Tetrahymena thermophila: TTHERM_00325580
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Entry
TTHERM_00325580 CDS
T01020
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
tet
Tetrahymena thermophila
Pathway
tet00280
Valine, leucine and isoleucine degradation
tet00640
Propanoate metabolism
tet00785
Lipoic acid metabolism
tet01100
Metabolic pathways
tet01110
Biosynthesis of secondary metabolites
tet01210
2-Oxocarboxylic acid metabolism
Module
tet_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tet00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
TTHERM_00325580
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TTHERM_00325580
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TTHERM_00325580
Enzymes [BR:
tet01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
TTHERM_00325580
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
PTHB1_hp
Motif
Other DBs
NCBI-GeneID:
7833132
NCBI-ProteinID:
XP_001026420
TGD:
TTHERM_00325580
UniProt:
I7MJD5
LinkDB
All DBs
AA seq
431 aa
AA seq
DB search
MIKNFRQVCRFALYQSALKTNSFQNLSKRAFCYVKHHKTFNDNEEIYTHQLSAASQPDTI
PTFRVIDLQGSVLAPQYENIPDEILNKIFDTMVQVEEIDTILNMTQRQGKISFYMPSFGE
QATTVGVGAALEFEDLVFPQYREQGTIIYRGYTVRDMLNQCIGNIHDLGKGRQMPVHYGS
KALNFVTVSSPLTTQVPQASGAGYGYRLRGENKVAATYFGEGAASEGDWHAALNFAATLS
CQTLFLCRNNKYAISTPVVDQYRGDGIAGKSIGYGIKTYRVDGNDALAVYHTVKEARNYI
VTNKAPAFIEFMTYRIGDHSTSDHSVMYRTEDEISSWKSTNNPITRLGLYLKKSGRRVFD
EAKDKEVRAAIKKDIIAALKEANEQKLPAWNTLFEDVYDQLTPNLKEQKEELRQHLNEYG
EHYNLQKFASN
NT seq
1296 nt
NT seq
+upstream
nt +downstream
nt
atgatcaagaatttcagacaagtttgtagattcgctttatatcaaagcgctttgaagacc
aattccttctaaaatttaagcaagcgtgctttctgctatgtcaagcatcataaaaccttc
aatgataacgaagaaatttacactcattaactcagcgcagcttctcaaccagatactatt
cccacatttagagttattgatttgtaaggaagtgttcttgctccccaatatgaaaatatt
cctgatgaaatcttgaacaagatttttgacacaatggttcaagttgaagaaatagatact
atcttaaatatgactcaaagataaggtaagatttctttctacatgccttcctttggtgaa
taagccactactgttggtgttggtgccgctcttgaatttgaagatttagttttccctcaa
tacagagaataaggtactattatttacagaggatatactgttagagatatgcttaactaa
tgtattggtaacattcacgatcttggtaagggtcgttaaatgcctgttcactatggttct
aaggctcttaattttgttactgtgtcttcccctttaacaacttaggtaccttaagcaagt
ggtgctggttatggatacagattgagaggcgaaaataaagtagctgctacctattttggt
gaaggtgctgcttctgaaggtgactggcatgctgctttgaactttgctgctactttgtca
tgctaaactcttttcctttgcagaaacaataaatatgctatctcaactccagtagttgat
taatacagaggtgatggtattgcaggtaagagtattggttatggaattaaaacttacaga
gttgatggtaatgacgctcttgctgtttatcatactgttaaggaagctagaaattatatt
gtaactaataaagctcctgcatttattgaatttatgacttacagaatcggtgatcatagc
acaagtgatcactctgttatgtacagaacagaagatgaaatctcttcatggaaatcaact
aacaaccctatcaccagattaggtctctacttgaaaaagagtggcagaagagtcttcgat
gaagccaaggataaggaagtacgtgctgctataaagaaagatattattgctgcattaaag
gaagcaaacgaataaaagttacctgcttggaataccttatttgaagatgtttatgactaa
ctcactcctaatttaaaggaacaaaaggaagaacttagataacatttaaatgaatacggt
gaacactacaacttacaaaagtttgctagcaattga
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