Triplophysa dalaica: 130437255 Help Entry 130437255         CDS       T09616                                  Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism tdw  Triplophysa dalaica Pathway tdw04020   Calcium signaling pathway tdw04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:tdw00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     130437255    04020 Calcium signaling pathway     130437255  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:tdw04040]     130437255 Ion channels [BR:tdw04040]  Voltage-gated cation channels   Ryanodine receptor    130437255 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 Syntaxin-18_N EF-hand_8 Motif Other DBs NCBI-GeneID:  130437255 NCBI-ProteinID:  XP_056624492 LinkDB All DBs Position 15:21677091..21772623 Genome browser AA seq 4888 aa AA seqDB search MAEGGDAEDEIQFLRTDDEVVLQCVACIQKENRKFCLSAEGLGNRLCYLEPTSEAKYYPP DVCICSFVLEQSLSVRALQEMLAKTGQNNDQFIRKAAHSAGHRTLLYGHAILLRHSFSGM YLTCLKTSRSMTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSS ERYLHLSISNGNIHVDASFMQTLWNVHPICSGSSVEEGYLLGGHVLRLFHGHDEVLTIPA SDQSEEEQRIVNYETGKAGAKARSLWRLEPLRISWCGSHIRWGQPFRLRHLTTGHYLALT EDRGVVLQDRERSDTSSTAFCFRASKEKLDCSVKRDVEGMGVAEIKYGDSLCFVMHAATG LWLSYQAPDVKSTRLGPLKRRVCLHSEGHMDDGLTLQRCQHEESRAARIIRNTTRLFSTF IRELESLSSKNHVFVVLPIEEVLQTLNDLIAYFRLPDAELEHEKKQIQLRSLKNRQNLFK QEGMLSLVSNCIDRLSVYNSAAHFGEHAGEDAAAAWKDILNLLYELLASLIRGNRNNCTQ FSQNLDWLVSKLERLESSSGILEVLHCILIESPEALNIIQRGHIKTIISLLYKHGRNHKI LDVLCSLCVCNSVAVRANQNLICDHLLSRRDLLLQTRLVNDVQSMRPNIFVGVSEGSAQY RRWYFELVIDHVHHFMTGEPSHLRVGWASTRGYAPYPGGGEGWGGNGVGDDLYSYGFDGL HLWSGRISRTVASVKQHVLTSDDVVSCCMDLNAPSISFRINGQPVQGMFETFNSDGLFFP VVSFSAGVKVRFLLGGRHGEFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDVGGVRDL LGNTHFTSQASFIPKPVDTSQTVMPPHLEKVRDRLAENIHELWGTNKIEMGWSYGKIRED NKRQHPCLVDFSKLPETERSYNIQMSTETLKTLLALGCHVVQVRVNAEEDLKKLKLPKNY MMSNGYKPAPLDLSDVKLTPGQELLVDKLTENAHNVWAKDRVKQGWTYGIQQDVKSKRNP RLLPYALLDERTKKSNRDSLREAIRTLIGYGYSVEPPDQDAGHVVERLSIDKIRFFRVER TYAVKTGKWYFEFEVVTGGDVRVGWARPGCKPDVELGTDDQAYVFDGHRGHRLHMGGRLF GRCWHAGDVVGCMINMEDKSMIFTLNGEILITNKGSELCFADFDLDDGFIPVCSLGLSQV GRMNLGKDASTFKYYTMCGLQEGFRPFAVNMNREVTMWFSKRLPTFFNVPRDHSDITVTR IDGTVDSPPCLKVTHKTFGTQNSNSDMVFFRLSMPVDFQSTFRSSTSHMNGVYEEEPLKL RHRYPVKSMKHSEESRRIDYSSITTYYHSVRIFAGQDPSCVWVGWVTPDYHYYSNDFSLS KNRTVTVTLGDERGRVHESVKRNNCYMVWCGDVGSAGQTGGRSNADLEMGCLIDVATGLL TFSVNGKELPTSHLVEPSTKLFPAVFVRPTSSSLFQFELGKIKNTMPLSSAIFKSEHKNP VPQCPPRLDVQTISSVLWSRMPNIFLKVETSRISERHGWMVQCNEPLQMLAVHIPEENRC VDIMELSEQKELRKFHHHTLKLYCALCAHGNTRVAHALCSHLDQSQLLYTIDNQYLSGML REGFYGVLISVHLETARAARLMMNNEFIIPVTPETRSIQLFPDASKRHRPPGVGLSTSLK PKLNFAPPCFISAKRNQHLYSPEIPLDVLKEKAISMLTEAVQGGGDHIRDPVGGSVEYQF VPILRLISTLLTMGILTSRDVHKILLLIEPNVFGERKEEGSRETGVKEGVTGAEEKTVET GEEEPVKGRKVMKGLLEKKLPECVKRQMCDLLHYFCDCELRHRIESIVSFSDGFVSKLQF NQKFRYNELMLALNMSAAVTAKKTKEFRSPPQEQINMLLNFDMGEGCPCPEDIQEELYDF HTELRLHCGIPVEEPEEHEDTSLKGRLLALVYKIKGQPQKSDTQPREKEQTAPTNLKELI SQTMVSWAQETHIQDPELVRVMFSLLRRQYDSIGELLRAMRKTYTISAASVSDTIHLLAS LGQIRSLLSVRMGKEEEQLMIDGLSDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGG KSQEIAFPKMVASCCRFLCYFCRISRENQKAMFDHLSYLLENSSVGLASPSMRGSTPLDV AASSVMDNNSLALALEEPDLDKVVTYLAGCGLQSCSMLVAKGYPDISWNPIEGERYLSFL RFAVFVNGESVEENSSVVVKLLIRRPECFGPALRGEGGNGLLAAMNEAIKISENPALDLP TTAPGHTSDTSTEGEEEEEVVHMGNAIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRA ILRSLVPIEDLVGIISIPLKMPVLNKDESVTEPDVSASFCPDHKAPMVLFLDRVYGIEDQ SFLLHLLEVGFLPDLRAAALLDTESVRTTESALAMNRYIGSAMLPLLTRCAPHFTGTEHH TALIDSTLYTIYRLSTCCSLTKAQRDAIEECLLAVCRYLRPSMLQPLLRRLVFDVPLLSE YCMMPLKLLSNHYEQNWKYYCLPSSWGGHGLPSEEELLLTKKIFWGIFDSLSQKTYDQEL FKMAMPCLSAIAGALPPDYIDPSLSTALEKHESVDTQGNFDPRPINTANVCLPEKLEYTA NKYTEHCHEKWAAEKVMLGWKYGENVDEKLKTHPMMRSYKALTEKEKETYRWSVRESLKS MLAMGWTIDRTKEGEMTFQLREIEKMRRTSQVSQGNGYSPTPLDMSNVPLSRELQSMVEV LAENYHNIWAKKKKSDLVAKGGTHPLLVPYDTLTAKEKVKDRERAQDLFRFLLINGHSVS RGLKDIEQDSSSMEKRFAYKFLKKLLKYVDSAQEFIAHLEVMASSGQNNRSPHEQEIKFF AKVLLPLIDQYFKNHSLYFLSSATKTLSSSGYASNKEKEMVTSLFCKLAALVRHRISLFG SDSTTMVSCLHILAHTLDTRTVMKSGSELVKAGLRTFFENAAEDLEKTLENLKLGKFTHS RSQMKGVSQNINYTTVALLPILTALFEHITEHQFGSDLLLDDVQVSCYRILSSLYSLGTG KNIYVERQLPALGECLATLAGVIPVAFLEPPLNKHNIYSVFNTKTSRERAVAGMPECVED MCPELPRLDGLMKDINDMSESGARYAEMPHVIEVVLPMLCNYLSYWWEKGPENCSENRVS VCSTTVTSEHLSIILGNILKILNSNLGIDEASWMKRIAVYAQPIISKARADLLKAHFLPT LEKLKKKTVKVVAEEELLKADGKGDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRS RWLKEPDGDSHELFKMVAEIFILWCKSHNFKREEQNFVVQNEINNLSFLTGDSKTKMSKS YLQKSGGQDQERKHKKRRGDFYSIQTSLIVAALKKMLPIGLNMCTPGDQELIMLAKTRHS LKDTDEEVKEHIRQNLHLQEKSDDPAVRWQLNLYKDVIVKNEGPPDPEKTVERIHRISAA VFHLEQVEQPLRSKKFVWQKLLSKQRKRAVVACFRMAPLYNLPRHTINNYFLKSYQCFWL DRFLESSDRDSLLTIITKTQPKTDEEEDEIRETQPDPLHQLILHFSHNALTERSSVEDDQ LYVAYADMMAKSCAENEEDDDEEKEKSFEEKEMEKQKTLYQQARLHDRGAAEMVLQMISS SKGRLGRMVTFTLKLGISILNGGNVLVQQKMLDYLKEKRDVGFFKSLSGLMQSCSVLDLN AFERQNKAEGLGMVTEEGCINMRERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRT QTGNTTTVNIIISTVDYLLRLQESISDFYWYYSGKDVMDKAGQRNFSKALAVAKQIFNSL TEYIQGPCIGNQQSLAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELLDLQKDMIV MMLSLLEGNVVNGTIGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDSFKEHDPDRK GVISKKEFQKSMESQKQYSQSEIDFLLSCAEADENDMFNYEEFVERFHEPAKDIGFNMAV LLTNLSEHMPHDARLATFLNLAESVLNYFEPFLGRIEIIGGAKRIERVYFEISESSRTQW EKPQVKESKRQFIFDVVNEGGESEKMELFVNFCEDTIFEMQLASLISEPDAAERPEEDDN DDALSVTENQEEEEDNAALESSSAFTLACVSTRKSLSNLRRMLSLKSIRRQYRKLRKMSV KEMIRGFFCFFWTIFVGTFRFLYNLLWGFFHILWSTLFGGGLVEGAKNMKVTDILGNMPD PTQFGIHGDVLEMEKLEYCDASEASELGCQSVGERAEMDLMSELMNVQPRREGGKHGMEP GLGDVSEVVGVDAPSLASAVHQKKAQEAAMNAAESEAKWESEKADVEDKEKTYQGRRDEP VSGPAAYKERKPVKNRGGLKKETPDACMASFLAGLDVYQTKMLNYLARNFYNLRFLALFV AFAINFILLFYKVTGEDSDDLDPWVRRGGAGAGDDDGVVEYFVLQESSGYMAPTLRFLAV MHTLISSLCVLGYYYLKVPLVVFKREKEIARKLEFDGLYITEQPSDDDIKGQWDRLVINT PSFPNNYWDKFVKRKVINKYGDLYGAERIAELLGLDKSALDFNPTEDAVMKDASLLSWLS SIDTKYHVWKLGVVFTDNSFLYLVWYTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSS VTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSSDEDEPDMKCDDMMTCYLFHMYV GVRAGGGIGDEIEDPAGDPYELYRILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQ VKEDMETKCFICGIGNEYFDTTPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESY VWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14667 nt NT seq  +upstreamnt  +downstreamnt atggctgaaggtggagacgcggaggatgagatccagttcctgcggaccgatgacgaggtg gtcctgcagtgtgtggcgtgtattcagaaagaaaaccggaagttctgtctgagcgctgag ggtttgggaaaccgtctctgttatctggagcccacatcagaggccaagtattatcctcca gatgtgtgtatctgtagtttcgtgctggagcagtctctgtccgtgcgtgcgctgcaggag atgcttgccaaaactggacaaaacaatgaccaattcattagaaaggcggctcacagcgca ggacacagaacgttactgtacggtcacgcaatcctcctcagacactccttcagtggaatg tatctgacctgtttgaagacatccagatcaatgacagataaattatcctttgacgtcgga ctgcaagaggattcaacaggtgaagcctgctggtggaccattcacccggcgtccaaacag agatctgaaggagagaaagttcgtatcggtgatgatctcattctcgtcagtgtttcatcc gaacgctatcttcatctgtctatatccaacggcaacattcacgtggatgcgtctttcatg cagacgttgtggaatgtgcatcccatctgttcaggaagcagcgtggaggaaggatatctt cttggcggtcacgtgttacgtctgtttcacggtcatgatgaggttctgaccatcccggcc tctgatcagagtgaagaagaacagaggatagtgaactatgagacggggaaagcaggagct aaagcgagatctctgtggaggctggagccgttacgcatcagctggtgtggcagtcacatc cgctggggtcaacccttccgtctccgtcacctgaccaccggtcactatctggccctgacg gaggacagaggggtcgttctgcaggaccgcgagagatcagacacctcgtctacagcgttc tgcttcagagcgtctaaggagaagctggactgcagcgtgaagcgtgatgttgaggggatg ggcgtggcagagatcaaatacggagattctctgtgttttgtgatgcacgcggcgacgggc ctgtggctgtcctatcaggcgcctgatgtcaaatcaacacgtctgggtcctctgaaacga cgcgtgtgtcttcactcagagggacatatggatgatggtctgactttacagcgatgtcaa catgaggaatccagagccgcgcgaatcatccgcaacacaacacgactcttcagtaccttc atcagagagctggagagtttgagcagtaagaaccatgtgtttgtggttctgcccattgaa gaagttcttcagacgctcaatgatctgatcgcgtacttcagactgcccgatgctgaactg gaacatgagaaaaaacagattcaactgcgttccctgaagaaccgacagaacctcttcaaa caggagggaatgctgtctctggtgtctaactgcatcgatcgcttaagtgtttataacagc gccgctcattttggtgaacacgctggtgaagatgcagctgcagcgtggaaagacattctc aacctgctctatgagctgctggcttctctcatccggggaaacagaaataactgcacgcag ttttcacagaatctggactggttggtcagtaaactggagaggttagaatcatcttcaggg atcttggaggttcttcactgtattctgatcgagagtcctgaagctctgaacatcatccag agaggacacatcaagaccatcatctctcttctctacaaacacggacgaaaccacaagatt ctggacgttctctgctctctgtgtgtgtgtaacagtgtcgctgtgagagccaatcagaat ctcatctgtgatcacctgctgtccaggcgagacctcctcctgcagacacgattggtcaac gatgttcagagtatgcgacccaacatctttgtaggagtgagtgagggctcggctcagtac aggaggtggtatttcgagttggtgatcgatcacgtgcatcatttcatgaccggcgagccc tcgcacctgcgggtgggttgggcctccacgagaggttacgccccttacccaggtggagga gagggctgggggggtaacggagtcggagatgatctgtactcctacggcttcgatggactg cacctgtggtcggggcggatctctcgtaccgtagcgtccgtgaagcagcacgtgctgacg tctgatgatgtggtgagctgctgtatggatctgaacgctcccagcatctccttcaggatc aacggccagccggttcagggcatgtttgagaccttcaactccgacgggctgtttttccct gtagtcagcttctccgctggggtcaaggtgcgtttcctgttaggtggtcgtcatggtgaa tttaagttcctgccgccggccggttacgcaccgtgttacgaggctctgctgcctaaagag aagatgagggtggagccagtgaaggaatacaaacgagatgtgggcggagtcagagattta ctgggaaacacccatttcacatcacaggcctcgtttatacctaaacctgtggacacgtct cagaccgtgatgcctcctcacctggagaaggtccgagatcgactcgccgagaacattcat gagctgtggggtacgaacaagatcgagatgggctggtcatacggaaagatccgagaggat aataaacgtcagcatccatgtctggtggatttttccaaactgccagagacagagaggagc tacaacatacagatgtcaacagaaacgctgaagactcttctggctttgggttgtcatgta gttcaggtgagggtcaatgccgaagaagacctgaagaaactcaaactccctaagaactac atgatgtctaacggttataaaccagcgccgctggacctgtctgatgtcaaactgacccca ggtcaggagctgctggtggataaactgacagaaaatgcccacaacgtctgggccaaagat cgcgtcaaacagggctggacctacggcatacagcaggatgtgaagagtaagcgaaaccct cgccttctgccatacgctttactcgacgagcgaaccaagaagtcaaaccgcgacagcctc cgtgaagccatccgcactctgattggatacggctacagtgttgagccgcccgaccaagac gctggtcacgtggtggagcggttgagcatcgataagatccgtttcttccgcgttgagcgg acctatgcggtgaagacggggaagtggtatttcgagtttgaggtggtgacgggtggagac gtgcgggtgggctgggctcggcccggctgtaagcccgacgtggagctcggaacagatgat caagcgtacgtctttgacggacaccggggtcatcgactccacatgggcggtcggctcttc ggtcgctgctggcacgcgggtgatgttgtgggttgtatgatcaacatggaggacaaatcc atgatcttcaccctcaacggagaaatcctgatcactaacaagggctcagaactctgtttt gctgactttgacctcgatgacggtttcattccggtctgcagtttaggactatctcaggtg ggccgtatgaatctggggaaagacgccagcacgtttaaatactacacaatgtgtggactg caggagggctttagacctttcgccgtcaacatgaatcgtgaggtgaccatgtggttcagt aaacgtctgccaaccttcttcaatgtgcccagagaccacagcgacatcacggtcaccagg attgacggtactgtcgacagtccgccctgtctgaaggtcactcataagacgttcgggact cagaacagtaactcagacatggtgttcttcagactgagcatgcccgtagactttcagtcc accttcagaagctccaccagccacatgaacggagtctatgaggaggaaccgctgaaactc agacacaggtatccggtgaagtcaatgaaacactcggaggagagcagaagaatcgactac agcagcatcaccacgtattatcattcagtccgaatattcgcgggtcaggatccgtcctgc gtgtgggtcggttgggtcacccccgactatcattactacagcaacgactttagcctcagc aagaaccgcaccgtgacggtgaccctcggagacgagaggggtcgtgtgcatgagagcgtg aagaggaacaactgctacatggtttggtgtggagatgtcggcagcgcggggcagaccggc ggcagaagtaatgcagatttagagatgggctgtcttatcgatgtggccaccggtctgttg accttcagcgtgaacggcaaagagcttccaacttcacacctggtggagcccagcacaaaa ctctttcccgctgtgttcgtgcgtccgacaagctccagtcttttccagtttgaactgggc aaaatcaagaacaccatgcctctgtcatcagccatctttaagagtgaacacaagaacccg gttcctcagtgtccaccccgtctggacgtccagaccatcagctcggtgctgtggagccgc atgccaaacatattcctgaaggtggagacgtcccggatcagtgagagacacggatggatg gtccagtgtaacgaacccctgcagatgctcgctgtacacatccctgaggagaaccgatgt gtggacatcatggagctttcggagcagaaggaactgcgtaagttccaccatcacacactg aagctttactgcgctctgtgcgctcacggcaacacgcgcgtcgctcacgccctgtgcagc cacctcgaccaatcccagctcctgtacaccatcgacaaccaatacctttccggcatgctg cgcgagggcttctacggcgtcctcatcagcgttcacctggagacggcccgagccgctcgg ctcatgatgaacaacgagttcatcatccccgtcacccccgagacgcgcagcatccagctc tttccagacgcgtccaaacgccaccggccccccggcgtaggtctcagcacgtccctgaag cccaaactcaacttcgcacctccctgtttcatcagcgctaaacgaaaccagcacctctac agccccgagatcccgctggacgtgctgaaagagaaagccatcagcatgctgacggaggcg gttcagggcggaggagatcacatcagagatcccgtgggaggaagcgtggagtatcagttc gtgcccatcctgcgcctcatcagtactctgctcaccatgggcatcctgaccagccgagac gttcacaagatcttactcctcattgagcccaatgtgttcggagaacgcaaggaggagggc tcaagagagacgggggtgaaggaaggtgtgacgggagcggaggagaagactgtcgagact ggagaagaagaaccagtgaagggtagaaaggtcatgaagggactgctggagaagaagtta cctgagtgtgtcaaacgacagatgtgtgatctgcttcattatttctgtgactgtgagttg aggcacaggatcgagtcgatcgtgtcgttctccgacggtttcgtttccaagctgcaattc aaccagaagtttcgctataatgagctgatgctcgcgctcaacatgtctgccgccgtcacc gcaaagaaaaccaaagagtttcgctctcctccacaggaacagattaacatgctgttgaat tttgacatgggcgagggctgtccgtgtccagaggacatacaggaggaactctatgacttt cacactgaactgcggctacactgcggaatcccagtggaggaaccagaggaacatgaagac acgtctcttaaaggtcgtctgctcgcgctggtctataagatcaaaggtcaaccgcagaaa tctgacacacagccccgggagaaagagcaaacagcaccaaccaatctgaaggagctgatc tctcagacgatggtgagctgggctcaggagacacacattcaggatcccgagctggtgcgc gtgatgttcagtctgttgaggagacagtacgacagcatcggcgagctgctgagagccatg aggaagacgtacaccatcagcgccgcctccgtgagcgacaccatccacctgctggcctca ctgggacagatacgctcgctgctgagcgtccgcatgggtaaagaagaggaacagctcatg attgatggcttgagtgacatcatgaataacaaagtcttctaccagcatccgaacctgatg agagttctggggatgcacgagaccgtgatggaggtgatggtaaatgtgctgggaggagga aaatcacaggaaatcgcttttcccaaaatggtagcgagctgctgtcgattcctgtgttac ttctgtcgaatcagtcgagagaatcagaaagccatgttcgatcatttgagttatctgctg gagaacagcagtgttggactggcatctccatccatgagaggatcgacacctttagacgta gcggcttcatccgtcatggataataacagtctggccctcgcgctggaggaacccgacctc gacaaggtggtaacgtatctcgccggctgtgggctgcagagttgttccatgctcgtggct aaaggatatccagatatcagctggaaccctatcgagggtgaacgctacctttccttcctg cggttcgctgtgtttgtcaacggtgagagcgttgaagagaactccagcgtggtggtcaaa cttctgattcgccggccggagtgttttggccccgccctgcgaggagagggtggaaacggg ctgctggcagctatgaatgaggccataaagatctcagagaacccagcgctggatctgccc accacggccccgggacacacgtcagacacgtccactgaaggtgaggaagaggaggaggtg gttcacatggggaacgccattatgtccttctactcggctctgatcgatctgttgggccga tgcgctcccgagatgcacttgatcaataaaggtaaaggtgaagcattgaggattcgtgcc atcctgcgatctctcgtgcccattgaggacctggtgggcatcatcagcatccctctgaaa atgcctgtgctcaataaagatgagagtgtgacagagcctgacgtgtctgccagtttctgt ccggaccacaaggctcccatggtgctgtttttggatcgcgtgtacggcatcgaggatcag agtttcctgctgcatctgttagaggtgggattcctgccggatctgagggccgctgcttta ctcgacacggaatctgtgcggacgaccgaaagcgctctagcaatgaacaggtacatcggt tctgccatgttgcctctgctcacgcgctgcgctcctcacttcaccggcacagaacatcac acagcgctcatcgactcaacgctttacaccatctacagattgtccacatgctgttcgctc accaaagctcagagagacgccatcgaggagtgtttactggctgtctgcaggtatctcagg ccgtccatgttacagcctctcttacgccgactggtgtttgacgtgccgttgttgtccgaa tactgtatgatgcctctgaagttgttatcgaatcattacgagcagaactggaagtattac tgcctcccgtccagctggggcggtcacggtctgccgtctgaagaagagcttctgctcacc aagaagatcttctggggcatctttgattctctctctcagaagacgtacgatcaggagctg tttaaaatggccatgccatgtctgagcgccatcgccggagctcttccacccgattacatc gacccgtcgctcagcaccgcgctggagaaacacgagtctgtagacacgcagggcaacttt gaccccagacccattaacacggccaatgtttgtctgccggagaagctggaatacaccgcc aacaaatacactgaacattgtcatgagaaatgggctgcagagaaggtcatgctgggctgg aaatacggagagaatgtcgacgaaaaattaaaaacacacccaatgatgaggtcctacaaa gctctcacagagaaggagaaagagacgtaccgctggagcgtccgtgagtcactgaagagc atgttggcaatgggctggacaatagaccgaaccaaagaaggagaaatgacctttcagctg agagagattgagaagatgcgcaggacttctcaagtgtctcagggtaacggctacagcccg acacctctagacatgagcaatgtgcctctctcacgagaactccagtcgatggtggaagtt ctggctgaaaactatcacaacatctgggccaagaagaagaagagcgacctcgtagccaaa ggtggcactcatcctcttctggtgccctacgacacactcacagctaaagagaaagtcaaa gatcgtgagagagcccaggatcttttccgctttctgctgattaacggacattcggtcagc aggggattgaaggacatagaacaggactcctcctctatggagaaacgatttgcttataaa tttctcaagaagttgctgaagtacgtggattctgcgcaggaattcatcgctcatctcgag gtcatggctagcagtggacaaaacaacagatctccgcatgaacaggagatcaaattcttt gctaaggtcctcttgcctctcatagatcagtacttcaagaatcactcgctctactttctg tcctcggccaccaagacgctgagcagcagtggatacgcctctaataaagagaaagagatg gtgaccagtctcttctgtaagctggccgctctggttagacacaggatctctctctttgga agtgactccactactatggtcagctgtcttcacatcctcgcacacacattagacaccagg acggtgatgaaatcgggatctgagctggtgaaagcgggtttgaggacgttctttgagaac gcagcagaagatctggagaagacgttggaaaatctgaagttggggaagttcactcactct cgcagtcagatgaagggagtttctcagaacatcaactacaccaccgtcgctcttctgccc atcctcacggctctgtttgaacacatcacagaacatcagttcggctctgatctgctgctg gatgatgtgcaggtgtcctgttatagaattctgtccagtttatattcactgggaactgga aagaacatctatgtggagcggcagttgccggcgttgggcgagtgtctggcgactctggcg ggtgtgatccccgtggcgttcttagagcctccgctgaacaaacacaacatctactctgtg ttcaacacgaagacgtctcgtgaacgtgcagtcgcaggaatgccggagtgtgtggaggac atgtgtcctgagctccctcgtctggacggtctgatgaaggacattaatgacatgtctgag tccggcgctcgatacgcagagatgcctcacgtcatcgaggtggttctgcccatgctctgt aactatctgtcatactggtgggagaaaggaccggagaactgttctgagaacagagtgtcc gtctgcagcaccaccgtcacatcagaacacctcagcatcatcctgggcaacatcctcaag atcctcaacagcaacctgggcatcgatgaagcctcatggatgaaacgcatcgcagtttac gctcagcccatcatcagcaaagcccgcgccgacctgctgaaagctcactttctgcccacg ctggagaagctgaagaagaaaacggtgaaggtggtggcggaggaggagcttctgaaggct gacggcaagggcgacacccaggaggcggagcttctgattctggatgagtttgcggtgctc tgcagagatctgtacgctttctacccgatgctcatccgctacgtggacaacaacaggtct cgttggcttaaggaacccgacggcgattcacacgaactcttcaagatggtggcagagatt tttatcctgtggtgtaaatcacacaatttcaagagagaagagcagaactttgtggttcag aatgagatcaacaacctctcgtttctcactggcgacagtaaaactaagatgtcgaagtcg tatctgcagaagtcaggaggtcaggatcaggaacggaagcacaagaagcgtcgtggtgat ttttactccatccaaacctctctgatcgtggcggcgctgaagaagatgctgcccatcggt ctgaacatgtgtacgccgggcgatcaggagctcatcatgctggccaagactcgacacagc ctgaaggacacagatgaggaggtgaaggaacacatcagacagaatcttcatctccaggag aagtcagatgatcctgctgtacgctggcagctcaatctttataaagatgtgatcgtgaag aacgagggacctccagacccggagaaaacggtcgagcggatccacaggatctcagcggct gtgtttcacctcgagcaggttgaacagccgttaagatcaaagaagtttgtttggcagaag ctgttgtctaaacagaggaagagagctgtggttgcgtgtttcaggatggcaccactgtac aacctgcccaggcacacaattaacaattacttcctgaaatcataccagtgcttttggctg gacagatttctagagagttctgaccgtgacagtctgctcaccatcatcacgaagacacaa ccgaagacagacgaggaggaagatgagatcagagagacacaaccagatcctcttcatcaa ctcatactgcacttcagtcataatgcactgacagaacgcagttctgtggaggatgatcag ctgtacgtggcttacgcagacatgatggcgaagagctgtgctgagaatgaggaagatgat gatgaagagaaagagaaatcatttgaggagaaggagatggagaagcagaagactctctat caacaggctcgacttcatgacagaggagcagcagaaatggtgctacagatgatcagttct agtaaagggcgtttgggtcggatggtcacgttcacactgaaactgggcatctctattctg aacggaggaaacgtgttagttcagcagaaaatgctggactatctgaaggagaaacgagat gtgggatttttcaagagtttgtctggactcatgcagtcatgcagtgttctggatctgaac gcattcgagcgtcagaacaaagctgaaggtttggggatggtcactgaagaaggttgcatc aacatgagagaacggggttcgaaagttcttcagaatgatgagtttaccaaagatcttttc aggtttctgcagctgttgtgtgaaggacataataacgattttcagaacttcctcagaaca caaacaggaaacacgaccacagttaatatcatcataagcactgtggactatctgctcaga ctgcaggaatccatcagtgatttttactggtattactctggtaaagacgtcatggataaa gcggggcagcgtaatttctccaaagctcttgccgtagcaaaacagatcttcaattcactc actgaatacatccagggtccgtgtattgggaatcagcagagtttggctcacagcagactc tgggatgctgttgttggatttcttcatgtttttgctaacatgcaaatgaagctgtcacag gactccagtcagatcgagctgttgaaggagctgttggatctacagaaggatatgattgtc atgatgttgtcacttctggaaggtaatgttgtgaacgggactatcggtaaacagatggtg gacactctcgtggaatcctccagcaacgtggagatgatcctgaagttcttcgacatgttc ctcaagctgaaagatttgaccacctccgacagcttcaaagagcacgaccccgaccgcaaa ggagtcatctccaagaaagagtttcagaagtccatggaaagccagaagcagtactcgcaa tccgagatcgatttcctgctgtcctgcgccgaggccgacgagaacgacatgttcaactac gaggagtttgttgaacgcttccatgaaccggccaaggacatcggtttcaacatggcggtc ctgctcaccaacctatcagagcacatgccccacgacgcccgtctcgccaccttcctgaac ctggctgaaagcgtcctgaactactttgagcccttcctgggccgcatcgaaatcataggt ggagctaagagaatcgagagggtttacttcgagatcagcgagtccagcagaactcagtgg gaaaaaccgcaggtcaaggagtccaagcgacagttcatcttcgatgtcgtcaacgagggc ggagaatccgagaagatggagctgttcgtcaacttctgcgaggacaccattttcgagatg cagctggcgtctctgatctccgagccggacgcggcggagaggccggaggaggacgacaat gacgacgcactgagcgtgaccgagaaccaagaggaggaggaagacaacgcggcgttggag tcgtcctcggcgttcactctggcctgcgtctccacaaggaaaagtctgtcgaacctcaga cggatgctgtcgctgaaaagcattagaagacagtaccgaaagctgaggaagatgagcgtg aaggagatgatacgaggcttcttctgcttcttctggacgatcttcgttggcacgttccgc ttcctctacaatctcctgtggggtttctttcacatcctctggtccaccctgttcggcgga ggtctggtggaaggagccaagaacatgaaggtgacggatattctggggaacatgcccgat cccacgcagttcgggatccatggcgacgttctggagatggagaagcttgaatactgtgac gcgtctgaggcatccgagctggggtgccagtcggtcggtgagcgggcggagatggacctg atgtcagaactgatgaacgttcagcccaggagagagggaggcaaacacgggatggagccg ggactgggagacgtgtctgaggtggtcggggtggacgctccttctttggccagcgctgtt caccagaagaaagctcaggaagctgcgatgaacgctgcagagtctgaagccaaatgggag tccgagaaggccgatgttgaagacaaagagaagacatatcagggcaggagagatgaacct gtgtcggggccagcggcatataaagagaggaagcctgtgaagaacagaggtggactgaag aaagaaacgcctgacgcttgcatggcttcgtttttagccggtctggacgtctatcagact aaaatgctgaattatctggctagaaacttttacaacctgcgttttctggcactgtttgtg gcttttgccatcaacttcattctgctcttctacaaggtgacaggcgaggactctgatgat ttggatccgtgggttcggcgtggtggtgctggtgctggtgatgatgatggtgttgtggag tattttgttcttcaggagagcagtggttatatggccccgactctccgcttcctcgccgtc atgcacacgctcatctcctctctctgtgtgctgggatattattatctgaaggttccgctg gtggtcttcaagcgtgagaaggagattgcacgtaaactggagtttgatgggctgtacatc actgagcagccgtcagatgatgatataaaaggacagtgggacagactcgtcatcaacaca ccatctttccccaacaactactgggacaaatttgtgaaacgcaaggtgataaacaagtac ggagatctgtacggtgccgagcggatcgcagaactgctgggtttggataaaagcgctctg gattttaatcccaccgaagacgccgttatgaaagacgcctcgctgctgtcctggttaagc tccatcgacaccaagtatcacgtgtggaagttgggcgtagtcttcacagataactctttc ttgtatctggtctggtacaccacgatgtctgtactgggacattataataacttcttcttc gccgctcatctgttggacatcgccatgggcttcaaaaccctgcggaccatcctgtcatcg gtcacacacaacggcaaacagttggtgttgacggtcggtctgctggctgtggttgtctat ctctacaccgtcgtggctttcaactttttccgcaagttctacaacaagagttcagacgag gacgagcccgacatgaagtgtgatgacatgatgacttgttacctgtttcacatgtacgtt ggcgtccgtgctggtggaggtattggagatgaaatcgaggaccccgcgggtgacccgtat gaactctaccgcattctttttgacatcacctttttcttctttgtgattgttatcctgctg gctatcatacaaggtttgatcatcgatgcgttcggagagttgagagatcagcaggaacag gtcaaagaagacatggagactaaatgtttcatctgtggaatcgggaacgagtatttcgac acgacgccgcatggctttgagactcacacgctgcaggagcacaatcttgccaactaccta tttttcttgatgtacctgataaacaaggacgagaccgaacacaccggacaggagtcgtac gtatggaagatgtatcaggagagatgttgggatttctttcccgccggtgattgtttccgt aagcagtatgaagatcagctgggctag

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