Thermomonospora curvata: Tcur_2410
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Entry
Tcur_2410 CDS
T01127
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
tcu
Thermomonospora curvata
Pathway
tcu00860
Porphyrin metabolism
tcu01100
Metabolic pathways
tcu01110
Biosynthesis of secondary metabolites
tcu01120
Microbial metabolism in diverse environments
tcu01240
Biosynthesis of cofactors
Module
tcu_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
tcu_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
tcu00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Tcur_2410
Enzymes [BR:
tcu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Tcur_2410
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Gene cluster
GFIT
Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
ACY97973
UniProt:
D1A3S0
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All DBs
Position
complement(2804090..2805262)
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AA seq
390 aa
AA seq
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MNTDHEPLAGFAVGVTAARRHEELAALLERRGARVVHAPAIRLVPLADDAELLHATNVCI
ADRLDYVVVTTAIGFRAWLETADGWGLRDALIERLHKARILARGPKARGAIRSAGLQEEW
SPDSESCQELLRHLLAEDLTGTRIAVQLYGEPLPDFTGALRAAGAEVIEVPVYRWSRTDD
STPLRRLVGQAVAGTIDAITFTSAPAVTATLAVAAEDGLEEALLEALRTHTVAACVGPVT
AQPLTDRGVPTVQPERARIGALVRALAADLPRRRARRINVRGHTLELRGHAVVLDGQLRP
IAPAPMAILRALARRPGHVVSRAELCTVLPSRVITGSGWGRDGRPQADEHAVEMAVARLR
RGLGRSGIVETVVKRGYRLACDPVRTDRPF
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaacactgaccatgaaccgctcgccgggttcgcggtcggggtgaccgcggcacggcgg
cacgaggagttggccgcgctgctggaacggcgcggggcacgggtggtgcacgcccccgcg
atccggctggtgccgctggccgacgacgccgaactgctgcacgccaccaacgtgtgcatc
gccgacaggctcgactatgtcgtcgtcaccaccgccatcggtttccgcgcctggctggag
acggccgacggctgggggctgcgcgacgccttgatcgagcggctgcacaaggcccgcatc
ctggcccgcggccccaaggcccgcggcgccatccgctcggcgggcctgcaggaggagtgg
tcgccggattcggaaagctgccaggagctgctgcgtcacctgctggccgaggacctgacc
ggcacccgcatcgcggtgcagctgtatggggagccgctgccggacttcaccggcgcgctg
cgcgccgccggcgccgaggtgatcgaggtgccggtctaccgctggtcgcgcaccgacgac
tccacgccgctgcgccggctggtggggcaggccgtggccggcaccatcgacgccatcacc
ttcaccagcgcccccgccgtcaccgccacgctggcggtggcggccgaggacggcctggag
gaggcgttgctggaggcgctgcgcacccacacggtggccgcctgcgtcggcccggtcacc
gcccagccgctgaccgaccgcggcgtacccaccgtccagcccgagcgggccaggatcggg
gcgctggtgcgggcgctggccgccgacctgccgcggcggcgggcccggcggatcaacgtc
cgcggccacaccctggagctgcgcgggcacgccgtcgtgctggacgggcagctgcggccg
atcgccccggcgccgatggcgatcctgcgggcgctggcccgccggcccggccatgtggtc
tcccgggccgagctgtgcacggtgctgcccagccgggtgatcaccggaagcggctggggc
cgggacggccgcccgcaggccgatgagcacgcggtggagatggcggtggcccggctgcgg
cgcggcctgggccgctcgggcatcgtggagaccgtggtcaaacgcggctaccggctggcc
tgcgacccggtacgcaccgatcgtcccttttga
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