Takifugu flavidus (sansaifugu): 130533676
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Entry
130533676 CDS
T09160
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
tfs
Takifugu flavidus (sansaifugu)
Pathway
tfs00270
Cysteine and methionine metabolism
tfs00480
Glutathione metabolism
tfs01100
Metabolic pathways
tfs01240
Biosynthesis of cofactors
tfs04216
Ferroptosis
Module
tfs_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
tfs00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
130533676 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
130533676 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
130533676 (gclc)
Enzymes [BR:
tfs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
130533676 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
130533676
NCBI-ProteinID:
XP_056903274
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Position
11:13520668..13526983
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AA seq
630 aa
AA seq
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MGLLSVGSPLNWEETKKYADHIRKHGIIQFLNIYNKVKERQKDVLKWGDEVEYMLVEFDD
EEEKVRLTLNSGHLLETLQDQGERINPNHPTLWRPEYASYMIEGTPGQPYGGTMSEFNTV
EGNMAKRRREASSLLDHNQTLCTITSFPRLGCPGFTKPEYRPSPVESRVAKSLFFPDEAI
NKHPRFSNITRNIRHRRGEKVVINVPIFKDKCTPSPFVEEFPEDDGEAAKAALPDHIYMD
AMGFGMGNCCLQVTFQACSINEARYLYDQLATFCPIVMALSAASPFYRGFVSDIDCRWGV
ISASVDDRTPEERGLMPLKHNKYRIFKSRYDSIDSYLSTCGEKYNDIVLTIDEEIYAQLL
DAGIDKLLAQHIAHLFIRDPISVFKERLNLDDENDSDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENAAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAV
LEGMFYFRKDIFKGCNPVLDGSGSAQNGLEGECANEEYTLMSIDNIINGKEGVFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKKRASGELMTTAKWMREFVANHPQYKEDSVITDKI
NYDLMVKCNQIAKGDEMCPELIGNPVNKFK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggtctgctgtcagtgggctctccgcttaactgggaggaaaccaagaagtatgccgac
cacattagaaagcacggcatcatccagttcctgaacatctacaataaggtgaaggagcgg
cagaaagatgtgctgaagtggggcgatgaggtcgagtacatgttggtggaatttgacgac
gaggaagaaaaggttcggctcacgctgaacagcggacatcttctggaaaccctccaagac
caaggggaaaggataaaccccaatcacccgacgctctggagaccggagtacgccagctac
atgatcgaaggaactccaggacagccttacggcggcaccatgtcagagttcaacaccgtg
gagggcaacatggcgaagagacggcgagaggcctcttctctcctggaccacaaccaaacc
ctctgcaccatcacctcctttccaaggttaggttgtccaggttttaccaagccagagtat
cggccaagtcccgttgaaagcagagtggccaagtcgctctttttcccagatgaagccatc
aacaaacacccaagattcagtaacattaccagaaacattcgtcacagaagaggagagaaa
gtggtgataaatgtccccatcttcaaagacaagtgcactccatctccatttgtggaggag
ttccccgaggacgacggggaagctgccaaggcagcgctgcctgatcacatctacatggac
gccatgggcttcggcatgggcaactgttgcctgcaggtgacattccaggcttgcagcatc
aatgaggcaagatacctttatgaccagctagcaacattctgcccaatagtgatggcgctg
agcgccgcctcgcccttctacagaggctttgtgtcggacatcgattgccgctggggagtt
atttctgcatcggttgacgaccggacgccggaggaacgggggctaatgcctctgaaacac
aacaaatacaggatcttcaagtcgagatacgactccatcgacagctacctgtcgacctgc
ggggagaagtacaacgacatcgttttgaccatagacgaggagatctacgcacagctgctt
gacgcaggaatcgacaagctgttggcgcagcacatcgctcacctgttcatccgagatccc
atctccgtcttcaaggagagactcaacttggatgacgagaacgactccgatcatttcgag
aacctgcagtccaccaactggcagacgatgaggttcaaaccgccccctcccaactctgac
atcggctggagggtcgagttccgccccatggaggtgcagctgaccgactttgaaaacgct
gcctatgtggtctttgtggtcctgctcaccagagtgatcttatcctacaaactggacttc
ctgattcctttgtcaaaggtcgacgagaacatgaaggtcgcccagaagagaaacgctgtc
cttgaggggatgttttacttcagaaaggacatctttaaaggttgcaacccggttcttgac
ggctccggttccgcccaaaacggcctggagggggagtgtgctaacgaggagtacacgctg
atgagcatcgacaacatcatcaacggaaaggagggggtgttccagggactcattcccatc
ctcaactgctacttggagaacatggaagtcgacgtggacacccgctgcacgattttaaac
tatctgaagctcatcaaaaagcgcgcctcaggagagctgatgaccacggccaagtggatg
agggagtttgttgccaaccatccgcagtataaggaggacagcgtcataacggacaagatc
aactacgacctaatggtgaagtgcaaccagatcgccaagggcgacgagatgtgcccggag
ctcatcgggaaccctgtcaacaagtttaaatga
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