Trypanosoma cruzi: 508971.50 Help Entry 508971.50         CDS       T01012                                  Name (RefSeq) ubiquitin-protein ligase-like   KO K10592   E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26] Organism tcr  Trypanosoma cruzi Pathway tcr04120   Ubiquitin mediated proteolysis Brite KEGG Orthology (KO) [BR:tcr00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     508971.50  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:tcr04121]     508971.50 Enzymes [BR:tcr01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.26  HECT-type E3 ubiquitin transferase      508971.50 Ubiquitin system [BR:tcr04121]  Ubiquitin ligases (E3)   HECT type E3    508971.50 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  HECT UBM Motif Other DBs NCBI-GeneID:  3541231 NCBI-ProteinID:  XP_810457 UniProt:  Q4D7V1 LinkDB All DBs AA seq 4125 aa AA seqDB search MLGRIGTARGQMGTQYQYSETMTGHYLPLPPPVLQQYTLRLKACLGDPAMTPKVFEAMLH DEEFYRDVNSMYTKEFVELLRAVGCRWLRLHVFEILGHGQDAGGNRVDTDLVEDDGAGAA AAATAGHLSLEANEEEVMEPEREGRQENTMISKEPNVYKELHSILLLLTVMGSPYRMVRD EGCLTMSCNIRLLLCRDPSLVYLGLLINFTQPHLPDKALDGVALMRVIAHGWGASPTFED VLRCSLQARQRSRQRTGACSQQDVDAAMLQLPHLVKDPLRILHERFLQRTLRGGTSQIDP VPMCRTVLKNMEEAAGDPEKLLWWCRCRLLCSQLLPSSDREEVFSGPLSDFFRSVWRTER LFSTILEEAEFDDNPGGDCEESSCGAVPSAAMLVGTIADVVHAWHFALRGCAAISGLLAI RYVQNPLDSVNCVVPQHRKFQEGSHCCLAEDWQYRLLTEYHSTHLALFTPTSSTGHASAL PAMVAQLTDILRLQPHYCPVLLMRSLALTGENTNISIAMNHGLVRAVVAVMRAYMDEQQV SDAGYEQQHIRRRTGEERTIVYGWSYEAVRILRCCFVVLERLATVSTHEYINPIVFLLTP NEEDGYELCQDICRRILHRDGHPVLLAAAFRFFSACIHHNVRDVVPALLQRGVLQTILEI GENPTILRRYNERTGGVPLSSAPVGSAGTEPRGATGPQTTSGSSSPDGRICETYAWLVSE EDATQRASVTTGRDANTIIPVDPSAYYEQAIPMLDICSVLQAFAVHNSTHAQLHRPQLMW SLLWSLIVPVSTASPAPSTGVSPLRVNTRAATAAGKDLISLLRTLPDLRDSFFEAFSETL KGLVAASQRQNPPEEIAISMWNIIACISGAEFRQLSHRIQHRRQRNYAPDHNSLIGEMLT QKLVRYKSTLSQAIRALLQLPHRISVVSANCSVLSLFVCNIPLPILDHISSVILSHVTKI AELVQTSGSAPNGGLSEDQATSLLLLTWAFFCRFHNQSPPAAISKLRCELANALFDTYVA LELARGKAVAATTTNSPTGGNEADRNDTELNRAATEGSGIFFAFSRLSTPAAMSLPTTSE TDVPADWPWVFGASHLEDSLLLQEERSLPEATATLFTVGDGGGGGAERGTLSAVDRFRES IAFMLQPSSDRRQQFFSPTRAYRQHGFLSANQQFLLPVSTAHLLTGAEKALKKIVQEMMK AVQGRLDMGNETAEGCMGGAGILRTLRVVALDALNISQLKEVEMRMRFAEGPISIVWRNG GNADGGFTALFTGILACLQFITEGVVPLRKLTPSLAAASSPYTAMGAATDNGAFTMTANC EEDENADEDGAVGSRLSSVVSSMTRILELLLRTTPERSSTRRHWVQPLLYFMLAIWRAHG LMFTPAMTLGVLARLFDFSTDILDVSADRSLSAFLSSIAEGDNEDMVQLTSFWSELLARE GGTAGDRDDDTVPESFRSPNEEGIDDAAPPASLPASGDQQQQRPCSSPHVSLAECAREWV LDVASTLRFADGVTEDEQKQMRRLCCRVCWIYTTLTPQKELPDRVAMPSGSDRHVILLPI IRRILEDPGRNYTLLELLAVLISQEETEKYFVVLFKRTQLPRAIFDCVTAEVQRLSDESS SDAFQLQRQRLRRKAMLGQLFCFLSVSSANTLGEKKMRVCAYYRSSPSNFCWMGHLCRHL HPQNRTPMRRQIKYDMSSSLVASVTSLLRGFGYSDACEEEAPSENKSSKSRPDEVSGNNT NCPKKAELEASVTSEENLNREPTGQAVAVSPASLTSAGSNSTRKAVRDAPKVELRLSDVL GITSILPDDLLLQCAELVLDYLAEEDAELEEQRQEQEQEQEPEEDGRGGNGGGGRQNKKL RELHVLETPVTHIAVDFLSKVLGSSETSLVSHLYQLNETTKKGFIVRAISRLLRNDMSGS GPRVPVMKALLDQTEHTEWVVYSAMVSAVQNEIRMGSTYTLQEKDVQELCARHAPHASAC RSHHGRGVAEVHRQAIVLSDFFVALRSVIDKHPKAFYTVFNISCVVFILHIGNRGIGQES VKTTVWLAPRKPPRQNVMGGSRTPHRLAVEKVLEMLIQRLEGRTLVPPLVTSVLNHITTL PSVASIVTSYNVNVRIPGSMQGVFAERKAAEDEQAHQQQQQQQQLTDAPVLREAPLFLTP FLAVILFMEKSQLELLEGFFFNVAQKAPSRLVHVLLHALEVMLEAIPPGKNRFSGEEEST ENASLRNPSPSDMACSFLHVLRVLLGAPRSSLVWRLCDELWQRDALEVLYRMVEKKCCNN ERDAAALLLVIRRVLLAYGKCNSTYGKKSSGSDKKNTESDGRPQLEGCSGRSGAMSSLQQ QGQPLQPPQAPQEQQPRQSLADSMAAHEASMLLLDEGDVSRTPRTQPSGAVDDAFFLEDL VRGHDQHGRNGELDGIRDGRRLQSHHEGTLTEVMFDIGEMLRPNESVLLYHSRGDSDGDS NHDNEEDTVNTAEDEENDEGDVDIVGEEVDIPGHAPTPISMRVGLQDNMSGEDDDDDDDD DDDDDDDDDDAGEDDGENEEEEEEGEEGEEDEEEEDLEELSYVIDHPPFLRATPNDMAGV VSGGLADEFGDDGLTSSQLHGLAEWEYDHYTTTLNRIPIDDDNWTLFSGQGHAAILEIIG RHRRETMEMNYSGVSGGDRHGVLSRIVSLCEAINEAVDLSWDKMLMLEPLPPVLYAADSE PPRVIPPPLPTLFASSEEASGENDAGAVGDRHETPSELPFEAGATSDPTPQEPGGSTQQV AEAAAAPNTTDTTINATVDNNSRVDVANARICALFFGNTEPGRGADPTVPPPSSSSLLSA NANAMGEARNSAPSVAGVGETMSLFGNASSTAESVSPEPPMEQQPWFGEIEPHFLVELPE SFRRELLFDHMNLLLCGQEREEGGQRTHIYAAFMNQLPPDMRMEAIEVEHRWRRVTGEDS GTGGAQGGDAPTFLTEVLATVDPEVRRDILLTCDLRYLEGNAALLAEATVLRELQSMEAQ GGEEEDDRRLREGREEGERLSGDGAAEGAMYNELFQAPAEDSHLPWFLQHQFLEEHGGRI VRPTGAEAPPINFRDNNNNNAGGGGGNRRPGRPPRGHNRVTESFLTTRIRALQNRFTREE KVPPPPNRQNGETGAHAPVPPVPIAVLRQLMELICFAKGGFPSLEYGCASSSLSVSSQLV VLLITVCVNTASATEALVNLLTVALDGPLERTVWDPTSDGRPGLDRSRIAVQVVFVIEKL IERCRAAGLSFTMLPDGVEEGGPPKPIDEPYNEAEQQAMDAGLFRRLMEVVLRFPSPRAE LSFTRILSALNAQLRALEDNTVKVRSPREQSSMPLSNTIILHPRHAHRLQWTSLCQYPCP NGSFLCDCCDTKLFHDTFAFCCSLCHYVLCPQCSLVTLTAEEESQRIRRCAYALVKSNGT LQTAARLLSHWNCTNEMGLQTVQLLRRGIKESARRDTSLVDQHSPIAVVERIIVELAKEL TEEIHTRFNAFRSAFLNKTAMGPGAVTLSGVAATTGVDPAGREWTTREASFALSYLNLRC TTSQSHAFFLPYAETLRPEQREVSLMWHASQMYLAEVASILQRLQNRSSVLLPHAVLLLL NRFCQFHMAEARRGSCSASLVMESHSTPTVEKTETERFMLDTTHTPSSVSDAAVNALARA GPRQQQQQQQTQHPQQSLRQTGRLYQQQRSNSEGESAETLDSTRDERPALPRLVRQFVER NKTTINTLIQYDPKLLEENFAFLKTEPGFIDFNIRLLDFQRHISHTTHGSRISLSISRDQ CLRDSFAQLSKLKSFHGSLNVRFRGEEGADAGGLTREWFQLLAEEMVNDDYALFIHSREG MTYRPNPFSDVNPNHLQYFKFAGTVVGMAVAHSVPIDVHFTRAVYRHMTGVQPIFRDLES VDPELYDNLNWLLRNDVNDLGLFFTVSCERFGVIQETELVPNGGHVAVTNANKSQYVRLR CEFHMTRQIEQQMEEFLKGFYTVIPRKEIRNFTAQELELVICGMPDIDVEDLRVHTLYDG YTATSPQIRWFWEVVASMTKEDRANLLQFATGASKVPHGGFSNLESASGTTQRFTITRWG DSVDLLPQAHTCFNKIDLPEYPSCEELRRKLMLAITFGSRGFSML NT seq 12378 nt NT seq  +upstreamnt  +downstreamnt atgttggggcgaattgggaccgcaagaggacagatggggacacagtaccagtatagtgag acaatgacggggcattatctgccgttgccaccgccagtccttcagcaatatacattacgt ctgaaggcgtgtctaggggatcccgcaatgacgccaaaagtttttgaagccatgctgcac gacgaggagttttaccgcgacgtaaacagcatgtacaccaaggagtttgtggagctgttg agggcagtggggtgtagatggttgcgcctgcacgtctttgaaattctgggccacggtcaa gacgccggaggcaatcgtgttgacaccgatcttgtcgaggatgacggggcgggagctgca gccgctgccaccgcaggccatcttagtttggaggcgaatgaggaggaagtgatggaaccg gagcgtgaagggaggcaagaaaacacaatgatatccaaggaacctaatgtgtacaaggaa ttgcactctatattgctgctgttgacggtgatgggatcaccataccgtatggtgcgggat gagggttgccttacaatgtcgtgtaacattcgtttgctgctctgtcgcgacccgtctctt gtctacctcggcctgctgatcaatttcacacagccgcatttgccagataaggcgctggac ggtgttgctctgatgcgtgttattgcccacggatggggggcctcacccacttttgaagat gttttgaggtgttcgttgcaggctcggcagcgaagcaggcaacgcacgggtgcgtgtagc caacaggatgtggacgccgcgatgctccagcttccacacttggtgaaagatccgctgcga atccttcacgagaggtttctgcaacggactttgcggggcggcacaagtcaaattgatccc gtgccaatgtgcaggacagtactgaaaaacatggaagaggcagcgggggatccagagaag ttactgtggtggtgccgctgtcggctgttgtgttcccagttgctaccaagctcggatcgt gaagaggtgttctcagggccattgagtgacttcttccgtagtgtctggaggacggagagg cttttttccaccattttagaggaggccgagtttgacgacaatcccggtggtgactgcgag gagtcttcatgcggggcggtgccgagtgcggcgatgcttgtcgggacaattgcagacgtt gtacacgcgtggcactttgcactacgaggatgtgcagccatttccggcctacttgctatc cgctacgtgcagaacccattggactcggtgaattgtgttgtcccgcagcaccggaaattt caggagggcagccattgctgcctcgcggaggattggcagtaccgcctcctcacagagtac cacagcacccacctcgcgctattcacaccaaccagctccaccgggcatgcgtcggcgctt ccagctatggtggcgcaactgacggatatcttgcgtcttcaaccgcactactgccctgtg cttctcatgcgaagcctggcacttacgggggagaacacaaatatttcgatagcaatgaac catggcctcgtacgcgcagtcgttgcggtgatgcgagcatacatggacgagcaacaggtg agtgatgcgggatatgagcagcaacatatccgcaggaggactggagaggagaggactatt gtgtatggctggagctatgaggcagtgagaattttgcgttgttgttttgttgttctggaa cggctcgccaccgtctcgacgcatgaatacataaatccaattgtgtttcttctgaccccc aatgaggaggatggctacgagctgtgccaagacatatgcaggcggattcttcaccgtgat ggccatcccgttcttcttgcggctgcctttcgctttttttcggcgtgcatccatcacaat gttcgcgatgtggtgcccgcgttgctgcagcggggtgtgctgcagacgattctggagatt ggcgagaatcccaccatcctcaggcggtacaacgagaggacaggtggagttccactgtca tctgcgccagtcggttcagccggtaccgagccaagaggcgctacgggcccacagacgaca tcgggatcaagcagtccggacggcaggatttgtgagacgtacgcctggctagtcagcgaa gaggacgcgacgcaacgtgccagcgttaccactggtagagacgccaacaccatcatacca gtggatccttccgcgtactatgaacaggccatcccgatgttagacatttgcagcgttttg caggcctttgccgtgcacaacagcacgcacgcacaacttcacaggccacagttaatgtgg agtcttttgtggtcgctcattgtacccgtttctaccgcatcgccggccccgtcaacgggg gtttcgccactgcgtgtcaacacccgagcagcgacggcggcagggaaggatctcatttcg ttgcttcgcacactgcctgatctgcgggacagtttttttgaggctttctctgagacgctg aagggccttgtggcggcgtcacagcgacaaaacccaccagaggagattgcaatttccatg tggaatattattgcgtgcatcagcggagcggagttccgtcaactttcgcaccgcattcaa catcgccgtcagcgcaactatgcacccgaccacaacagtttgataggtgaaatgctcact cagaagctcgttagatacaaatcaacgctttcacaggcgatccgcgcactcctgcaattg ccgcaccgtatttctgtcgtctctgccaactgcagcgtactgagtttgtttgtatgtaac atcccattgccgatacttgaccacatttcctctgtgattctcagtcatgtaacgaagatt gctgaactcgttcagacatctggatcggcgccgaacggcggtctcagcgaggaccaggca acttctttgctgttgttgacgtgggccttcttctgcaggtttcataaccaatccccaccg gcggccatctcaaaacttcggtgcgaattggccaatgcgctctttgatacatacgttgcg ttggaattggcgcgtggtaaagccgtcgccgccaccaccaccaactcccccactggtggc aacgaggccgatcgcaatgacacggaattaaaccgtgccgcaacagaagggagtgggata ttttttgctttctcacgcctcagcacacccgcggctatgtcgttgccaaccacgtctgag actgatgttcccgcagactggccatgggtgtttggggcgagccatttggaggattctctc ctattgcaggaggaacggagtttgccggaggctacagccacgttgtttactgttggtgat ggtggtggtggtggcgcagaacgggggacgctgagtgcggtcgaccgattccgtgagagc attgcgttcatgcttcagccgtcctcggatcgccgccaacagttcttctctcccactcgg gcataccgtcaacatggcttcttgtcagcaaaccagcagtttctgctgcccgtgagcacg gctcacctgctgactggggcagagaaggccctgaagaaaattgtgcaagagatgatgaag gctgttcaggggcgtcttgacatggggaacgagaccgcagagggctgtatgggtggtgcg gggatattgaggactctccgagtcgttgctcttgacgcgttgaatatttcccagcttaaa gaagtggaaatgaggatgcggtttgccgagggtccgatctctattgtctggcggaatggc ggcaacgcggacggcggctttacggcgctctttactggcattcttgcgtgcctgcagttc atcacggagggcgttgtgcctcttaggaaattaacaccatcgttagccgcagcgtcctca ccctacacggcaatgggtgccgccaccgataacggggcctttacgatgactgcaaattgt gaggaagatgaaaatgccgacgaggacggggcggtgggctcgaggctttcgagtgttgta agttccatgacgcgcattctcgagctacttttgaggacgacgccggagcggagttcgacg cgccgccactgggtgcagccactcctgtactttatgcttgccatttggcgggcccacggt ctgatgtttacaccggcaatgacgcttggggtcctcgcgcgtctgtttgacttcagtacg gacattctagatgtgagcgctgaccggtcgctttcagcattcctttcaagcattgccgag ggcgacaatgaggacatggtgcaactgacgtcattttggtcagaacttcttgcgcgggag ggagggactgccggggatagggatgacgacacggtgcccgagtctttccgttcgccgaat gaggaggggatagatgatgcagcgccgcccgcctctcttcccgcctctggggaccaacag cagcagcggccgtgttcgtcgccgcacgtctcgctggcggaatgtgcgagggagtgggta cttgacgtcgcatcgacattgcgctttgccgacggcgtgacggaggacgagcagaagcaa atgcgacgcctgtgctgtagggtgtgttggatctacactacactcacgccacagaaggag ctgcccgatagagttgcgatgccctctggctcagacaggcatgtcatcctgctgcccatc atccgccgcattctggaggatcccgggcggaactacacgctgctggagctgctggcagta ctcatctcacaggaggagacggagaaatattttgttgtgctctttaaaaggacgcaactt ccccgcgccatttttgattgtgtcacagcggaggttcaacgactctccgacgagtcttcg tcggatgcgttccaactgcagaggcagcggcttcgtcgcaaggcaatgttgggacaactc ttttgctttctttcagtctcgtcggcaaacacactgggggagaagaaaatgcgtgtgtgc gcttactaccgcagcagcccttccaatttttgttggatgggccacctctgtcgccatctg catcctcagaaccggaccccaatgcgtcgtcagatcaaatatgatatgtcttcgagtctt gtggcatctgtcacgtcacttcttaggggatttggctacagtgacgcttgtgaggaagaa gctccgtcggagaataaaagcagtaaatcgcgtcctgacgaggtcagcggcaacaacacg aactgcccaaagaaggctgaactggaggcatctgtgacgagtgaggaaaacttgaatcgg gagcctaccgggcaggctgttgccgtttcccccgcatctttgaccagtgctggtagcaac tcgacaaggaaggccgttcgagatgcaccgaaggtggagctccgactgtccgatgttttg ggcatcacatcgatattgcctgatgatctcttgttgcaatgtgccgagcttgtgttggac tacttggcagaagaagacgccgaattggaggagcaacggcaggaacaggagcaggaacag gaaccggaggaggatggtcgcggcggtaacggtggcggaggcaggcaaaataagaaactg cgcgagctgcatgttttggagaccccagtcacgcacattgcggtggattttctttcgaag gtactgggctcgtccgagacgtcccttgtgtcgcacctgtaccagctaaacgaaacaacg aagaagggatttattgtacgtgccatttcccgcctgctacgcaatgacatgtccggctcg ggcccacgtgtgccggtgatgaaggcgcttcttgatcaaacagaacacacagagtgggtg gtgtactcggccatggtgagcgccgttcaaaacgagatacggatgggcagtacatacacc ctgcaagagaaggacgtgcaggagttgtgtgcacggcacgcccctcacgcaagtgcctgc aggtcgcatcacggtcgtggtgtcgcggaggtccaccggcaggcaatcgtacttagtgac ttttttgtcgcgcttcgttccgtcattgacaagcacccaaaggcattctatacggtgttt aacatctcctgcgttgtattcatcttgcatatcggaaaccgcggcattgggcaggagagc gtcaagacgactgtgtggctagcgccccgcaaaccaccacgccagaatgtgatgggcggg tcacgtactcctcatcgtttggccgttgagaaagtcttggagatgttgatccaacgtctt gaggggcggacattggtgccgccgcttgtcaccagcgtgctgaaccatatcacaaccctt ccctctgttgcttctatcgtcacgtcatacaacgtcaatgtgcggattccggggagtatg cagggtgtctttgcagagcgcaaggcggccgaggatgagcaagcacatcaacagcaacaa caacaacaacagcttactgacgctcccgtgttgcgggaggcgcccctttttctgacgcca tttttggcggtgattttgttcatggagaagtcacagctggagctgctcgaagggttcttt tttaacgttgcacaaaaggcgccctcacgactggtgcatgtgcttctgcatgcgcttgaa gtgatgttggaagccataccaccaggcaaaaaccgtttttctggagaggaagagagcaca gaaaatgcatcattgagaaatccctctccaagtgacatggcgtgcagttttttgcacgtc ttacgggtgcttctcggagctccgcggagctctcttgtatggcggctttgcgatgagttg tggcagcgtgacgccctcgaagtgttgtaccgcatggtggagaaaaagtgctgcaacaac gaacgggacgcagcggcacttcttctagtcatacgacgtgtgctgctggcgtatggcaag tgcaacagcacctatggcaagaagagcagcgggagtgataagaaaaataccgagtcggat ggtcgtccccagttggagggctgcagtggtcgtagtggagccatgagttcgctacaacag cagggacagccgctgcaaccgccgcaagcgccgcaggagcagcaaccacggcagtcatta gccgactcgatggcggcgcatgaggctagtatgcttctactggatgaaggcgatgtctct cggaccccgcgtacgcagccctcgggtgctgtggacgacgcgttctttttagaggatctc gtcagggggcacgatcagcacggcaggaatggcgagttggacggcattagagatggcagg cggctccaatcgcatcatgaaggaactctgacggaagttatgtttgatatcggtgagatg ctacgacccaacgagtccgtgcttctgtaccacagtcgtggcgactcagatggcgacagc aaccatgataatgaggaagataccgtgaacaccgcagaggatgaggagaatgatgagggc gatgtggacattgtcggtgaagaggttgacatccctgggcacgccccaacacccatctcg atgcgggtgggcttgcaggataacatgagcggtgaagacgacgatgacgatgatgatgat gatgatgatgatgatgatgatgatgatgacgcgggcgaggacgatggtgaaaacgaggag gaggaagaagagggggaagagggcgaggaggatgaggaagaggaggacctagaagaattg tcatatgtgattgatcacccaccctttttgcgtgccacgccaaacgatatggcgggcgtg gtctcaggaggacttgccgatgagtttggggacgacggcttaacgtcatcgcagcttcat ggcctcgccgagtgggagtacgaccactacaccacgacactgaatcgaatccccattgac gacgataattggacgttgttttccggtcagggccacgcagccattctcgagatcattggc cggcaccggcgggagacgatggagatgaattacagtggggtcagcgggggcgaccgtcat ggtgttctctcgcggattgtgagcctctgcgaagcgattaacgaggcggtggatttatcg tgggacaaaatgttgatgcttgagccgctgccacctgtgctgtacgcagcggattcggag ccaccgcgtgtcattccgccaccgttgccgacgttgttcgcgtcttctgaagaagctagc ggtgagaatgacgcgggtgccgtcggcgaccgccacgaaacgccatccgagttgccgttt gaagcgggcgcaacaagcgatccgacaccccaggagccgggcggatctacccaacaggtg gcggaggctgcggctgcgcccaacaccacggacacgaccatcaacgccacagtggacaat aacagcagagtggatgttgccaacgcacgcatctgtgcgctcttctttggcaacaccgag cccggcagaggcgcggatccaacggtgccaccaccatcgtcatcatccttattatctgcc aatgccaatgccatgggagaggcgcggaattccgctccctctgttgctggtgtgggcgaa acgatgagtctttttggcaatgcatcatctacagcagagagcgtttctccggagccccca atggaacagcagccgtggttcggtgaaatcgaacctcactttcttgtggagctcccagag tcgttccgccgtgagctgctttttgatcacatgaatctgcttttgtgcggacaagagcgg gaagaggggggtcaacgcacgcacatctatgctgcatttatgaatcaattaccaccagac atgcgaatggaggccattgaagtcgagcaccgctggcgacgcgttaccggcgaagactca ggaactggtggtgcgcagggcggcgacgcgcccacttttcttacagaagttcttgcaact gttgacccggaggtgcggcgcgacattctgctaacgtgcgacttgcggtatctcgagggg aacgccgctcttcttgctgaggccaccgtactccgcgagcttcagagcatggaggctcag ggaggtgaagaggaggatgacaggcgcctgcgggagggacgggaagagggggagagactg agcggtgatggggcagccgagggagcgatgtacaatgagttattccaggcaccggcagag gactcacatttgccatggttcttgcagcaccagtttcttgaagaacatggcggccgcatc gttcggccaacaggcgcggaggctccacccattaacttcagagacaacaataacaacaac gccggtggtggtggtgggaatcggcgaccgggacgcccgccgcgaggccacaaccgcgtg acggagtcttttctcaccacccgcatccgcgcgttgcaaaatcgttttacacgcgaagaa aaagtgccaccgccaccgaatcgtcaaaatggtgaaacgggtgcccatgcccctgtcccc cccgtgccaattgctgtgcttcggcagctcatggaacttatctgcttcgcgaagggcggc tttccgtcgctggagtacggatgcgcctcctcgagtctttccgtcagttcccagctcgtg gtgctcctcataactgtgtgcgtgaacaccgcaagcgcgacggaggcattagtgaatctg ctcactgtggcactggatgggcccttggagagaaccgtttgggatccgacatcggatgga cgtcccgggctcgatcgcagccgcattgcagttcaggtggtttttgttattgagaaattg attgaacggtgccgcgcggccgggctgagtttcacgatgctccctgatggcgtggaggag ggcgggccgccaaagcccatcgacgaaccatacaatgaggcggagcaacaggcaatggac gcggggctttttcgacggcttatggaggtcgtcctgcgctttccgtcgccgcgcgcggag ttgtcttttacgcgtattttatctgcccttaacgcgcagttgcgggcactggaggataac accgtgaaggtgcggtccccgcgcgagcagtcctctatgccgctctccaacactatcatt ctgcacccacgccacgcccatcggctgcagtggacaagtctttgccagtatccatgcccg aacggcagctttctttgcgattgctgtgacacaaaactgttccatgacacgtttgcgttc tgctgttcactctgccactatgttctttgtccacagtgcagtcttgtaacgttgactgcg gaggaggagtcacaacgcatacgtcgttgcgcttacgcccttgtgaaatcaaacgggacc ctgcagacggccgcacggctcctttcccattggaactgtacaaacgagatggggctgcag acggtgcagcttctccggcgaggcatcaaggaaagtgcacggcgtgacacaagtttggtg gatcaacacagtccaattgcggtggttgagcgcattattgtcgaacttgcaaaggaactc acggaggagattcatacacgtttcaatgcgtttcgcagtgctttccttaacaagacggcg atgggacccggcgccgtgacgttgtccggtgttgccgccaccacaggtgtcgacccggct ggaagggagtggaccacgcgagaggcgagctttgcgctttcttacctgaacctgcggtgc acaacgagtcagtcacacgcatttttcttgccgtacgccgagacacttcgacccgagcag cgtgaggtgtcgctgatgtggcacgcctcgcagatgtatcttgccgaggtggcatccatt ttgcagcggctacaaaatcgctcttctgtgcttttgccgcacgcggtacttctcctgttg aatcgattctgtcaattccacatggcggaggcgcgacgagggtcgtgctcggcaagtctt gtcatggagagtcacagtacccccacggtggagaagacggagacggagcggttcatgctg gacaccacacacacaccctcaagtgtctcagacgccgctgtgaacgccctcgcgcgtgcc gggccgaggcaacagcaacagcaacaacaaacacaacatccacagcaatcattgcggcaa actggacggttgtatcaacagcaacgatccaattcagagggtgaaagtgctgaaacattg gactcgacgcgtgacgaacgtcccgcgctgccgcgtttggtgcgtcagtttgtggagcgc aataagacgactatcaacaccctcattcagtatgacccgaagctgctagaggagaacttt gcctttcttaagacagagcccggatttattgactttaatattcgtctgcttgacttccag cggcacatcagccatacgacgcatgggtctcgaattagtctgagcatcagccgtgatcag tgtttgcgtgatagtttcgcccaactctcaaagctaaagtcctttcacggatcgttaaat gtgcgcttccgcggtgaggagggtgcggacgcgggcggtttgacacgggagtggtttcaa cttcttgcggaggagatggtaaacgacgattatgcgctctttattcactctcgggagggc atgacgtaccggccgaaccccttttcggatgtcaacccgaaccacctgcagtatttcaag tttgcgggcaccgttgtgggcatggcggtagcgcacagcgtccccatcgacgtgcacttt acgcgtgcggtgtaccgccacatgacaggcgttcaacccatcttccgcgaccttgagagc gtcgacccggagttgtatgacaatctcaactggcttttgcggaacgacgtcaacgacttg ggtctctttttcactgttagctgcgagcggtttggcgttattcaagagacggagcttgtg ccaaatggtgggcacgttgccgtgacgaatgcgaacaagtctcagtacgtacggctgcgt tgcgagtttcacatgacgcggcaaattgaacaacagatggaagaatttcttaagggcttc tacaccgtcatcccgcggaaggagatacgcaatttcactgcgcaggagctggagcttgtc atctgcggcatgccggacattgacgtggaggacttgcgtgtgcacacgctgtacgatggc tacaccgccacctctcctcagattcggtggttctgggaggtcgtcgcatccatgacgaag gaggaccgcgcgaatcttttgcagtttgccactggcgcgtcgaaggtgccacatggtggg ttcagcaacttggagtcggcgagcgggacgacacagcggttcaccatcacgcgttggggc gacagcgttgatcttctcccacaggcgcacacctgcttcaacaaaattgacctgcccgag tacccgagctgcgaggagctgcgaaggaaattgatgctcgccatcactttcggcagcagg ggattttcaatgctgtag

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