Takifugu flavidus (sansaifugu): 130527849 Help Entry 130527849         CDS       T09160                                  Symbol pkd1a Name (RefSeq) polycystin-1 isoform X1   KO K04985   polycystin 1 Organism tfs  Takifugu flavidus (sansaifugu) Brite KEGG Orthology (KO) [BR:tfs00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:tfs03037]     130527849 (pkd1a)    04812 Cytoskeleton proteins [BR:tfs04812]     130527849 (pkd1a)    04040 Ion channels [BR:tfs04040]     130527849 (pkd1a)    04091 Lectins [BR:tfs04091]     130527849 (pkd1a) Cilium and associated proteins [BR:tfs03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    130527849 (pkd1a) Cytoskeleton proteins [BR:tfs04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     130527849 (pkd1a) Ion channels [BR:tfs04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    130527849 (pkd1a) Lectins [BR:tfs04091]  C-Type lectins   Others    130527849 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT PKD_channel Polycystin_dom Lectin_C LRR_8 LRR_4 WSC GPS Ion_trans Motif Other DBs NCBI-GeneID:  130527849 NCBI-ProteinID:  XP_056892606 LinkDB All DBs Position 6:12475937..12514032 Genome browser AA seq 4627 aa AA seqDB search MPCGNGQTLSKRKHGVCVPRLSFCSFLFVALWCLEARGSGPPGDGGRSCSPCPANCSCVL ATGPQHSCVVNCTNIGLERAPAAADIPLATSVLDLSKNHISSFDISLLERVVGLRELYLH GNRINVLPRGVFCCGPLSTIDLSNNQISTIEEGTCNRQCNLTQIDLSGNPFECHCKLFRL VSWLREKGVKVRRPEATLCDNPPALRHRPLLNVSLLTCDLNYVACLKESSSGGGAERSEL VIFSSSTPGNFTREQCNSVCFTASHRYGGLGGRHECLCSTNSEPNFISESQCSAACTNPQ VMEECRWTLAHDVFEVNFSISLRPLPIQNVHSSISFSAASSVAPVTMSWDFGDLSSRVNT SGAGGTTTTSHKYGHPGRYLVSLMGWSGNNKVSAHGEVMVTLPPKLELHCPTLVVANQSL QLTLVSWGSVDVDVDWKITKHGVQVAKASPHCPKDGVLHEESSRCFQIVPGELSWTDARK QCLDRGGDLAIVRNDALRNLLARKVTQAYGSSMERGVWLGLSDVNSAGKLHWVNGSEAQE GEEGLAPWSSVARGNLCVSLDQRSQTSSHSCNARRAYVCQYNPQVRVPDSGVFAMGLAVF PSHHLLQATAAMIATPPPPHGGVEVLLFPALSFVRAGRLSSLEFVTRELSSQTHILFQIY RPRCRYPGLHLLLPSCGGPACSPMALCVPSESRSADPPSCPRLEQWCPFQHRCLPLSSPC QPSSCLNCSQGHQLPSEARMPLYTLQYEVLFSLTAGPAAHVLLQDQLEDLLVSRGDVIAL QHDAGPASLIHCQSSPHSLWRQPVFALNLSEWFGINNTPVPPDNLAGDGADPLPDPELDL KALVDGTRGSWLENAVCPIRVLYVGQSETRLRGAELSAGLPQPGLYNLLVTSAKQSDLVS ASCSLQVLPPLDLTVLHPSPQNGTLFLESNRTRLLLRVQSRYETKAFYRTSNSSATFHPY CPQEFSSRLCHPSTSEGSGAEVAEPSMYAVLDLNLKIKEHTGPVQVELMAHNNVTEASLT VLVQLEESLRGLVVQPHPARRVLMESVVSYTASVLEGSNPTFKWTVDDKPFFTYYNTVLN VIYQHADVYKLTVTAMNHVSTLTEDFNVTVDRLQPMTNLTVKGVPDVVPQGSTQTLTTSV LIDMAVPATVRWSFGDGGYEQFEHKPPYPSSLTCPESPYQVLLSSNVTYIYSQPGIYTAV VSVSNRYENISRSINMSVYSILTRVDIQTEPSLLLAGKTADFEAHPLPSPYGIHYEWNFG DGSALLQGRRVAHTFEKSGPFNVCVSVNNTISSTAVCTEMFAYEEIESLTAESSSPTELH SATTVRAHLSSGNNITWTFSMGDGKSYTLSEPTVSHKYAKDGRFTVNITAMNAVSSGWMI IPVEVFVFQVAGIEPSGCVGEHALVNFRARVSGNASAYLYEWSFGDGSPNETHHGNPGIS HTYRGNGTHPLSLTITSGVSKANFVTQVCVQPVLTKISVTAEKSHFAVGEKIQFQARAEP EFNYTYEWDFGGEEDLVLPHAPANVVKTYNNPGCYVVTVAASNNVSNTTGSVSIEVLTPV GAVVFQHNGTHYNNLTLGVPYYFSAFSSASNVSYLWNFGHGNLLKGQNILHTFNTPGLHN ITLTAANRVGKNHTTVPVAVLASVSGLTINSSLVNVPLNTSVHFEAHMDEGDSVRFSWIL CDHCTPIFRNNTMFYTFRSVGTFNIIVTAENDVGAAQASIYLFVQRELEGLQILVETAEG GGGGVQELDWCYFETNRVVRFHAGFKEGTNLTFTWNVILKHEPDRSIFNLTGKTAKVNPS KPGPCDIFLQAANLLGQVTVNRTIYFLEPARNVQLQISDNPVAVNALINMTVLNTEGSNL QYRWFVNGDDLQWSKSWMSHTFTSAGQKQVTVKVFNEVSSEVQSEIVSVQEVISGLKITS ADATEQNYFPTDVSVCLQGEVSTGTNVTWSWLIDGMSKMQKKACVAFPKPKTVAVTLNAT NDVSGKVVSREFFVQERIFSLELKASKKIAAINEKVEFSISLVAGTNVNLSLSISRDATV VLQPNQTYVHTFSRVDTYMVNLTAYNEVSCKRRNLHIEVMEPVRGLSIQDSCAAIAVGEK KVFVANVQTGKPVHFLWTFDLHHLHKETHMGKEFRANPSFGAGTMVFYTAEEEGLLTIYL GAINALHAQNITRQMLAQNVLMDAVLYALPQDTFVNKMVTMNVLVTPKSNFMDCLWIFGD VSAPRHTNNTTVGHEYTHPGHYRVQVNCSNLVSWVSAHAEINVSVLECEEPEVQVVQAPR LAIWRSQPTLVEASVDLKGCLRYGAQYLWQILSAPSCDNDPHFASGRVNGATRSFPVIPL PAEVDVQRLQLSLPKMVLAAGNYTLVFSLSYENVPLKKAACLQLGVMAARLMPIIEGGTY RVWSRTQDLQLSAEQSYDPNMDPDNQSLLHYHWECQSTSKGPEHCSTLSFGLGSKGPVLG ISGSELEAGIEYTFKLSIGKEGMPPESTTQTVLVQSGHIPMVYLECVSCKAQSLYEVSQN SYVYLRGTCSNCQGFHRGRWSAVTLQNDTLVLDSSSTTTGSGGMNLVLRQGVLHLGESYN FTLHVTDDSLDGEGAASITLHHNMPPDGGECHLRRGGETGQEHGDKEDEVWRIETLLDRV QFSCSGYSDLGVSETPLLYSLLVNRCRDDYCEEFYVYRGSSPEHSAFLPPGFSSAQHRVS VFITVEDHQGAAIRALNKTIKVVLPDPPPEYSSLPHWLSDLIDSKLKKLLDQGDFQRVRE LSLVLITVLNEYEQTRESVRVSRVERGYRGRVRNNITRALTALDLTTVNDIQQTSAALAQ CTAVSREFICEECQNSTLNKLESMLEILQTDTKQGIVTPTEIADNILNIMGDLIHQVSQS TSQSYNQPPYVDSPSPSFIPKDMGGLDPSPPSLEPHPLRVAAKAYSLSSVLMLILMHARV LNEEPLVLKGAEIAATGKLADPQSLLCYHGNNSPDCQLFSIPRAFNNSLGKAAAGRSVMQ LLFQVESNPFPFNYVANYTVSTEVASMEFRTENGTHIPISGLDDSLAITVAVNNGSNGAE TGPEGAGTGGVPTAGAVNISSCDSVIVRVSVGNTNRRAGLFVQLNFTSLQDVGLQDKRED AEELSITAYLHSHEKPNEFNCTDRKRITLGMTRGHDLDHRKYTFFLSPELYDTTLDYFIN VSTACGSGSGAAGVRLEVGVFASLCQYFSESEKQWRTDGMVPLAETNASRAVCRTRHLTA FAAGLFVPANAISFTVPERSGTPSLVVLLVCVLGLMSYVVAAAILHKLDQLDLRRAAVVP LCGCDGLFKYEIQVKTGWSRGAGTTAHVGISLYGRESRSGHRHLDSRGSFARNALDIFHI ATDTSLGNVWKIRIWHDNKGLSPAWMLQYVLVKDLQTGSSSYFLVEEWLSVDNEKTDGHV EIEVEASEEAMLLQLPRLLRYELQRALCESHLWLSLFQRPPRSPFTRLQRATCCALLLQL LLLANTLWYSIVVDVRYSPRPVSRFASLSGETVAVGVVTCLVAYPLYLLVFTLLRMSRSK CVSVEQVPPQVDQESVEIDDFLDNSMGGTSFLFYNGETNSEETNVDLPSPSTRSVESWDM TEGEMEVRDWPDLLSDAPAMGGVGCGAGLPRLKRGQGSRHLGVDMAFNADNEDGANQRHK HFTSSDEDLIKHILTDGHRFFSQPDESEMADLSSIFEDQTEVILLQKHHEPLPLESVRRD PPRTAFTSNTVVTDVCRPRRFPPSCGRAALWGSWTGIALASGVSMWAGRGFTQNVAMLWL LSCFASFLCSCLLLEPIKVACEAVYYAVYVRRLRPEDQDVLVEFPRVERVVQRVSKVRPP QGFALSQARQQARKVHMLHTMLKNFLVYTFFLLVVLLLNYSDSDKDAHSLRLRTQLQRAL RTPEYRGVSSRGSVLLWLNQSLFPRLLDDSALLRDTGSVLLGTLRLRQIFDKQNDVIPEV GGDGTAENITDYRNISAVNSVPRAWRSGRLKANDSRDVLQLNGSLGEAFSSLQQHHWLDQ RTRAVVVEFSLYNINTNLLAVFSFLIEFPVSDRALSSMDLHVITLWPFTGLDLQLLLTII LLALVLYFLVPGVTGFLREGYTYLLSTWRALGICKLALAASVCGLHLSRCAMATQLWTLY VKHPHDDFTDFYPLARQTQLYTVASALLLFVFVLKVSHQLRFLREWAVFGRALRHSVREL LAVAFALLLLLLAYSHAGHLLLHSVIDGYNSVTSTCLSLVGTSGRTLLSWRASWTTTGPS NTISSLVFHTTFAILRLAFLWLVISVLLRNYQRARAELYRPAVDLQDYEMVELFLRRLKM WMGLSRAKEFRHKVRFEGMELPPSRSSSTGDCKSLCLPPLDAPESPPTPDSIDAGSEASW RPASSSPCSLTEAPGVSLGLGLGLGLNLSPGVMMGNVNWRERAETEASLRRLLPTLDALL QQLDRVTVATEDLYHVECRLERAQSKRRHAGSEKGGAAQGSSGDRVETAGGWRERKRGKE KHGVGKKVEKSELPKDGSASANLKKTPAAASSPFSKPRSAPDSHLPRTNTPTVPPTTPAP TPPPLLAPNAQNWDPPVERDTPPSSSLFNHPAHTTTIPTRKRKRKTPPLKNKVHPNLDKH SPGHPKP NT seq 13884 nt NT seq  +upstreamnt  +downstreamnt atgccttgtggaaatggacagactttatccaagcgaaaacatggcgtctgcgtcccgagg cttagcttctgctcctttctgtttgtggcgctctggtgcctggaggcgcggggctccggg ccgccgggggacggcggcaggagctgcagcccgtgtcccgcgaactgcagctgcgtgctg gcgacggggccccaacactcctgcgtcgtcaactgcaccaacatcggcctggagagggcc ccagcagccgccgacatcccgctggctacttctgtgctagatctttccaagaatcacatc tcctcctttgatatcagccttctggagcgagtcgtgggacttcgtgagctgtatctccat ggaaacaggatcaatgttttacccagaggagttttttgctgtggtccactgtcaacaatc gatttgagcaacaaccagatcagcaccatcgaagaaggaacatgcaaccgtcagtgcaat ttaactcagattgacctcagcggcaaccccttcgagtgtcattgtaaactgttccggctg gtcagctggctgcgggaaaaaggcgtgaaggttcggcgtccggaagccacgctctgcgac aacccgccggcgctccgccaccggccactgctcaacgtcagcctgctcacctgcgatctc aactacgtcgcctgtctgaaggagagcagcagcggcggaggagcggagcggagcgagcta gtcatcttctcttcgtccacgcccggaaacttcacacgcgaacagtgtaacagcgtgtgt tttactgcatcccaccgctacgggggcttgggggggaggcacgagtgcctctgcagcaca aactcggagccgaacttcatcagtgaatcacagtgttctgctgcctgcacaaaccctcag gttatggaggaatgtcgttggactctggcccacgatgtgtttgaggtgaacttttccatc tctctgaggcctcttccaatccaaaatgttcacagcagcattagtttctcagccgcctcc tccgtcgctccggtaaccatgtcctgggactttggagacctgtcctctcgagtgaacacc agcggagccggtgggaccaccacaacctctcacaagtacggacatcctggacgttacctg gtcagtttgatgggatggtctggaaacaacaaggtctctgcacacggagaggtcatggtg acacttccccccaaactggagctgcactgccccacactcgtggtggccaatcagagtctc caactcacacttgttagctggggttctgtcgatgtggatgtggactggaagatcaccaag cacggtgtccaagtcgccaaagcctcccctcactgtccaaaagatggggtgctgcacgaa gagtcctcccgctgtttccagatcgttccaggggagctgagctggaccgatgctcgaaaa cagtgcttggatcgcggcggggatctggcaatagtcaggaatgatgcactgcgtaaccta ctggcacgtaaagtcacacaagcctatgggagctccatggagcgaggcgtgtggctgggg ttaagtgatgtcaactctgctggcaaattacactgggtgaacggctccgaggctcaggaa ggagaggagggcctggcgccttggtcatcggttgcccgtggcaacctttgcgtctcactc gatcagcgcagccagaccagttcgcactcctgcaacgccaggcgggcttacgtctgccag tacaaccctcaagtgcgtgttccggattcaggggtctttgccatgggcctggccgtgttt ccctcccaccatctactccaggccacagctgccatgatcgcaactccgccgccccctcac ggtggcgtagaggtgctcctgtttccagctttgagctttgttcgggcaggtcgtctgtcc tcgctggagtttgtgactcgggaactgagctcgcaaacacacatcttgttccagatatac agacctcgctgccgttatcctggcctacacctgctgctgcccagctgtggaggtccagca tgttctccgatggctctgtgtgtccccagtgagtccaggagtgctgatccaccttcttgt cccaggctagagcagtggtgtccattccagcaccgctgcttgcccctctcgagtccctgc cagccttcctcctgtctaaactgctcccaggggcaccagcttccctcggaggcgcggatg cccctgtacacgttacagtacgaggtgctgttctctctgacagcaggcccggctgcacat gtgctgcttcaagatcagttggaagacctcctggtgtcccgcggtgatgtcatcgccctg cagcacgatgccggccccgcctccctcatccactgtcagtcctccccgcactccttgtgg cggcaacccgtttttgctctcaacctctctgagtggttcgggatcaacaacacgccggtg ccaccagacaacttggccggtgatggcgctgaccctcttcctgaccccgagctagacttg aaggccctggtggatggtaccagaggtagctggctggagaacgcagtttgccccatcaga gtgctctatgtgggtcaaagtgagactcggctgcggggggcggagctgtcggctggacta cctcagcctggactctacaatctgctggtgacctcagccaagcaatcggacctagtttca gcatcgtgttcactccaggtgctgcctcctctggacttgacagtcctccacccctccccg cagaatggcacgctcttcttggagtcgaacaggacccgactgctgctccgcgtccagtca cgctacgagaccaaggccttttaccgcaccagtaattccagtgcaacattccatccctac tgtccccaagagttttcttcccgcctctgtcatcccagtacgagcgaaggctccggggct gaggtcgcagagcccagcatgtatgccgtgctggatctgaatcttaagataaaggaacac acaggcccggttcaggtggagctgatggcccacaataatgtgacagaggccagcctgact gtgcttgtccagctggaggagtcgctccgaggtctggtggtacagccacaccctgcgcgg agggtgctcatggagtcagttgtgagctacacggcctctgtgttggaaggctctaatccc acttttaaatggacggtggacgacaagccgtttttcacctattacaacacggtgctcaat gttatctaccagcacgccgatgtctacaagctcaccgtgacggccatgaaccacgtcagc accctcacagaggatttcaacgtgactgtggaccggctgcagcccatgacaaacctcacc gtaaagggggtaccagacgtggtccctcagggctccacccagacgctcaccacatctgtg ctcatcgacatggctgtcccggccaccgtccgatggtccttcggtgatggtggatatgag cagtttgaacacaagcctccctacccttcctccctcacctgccctgagtcgccttatcag gtcctcctaagcagcaatgtcacctacatctactctcagccaggcatctacacggcagta gtgtcagtctccaatcgctatgagaacatcagtcgaagcattaacatgagcgtctacagc atcctcacgcgtgtcgacatacagacggagccgagtctcctccttgctgggaaaacggct gatttcgaagctcaccctctgccttcaccctatgggattcattacgagtggaactttgga gacggttctgcactgttgcagggtcggcgagtggcgcacacctttgaaaagagcggcccg tttaacgtgtgtgtgtctgtaaataacaccatcagctctacagcggtatgcacagagatg tttgcatatgaggagatagagtctctaacagcggagagttcctctcccaccgagctccac agcgccaccactgttcgagctcacctctcatcgggcaacaacatcacatggaccttctcc atgggcgacgggaagagctacacactgtctgagccaacggtctcgcacaaatacgccaaa gacgggagattcacagtgaacataactgccatgaatgccgtgagttcgggttggatgatc ataccagtggaggtgtttgtctttcaagtcgccgggatagagccatcaggatgtgtcgga gagcacgcccttgtcaactttcgggcccgggtttctgggaacgcatcggcttatctttac gagtggagcttcggcgatggaagccccaatgagacgcaccacggaaaccccggaatctca cacacgtaccgcggaaatgggacgcatccgctctctctcaccattaccagtggagtaagt aaggccaacttcgttacccaggtgtgcgttcagccggttttaaccaagatcagcgtcacc gccgagaaatcacactttgcggttggagagaagatccaattccaagccagagcagagcca gaatttaactacacttatgagtgggactttgggggagaagaggaccttgttctccctcac gcccctgcgaatgtagtgaaaacctataataacccagggtgttacgtggtgacagtggct gcctctaataacgtttccaacaccaccggcagcgtttcgatcgaggttctgacgcccgtt ggagcagttgtctttcagcacaatggcacccattacaataatctgacccttggggtaccc tactatttctctgcattttcctcagcgtccaatgtctcttacctctggaactttggccac ggtaatttgctcaaaggtcagaacatcctccacactttcaacacgccgggactccacaat attactctgacggcggccaatcgggtcggcaagaatcacaccactgtacctgtcgcggtg ctggcttcggtctctggattgaccatcaattccagtctggtgaacgtccctctcaacacc tcagtccactttgaggcccacatggatgagggcgattctgttcggttctcctggattttg tgcgaccactgtaccccgatctttcgtaataacaccatgttctacacatttcgctctgtt ggcactttcaacatcattgtgacggcggaaaatgatgtaggagcagcacaagcgagcatc tacttgtttgtgcaacgtgagctggagggactccagattcttgtcgagactgcagaagga ggaggaggtggagtacaagagctggactggtgctactttgagaccaaccgcgttgttcgt tttcacgcaggatttaaggaaggaaccaacttgaccttcacctggaacgtcatcctaaag cacgaacctgacagatcaatctttaacctcaccgggaagacagcgaaggtgaatccctca aaaccgggaccatgtgatatctttctccaggcagcaaacctcctgggccaggtcactgtc aacagaaccatctacttcctggaacctgccaggaacgtgcagctgcagatcagcgacaac ccagttgctgtcaacgctctgattaacatgacggtgctgaatacggaaggctcgaacctg cagtaccgctggtttgttaatggagatgatctgcagtggagcaagtcctggatgagccac accttcaccagtgccggccagaagcaagtcaccgtcaaggttttcaatgaagtcagttca gaggtgcaatcggagattgtcagcgtgcaggaggtcatttccgggctgaagatcacaagc gctgatgctacagagcagaattatttcccaaccgatgtcagcgtttgtctccagggtgag gtgtcaacgggaaccaacgtgacgtggtcgtggttgatcgacggaatgtccaaaatgcaa aagaaagcctgcgtggctttcccaaagcctaaaacagtggccgtaactctaaatgctacc aacgacgtgagtggaaaagtggtttccagagagttctttgttcaggagagaattttcagc ctggagctcaaggccagtaagaagatcgcagcaataaatgagaaagtggagttcagcatc tccctggtggcaggcacaaacgtcaatctcagcctcagcatcagtagggacgccactgtc gtccttcaacccaaccaaacctacgtccacactttcagcagggtggatacctacatggtg aatctcacggcttataatgaggttagctgcaagaggcggaatctccacattgaggttatg gagccggtgcggggactttccatccaagatagctgcgccgccatcgctgtcggtgaaaag aaagtgtttgttgccaacgtccagactgggaaacctgttcatttcctgtggacatttgat cttcatcacctccacaaggaaacacacatgggcaaagagttcagagctaatccatccttc ggggctggcaccatggtgttctacacagcagaagaggagggtttactgaccatctacctg ggagccataaatgcgctgcatgctcagaacatcaccagacagatgctggcgcagaatgtg ctgatggacgccgtcttgtacgcgctgcctcaggacactttcgtcaataaaatggtcacc atgaatgtcttggtcacccccaaatcgaatttcatggactgcttgtggatctttggagat gtttcagctccacgtcacaccaacaacaccaccgtgggtcatgagtacacgcacccggga cactaccgagtccaggtgaactgcagtaacctggtgagctgggtttcggcccacgctgag ataaacgtcagtgtgctggagtgtgaggagcctgaggtacaagtggtccaagccccccgc ctggctatatggcgctcccagcccactctggtggaagccagcgtggatcttaaaggatgc ctgcgctatggagcccagtacctctggcagatactctcagcaccgtcgtgcgataatgac ccccattttgcatctgggcgggtgaacggggccactcggtctttcccagtaattcctttg ccagcggaggtggatgtgcagcggctgcagctgtcgctccctaagatggtcctggcggca ggcaactacaccctggtgttctccttgtcctatgaaaacgtgccgttaaagaaagccgcc tgtctacagcttggcgtcatggctgcccgactgatgccgattatagaagggggcacctac agggtgtggtccagaactcaggacctgcagctcagtgccgagcagtcctacgatcccaac atggaccctgacaaccagtccctcctccactatcactgggagtgtcaaagcacctcaaag ggtccagaacactgctccactctgagcttcggcctgggatccaaaggtccggtgttggga atctctggttctgagctggaagcgggcattgagtacactttcaaactgtcaatcggcaaa gaagggatgccaccagagtccactacacagacggtgcttgtccagagtggtcacattccc atggtgtatctggaatgtgtttcctgcaaggcccagtccctgtatgaggtcagccagaac tcgtacgtctacctcagagggacctgctctaactgccagggctttcaccgcgggcgctgg agtgccgtgacgcttcagaacgacactttggtcctggactcgtcctccaccaccacagga agcggcggcatgaacctggttctgcggcagggcgtgctgcacctcggggagtcctacaat ttcaccctccacgtgaccgatgacagtctggacggcgagggagctgcctccatcactctt caccacaatatgcccccagacggtggagagtgtcacctgaggaggggaggggaaaccggc caggagcacggagacaaagaagatgaagtctggaggatagaaacgctgttggaccgtgtg cagttcagctgctcaggttacagtgatctgggagtctcagagacccctctgctctacagc ctgctggtgaaccgctgcagggacgactactgtgaggagttctacgtgtacagaggcagc agcccagagcactcagccttcctgcctccaggcttcagctcagcccaacaccgcgtgtct gttttcatcacggtggaagaccaccagggagccgccattagggcactcaacaagaccatc aaggttgtgttgccagatccgccccccgagtacagcagccttcctcattggctgtcggac ctgatagacagcaaactcaaaaaattgttggatcaaggagacttccaacgggtccgagag ctgtccctagttcttattactgtcctcaatgagtatgagcagacacgagaatctgtgcga gtgtcacgggttgagcgtggttaccgagggagggtccgcaacaacatcaccagagctctg accgctctagacctgaccaccgttaatgacatccagcagacctctgcggcgttggctcaa tgcacggcggtgagccgtgagttcatctgtgaggagtgtcagaacagtactctgaacaag ctggagtccatgctcgagatcctgcaaacggacaccaaacagggcatcgtcaccccgact gagatagctgacaacattctgaacattatgggtgatttgatccatcaggtgagccaatcg acatcccagtcttacaaccaaccgccgtacgtggattccccgtcgccctcgttcatcccg aaggatatgggaggtttggacccttctcccccctcgctggagccgcaccccttgcgagtg gcggccaaggcgtacagcttatcctcggttctcatgctgatcctcatgcacgcccgcgtc cttaacgaggagccgctggtgctgaagggagctgagattgctgcaactggaaaattggca gaccctcagagcctgctctgttaccatgggaacaacagtccagactgccagctgttctcc attcccagagctttcaacaacagtcttggcaaagccgctgcaggacgcagcgtcatgcag ctcctgttccaggtggaatccaaccccttccccttcaactatgtggccaactacaccgtc tccaccgaggtggcgtccatggagttccgcacagaaaacggaacccacattccaatctct ggactggatgacagtttagccattacggtcgccgttaacaacgggagtaacggagcagag accggtcccgagggtgctggaacagggggggtgccgacagcaggagcggtgaacatcagc tcctgtgactctgtcattgtgagagtcagcgtggggaacaccaacagacgcgcagggctc tttgtgcagctcaacttcacctctctacaagatgtcggtctccaggataagagggaagat gcagaggagttgagcatcacggcctatctgcactcgcatgaaaaacccaacgagtttaac tgcaccgacaggaaaaggatcacgctcggtatgaccaggggtcatgacctggaccacagg aaatacaccttcttcctgtcgccagagttgtacgacaccacgctggactattttatcaac gtgagcacggcctgcggatccggctccggggccgccggcgtccgtctggaggtcggggtt ttcgcctctctgtgccagtacttcagtgagagcgagaagcagtggcggacagatggcatg gtgcccctggcagaaacaaacgccagcagagccgtttgccgtaccagacacctcaccgca ttcgctgcgggcctgttcgtgccggccaatgcgatcagcttcacggtcccagagcgctct ggtacgccgagcttggtcgtcctgttggtgtgcgtgctgggcttaatgtcttatgtcgtg gcagcagccattttgcacaagctggaccagctggatctgcgtcgggctgcggtggttcca ctctgtggctgcgatggcctctttaagtacgagattcaagtcaagactgggtggagccga ggggctggcaccacagctcacgtgggaatcagtttatatggacgcgagagccgcagcggt caccgccatcttgacagcaggggatccttcgcgcgaaatgccctcgacatctttcatatc gccacagacaccagcttgggcaacgtctggaaaatacggatttggcacgacaacaagggt ttgtccccagcgtggatgctgcagtacgtcctggtcaaagatctgcagacaggaagcagc tcctacttcctggtggaggagtggctgtctgtcgacaatgagaaaacggacgggcatgta gagattgaggtggaggcctcggaagaggctatgcttttgcagctgccacgtcttctcaga tatgagctgcagagggcgctgtgtgagagccacctgtggctgtcgctgttccagagaccc ccgcgcagccctttcacgcgcctgcagcgagccacctgctgcgcgctgctgctgcagctg ctgctgttggccaacactttgtggtacagcatcgtggtggacgtgagatacagcccgcga cctgtgtctaggttcgcttcactcagtggcgagacggtggccgtgggcgtggtcacctgt ctggtggcgtaccctctctacctgctcgttttcacgttgctcagaatgagccgcagcaag tgtgtgtctgtggagcaggtgccgccacaggtggaccaggaatcagtggagatcgatgat ttcctggacaattccatgggtggaacttccttcctcttttacaatggcgagaccaactcg gaggaaaccaatgtggacctgccctcgccatcaaccaggagtgtggaaagttgggacatg acagaaggggagatggaggtcagggactggccagacctgttgagcgatgcccccgccatg ggaggggtggggtgcggtgcagggctgcccaggctgaagaggggtcagggcagcaggcac ctgggtgtcgacatggcctttaacgcagacaacgaggatggagccaaccagcggcacaaa cacttcacctcgtcggacgaggatctgatcaaacacatcctgacagacggacaccgcttc ttctctcagcctgatgaaagcgagatggccgacctgtcgagcatttttgaagatcagacc gaagtgattctcctgcagaaacaccatgagcctcttcctctggagtctgtgcgaagagac ccgccaagaaccgcattcacctcaaacacagttgtgacagatgtgtgccgtccccgccgg tttcccccttcgtgcggccgtgctgccctgtggggtagttggacggggatcgctctggcc agcggcgtgtccatgtgggcgggtcgagggttcactcagaacgttgccatgttgtggctc ctctcctgtttcgccagtttcctgtgctcctgcctgctgttggaaccaataaaggtggcg tgtgaggccgtctattatgctgtgtatgtgcgtcggctgcgtcctgaggaccaggacgtg ctggtggagttccctcgggttgagagggtggtccaacgtgtctccaaggtgagaccacct cagggatttgctctttcccaggcccgacagcaggcccgcaaagtccacatgctgcacacc atgctgaagaatttcctggtttatacgttcttcctgttggtggttttgctgctcaactac tcggactccgacaaggacgcgcacagcttgagactgcgcacgcagctccaacgagcacta cgcacgcccgagtaccgcggcgtcagcagccgaggcagtgttctgctgtggctcaaccag tcgctgtttccacggctactggacgactcggccctgttaagagacacgggaagcgtcttg ctcggcacgttgagactccgccagatctttgacaagcaaaatgacgtcatcccggaagtc ggcggagacggcacggcagagaacatcaccgattatcggaatatcagtgcagtgaatagc gttccacgagcgtggcggtcaggtcggttaaaggcgaacgacagcagagacgtgctgcag ctgaacgggagcctgggggaggccttttcctccttgcagcagcaccactggctcgaccaa aggacccgtgctgtggttgtggagttctcgctgtacaacatcaacacaaatctcctggcc gtcttctccttcctaatcgagtttccggtctccgatcgggctctgtccagcatggacctc cacgtcatcaccctgtggccattcacaggcctggacctgcagctccttctcacgatcatc ctcctcgctctggttttatatttcctggtaccaggcgtcacaggtttcctaagagaaggt tacacctacctgctgtccacctggagagctctgggcatctgtaaattggctctggcggca tccgtgtgtgggctccacctgagtcgctgcgctatggccacgcagctgtggacgctgtac gtgaagcatccacacgacgacttcacagacttctaccctctggcccgacagacacagctg tacacagtcgccagcgctttgctgctgttcgtgtttgtgctcaaggtttcccaccagctg cggttcctccgggagtgggccgtgtttggcagagctctgcgccactcggtccgggagctg ctggccgtggccttcgcgttgctgctgctgctgctggcgtactcgcacgcaggccacctg cttcttcactcggtcatcgatggctacaacagtgtgacctccacttgtctgtccttggtg ggcaccagtggacgcactctgctctcgtggcgtgccagctggactactaccgggccctcg aacaccatctcctccctggttttccacacaacgtttgccattcttcgtctggcgttcctc tggctggtgatatcggtgctgctgaggaattaccagcgcgcgcgagcggagctgtaccgt ccggctgtggatctccaggactacgagatggtggagttattcctcaggcggctcaaaatg tggatggggctgagcagagccaaggagttccgtcataaagttcgatttgagggaatggag ctgccgccctctcgatcatcctccaccggtgactgtaagtccctgtgcttgccgccactg gatgctcccgagtcccctcctacgcctgacagcatcgacgctggctctgaggcctcgtgg cgcccggcttcctccagcccctgtagtttgacagaagcccctggggtgagcctgggactt ggactgggtctcggtctgaacctcagtcctggagtaatgatggggaacgttaactggagg gagagagcagaaactgaagcctctctgaggaggctgctccccaccctggatgccctcctg cagcagcttgaccgggtcaccgtggcaacagaggatttataccacgtggagtgcagatta gaacgtgcgcagagcaaaaggagacacgcgggatcggagaaaggaggggccgctcaggga agcagcggcgacagggtggagaccgcgggcggatggagggagcgaaagaggggcaaagaa aagcacggcgtggggaagaaggtggagaagagtgaacttccgaaagacggaagcgcttcg gccaatctgaaaaagactccagcggccgcctccagtcccttctcaaagcctcgttcggct cctgactcccacctcccccggaccaacacgcccactgtacctccaaccacccctgcaccc actccgcctcccctgctcgcacccaacgctcagaactgggacccccccgtggaaagagat acgcctccgtcctccagtctgttcaaccacccggctcacaccaccaccatcccgacacgc aaaaggaagcgtaaaaccccgcctctaaaaaataaagtgcaccccaacctggacaagcac agcccaggacacccaaagccctga

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