KEGG   Trachypithecus francoisi (Francois's langur): 117096627
Entry
117096627         CDS       T07225                                 
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
tfn  Trachypithecus francoisi (Francois's langur)
Pathway
tfn01521  EGFR tyrosine kinase inhibitor resistance
tfn01522  Endocrine resistance
tfn01524  Platinum drug resistance
tfn04010  MAPK signaling pathway
tfn04012  ErbB signaling pathway
tfn04014  Ras signaling pathway
tfn04015  Rap1 signaling pathway
tfn04022  cGMP-PKG signaling pathway
tfn04024  cAMP signaling pathway
tfn04062  Chemokine signaling pathway
tfn04066  HIF-1 signaling pathway
tfn04068  FoxO signaling pathway
tfn04071  Sphingolipid signaling pathway
tfn04072  Phospholipase D signaling pathway
tfn04114  Oocyte meiosis
tfn04140  Autophagy - animal
tfn04148  Efferocytosis
tfn04150  mTOR signaling pathway
tfn04151  PI3K-Akt signaling pathway
tfn04210  Apoptosis
tfn04218  Cellular senescence
tfn04261  Adrenergic signaling in cardiomyocytes
tfn04270  Vascular smooth muscle contraction
tfn04350  TGF-beta signaling pathway
tfn04360  Axon guidance
tfn04370  VEGF signaling pathway
tfn04371  Apelin signaling pathway
tfn04380  Osteoclast differentiation
tfn04510  Focal adhesion
tfn04517  IgSF CAM signaling
tfn04520  Adherens junction
tfn04540  Gap junction
tfn04550  Signaling pathways regulating pluripotency of stem cells
tfn04611  Platelet activation
tfn04613  Neutrophil extracellular trap formation
tfn04620  Toll-like receptor signaling pathway
tfn04621  NOD-like receptor signaling pathway
tfn04625  C-type lectin receptor signaling pathway
tfn04650  Natural killer cell mediated cytotoxicity
tfn04657  IL-17 signaling pathway
tfn04658  Th1 and Th2 cell differentiation
tfn04659  Th17 cell differentiation
tfn04660  T cell receptor signaling pathway
tfn04662  B cell receptor signaling pathway
tfn04664  Fc epsilon RI signaling pathway
tfn04666  Fc gamma R-mediated phagocytosis
tfn04668  TNF signaling pathway
tfn04713  Circadian entrainment
tfn04720  Long-term potentiation
tfn04722  Neurotrophin signaling pathway
tfn04723  Retrograde endocannabinoid signaling
tfn04724  Glutamatergic synapse
tfn04725  Cholinergic synapse
tfn04726  Serotonergic synapse
tfn04730  Long-term depression
tfn04810  Regulation of actin cytoskeleton
tfn04910  Insulin signaling pathway
tfn04912  GnRH signaling pathway
tfn04914  Progesterone-mediated oocyte maturation
tfn04915  Estrogen signaling pathway
tfn04916  Melanogenesis
tfn04917  Prolactin signaling pathway
tfn04919  Thyroid hormone signaling pathway
tfn04921  Oxytocin signaling pathway
tfn04926  Relaxin signaling pathway
tfn04928  Parathyroid hormone synthesis, secretion and action
tfn04929  GnRH secretion
tfn04930  Type II diabetes mellitus
tfn04933  AGE-RAGE signaling pathway in diabetic complications
tfn04934  Cushing syndrome
tfn04935  Growth hormone synthesis, secretion and action
tfn04960  Aldosterone-regulated sodium reabsorption
tfn05010  Alzheimer disease
tfn05020  Prion disease
tfn05022  Pathways of neurodegeneration - multiple diseases
tfn05034  Alcoholism
tfn05132  Salmonella infection
tfn05133  Pertussis
tfn05135  Yersinia infection
tfn05140  Leishmaniasis
tfn05142  Chagas disease
tfn05145  Toxoplasmosis
tfn05152  Tuberculosis
tfn05160  Hepatitis C
tfn05161  Hepatitis B
tfn05163  Human cytomegalovirus infection
tfn05164  Influenza A
tfn05165  Human papillomavirus infection
tfn05166  Human T-cell leukemia virus 1 infection
tfn05167  Kaposi sarcoma-associated herpesvirus infection
tfn05170  Human immunodeficiency virus 1 infection
tfn05171  Coronavirus disease - COVID-19
tfn05200  Pathways in cancer
tfn05203  Viral carcinogenesis
tfn05205  Proteoglycans in cancer
tfn05206  MicroRNAs in cancer
tfn05207  Chemical carcinogenesis - receptor activation
tfn05208  Chemical carcinogenesis - reactive oxygen species
tfn05210  Colorectal cancer
tfn05211  Renal cell carcinoma
tfn05212  Pancreatic cancer
tfn05213  Endometrial cancer
tfn05214  Glioma
tfn05215  Prostate cancer
tfn05216  Thyroid cancer
tfn05218  Melanoma
tfn05219  Bladder cancer
tfn05220  Chronic myeloid leukemia
tfn05221  Acute myeloid leukemia
tfn05223  Non-small cell lung cancer
tfn05224  Breast cancer
tfn05225  Hepatocellular carcinoma
tfn05226  Gastric cancer
tfn05230  Central carbon metabolism in cancer
tfn05231  Choline metabolism in cancer
tfn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tfn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117096627 (MAPK1)
   04012 ErbB signaling pathway
    117096627 (MAPK1)
   04014 Ras signaling pathway
    117096627 (MAPK1)
   04015 Rap1 signaling pathway
    117096627 (MAPK1)
   04350 TGF-beta signaling pathway
    117096627 (MAPK1)
   04370 VEGF signaling pathway
    117096627 (MAPK1)
   04371 Apelin signaling pathway
    117096627 (MAPK1)
   04668 TNF signaling pathway
    117096627 (MAPK1)
   04066 HIF-1 signaling pathway
    117096627 (MAPK1)
   04068 FoxO signaling pathway
    117096627 (MAPK1)
   04072 Phospholipase D signaling pathway
    117096627 (MAPK1)
   04071 Sphingolipid signaling pathway
    117096627 (MAPK1)
   04024 cAMP signaling pathway
    117096627 (MAPK1)
   04022 cGMP-PKG signaling pathway
    117096627 (MAPK1)
   04151 PI3K-Akt signaling pathway
    117096627 (MAPK1)
   04150 mTOR signaling pathway
    117096627 (MAPK1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    117096627 (MAPK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    117096627 (MAPK1)
   04148 Efferocytosis
    117096627 (MAPK1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    117096627 (MAPK1)
   04210 Apoptosis
    117096627 (MAPK1)
   04218 Cellular senescence
    117096627 (MAPK1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    117096627 (MAPK1)
   04520 Adherens junction
    117096627 (MAPK1)
   04540 Gap junction
    117096627 (MAPK1)
   04550 Signaling pathways regulating pluripotency of stem cells
    117096627 (MAPK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    117096627 (MAPK1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    117096627 (MAPK1)
   04613 Neutrophil extracellular trap formation
    117096627 (MAPK1)
   04620 Toll-like receptor signaling pathway
    117096627 (MAPK1)
   04621 NOD-like receptor signaling pathway
    117096627 (MAPK1)
   04625 C-type lectin receptor signaling pathway
    117096627 (MAPK1)
   04650 Natural killer cell mediated cytotoxicity
    117096627 (MAPK1)
   04660 T cell receptor signaling pathway
    117096627 (MAPK1)
   04658 Th1 and Th2 cell differentiation
    117096627 (MAPK1)
   04659 Th17 cell differentiation
    117096627 (MAPK1)
   04657 IL-17 signaling pathway
    117096627 (MAPK1)
   04662 B cell receptor signaling pathway
    117096627 (MAPK1)
   04664 Fc epsilon RI signaling pathway
    117096627 (MAPK1)
   04666 Fc gamma R-mediated phagocytosis
    117096627 (MAPK1)
   04062 Chemokine signaling pathway
    117096627 (MAPK1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    117096627 (MAPK1)
   04929 GnRH secretion
    117096627 (MAPK1)
   04912 GnRH signaling pathway
    117096627 (MAPK1)
   04915 Estrogen signaling pathway
    117096627 (MAPK1)
   04914 Progesterone-mediated oocyte maturation
    117096627 (MAPK1)
   04917 Prolactin signaling pathway
    117096627 (MAPK1)
   04921 Oxytocin signaling pathway
    117096627 (MAPK1)
   04926 Relaxin signaling pathway
    117096627 (MAPK1)
   04935 Growth hormone synthesis, secretion and action
    117096627 (MAPK1)
   04919 Thyroid hormone signaling pathway
    117096627 (MAPK1)
   04928 Parathyroid hormone synthesis, secretion and action
    117096627 (MAPK1)
   04916 Melanogenesis
    117096627 (MAPK1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117096627 (MAPK1)
   04270 Vascular smooth muscle contraction
    117096627 (MAPK1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    117096627 (MAPK1)
  09156 Nervous system
   04724 Glutamatergic synapse
    117096627 (MAPK1)
   04725 Cholinergic synapse
    117096627 (MAPK1)
   04726 Serotonergic synapse
    117096627 (MAPK1)
   04720 Long-term potentiation
    117096627 (MAPK1)
   04730 Long-term depression
    117096627 (MAPK1)
   04723 Retrograde endocannabinoid signaling
    117096627 (MAPK1)
   04722 Neurotrophin signaling pathway
    117096627 (MAPK1)
  09158 Development and regeneration
   04360 Axon guidance
    117096627 (MAPK1)
   04380 Osteoclast differentiation
    117096627 (MAPK1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    117096627 (MAPK1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    117096627 (MAPK1)
   05206 MicroRNAs in cancer
    117096627 (MAPK1)
   05205 Proteoglycans in cancer
    117096627 (MAPK1)
   05207 Chemical carcinogenesis - receptor activation
    117096627 (MAPK1)
   05208 Chemical carcinogenesis - reactive oxygen species
    117096627 (MAPK1)
   05203 Viral carcinogenesis
    117096627 (MAPK1)
   05230 Central carbon metabolism in cancer
    117096627 (MAPK1)
   05231 Choline metabolism in cancer
    117096627 (MAPK1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    117096627 (MAPK1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    117096627 (MAPK1)
   05212 Pancreatic cancer
    117096627 (MAPK1)
   05225 Hepatocellular carcinoma
    117096627 (MAPK1)
   05226 Gastric cancer
    117096627 (MAPK1)
   05214 Glioma
    117096627 (MAPK1)
   05216 Thyroid cancer
    117096627 (MAPK1)
   05221 Acute myeloid leukemia
    117096627 (MAPK1)
   05220 Chronic myeloid leukemia
    117096627 (MAPK1)
   05218 Melanoma
    117096627 (MAPK1)
   05211 Renal cell carcinoma
    117096627 (MAPK1)
   05219 Bladder cancer
    117096627 (MAPK1)
   05215 Prostate cancer
    117096627 (MAPK1)
   05213 Endometrial cancer
    117096627 (MAPK1)
   05224 Breast cancer
    117096627 (MAPK1)
   05223 Non-small cell lung cancer
    117096627 (MAPK1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117096627 (MAPK1)
   05170 Human immunodeficiency virus 1 infection
    117096627 (MAPK1)
   05161 Hepatitis B
    117096627 (MAPK1)
   05160 Hepatitis C
    117096627 (MAPK1)
   05171 Coronavirus disease - COVID-19
    117096627 (MAPK1)
   05164 Influenza A
    117096627 (MAPK1)
   05163 Human cytomegalovirus infection
    117096627 (MAPK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    117096627 (MAPK1)
   05165 Human papillomavirus infection
    117096627 (MAPK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    117096627 (MAPK1)
   05135 Yersinia infection
    117096627 (MAPK1)
   05133 Pertussis
    117096627 (MAPK1)
   05152 Tuberculosis
    117096627 (MAPK1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    117096627 (MAPK1)
   05140 Leishmaniasis
    117096627 (MAPK1)
   05142 Chagas disease
    117096627 (MAPK1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117096627 (MAPK1)
   05020 Prion disease
    117096627 (MAPK1)
   05022 Pathways of neurodegeneration - multiple diseases
    117096627 (MAPK1)
  09165 Substance dependence
   05034 Alcoholism
    117096627 (MAPK1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117096627 (MAPK1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    117096627 (MAPK1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    117096627 (MAPK1)
   04934 Cushing syndrome
    117096627 (MAPK1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    117096627 (MAPK1)
   01524 Platinum drug resistance
    117096627 (MAPK1)
   01522 Endocrine resistance
    117096627 (MAPK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tfn01001]
    117096627 (MAPK1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:tfn03036]
    117096627 (MAPK1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tfn04147]
    117096627 (MAPK1)
Enzymes [BR:tfn01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     117096627 (MAPK1)
Protein kinases [BR:tfn01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   117096627 (MAPK1)
Chromosome and associated proteins [BR:tfn03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     117096627 (MAPK1)
Exosome [BR:tfn04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   117096627 (MAPK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH STATB_N Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 117096627
NCBI-ProteinID: XP_033089972
LinkDB
Position
Unknown
AA seq 360 aa
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq 1083 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtgggaccgcgctacaccaatctctcgtacatcggcgagggtgcctacggcatggtgtgc
tctgcttatgataatgtcaacaaagttcgagtagctatcaagaaaatcagcccctttgag
caccagacctactgccagagaaccctgcgggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgacattattcgagcaccaaccattgagcaaatgaaagat
gtatatatagtacaagacctcatggaaacagatctttacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaacgttctgcaccgtgacctcaagccttccaacctgctgctcaacaccacc
tgtgatctcaagatctgtgactttggcctggcccgtgttgcagatccagaccatgatcac
acagggttcctgacagaatatgtggccacacgttggtacagggctccagaaattatgttg
aattccaagggctacaccaagtccattgatatttggtctgtaggctgcattctggcagaa
atgctttctaacaggcccatctttccagggaagcattatcttgaccagctgaaccacatt
ctgggtattcttggatccccatcacaagaagacctgaattgtataataaatttaaaagct
aggaactatttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggacttactggacaaaatgttgacattcaaccctcacaag
aggattgaagtagaacaggctctggcccacccatatctggagcagtattacgacccgagt
gacgagcccattgctgaagcaccattcaagttcgacatggaattggatgacttgcctaag
gaaaagctcaaagaactaatttttgaagagactgctagattccagccaggatacagatct
taa

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