KEGG   Trachypithecus francoisi (Francois's langur): 117075952
Entry
117075952         CDS       T07225                                 
Symbol
GSTM4
Name
(RefSeq) glutathione S-transferase Mu 4 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn00480  Glutathione metabolism
tfn00980  Metabolism of xenobiotics by cytochrome P450
tfn00982  Drug metabolism - cytochrome P450
tfn00983  Drug metabolism - other enzymes
tfn01100  Metabolic pathways
tfn01524  Platinum drug resistance
tfn05200  Pathways in cancer
tfn05204  Chemical carcinogenesis - DNA adducts
tfn05207  Chemical carcinogenesis - receptor activation
tfn05208  Chemical carcinogenesis - reactive oxygen species
tfn05225  Hepatocellular carcinoma
tfn05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    117075952 (GSTM4)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    117075952 (GSTM4)
   00982 Drug metabolism - cytochrome P450
    117075952 (GSTM4)
   00983 Drug metabolism - other enzymes
    117075952 (GSTM4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117075952 (GSTM4)
   05204 Chemical carcinogenesis - DNA adducts
    117075952 (GSTM4)
   05207 Chemical carcinogenesis - receptor activation
    117075952 (GSTM4)
   05208 Chemical carcinogenesis - reactive oxygen species
    117075952 (GSTM4)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    117075952 (GSTM4)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    117075952 (GSTM4)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    117075952 (GSTM4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:tfn02000]
    117075952 (GSTM4)
Enzymes [BR:tfn01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     117075952 (GSTM4)
Transporters [BR:tfn02000]
 Other transporters
  Pores ion channels [TC:1]
   117075952 (GSTM4)
SSDB
Motif
Pfam: GST_N GST_C GST_C_3 GST_N_2 GST_N_3 Bromo_TP Tom37
Other DBs
NCBI-GeneID: 117075952
NCBI-ProteinID: XP_033054706
LinkDB
Position
Unknown
AA seq 248 aa
MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
PYLIDGTHRITQSNAIMRYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF
EKLKPEYLEGLPTMMQHFSQFLGKRPWFVGDKVMGACDGDTRDLSYILCYGDSSPHILGL
LQISFVDFLAYDVLDLHCIFEPKCLDAFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYT
RVAVWGNK
NT seq 747 nt   +upstreamnt  +downstreamnt
atgtccatgacactggggtactgggacatccgtgggctggcccacgccatccgcctgctc
ctggaatacacagactcaagctatgaggaaaagaagtacacaatgggggacgctcctgac
tatgacagaagccagtggctgaatgaaaaattcaagctgggcctggactttcccaatctg
ccctacttgattgatgggactcacaggatcacccagagcaatgccatcatgcgctacatt
gcccgcaagcacaacctgtgtggggagacagaagaggagaagattcgtgtggacatttta
gagaaccaggctatggacgtctccaatcagctggccagagtctgctacagccctgatttt
gagaaactgaagccagaatacttggagggacttcctacaatgatgcagcacttctcacag
ttcctggggaagaggccatggtttgttggagacaaggtaatgggggcatgtgatggggac
actagagatttgtcatacatcctatgttacggagattccagcccacacattcttggcctt
ctgcagatctcctttgtagatttcctcgcctatgatgtccttgacctccactgtatattt
gagccgaagtgcttggacgccttcccaaatctgaaggacttcatctcccgatttgagggc
ttggagaagatctctgcctacatgaagtccagccgcttcctcccaaaacctctgtacaca
agggtggctgtctggggcaacaagtaa

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