Thermococcus gammatolerans: TGAM_0756
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Entry
TGAM_0756 CDS
T00920
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase II, purL component (purL)
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
tga
Thermococcus gammatolerans
Pathway
tga00230
Purine metabolism
tga01100
Metabolic pathways
tga01110
Biosynthesis of secondary metabolites
Module
tga_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
tga00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
TGAM_0756 (purL)
Enzymes [BR:
tga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
TGAM_0756 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACS33258
UniProt:
C5A4U6
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Position
715595..717733
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AA seq
712 aa
AA seq
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MFPHEEKLIRERLGREPNELEWAMLEVMWSEHASYKSSRPWLKLLPTENEHVILGPGEDA
GIVKFDDETWVVVGIESHNHPSAVEPYGGAATGVGGIVRDILCMGARPIALLDPIRFGPL
EKERNRYLFEYVVKGIADYGNRIGVPTVGGETEFDESLDSYTLVNVACVGIMRPEHLVHS
YVTEAGLKLILVGNRTGRDGVHGVTFASEELSENTEEDRSAVQIPDPFTEKLLIEATLEA
VYTGRVKALKDLGGGGLTCAASEMAGKKGFGAVIYADRVPLREPGMTPTEVMISESQERM
LFAVKPEDVEEIGRIFEEYELEWTVVGETIEEPRFVVYWKGEKVADLPIELLTEVPTIEW
ELKPYSAEGPVETPDVPFERAFDLVWGSPNILSKRWVWEQYDHEVQGRTVLKPGRDAAVL
KINDEYGLAFVADGNPNHSYLNPYQGAMGAVAEVVRNLVSVGAEPLALVDNLNFASPERP
EVYWSFAETVRGLADAARAFGLAYVSGNVSFYNEVVDRPIKPTPVVAGLGKVKLEAIPNG
GFEEGLLIGVVGLTKPELGGSELFARLGVEGGLAPRVNLEEEKANANGVLEAIRRGLVRA
VHDVSRGGLAVALAKMAVAGNTGFTADLSKVPSETTNPIEVAFSESHGRYIVAFPEENLE
ELKGLFKHFVIIGRTGGSDAVFLWNGWELLRKPVSELKAVHESLPMLLGEEE
NT seq
2139 nt
NT seq
+upstream
nt +downstream
nt
atgttcccgcacgaggagaagctcatccgcgaaaggctcggcagggagccgaacgaactt
gagtgggcgatgctcgaagtgatgtggagcgagcacgcatcgtacaaatccagcaggccc
tggctcaagctcctcccaacggagaacgagcatgtgattttgggcccgggtgaagatgct
ggaatagtgaagttcgacgacgagacgtgggtagtcgttggaatcgagagccacaaccat
ccaagcgcggtcgagccctacgggggagcggccactggagtcgggggaattgtgagggac
atactctgcatgggcgcgagaccaatagcgcttctcgatcccatacgcttcggcccgctg
gagaaggagagaaaccgatacctcttcgagtatgtcgttaagggtatagccgactacggc
aacaggataggcgttccgaccgttgggggcgagacggagttcgacgagagcctcgacagc
tacacgctcgttaacgtcgcctgcgtcgggataatgaggcccgagcacctcgtccacagc
tacgtgaccgaggcaggactcaagctaatcctcgtcggcaacaggaccggcagggacggg
gttcacggcgtcaccttcgcgagcgaggagctgagcgagaacaccgaagaagaccgctcc
gcggttcagattccagatccgttcacagaaaagctcctcatcgaggccaccctcgaggcg
gtctacacgggcagagtcaaggcactcaaggatttggggggcgggggactgacctgcgcc
gcctccgaaatggcgggcaagaagggcttcggggcggtaatctacgcggacagggttccg
ctccgcgagccggggatgaccccaaccgaggtcatgatctccgagagccaggagaggatg
ctcttcgcggttaagccggaggacgtcgaggagataggcaggattttcgaggagtacgag
ctcgagtggaccgtcgtcggcgagacgattgaggagccacgctttgtcgtctactggaag
ggtgagaaggttgcggatttgcctatagagcttttgacagaggttccaacgatagagtgg
gagctgaagccttacagcgccgaggggccggtcgaaactcccgacgttccctttgagagg
gccttcgacctcgtctggggcagtccaaacatcttgagcaagcgctgggtctgggagcag
tacgaccacgaggttcaggggagaacggttcttaagcctggaagggacgcggcggttctt
aagataaacgacgagtacggtctggcctttgtagcagatggaaacccgaaccacagctac
ctgaatccctaccaaggcgcgatgggggccgttgccgaagtggtgagaaacctggtcagc
gttggggccgagcctttagcgctcgttgacaacctcaacttcgcatcgcccgagaggccc
gaggtctactggagcttcgccgagaccgtcaggggcctggctgacgcggcgagggccttt
ggcctggcgtacgtcagcgggaacgtcagcttctacaacgaggtcgttgacaggccgata
aagccgactcccgtcgttgccggcctcgggaaggtgaagcttgaagctattccgaatggg
ggtttcgaggagggcctcctcattggcgttgtaggcctcacgaagcccgaactcggcggt
tctgagctcttcgcgaggctcggcgttgagggtggcctcgcaccgcgcgtgaacttggag
gaagaaaaagccaacgcgaatggcgtccttgaggcgataaggaggggcctcgtcagggcc
gtccacgacgtgagcaggggcggcctggcggttgccttggccaagatggctgttgccggg
aatactggcttcaccgcagacctctcgaaggttccctccgaaaccactaacccaatcgag
gtcgccttcagcgagagccacgggcgctacatcgtggcgttcccggaagagaaccttgag
gagctgaagggcctcttcaagcactttgtcatcatcggaaggacaggaggaagcgacgcg
gtcttcctctggaatgggtgggaactccttagaaaacccgtttcggagcttaaagccgtt
cacgagtctctaccaatgcttttgggtgaggaggaatga
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