Trachypithecus francoisi (Francois's langur): 117074608
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Entry
117074608 CDS
T07225
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn00010
Glycolysis / Gluconeogenesis
tfn00620
Pyruvate metabolism
tfn01100
Metabolic pathways
tfn01200
Carbon metabolism
tfn01230
Biosynthesis of amino acids
tfn04910
Insulin signaling pathway
tfn04930
Type II diabetes mellitus
tfn04932
Non-alcoholic fatty liver disease
tfn04950
Maturity onset diabetes of the young
Module
tfn_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
tfn_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
117074608 (PKLR)
00620 Pyruvate metabolism
117074608 (PKLR)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
117074608 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
117074608 (PKLR)
04950 Maturity onset diabetes of the young
117074608 (PKLR)
04932 Non-alcoholic fatty liver disease
117074608 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
tfn04147
]
117074608 (PKLR)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
117074608 (PKLR)
Exosome [BR:
tfn04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
117074608 (PKLR)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
117074608
NCBI-ProteinID:
XP_033052116
LinkDB
All DBs
Position
Unknown
AA seq
574 aa
AA seq
DB search
MSIQENIPALQRWSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQELGTAFFQQQQ
LPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS
HGSHEYHAESIANVREAVESFAASPLGYRPVAIALDTKGPEIRTGILQGGPESEVELVKG
SQVLVTVDPAFRTRGNANTVWVDYPNVVGVVPVGGRIYIDDGLISLVVQKIGPEGLVTQV
ENGGVLGSHKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAA
LGPEGQGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS
AQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESG
KLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcgatccaggagaacataccagcccttcagcgctggtcatgggtctctaagtcccaa
agagacttagccaagtccatcctgattggggctccaggagggccagcggggtatcttcgg
cgggctagtgtggcccaactgacccaggagctgggcactgccttcttccagcagcagcag
ctgccagctgctatggcagacaccttcctggaacacctctgcctactggacattgactcc
gagcccgtggctgctcgcagtaccagcatcatcgccaccatcgggccggcatctcgctcc
gtggagcgcctcaaggagatgatcaaggccgggatgaacattgcgcgactcaatttctcc
catggctcccacgagtaccacgctgaatccatcgccaacgtccgggaggcggtggagagc
tttgcagcttccccgctcggctaccggcccgtggccatcgccctggacaccaagggaccg
gagatccgcactgggatcctgcaggggggtccggagtcggaagtggagctggtgaagggc
tcccaggtgctggtgactgtggaccccgcgtttcggacgcgggggaacgcgaacaccgtg
tgggtggactaccccaatgttgtcggggtcgtgccggtggggggccgcatctacattgac
gacgggctcatctccctagtggtccagaaaatcggcccagagggactggtgacccaagtg
gagaacggtggcgtcctgggcagccataagggcgtgaacttgccgggggcccaggtggac
ttgcccgggctgtccgagcaggacgtccgggacctgcgcttcggggtggagcatggagtg
gacatcgtgtttgcctcctttgtgcggaaagccagcgacgtggctgctgtcagggctgct
ctggggccagaaggacagggcatcaagatcatcagcaaaattgagaatcacgaaggcgtg
aagaggtttgatgaaatcctggaggtgagcgatggcatcatggtggcacggggggaccta
ggcatcgagattccagcagagaaggtttttctggctcagaagatgatgattgggcgctgc
aacttggcgggcaagcctgttgtctgtgccacacagatgctggagagcatgattaccaag
ccccggccaacgagggcagagacaagtgatgtggccaatgctgtgctagatggggccgac
tgcatcatgttgtcaggggagactgccaaaggcaacttccctgtggaagccgtgaagatg
cagcatgcgattgcccgggaggcagaggctgcagtgtaccaccggcagctgtttgaggag
ctacgtcgggcagcaccactgagccgtgatcccactgaggtcaccgccattggcgccgtg
gaggctgccttcaagtgctgtgctgctgccatcatcgtactgaccacaactggccgctca
gcccagcttctgtctcggtaccgacctcgggcagcagtcattgctgtcacccgctctgcc
caagctgcccgccaggtccacttatgccgaggcgtcttccccttgctttaccgtgaacct
ccagaagccatctgggcagatgacgtagatcgccgggtgcaatttggcattgaaagtgga
aagctccgtggcttcctccgtgttggagacctggtgattgtggtgacaggctggcgacct
ggctccggctacaccaacatcatgcgggtgctgagcatatcctga
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