Hydrogenovibrio crunogenus: Tcr_0564
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Entry
Tcr_0564 CDS
T00296
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tcx
Hydrogenovibrio crunogenus
Pathway
tcx00300
Lysine biosynthesis
tcx00550
Peptidoglycan biosynthesis
tcx01100
Metabolic pathways
tcx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tcx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tcr_0564
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tcr_0564
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tcr_0564
Enzymes [BR:
tcx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tcr_0564
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SRP54
RepB
Motif
Other DBs
NCBI-ProteinID:
ABB41160
UniProt:
Q31I63
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All DBs
Position
635049..636473
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AA seq
474 aa
AA seq
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MTWNLADLVEAVNGVLAGELLGDEPVVFTSVSTDTRTLKSGALYIAIKGEHFDGHAFIGE
AVRQGAVAVLISEPMETVVPAVLVDDTRIAFGQFAAWHRQQMSLKGLVGVTGSNGKTTTK
ALLAHILSKQAQVLSTQGNLNNDYGLPRTLLELSTSDDYAVIEMGANHVKEIAYLTQIAK
PDVAVITLAAGAHLEGFGSLEGVIETKGEILDGVCEGGKAVLNTDSPGFEYWIEKSQQLG
LSVITFGQARFANVQVTDFTQAENQITFTLDLNWQNIRQAEVVTMPVLGFHNAMNAAAAT
AACLALGLSWSEIYPGLGDFDGVAGRLQQSKLPQGLLIDDSYNANPSSVKAAIDALVQLP
GPSAVCLGGMAELGAESEALHQDVAAFAKAKGVTHLLLFGEATQCMPTVFGEGAKWFESH
EALAQEAVDLIQQDKIQNVLVKGSRSAKMEQVSQKVLARLEANSSSSNHHNNRG
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgacatggaatttagccgatcttgttgaggccgtaaacggagtattggcgggtgagtta
ttgggcgatgagccggtggtttttacatcggtcagtacggatacgcgcacgttaaaatcc
ggtgcattgtatatcgcaattaaaggcgagcactttgatggtcatgcctttatcggagaa
gcggttcggcagggtgccgttgcggttttaatatccgaaccgatggaaacggttgtgcct
gcggttttagtggacgatacccgcattgcttttggtcaatttgccgcttggcatcgtcaa
caaatgtcgttaaaaggattggttggggtgacgggttctaatggcaaaacgactacaaaa
gcactacttgcacacatattatccaagcaggctcaggttctctcaacgcaagggaactta
aacaatgattatggcttgcctcgcaccttactggagctgtcaacatcggatgattatgcg
gtaattgaaatgggcgctaatcatgtcaaagagattgcgtacctcacccaaattgccaag
ccggatgttgcggtcattacattggcagcgggcgcgcatctggaagggtttggttctctg
gaaggcgtgattgaaactaaaggtgaaattctggacggtgtttgtgaaggcggcaaagcc
gttttaaacaccgattcccctgggtttgaatattggatcgaaaaaagtcaacagctaggg
ctgtcagtaatcacgtttggacaggctcgttttgccaatgtacaagtaaccgattttaca
caggctgaaaaccaaattacatttacacttgatttgaattggcagaacatacgccaagcg
gaagtggtgacgatgcctgtgcttggatttcataatgcaatgaatgccgccgctgcgacg
gctgcgtgtttagcgttagggttgtcatggtcggagatttacccaggcctgggcgatttt
gatggtgttgcaggacgattacaacaatcgaaattaccccaagggcttttgattgatgac
agctataacgcgaatccttcttctgtcaaagcggcgattgatgcgctggtccagttaccg
ggaccatcagccgtttgtttaggaggcatggcggaacttggcgcagaatcagaggcattg
catcaggacgttgccgcttttgcgaaagcgaaaggggtgacgcacttattgctgttcggt
gaggcaacacaatgcatgccaaccgtctttggagaaggggctaagtggtttgagtctcac
gaggccttggctcaggaagccgtcgatttaatccaacaggataaaatacaaaacgtatta
gtgaaaggctcccgttcggccaaaatggaacaggtcagccaaaaagtgttagccagattg
gaagcgaactcttcttccagcaatcaccacaataaccgaggataa
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