Trachypithecus francoisi (Francois's langur): 117076194
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Entry
117076194 CDS
T07225
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn04217
Necroptosis
tfn04380
Osteoclast differentiation
tfn04620
Toll-like receptor signaling pathway
tfn04621
NOD-like receptor signaling pathway
tfn04630
JAK-STAT signaling pathway
tfn04658
Th1 and Th2 cell differentiation
tfn04659
Th17 cell differentiation
tfn05145
Toxoplasmosis
tfn05160
Hepatitis C
tfn05161
Hepatitis B
tfn05162
Measles
tfn05164
Influenza A
tfn05165
Human papillomavirus infection
tfn05167
Kaposi sarcoma-associated herpesvirus infection
tfn05168
Herpes simplex virus 1 infection
tfn05169
Epstein-Barr virus infection
tfn05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117076194 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
117076194 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
117076194 (TYK2)
04621 NOD-like receptor signaling pathway
117076194 (TYK2)
04658 Th1 and Th2 cell differentiation
117076194 (TYK2)
04659 Th17 cell differentiation
117076194 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
117076194 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
117076194 (TYK2)
05160 Hepatitis C
117076194 (TYK2)
05171 Coronavirus disease - COVID-19
117076194 (TYK2)
05164 Influenza A
117076194 (TYK2)
05162 Measles
117076194 (TYK2)
05168 Herpes simplex virus 1 infection
117076194 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
117076194 (TYK2)
05169 Epstein-Barr virus infection
117076194 (TYK2)
05165 Human papillomavirus infection
117076194 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117076194 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117076194 (TYK2)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117076194 (TYK2)
Protein kinases [BR:
tfn01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117076194 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
117076194
NCBI-ProteinID:
XP_033055305
LinkDB
All DBs
Position
Unknown
AA seq
1190 aa
AA seq
DB search
MPLRHRGTTRGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSLTAEEICIHI
AHKVGITPPCFNLFALFDAQAQVWLPPNYILEIPRDASLMLYFRMRFYFRNWHGMNPQEP
AVYRCGPPGTEASSDQTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELSSEEEIHHFK
NESLGMAFLHLCHLALRRGVPLEEVAKKTSFKDCIPLSFRRQIRQHSALTRLRLRNVFRR
FLQDFQPDRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPCYIRDSGEAP
TDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEGSSGGSGRNPQASLSGKKAKAHK
AIGQPVDRLREPLWAYFCDFRDITHVVLKERCVSIHRQDNKCLELSLPSRAAALSFVSLV
DGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVQAKLRPEDGLYLIHWSTSHP
YRLILTVAQRSQAPDGTQSLRLRKFPIEQQAGAFVLEGWGRSFPSIRELGAALQGCLLRA
GDDCFSLRRCCLPQPGETSNLIIMRGARASTRTLNLSQLSFHRVDQKEITQLSHLGQGTR
TNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSHHDIALAFYETAS
LMSQVSHVHLAFVHGICVRGPENIMVTEYMEHGPLDVCLRREQGHVPMAWKMVVAQQLAS
ALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLAALSREERVERIPWMA
PECLPGGPNSLSIAMDKWGFGATLLEICFDGEAPLQSLSSSEKEHFYQRQHRLPEPSCPE
LATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVLIVNPDSSASDPTVFHKRYL
KKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRLGWKQEIEILRTLYHE
HIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHAQ
HYIHRDLAARNVLLDNDKLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECK
FYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGITQGQMTVLRLTELLERGERLPRP
DKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFSVC
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgcgccatcgggggacgaccaggggcagcaagcccgttggggatggagcccag
cccatggctgccatgggaggcctgaaggtgcttctgcactgggctggtccaggcggcgga
gagccctgggtcactttcagcgagtcatcgctgacagctgaggaaatctgcatccacatc
gcacataaagtcggtatcactcctccttgtttcaatctcttcgccctcttcgatgctcag
gcccaagtctggttgcccccaaactacatcctagagatccccagagatgcaagcctgatg
ctgtatttccgcatgaggttttatttccggaactggcatggcatgaatcctcaggagccg
gctgtgtaccgttgtgggcccccaggaaccgaggcatcctcagatcagacagcacagggg
atgcaactcctggacccagcctcatttgagtacctctttgagcagggcaagcatgagttt
gtgaatgacgtggcatcactgtgggagctgtcgagcgaggaggagatccaccactttaag
aatgagagcctaggcatggcctttctgcatctctgtcaccttgctctccgccgtggtgtc
cccctggaggaggtggccaagaagaccagcttcaaggactgtatcccactctccttccgt
cggcagatccggcagcacagcgccctcacccggctgcgccttcggaacgtcttccgcagg
ttcctgcaggacttccagccagacagactctcccagcagatggtcatggtcaaatacctg
gccacacttgaacggctggcaccccgctttggcacagagcgtgtgcctgtgtgccacctg
aggctgctggcccaggcagagggggagccctgctacatccgggacagtggggaggcccct
acagaccccggccccgagtctgctgctggacccccaacccatgaggtgctggtgacaggc
actggtggcatccagtggtggccagtacaggaggaggtgaacaaggaggagggttctagt
ggcggcagcggcaggaacccccaagccagcctgtctgggaagaaggccaaggcacacaag
gcaatcggccagccggtggacaggctgcgggagccactgtgggcctacttctgcgacttc
cgggacatcacccacgtggtgctgaaagagcgctgtgtcagcatccaccggcaggacaac
aagtgcctggagctgagcctgccttcccgggctgcggcgctgtccttcgtgtcgctggtg
gacggctatttccgcctgacggccgactccagccactacctgtgccacgaggtggctccc
ccacggctggtgatgagcatccaggatgggatccatggacccctgctggagccgtttgtg
caggccaagctgcggcccgaggacggcctgtacctcattcactggagcaccagccacccc
taccgcctgatcctcacagtggcccagcgtagccaggcaccagacggcacacagagcttg
cggctccggaagttccccattgagcagcaggctggggcctttgtgctggagggctggggc
cggtccttccccagcattcgggaacttggggccgccttgcagggctgcttgctgagggcc
ggggacgactgcttctctctgcgtcgctgttgcctgccccaaccaggagaaacctccaac
ctcatcatcatgcggggggctcgggccagcaccaggacactcaacctcagccagctcagc
ttccaccgggttgaccagaaggagatcacccagctgtcccacttgggccagggcacgagg
accaacgtgtacgagggccgcctgcgagtggagggcagtggggaccctgaggagggcaag
atggacgatgaggaccccctcgtccctggcagggaccgtgggcaggagctacgagtggtg
ctcaaagtgctggacccgagtcaccatgacatcgccctggccttctatgagacagccagc
ctcatgagccaggtctcccacgtgcacctggcctttgtgcacggcatctgtgtgcgcggc
cctgaaaatatcatggtgacagagtacatggagcacggacccctggacgtgtgtctacgg
agggagcagggccatgtgcccatggcttggaagatggtggtggcccagcagctggccagc
gccctcagctacctggagaacaagaacctggtacatggtaatgtgtgtggccggaacatc
ctgctggctcggctggggctggcagagggcacgagccccttcatcaagctgagtgatccc
ggcgtgggcctggctgccctctccagggaggagcgggtggagcggatcccctggatggcc
cccgaatgcctcccaggtgggcccaacagcctaagcattgccatggacaagtgggggttt
ggtgccaccctcctggagatctgctttgatggagaggcccctctgcagagcctcagctcc
tccgagaaggagcatttctaccagaggcagcaccggctgcccgagccctcctgcccagag
ctggccacactcaccagccagtgtctgacctatgagccaacccagaggccttcattccgc
accatcctgcgtgacctcacccggctgcagccccacactcttccagatcttgctgacgtc
ttgattgtgaacccggactcatcggcgtcagaccctacggttttccacaagcgctatttg
aaaaagatccgagatctgggcgagggtcacttcggcaaggtcagtttgtactgctacgat
ccgaccaacgacggcactggcgagatggtggcggtgaaagcccttaaggcagactgcggc
ccccagcaccgcttgggctggaagcaggagattgagattctgcgtacgctctatcacgag
cacatcgtcaagtacaagggctgctgcgaggaccaaggcgagaagtcgctgcagctggtc
atggagtacgtgcccctgggcagcctccgagactacctgccccggcacagcgtggggctg
gcccagctgctgctcttcgcccagcagatctgcgagggcatggcctatctgcacgcgcag
cactacatccaccgagacctagccgcgcgcaacgtgctgctggacaacgacaagctggtc
aagatcggggactttggcctagccaaggccgtgcccgaaggccacgagtactaccgcgtg
cgcgaggatggggacagccctgtgttctggtatgccccagagtgcctgaaggagtgtaag
ttctactatgcgtccgatgtctggtccttcggggtgaccctgtatgagctgctgacgcac
tgtgactccagccagagcccccccacgaaattccttgagctcataggcatcacccagggt
cagatgacagttctgagactcaccgagttgctggaacgaggggagaggctgccacgaccc
gacaaatgtccctgtgaggtctatcatctcatgaagaactgctgggagacagaggcgtcc
ttccgcccaaccttcgagaacctcatacccatcctgaagacagtccatgagaagtaccaa
ggccaggccccttccgtgttcagtgtgtgctga
DBGET
integrated database retrieval system
