Takifugu flavidus (sansaifugu): 130514396
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Entry
130514396 CDS
T09160
Symbol
tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
tfs
Takifugu flavidus (sansaifugu)
Pathway
tfs04217
Necroptosis
tfs04620
Toll-like receptor signaling pathway
tfs04621
NOD-like receptor signaling pathway
tfs05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
tfs00001
]
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
130514396 (tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
130514396 (tyk2)
04621 NOD-like receptor signaling pathway
130514396 (tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
130514396 (tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tfs01001
]
130514396 (tyk2)
Enzymes [BR:
tfs01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
130514396 (tyk2)
Protein kinases [BR:
tfs01001
]
Non-receptor tyrosine kinases
JAK family [OT]
130514396 (tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
SH2_1
Kinase-like
Kdo
RIO1
FERM_C_FAK1
ABC1
Motif
Other DBs
NCBI-GeneID:
130514396
NCBI-ProteinID:
XP_056869917
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Position
18:9294071..9301462
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AA seq
1135 aa
AA seq
DB search
MSRSSSKRSKGDLFPGTVQPPRCKGIHVYLFCTKEGGTYLSHTSGDVTAEELCFLAAKAV
GITPLCHVLFALYNPLATCWYSPSHTFTTEVHSTLVLHYCMRYYFRNWHGLNENEPTVSR
YPLKSKTEKELLSLFDVRSLDYLFSQAKYEFVNKIVHMEDMKTEEEISSFKNESLGMAVL
HMSHQALQTGSTLQEVAKKHSYLDCIPKCFAKHISKDNFLTKIRIRRVFADFVQTFQEHT
VENGRLDTQKIMYKYISTLERLEPNFGIEIFHVSHLNLRETWEESGSLPNKTHPQCDCKA
PATHEIMVNGNKGISWRISTQKAQSPQPDTPNDWTAFCDFPEIAHIAITETNVCISTQDN
HCMEVQMSSTQEAHSFISLLDGYYRLTADAHNYLCHDLAPPRVLLNEANGLHGPMHGCFA
LQKLKKEAAEEGAYLICWSAVNYENLVLIVHNKNKNGSAQNHKQFQIKLKGSKFCLDGWD
LQYSSVRELMDSLKNFVLMSGSESFTVKKCCLPRHGELSNLLVMRTPFQPSSKTSRVQVP
YIPDKDLVQGQHLGSGTITNIYRGLLLVHGGGDNGEEDKFNNNASSQTEIPVVLKILNPN
HDELSLTFIESVGTMSQVSHRHLVHVHGLSVKEHQHIMVEDFVKFGPLDVFLHKEKASIS
DRWKFIVAIQLASALSYLENKQLIHGNVCARNILLARCGLDTGTAPFIKLSDPGIPISAL
EREERLERIPWIAPECIDGGESNQSATDQWSFGATFLEICYNGTLPISTSSEKERFYQQK
GRLPVLSSQEVSNFINTCLAYDPMDRPSFCIVLRELSEFMNKNLDISPSETLPDTGQGVF
NKRFLKEIEDLGEGNFGKVTLCLYDPANDGSGEHVAVKALKQENGNIAGWIKEIDVLKSL
DHCNIVKYKGCCSERGGQGLQLIMEFLPQGSLAKYLPKHKPHQSQLLIFAQQICQGMDYL
HSKRYVHRDLAARNILLDRNTQVKIGDFGLTKCIPEGASYYRVSENEDSPVYWFAVECLK
DNKFSFASDVWAFGVTLYEIFSYCNSKQSPPKKFNEMLEKSSKMSQMLLISLLEKQKRLP
CPKNCPLEVRMIMERCWATEPQQRPAFISLIEKFGDMCRKHEGNSCRNSSLAQVC
NT seq
3408 nt
NT seq
+upstream
nt +downstream
nt
atgtctcgaagttcctccaagcgttcaaagggagacctatttccgggtacggtccaacct
cctcggtgcaaaggtatccatgtttacctcttctgtacaaaagaagggggcacatatttg
tcccacaccagcggagacgtgacagcagaggagctttgcttcttggctgccaaggctgta
ggcatcactcccctgtgccatgttttgtttgctctgtacaatccactggcaacctgctgg
tacagtcccagtcacaccttcaccacagaagttcactccactcttgtactccactactgt
atgagatattattttcggaattggcatggacttaatgaaaatgagccaactgtatcccgg
tatcctctcaaatcaaagacggaaaaagagctcttgtctttatttgatgtcagatccttg
gactatctgttctcccaggctaaatatgaatttgtcaacaaaatagttcacatggaagac
atgaaaacggaggaggaaattagcagcttcaaaaatgagagcctggggatggctgtcctt
cacatgtcacaccaggcattacaaacaggcagcacactacaggaagttgctaaaaaacac
agctacttagactgcatcccaaagtgtttcgccaaacatatttccaaagacaacttcctt
acaaaaataaggattcggcgggtgtttgcagattttgtgcagacatttcaggagcacact
gtggaaaatgggcgactggatacccaaaagatcatgtataagtacatctctacccttgaa
cgtttggagccgaatttcggcatagagatcttccacgtatcccatctgaacttaagagaa
acctgggaagaaagtggctctttgcccaacaaaacgcatccacagtgtgactgtaaagca
cctgcgacgcatgaaataatggtgaatggcaacaaagggatctcgtggcgaatatccact
caaaaggcacagtcgccacaacctgacacacccaatgattggactgccttctgtgatttc
ccagaaattgcacacatagccattactgagactaatgtgtgcattagcactcaggacaat
cactgcatggaggttcaaatgagctcaacccaagaggcccattccttcatctccctccta
gatggatactaccggctgactgcagacgcccacaactatctttgtcatgatctggctccc
ccaagggtactgctgaatgaagcaaatggactgcacggacctatgcatggttgttttgcg
cttcaaaagctgaaaaaggaggcagctgaggagggggcttacctcatatgttggagtgct
gtaaattatgaaaaccttgtcctgattgtccataacaaaaataagaatggctcagcacaa
aaccacaagcagtttcagattaagctcaagggttcgaagttctgtctggatggttgggac
ctacagtactccagtgtgagggagctcatggacagtctcaagaactttgtgctcatgtct
ggttcagaaagcttcactgtcaagaaatgctgtttgccacggcatggagagctatccaat
cttttggtgatgaggactccctttcaaccttcctcaaagacatcccgggtacaagtaccc
tacatcccagacaaagatcttgtgcagggacaacatttgggcagtgggacgattacaaac
atatatagaggattgttgcttgttcacgggggaggagacaatggtgaggaggataaattc
aacaacaacgccagtagccaaacagagatcccggtggttcttaagatcctaaatccaaac
catgatgaactgtcactcacctttattgaaagtgtaggtaccatgagccaggtatcccac
aggcacttggtgcatgtacatggtctgtcagtcaaagaacatcaacatatcatggtggaa
gattttgtgaaatttggtcctcttgatgttttccttcataaagaaaaggcctcaatctct
gatcgctggaaattcatcgttgcaatacaacttgccagtgctttgagttaccttgagaac
aaacagctgattcatggaaatgtatgtgcaaggaacattttgttggcacgttgtggccta
gatacaggtactgcacctttcatcaagctgagtgacccaggaatccccatcagtgccctt
gaacgggaagaacgtctggagcgtatcccatggattgccccagagtgtattgacggtggt
gaatccaaccaaagtgccactgatcagtggagttttggagcaacattccttgaaatatgc
tataacggaactctgcccatcagcacatcatctgagaaagagcgcttttaccagcaaaaa
ggacgcctgcctgtcctctcctcccaggaggtgtccaacttcatcaacacctgcttggct
tacgaccccatggacaggccttctttttgcattgtgctcagagaactctcagagttcatg
aacaaaaatcttgatatatcaccaagtgaaacgctccccgacacgggtcagggtgtattc
aataaacgctttctgaaagagattgaagacttaggagagggtaactttggaaaggtgact
ctctgcttgtatgacccagccaatgatggttctggagagcatgtggcagtaaaagctttg
aagcaagaaaatggtaacattgcgggctggataaaggaaatagacgttctgaagtcactc
gatcattgcaacattgtgaagtacaagggatgttgtagtgaaagaggtggacaagggctg
cagctaatcatggagttccttccacaagggagcctggcaaagtaccttcccaagcacaag
cctcaccagtcccagttgctgatatttgctcagcagatctgtcagggtatggattatctg
cattccaagcgatatgtccatcgagaccttgctgcccgaaatatattgttggacagaaac
actcaagtcaagattggagattttggtctcacgaaatgcatccctgaaggagcatcgtat
taccgtgtctctgagaatgaggacagtcctgtgtactggtttgcagttgagtgtttgaag
gataacaaattttccttcgcctctgatgtttgggcctttggagtcacattatatgagatc
ttctcttactgcaactctaaacagagccctccaaagaaatttaatgaaatgttggaaaaa
tcttcaaaaatgagtcaaatgcttctcattagtctgttggagaagcaaaagcgactgcct
tgtcccaaaaactgcccgctggaggtgaggatgataatggagcgatgttgggctactgag
ccgcaacagcgaccagcattcatttccctgattgaaaagtttggagacatgtgccgaaag
catgaggggaattcctgcagaaactcttctttagctcaggtctgctaa
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