Thermaerobacter composti: Q5761_09100
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Entry
Q5761_09100 CDS
T09555
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
tcp
Thermaerobacter composti
Pathway
tcp00290
Valine, leucine and isoleucine biosynthesis
tcp00660
C5-Branched dibasic acid metabolism
tcp01100
Metabolic pathways
tcp01110
Biosynthesis of secondary metabolites
tcp01210
2-Oxocarboxylic acid metabolism
tcp01230
Biosynthesis of amino acids
Module
tcp_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tcp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
Q5761_09100 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Q5761_09100 (leuC)
Enzymes [BR:
tcp01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
Q5761_09100 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
Q5761_09100 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
WPD18516
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All DBs
Position
2226649..2227950
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AA seq
433 aa
AA seq
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MAARRPMTITEKILAAHAGLPSVEPGQLVEVRVDFLMANDITAPLAIRAFREMGATKVFD
PERVAIVLSHFAPSKDIRSADQCKVAREFAREQGLTHYYEMGEGIEHALLPDRGLVLPGE
LVLGADSHTCTYGAVGCFATGVGSTDLAYAMATGETWLKVPETLKFVYYNRLQPWVTGKD
LILYTIGRISCDGATYKAMEFTGEALADLSMDGRLAMANMAIEAGGKNGIFNPDQRTLDY
VAQRAQRPCSPVWSDPDAEYAEVYEFNAAQIEPQVALPWSPDNVRPLSQVERVPIDQVFI
GSCTNGRLDDLRMAARILRGRRVHPEVRAIVIPASRDIYLQALKEGLIEVFMAAGCVVSA
STCGPCLGGHMGVLGKGERCVSTSNRNFVGRMGHPESESYLANPAVAAASAVAGRLCHPE
ELGIRYEEVAGVA
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atggcggcacgccgcccgatgaccatcaccgagaagatcctcgccgcccacgccggcctc
ccctcggtcgaacccggccagctggtcgaggtccgggtcgacttcctcatggccaacgac
atcaccgcgcccctggcgatccgggccttccgggagatgggggcgaccaaggtcttcgac
cccgagcgggtggccatcgtcctctcccacttcgcccccagcaaggacatccgcagcgcc
gaccagtgcaaggtggcgcgggagttcgcccgggagcagggcctgacccactactacgag
atgggcgagggcatcgaacacgcgctgctgcccgaccgcgggctggttcttcccggcgag
ctggtgctgggggccgactcccacacctgcacctacggcgccgtgggctgcttcgccacc
ggcgtgggcagcaccgacctggcgtacgccatggccaccggcgagacgtggctcaaggtg
ccggagaccctgaagttcgtgtactacaaccggctgcagccgtgggtcaccgggaaggac
ctgatcctctacaccatcggccggatctcgtgcgacggggccacgtacaaggccatggag
ttcaccggcgaggccctggccgacctcagcatggacgggcggctggccatggccaacatg
gccatcgaggccggtgggaagaacggcatcttcaaccccgaccagcggaccctggactac
gtcgcccagcgggcccagcggccgtgcagccccgtctggtccgatcccgacgcggaatac
gccgaggtgtacgagttcaacgccgcccagatcgagccgcaggtggccctgccctggtcg
cccgacaacgtgcggcccctgagccaggtggagcgcgtccccatcgaccaggtgttcatc
ggctcctgcaccaacggccgcctggacgacctgcgcatggccgcccgcatcctgcgcggc
cgccgagtgcatcccgaggtgcgggccatcgtgatccccgcgtcgcgggacatctacctg
caggcgctcaaggaggggctcatcgaggtcttcatggccgccgggtgcgtggtcagcgcc
tccacctgcggcccctgcctgggcggccacatgggggtcctcggcaagggcgagcggtgc
gtcagcacctcgaaccgcaacttcgtcggacggatgggccatcccgagtcggagtcgtac
ctggccaacccggcggtggccgcagcgtcggcagtggcgggccggctctgccatccggag
gaactcggcatccggtacgaagaggtggccggggtggcgtga
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