Thiomicrospira cyclica: Thicy_1346
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Entry
Thicy_1346 CDS
T01517
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tcy
Thiomicrospira cyclica
Pathway
tcy00300
Lysine biosynthesis
tcy00550
Peptidoglycan biosynthesis
tcy01100
Metabolic pathways
tcy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tcy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Thicy_1346
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Thicy_1346
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Thicy_1346
Enzymes [BR:
tcy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Thicy_1346
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NNH6
Motif
Other DBs
NCBI-ProteinID:
AEG32110
UniProt:
F6D9R1
LinkDB
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Position
complement(1528923..1530380)
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AA seq
485 aa
AA seq
DB search
MTMGKERMHHSFGRWTLGQLANWLNVILPAEWQAQADLAISQMVTDSRAVKPGDVYIAIE
GTRFDGHRFIAQAIEQGAVACIVSNKQYAKQSVPCLIVADTTRALGRLGQAHRQAAKLEC
LVAVTGSNGKTTVKELLAALFATQGPTLATRGNFNNQFGVPRTLLELTDEHRYAVIEMGA
NHQGEIDCLTRLAEPDIAIITLAAPAHLEGFGSLDGIITAKGEIMHGLKPNGVGIINTDS
PGFDQWQAKLARSDRKMICFGQAASADIRIRQVTTEKNGIRFELYYQQAWHQVVSPLLGA
HNAYNLAVGAAVAQVMGWSWDVVAPVFESFTGTDGRLQTFQVGAMTLIDDSYNANPSSMA
AGLDSLHALASTDQRPMIACLGTMAELGTTAPEAHYQIGRQAVQLGVQQLWAQGPNAQDY
VAGFKSLSRSKTLAEVADHATMIDQLVTLYHTGEPWVVLIKGSRSAAMDQLRSGLTERVT
HAHLP
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgaccatgggtaaagagcgcatgcaccattcatttgggcgatggacactaggtcaatta
gcgaattggctgaatgtgatactacctgccgaatggcaagcgcaagcggatttagcgatc
tcacagatggtcacagattcgcgtgccgtaaaaccgggtgatgtttacatcgcgatcgaa
ggaactcgttttgacggacaccgttttatagcacaagcgattgagcagggcgcggttgct
tgtattgttagcaataagcagtatgccaagcaaagcgtaccttgtttgattgtggctgat
actacacgagccttgggacgtttaggtcaagcacaccgtcaagccgcgaagctggaatgt
ttagtagcggtgacgggatcaaatggtaagaccaccgtgaaagagcttttggccgcgctg
tttgccacccaagggccaaccttggcaacacgcggtaattttaataatcagtttggggtg
ccaagaacgctacttgagttaacggatgaacaccgctatgcggttattgaaatgggcgct
aatcatcaaggagaaatcgattgccttacgcgcttggctgaacccgatatcgctattatt
acgcttgcggcaccggcacaccttgagggctttggtagtttagatggcatcattaccgcc
aaaggtgagatcatgcatggtttaaagccaaatggtgtcggcattattaataccgactcg
ccaggttttgatcaatggcaagcaaaactagctcgaagcgatcgcaagatgatctgtttt
ggtcaagcggctagtgcggatattcgtattcgccaggtcacgactgaaaaaaacggcatt
cgatttgagctctattatcagcaggcctggcatcaggttgtaagcccgttattgggggca
cacaatgcctataacttggcggtcggtgccgcggtggctcaggtaatgggttggtcctgg
gatgtggtggcacccgtatttgaaagtttcaccggaaccgatgggcgtttacaaaccttc
caagtcggtgcaatgaccttaattgatgatagctacaatgcaaaccctagttcaatggct
gctgggctggatagtttgcatgcgctcgcgagtacagatcagcgtccgatgatagcttgt
ttaggtactatggctgaattaggtacaacggcgccagaggcgcattatcagattggtcgc
caagctgtccagcttggggtgcagcagctgtgggcgcaaggcccaaatgcgcaggattat
gtggcgggatttaaatcattatcgcgaagcaaaacgctggctgaggttgccgaccatgca
acgatgattgatcagcttgttacgctctatcacactggcgaaccttgggtcgtcttaatc
aaagggtctcggagtgcggcaatggatcaattgcgctctggtttaacagagagggttacc
catgctcatttaccttag
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