Trachypithecus francoisi (Francois's langur): 117070145
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Entry
117070145 CDS
T07225
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn01521
EGFR tyrosine kinase inhibitor resistance
tfn01522
Endocrine resistance
tfn04010
MAPK signaling pathway
tfn04014
Ras signaling pathway
tfn04015
Rap1 signaling pathway
tfn04066
HIF-1 signaling pathway
tfn04068
FoxO signaling pathway
tfn04081
Hormone signaling
tfn04114
Oocyte meiosis
tfn04140
Autophagy - animal
tfn04144
Endocytosis
tfn04150
mTOR signaling pathway
tfn04151
PI3K-Akt signaling pathway
tfn04152
AMPK signaling pathway
tfn04211
Longevity regulating pathway
tfn04213
Longevity regulating pathway - multiple species
tfn04510
Focal adhesion
tfn04520
Adherens junction
tfn04550
Signaling pathways regulating pluripotency of stem cells
tfn04730
Long-term depression
tfn04913
Ovarian steroidogenesis
tfn04914
Progesterone-mediated oocyte maturation
tfn05200
Pathways in cancer
tfn05202
Transcriptional misregulation in cancer
tfn05205
Proteoglycans in cancer
tfn05214
Glioma
tfn05215
Prostate cancer
tfn05218
Melanoma
tfn05224
Breast cancer
tfn05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117070145 (IGF1R)
04014 Ras signaling pathway
117070145 (IGF1R)
04015 Rap1 signaling pathway
117070145 (IGF1R)
04066 HIF-1 signaling pathway
117070145 (IGF1R)
04068 FoxO signaling pathway
117070145 (IGF1R)
04151 PI3K-Akt signaling pathway
117070145 (IGF1R)
04152 AMPK signaling pathway
117070145 (IGF1R)
04150 mTOR signaling pathway
117070145 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
117070145 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
117070145 (IGF1R)
04140 Autophagy - animal
117070145 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
117070145 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117070145 (IGF1R)
04520 Adherens junction
117070145 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
117070145 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
117070145 (IGF1R)
04914 Progesterone-mediated oocyte maturation
117070145 (IGF1R)
09156 Nervous system
04730 Long-term depression
117070145 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
117070145 (IGF1R)
04213 Longevity regulating pathway - multiple species
117070145 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117070145 (IGF1R)
05202 Transcriptional misregulation in cancer
117070145 (IGF1R)
05205 Proteoglycans in cancer
117070145 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
117070145 (IGF1R)
05214 Glioma
117070145 (IGF1R)
05218 Melanoma
117070145 (IGF1R)
05215 Prostate cancer
117070145 (IGF1R)
05224 Breast cancer
117070145 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117070145 (IGF1R)
01522 Endocrine resistance
117070145 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117070145 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tfn04090
]
117070145 (IGF1R)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
117070145 (IGF1R)
Protein kinases [BR:
tfn01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
117070145 (IGF1R)
CD molecules [BR:
tfn04090
]
Proteins
117070145 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
117070145
NCBI-ProteinID:
XP_033044766
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKSGSGEGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDLEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctctggagaagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccgggcattgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctaccttcac
atcctgctcatctccaaggccgaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacttgcttttgttccgagtggctggcctagagagcctcggagacctgttc
cccaacctcacggtaatccgcggctggaaactcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcagtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccaggtaccatggaggagaagccgatgtgcgagaagaccaccatcaacaatgaa
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcatgtggg
aagagggcatgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgtgtagcttgccgccactactactacgccggtgtctgc
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgagggtttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctcaggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagagaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgacgggggaataacattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtcctcgacaaccagaacttgcagcaactatgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattgtgtgtttcggaaatttac
cgcatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgatgtcctgcatttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccttttaagaatgtcacggagtatgatggg
caggatgcctgcggctccaacagctggaacatggtggacgtggacctcccacccaacaag
gacgtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaacgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagca
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgcggacggcaccatcgacatt
gaggaggtcacagagaacccgaagactgaggtgtgtggtggagagaaagggccttgctgc
gcctgccccaaaactgaagctgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gatgtcatgcaagtggccaacaccaccatgtccagccgaagcaggaacaccacggcggca
gacacctacaacattacagatctggaagagctagagacagagtaccctttctttgagagc
agagtggataataaggagagaactgtcatttctaaccttcgacctttcacattgtaccgc
attgatatccacagctgcaaccatgaggctgagaaactgggctgcagcgcctccaacttt
gtctttgcaaggactatgcccgcagaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccagaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatataggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaatttcatccatctgatcatcgctctg
cctgtcgctgtcctgttgatcgtgggagggctggtgattatgctgtacgtcttccataga
aagagaaataacagcaggctggggaatggagtgctgtacgcgtctgtgaacccagagtac
ttcagcgctgcagatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcacc
atgagccgagaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagacgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcgagc
atgcgtgaaaggatcgagtttctcaacgaggcttctgtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggtgtggtgtcccagggccagccaacgctggtcatcatggaa
ctgatgacacggggtgatctcaaaagttatctccggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgattcagatggctggagagattgca
gacggcatggcatacctgaacgccaacaagttcgtccacagagaccttgctgcccggaat
tgcatggtagccgaggatttcaccgtcaaaattggagattttgggatgacgcgagatatc
tatgaaacagactattaccggaaaggagggaaagggctgttgcccgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtt
gtcctctgggagatcgccacactggccgagcagccctaccagggcttgtccaacgagcaa
gtccttcgcttcgtcatggagggcggccttctggacaagccagacaactgccccgacatg
ctgtttgaattgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccagaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggctgagaacggccccggccctggagtgctggtcctccgtgccagcttt
gatgagagacagccttacgcacacatgaacggtggccgcaagaacgagcgggccttgccg
ctgccccagtcttcgacctgctga
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integrated database retrieval system
