KEGG   Trachypithecus francoisi (Francois's langur): 117064180
Entry
117064180         CDS       T07225                                 
Symbol
PPP3CA
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn04010  MAPK signaling pathway
tfn04020  Calcium signaling pathway
tfn04022  cGMP-PKG signaling pathway
tfn04114  Oocyte meiosis
tfn04218  Cellular senescence
tfn04310  Wnt signaling pathway
tfn04360  Axon guidance
tfn04370  VEGF signaling pathway
tfn04380  Osteoclast differentiation
tfn04625  C-type lectin receptor signaling pathway
tfn04650  Natural killer cell mediated cytotoxicity
tfn04658  Th1 and Th2 cell differentiation
tfn04659  Th17 cell differentiation
tfn04660  T cell receptor signaling pathway
tfn04662  B cell receptor signaling pathway
tfn04720  Long-term potentiation
tfn04724  Glutamatergic synapse
tfn04728  Dopaminergic synapse
tfn04921  Oxytocin signaling pathway
tfn04922  Glucagon signaling pathway
tfn04924  Renin secretion
tfn05010  Alzheimer disease
tfn05014  Amyotrophic lateral sclerosis
tfn05020  Prion disease
tfn05022  Pathways of neurodegeneration - multiple diseases
tfn05031  Amphetamine addiction
tfn05152  Tuberculosis
tfn05163  Human cytomegalovirus infection
tfn05166  Human T-cell leukemia virus 1 infection
tfn05167  Kaposi sarcoma-associated herpesvirus infection
tfn05170  Human immunodeficiency virus 1 infection
tfn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117064180 (PPP3CA)
   04310 Wnt signaling pathway
    117064180 (PPP3CA)
   04370 VEGF signaling pathway
    117064180 (PPP3CA)
   04020 Calcium signaling pathway
    117064180 (PPP3CA)
   04022 cGMP-PKG signaling pathway
    117064180 (PPP3CA)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    117064180 (PPP3CA)
   04218 Cellular senescence
    117064180 (PPP3CA)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    117064180 (PPP3CA)
   04650 Natural killer cell mediated cytotoxicity
    117064180 (PPP3CA)
   04660 T cell receptor signaling pathway
    117064180 (PPP3CA)
   04658 Th1 and Th2 cell differentiation
    117064180 (PPP3CA)
   04659 Th17 cell differentiation
    117064180 (PPP3CA)
   04662 B cell receptor signaling pathway
    117064180 (PPP3CA)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    117064180 (PPP3CA)
   04921 Oxytocin signaling pathway
    117064180 (PPP3CA)
   04924 Renin secretion
    117064180 (PPP3CA)
  09156 Nervous system
   04724 Glutamatergic synapse
    117064180 (PPP3CA)
   04728 Dopaminergic synapse
    117064180 (PPP3CA)
   04720 Long-term potentiation
    117064180 (PPP3CA)
  09158 Development and regeneration
   04360 Axon guidance
    117064180 (PPP3CA)
   04380 Osteoclast differentiation
    117064180 (PPP3CA)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117064180 (PPP3CA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117064180 (PPP3CA)
   05170 Human immunodeficiency virus 1 infection
    117064180 (PPP3CA)
   05163 Human cytomegalovirus infection
    117064180 (PPP3CA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117064180 (PPP3CA)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    117064180 (PPP3CA)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117064180 (PPP3CA)
   05014 Amyotrophic lateral sclerosis
    117064180 (PPP3CA)
   05020 Prion disease
    117064180 (PPP3CA)
   05022 Pathways of neurodegeneration - multiple diseases
    117064180 (PPP3CA)
  09165 Substance dependence
   05031 Amphetamine addiction
    117064180 (PPP3CA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117064180 (PPP3CA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:tfn01009]
    117064180 (PPP3CA)
Enzymes [BR:tfn01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     117064180 (PPP3CA)
Protein phosphatases and associated proteins [BR:tfn01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     117064180 (PPP3CA)
SSDB
Motif
Pfam: Metallophos
Other DBs
NCBI-GeneID: 117064180
NCBI-ProteinID: XP_033034294
LinkDB
Position
Unknown
AA seq 521 aa
MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHLMKEGRLEESV
ALRIITEGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYV
DRGYFSIECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMD
AFDCLPLAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFG
NEKTQEHFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFP
SLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEK
VTEMLVNVLNICSDDELGSEEDGFDGATAAARKEVIRNKIRAIGKMARVFSVLREESESV
LTLKGLTPTGMLPSGVLSGGKQTLQSATVEAIEADEAIKGFSPQHKITSFEEAKGLDRIN
ERMPPRRDAMPSDANLNSINKALTSETNGTDSNGSNSSNIQ
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgtccgagcctaaggcaattgatcccaagttgtcgacgaccgacagggtggtgaaagct
gttccatttcctccaagtcaccggcttacagcaaaagaagtgtttgataatgatggaaaa
cctcgtgtggatatcttaaaggcacatcttatgaaggagggaagactggaagagagtgtt
gcattgagaataataacagagggtgcatcaattcttcgacaggaaaaaaacttgctggat
attgatgcgccagtcacagtttgtggggacattcatggacaattctttgacttgatgaag
ctctttgaagttgggggatctcctgccaacactcgctacctcttcttaggggactatgtt
gacagagggtacttcagtattgaatgtgtgctgtatttgtgggccttgaaaattctttac
cccaaaacactgtttttacttcgtggaaatcatgaatgtagacatctaacagagtatttc
acatttaaacaagaatgtaaaataaagtattcagagcgcgtatatgacgcctgtatggat
gcctttgactgccttcccttggctgccctgatgaaccaacagttcctgtgtgtacatggt
ggcttgtctccagagattaacaccttagatgatatcagaaaattagaccgattcaaagaa
ccacctgcatatggacctatgtgtgatatcctgtggtcagaccccctggaagattttgga
aatgagaagactcaggaacatttcactcacaacacagtcagggggtgttcgtacttctac
agttacccggctgtatgtgaattcttacagcacaataacttgttatctatacttcgagcc
catgaagcccaagatgcagggtaccgcatgtacaggaaaagccaaacaacagggttccct
tctctaatcacaattttttcagcaccaaattacttagatgtatacaataacaaagctgca
gtattgaagtatgagaacaatgttatgaatatcaggcaattcaactgttctcctcatcca
tactggcttccaaatttcatggatgtttttacttggtccctgccttttgttggggaaaaa
gtgactgagatgctggtaaatgtcctcaacatctgctctgatgatgagctagggtcagaa
gaagatggatttgatggtgcaacagctgcagcccggaaggaggtgataaggaacaagatc
cgagcaataggcaaaatggccagagtgttctcagtgctcagagaagagagtgagagtgtg
ctgacgctgaaaggcttgaccccgactggcatgctccccagcggagtactttctggaggg
aagcaaaccctacaaagcgctactgttgaggctattgaggctgatgaagctatcaaagga
ttttcaccacaacataagatcactagcttcgaggaagccaagggcttagaccgaattaat
gagaggatgccgcctcgcagagatgccatgccctctgacgccaaccttaactccatcaac
aaggctctcacctcagagactaacggcacggacagcaatggcagtaatagcagcaatatt
cagtga

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