Trachypithecus francoisi (Francois's langur): 117098543
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Entry
117098543 CDS
T07225
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
tfn
Trachypithecus francoisi (Francois's langur)
Pathway
tfn01521
EGFR tyrosine kinase inhibitor resistance
tfn04062
Chemokine signaling pathway
tfn04081
Hormone signaling
tfn04148
Efferocytosis
tfn04151
PI3K-Akt signaling pathway
tfn04217
Necroptosis
tfn04550
Signaling pathways regulating pluripotency of stem cells
tfn04630
JAK-STAT signaling pathway
tfn04658
Th1 and Th2 cell differentiation
tfn04659
Th17 cell differentiation
tfn04725
Cholinergic synapse
tfn04917
Prolactin signaling pathway
tfn04920
Adipocytokine signaling pathway
tfn04933
AGE-RAGE signaling pathway in diabetic complications
tfn04935
Growth hormone synthesis, secretion and action
tfn05140
Leishmaniasis
tfn05145
Toxoplasmosis
tfn05152
Tuberculosis
tfn05161
Hepatitis B
tfn05164
Influenza A
tfn05167
Kaposi sarcoma-associated herpesvirus infection
tfn05168
Herpes simplex virus 1 infection
tfn05200
Pathways in cancer
tfn05207
Chemical carcinogenesis - receptor activation
tfn05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
tfn05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tfn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
117098543 (JAK2)
04151 PI3K-Akt signaling pathway
117098543 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
117098543 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
117098543 (JAK2)
09143 Cell growth and death
04217 Necroptosis
117098543 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
117098543 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
117098543 (JAK2)
04659 Th17 cell differentiation
117098543 (JAK2)
04062 Chemokine signaling pathway
117098543 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
117098543 (JAK2)
04917 Prolactin signaling pathway
117098543 (JAK2)
04935 Growth hormone synthesis, secretion and action
117098543 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
117098543 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
117098543 (JAK2)
05207 Chemical carcinogenesis - receptor activation
117098543 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
117098543 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
117098543 (JAK2)
05164 Influenza A
117098543 (JAK2)
05168 Herpes simplex virus 1 infection
117098543 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
117098543 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
117098543 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117098543 (JAK2)
05140 Leishmaniasis
117098543 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117098543 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
117098543 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
117098543 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfn01001
]
117098543 (JAK2)
Enzymes [BR:
tfn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
117098543 (JAK2)
Protein kinases [BR:
tfn01001
]
Non-receptor tyrosine kinases
JAK family [OT]
117098543 (JAK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
117098543
NCBI-ProteinID:
XP_033093142
LinkDB
All DBs
Position
Unknown
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEGTSTSSIYQNGDISGNANSMKQIDPVLQVYLYHSLGKSEADYLTFPSGEY
VAEEICIAASKACGITPVYHNMFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPR
WYCSGSNRAYRHGISRGAEAPLLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMA
VLDMMRIAKENDQTPLAIYNSISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARNLKLKYLINLETLQSAFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGK
HKESETLTEQDLQLYCDFPNIIDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQ
KETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGIRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
KLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMH
FLEENTLIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYMIMTECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcctgccttactatgacagaaatggagggaacatccacatcttctatatatcagaat
ggtgatatttctggaaatgccaattctatgaagcaaatagatccagtccttcaggtgtat
ctttaccattcccttgggaaatctgaggcagattatctgacctttccatctggggagtat
gttgcagaagaaatctgtattgctgcttctaaagcttgtggtatcacacctgtgtatcat
aatatgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccatgtcttc
catatagatgagtcaaccaggcataatgtactctacagaataagattttactttcctcgt
tggtattgcagcggcagcaacagagcctatcggcatggaatatctcgaggtgctgaagct
cctcttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgattttgtg
catggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggca
gtgttagatatgatgagaatagccaaagaaaatgatcaaaccccactggccatctataac
tctatcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagactatcat
attttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttcagccaa
tgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaccctgcag
tctgccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaa
cataaagaaagtgagacactgacagaacaggatttacagttatattgcgattttcctaat
attattgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccgagttgta
actatccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagct
ttgtctttcgtgtcattaattgatgggtattatagattaactgcagatgcacatcattac
ctctgtaaagaagtagcacctccaacagtgcttgaaaatatacaaagcaactgtcatggc
ccaatttcgatggattttgccattagtaaactgaagaaagcaggtaatcagactggactg
tatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgccgtcgag
cgagaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaagagtac
aacctcagtgggacaaagaagaacttcagcagtcttaaagatcttttgaattgttaccag
aaggaaaccgttcgctcagacaatataattttccagtttactaagtgctgtcccccaaag
ccaaaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgtaccaacc
tcaccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatcagaaat
gaagatttgatatttaatgaaagccttggccaaggcacttttacaaagatttttaaaggc
atacgaagagaagtaggagactatggtcaactgcatgaaacagaagttcttttaaaagtt
ctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagc
aagctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagaggagaat
attctggttcaggagtttgtaaaatttggatcactagatacatacctgaaaaagaataaa
aattgtataaatatattgtggaaacttgaagttgcaaaacagttggcatgggccatgcat
tttctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattctacttatc
agagaagaagacaggaagacaggaaatcctcctttcatcaaactcagtgatcctggcatt
agtattacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaa
tgcattgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggtaccact
ttgtgggaaatctgcagtggaggagataaacctctaagtgctctggattctcaaagaaag
ctgcaattttatgaagataggcaccagcttcctgcaccaaagtgggcagaattagcaaac
cttataaataattgtatggattatgagccagatttcaggccttctttcagagctatcata
cgagatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgtta
ccaaatatgaggataggtgccctagggttttctggtgcctttgaagacagggatcctaca
cagtttgaagagagacatttgaaatttctccagcaactcggcaagggtaattttgggagt
gtggagatgtgccggtatgaccctctacaggacaacactggggaggtggtggctgtaaaa
aagcttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaaatcctg
aaatccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggtcgg
cgtaatctaaaattaattatggaatatttaccatatggaagtttacgagactatcttcaa
aaacataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatatgcaag
ggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagaaatata
ttggtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttgcca
caagacaaagaatactataaagtaaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtg
gttctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaatttatg
cgtatgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaacttttg
aagaataatggaagattaccaagaccagatggatgcccagatgagatttatatgatcatg
acagaatgctggaacaataatgtaaatctgcgcccctcctttagagatttagctcttcga
gtggatcaaataagggataacatggctggatga
DBGET
integrated database retrieval system
