Thermobifida fusca: Tfu_1106
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Entry
Tfu_1106 CDS
T00265
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
tfu
Thermobifida fusca
Pathway
tfu00300
Lysine biosynthesis
tfu00550
Peptidoglycan biosynthesis
tfu01100
Metabolic pathways
tfu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tfu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Tfu_1106
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tfu_1106
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tfu_1106
Enzymes [BR:
tfu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Tfu_1106
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
PRP4
Motif
Other DBs
NCBI-ProteinID:
AAZ55144
UniProt:
Q47QX3
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Position
1289563..1290975
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AA seq
470 aa
AA seq
DB search
MIALTLDRIAKITRSRLRGSAQPTDTVDGPVVIDSREAAPGSLFVALRGSRVDGHDFAEA
AVRAGATAVLCSRPVDAPHLLVDGGDDAVVAALAKLARAVVAELPDADIIGVTGSSGKTT
TKDLLAQTLQRIGPTVAPPGSFNNEIGHPLTVLRADQTTRFIALEVAARGVGHIAHLCQI
APPRIGVVLNVGSAHMGEFGSRDTIAQAKGELVEALPAAAQGGVAVLNADDDAVIGMASR
TAARVVSYGLAPDADVRAEGIALDERGRPRFTLAIGEDTAPVSLRLVGTHQVHNALAVAA
VLRELGEPVTAIAAALSEAGPVSRWRMEVTERPDGVTIVNDAYNANPESMSAALRTLATL
ASGRRAFAVLGHMAELGSAHRTEHERIGRLVTESGVDVLITVGEQAASIADGAASVADWK
GETVTVADVTEAVAVLKERLRPKDIVMLKGSRVAGLEQVAEQLIDVEAAE
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
ttgatcgcgctgacgctcgatcggatcgccaagatcacccgatcacgactacgcggatcg
gcgcagcccacggacactgtcgacggcccggtggtcatcgactcgcgggaggccgctcct
ggttcgctgttcgttgccttgcgaggcagccgtgtcgacggccacgacttcgctgaggcc
gcggtcagagccggagcgacagccgttctgtgctcccgccccgtggacgcgccccatctg
ctcgtcgacggcggcgacgacgcggtagtagcggcactggcgaagctggcgcgcgcggtc
gtagcggaactccccgacgcggacatcatcggcgtcaccgggtcgtcggggaagaccacg
acaaaagacctgctcgctcagacgctgcagcggatcggccccaccgtcgcgcccccggga
tcgttcaacaacgaaatcggtcatccgctcaccgtgttgcgggcggaccagaccacccgt
ttcatcgcgttggaggtcgccgcgcgcggcgtgggacacatcgcgcacctgtgccagatc
gcgccgccacgcatcggagtcgtgctcaatgtcggcagcgcccacatgggcgagttcggc
agccgggacaccatcgcccaggccaaaggcgaactcgtggaagcgcttcccgcggccgcg
caaggaggggtcgccgtcctcaacgccgacgacgacgccgtcatcggcatggcctcgcgc
accgcagcgcgagtcgtgagctacggcctggcccccgacgccgacgtgcgggctgaaggc
atcgccctagacgaacgcgggcgtcctcgcttcaccctcgccatcggcgaggacaccgcc
cccgtgagtctgcggctcgtcggcacccaccaagtgcacaacgccctggccgtcgccgca
gtcctccgcgaactcggcgaaccggtcaccgctatcgccgcggcactgagcgaagccgga
ccggtgagccgctggcgcatggaggtcaccgagcggcctgacggcgtaaccatcgtcaac
gacgcctacaacgccaaccccgaatccatgagtgcggcactgcgcaccctggcgacgctg
gcctccggccgccgcgctttcgcggtcctcggccacatggccgaactcggctccgcgcac
cggaccgaacacgaacggatcggacggctggtgaccgaaagcggagtggacgtcctcatc
accgtcggagagcaggccgcgagcatcgcggacggcgccgcctccgttgccgactggaaa
ggggagaccgtcacggtcgccgacgtgaccgaggcggtcgcggtgctcaaagagcgtctc
agacccaaggacatcgtcatgttgaagggatcacgagtggctgggctggagcaggtagcc
gagcagctgatcgatgtggaggcggctgaatga
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