Thermaerobacter composti: Q5761_04260
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Entry
Q5761_04260 CDS
T09555
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tcp
Thermaerobacter composti
Pathway
tcp00300
Lysine biosynthesis
tcp00550
Peptidoglycan biosynthesis
tcp01100
Metabolic pathways
tcp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tcp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Q5761_04260 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Q5761_04260 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Q5761_04260 (murF)
Enzymes [BR:
tcp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Q5761_04260 (murF)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
WPD19870
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Position
1084486..1085910
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AA seq
474 aa
AA seq
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MRLSMAEVAAATGGRLVAGDPSVAVTGGTVDSRRVRPGDLFFALPGQRVDGHRFVGQALA
AGARGAVIARPLGQVLPGGVPAGAAVVEVADTRQALADLARWVRRRRPDLRVVGITGSVG
KTTTKEMAAAVLGQRFQVLKTAGNYNTDIGLPLTLLDLEDHHQVAVLEMAMRGLGEIARL
AAIAAPEVGVVTVVGESHLELLGSLERIAQAKGELVEALPAHGVAVLNADDPRVRAMASR
TRARVLTFGQGDADVRAVAVEHRGAAGSRFRLAIRGGDGATVELAVPGPAGVTCALAAAA
VGVALGLDAATIAAGLAQARPAAMRNEIRQVGSWTLFIDCYNASPTSTRAALEALRQIAG
QRRAVAILGDMYELGEWAEEGHRQTGAVAARTVDVLLAVGRWAPQLVEGWRRAGGDRGAV
AAYADKAALVAALEGWLRPGDAILIKGSRGMAMEQVVEALLARAAAAGSSPAER
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgcgcctgagcatggcggaggtggcggccgccacgggcgggcgcctggtggcgggcgac
ccctccgtggcggtgaccggcggcaccgtggacagccgccgggtgcggcccggcgacctg
ttcttcgccttgcccggccagcgggtggacggccaccggttcgtcgggcaggccctggcg
gccggggcgcgcggcgccgtgatcgcccgccccctgggccaggtcctgcccgggggggtg
ccggcgggggccgccgtggtggaggtcgcggatacccgccaggccctggcggacctggcc
cgctgggttcggcggcggcgtccggacctgcgggtggtggggatcacgggcagcgtgggc
aagaccaccaccaaggagatggccgcggcggtcctgggccagcgcttccaggtgctcaag
acggccggcaactacaacaccgacatcggcctgcccctcaccctgctcgatctggaggac
caccaccaggtggccgtgctggagatggccatgcgtgggctcggcgagatcgcccgcctg
gcggccatcgccgcacccgaggtgggcgtggtgacggtggtgggggagtcgcaccttgag
ctcctcggcagcctggaacggatcgcccaggccaagggcgagctggtggaggccctgccc
gcccatggcgtcgcggtgctcaatgccgacgatccccgggtgcgggccatggcgtcccgc
acccgcgcccgggtgctcaccttcggccagggcgatgccgacgtccgcgccgtcgccgtc
gagcatcggggagcggcggggagtcgcttccgcctggcgatccgcggcggcgacggggcg
acggtggagctggcggtgccgggcccggccggcgtcacctgcgccctcgccgcggcggcc
gtcggcgtcgccctggggctcgatgcggccaccatcgccgcgggcctcgcccaggcacga
cccgcggcgatgcgcaacgagatccgccaggtcgggtcgtggaccctcttcatcgattgc
tacaatgcgtcacccacctcgacccgggcggcgctcgaggcgttgcggcagatcgcgggc
cagcgccgggccgtggcgatcctgggggacatgtacgagctgggggagtgggccgaagag
ggccaccggcagacgggcgcggtggcggcgcgcaccgtcgacgtgctcctggcggtggga
cggtgggcgccccagctggtggagggatggcggcgggccgggggggaccgcggcgcggtg
gcggcgtacgccgacaaggccgccctggtggccgccctggagggctggctgcgacccggc
gatgccatcctgatcaagggctcgcggggcatggcgatggaacaggtcgtcgaggccctg
ctggcgcgggcggccgcggccggttcgtccccggccgaacggtga
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