
cgccgccggctgcacctgttcatttcgtcgtcggacatccacctcgacttccagctgcgc
aagacgcgcgagcaggtgctctcgatcgcgcgcgagatggtcgcgtacgcgaagcagttc
gtcgacgagatcgagttctcaccgatggattcgacccgggcggggatcgagttcgtcatt
gaaatggtcgaggcggtcatcgccgaaggggcgacgatcatcaacctgcccgacacgatg
ggctacgcgatgccggacgagtatgaagcgctgttccgcaccgtgcgcgcgcaggcgagg
ggcggggaccgcgtccgctacagcgcgcactgccacaacgatctggggctggcggtcgcg
aacagcctcgcggcgatccgcggcggcgcgacgcagatcgaggtgacggtgaacggcatc
ggcgaacgggcgggcaactgttcgctcgaggagctcgtcatggcgatcgagacgcgcaag
gacgcgctgaaggccgagacgggcatcgacatcgccgaaatctacaacacgtcgcggctc
gtcagtcggatgatgcatttcccggtagcgttcaacaagccgatcgtcggccgcaacgcg
ttccagcacgaatccggcatccatcaggacggcctgcttaagaaccgcgccacgtacgag
atcatggatcccgaagcgatgggcattccgcgcagcatgatcgtgctcggcaaacattcc
ggccgccatgcgatcaagcatcgcgcggcggagtacggcatcgagctcaagggcgagcag
ctcgacgaagtgtacgccgcgttcaagaaagtcgccgacgcgcagaaaatcgtaaccgac
gatcagctcctgcgcatcatcggcgagtcgacggaccgccacgaagatccgtacacgctg
gtcgacctgcaggtgctgtccggcacgcagcgcgcccgcatcgcatccgtgacgatccgc
gaaggcggcaccggcaaagagcgcacctgctccgccatgggcgccggaccgatcgaagcg
gtcatcaactgcatcaagcaggtcattccggcggcggcagagttcgaggatcttgagctc
cactcgctgtcttcgggcgaggacgcgcacggcgaagcggtcgtgacggtgcttcacggc
ggccggcgctatcgcggcacggcgatccacaaggatatcattctcgcggtggcgcaggcg
ttcgtcggcgcgtgcaaccaggccgtcatccggacgggcatccgcgacagcgaagcggag
gaacagacgggctga
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