Trachypithecus francoisi (Francois's langur): 117085606
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Entry
117085606 CDS
T07225
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn01521
EGFR tyrosine kinase inhibitor resistance
tfn04010
MAPK signaling pathway
tfn04014
Ras signaling pathway
tfn04015
Rap1 signaling pathway
tfn04020
Calcium signaling pathway
tfn04072
Phospholipase D signaling pathway
tfn04144
Endocytosis
tfn04151
PI3K-Akt signaling pathway
tfn04510
Focal adhesion
tfn04540
Gap junction
tfn04630
JAK-STAT signaling pathway
tfn04810
Regulation of actin cytoskeleton
tfn05163
Human cytomegalovirus infection
tfn05200
Pathways in cancer
tfn05206
MicroRNAs in cancer
tfn05214
Glioma
tfn05215
Prostate cancer
tfn05218
Melanoma
tfn05230
Central carbon metabolism in cancer
tfn05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117085606 (PDGFRA)
04014 Ras signaling pathway
117085606 (PDGFRA)
04015 Rap1 signaling pathway
117085606 (PDGFRA)
04630 JAK-STAT signaling pathway
117085606 (PDGFRA)
04020 Calcium signaling pathway
117085606 (PDGFRA)
04072 Phospholipase D signaling pathway
117085606 (PDGFRA)
04151 PI3K-Akt signaling pathway
117085606 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
117085606 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
117085606 (PDGFRA)
04540 Gap junction
117085606 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
117085606 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117085606 (PDGFRA)
05206 MicroRNAs in cancer
117085606 (PDGFRA)
05230 Central carbon metabolism in cancer
117085606 (PDGFRA)
05231 Choline metabolism in cancer
117085606 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
117085606 (PDGFRA)
05218 Melanoma
117085606 (PDGFRA)
05215 Prostate cancer
117085606 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
117085606 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117085606 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117085606 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tfn04090
]
117085606 (PDGFRA)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
117085606 (PDGFRA)
Protein kinases [BR:
tfn01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
117085606 (PDGFRA)
CD molecules [BR:
tfn04090
]
Proteins
117085606 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
117085606
NCBI-ProteinID:
XP_033070546
LinkDB
All DBs
Position
Unknown
AA seq
1089 aa
AA seq
DB search
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGDSEVSWQYP
MSEEENSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYNSRQGFNG
TFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
EMKRVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVQAYPPPRISWLKNNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHPRD
RSTVEGLVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatccggcgttcctggtcttaggctgccttctcacagggctgagccta
atcctctgccagctttcgttaccctctatccttccaaatgaaaatgaaaaggttgtgcag
ctgaattcatccttttctctgagatgctttggggatagtgaagtgagctggcagtacccc
atgtctgaagaagagaactctgatgtggaaatcagaaatgaagaaaacaacagtggcctt
tttgtgacagtcttggaagtgagcagtgcctcggcggcccacacagggttgtacacttgc
tattacaaccacactcagacagaagagaatgagcttgaaggcaggcacatttacatctat
gtgccagacccagatgtagcctttgtacctctaggaatgacggattatttagtcattgtg
gaggacgatgattctgccatcataccttgtcgcacaactgatcccgagactcctgtaact
ttacacaacagcgagggggtggtacctgcctcctacaacagcagacagggctttaatggg
accttcactgtagggccctatatctgtgaggccaccgtcaaaggaaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacatcagagctggatctagaaatggaagct
cttaaaaccgtgtataagtcaggggaaacgattgtggtcacctgtgctgtttttaacaat
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacaatg
ctggaagaaatcaaagtcccatccatcaaattggtgtacactttgacggtccccgaggcc
acggtgaaagacagtggagattacgaatgtgctgcccgccaggctaccagggaggtcaaa
gaaatgaagagagtcactatttctgttcatgagaaagggttcattgaaatcaaacccacc
tttagccagctggaagctgtcaacctgcatgaagtcaaacattttgtcgtagaggtgcag
gcctacccacctcccaggatatcctggctgaaaaacaatctgactctgatcgaaaatctc
acggagatcaccactgatgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
cttatccgtgctaaggaagaagacagtggccattatactattgtagctcaaaatgaagat
gatgtgaagagctatacttttgaactgttaactcaagttccttcatccattctggacttg
gtcgatgatcaccatggctcaactgggggacagacggtgaggtgcacagctgaaggcacg
ccgcttcctgatattgagtggatgatatgcaaggatattaagaaatgtaataatgaaact
tcttggacgattttggccaacaatgtctcaaacatcatcacggagatccacccccgagac
aggagtaccgtggagggccttgtgacttttgccaaagtggaagagaccattgcggtgaga
tgcctggctaagaatctccttggagctgagaaccgagagctgaagctggtggctcccacc
ctgcgttctgaactcacggtggctgctgcagtcctggtgctgctggtgattgtgatcatc
tcactcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatcaatcagcccagatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggactagtgcttggtcgggtcttgggg
tctggagcatttgggaaggtggttgaaggaacagcctatggattaagccggtcccaacct
gtcatgaaagttgcagtgaagatgctaaaacccacggctagatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgactcacctggggccacatttgaacattgtaaacttg
ctgggagcctgcaccaaatcaggccccatttacatcatcacagagtactgcttctacgga
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccagagaag
ccaaagaaagagctggatatctttgggttgaaccctgctgatgacagcacacggagctat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaggctgatactaca
cagtatgtccccatgctagaaaggaaagaggtttctaaatattccgacatccagagatca
ctgtatgatcgtccagcctcatataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatgataactcagaaggccttactttgttggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgggatctggct
gctcgcaacgttctcctggcacaaggaaaaattgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattcgaactacgtatcgaaaggcagtacctttctgcctgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacactgagtgatgtctggtct
tacggcattctgctctgggagatcttttcccttggtggtactccttaccccggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gctaccagtgaagtctatgagatcatggtgaaatgctggaacagtgagccagagaagaga
ccctctttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaaaattcatctggacttcctgaagagtgaccatcctgctgtggcacgcatg
cgtgtggactcagacaatgcgtacattggtgtcacctacaaaaatgaggaagacaagctg
aaggactgggagggtggtctggatgagcagagactgagcgctgacagcggctacatcatt
cctctgcctgacattgaccctgtccctgaggaggaggacctgggcaagaggaacagacac
agctcgcagacctctgaagagagtgccattgagacgggttccagcagttccaccttcatc
aagagagaggacgagaccattgaagacatcgacatgatggacgacatcggcatagactct
tcagacctggtggaagacagcttcctgtaa
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integrated database retrieval system
