Theropithecus gelada (gelada): 112607902
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Entry
112607902 CDS
T08041
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
112607902 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
tge03021
]
112607902 (SETX)
Enzymes [BR:
tge01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
112607902 (SETX)
5.6.2.5 RNA 5'-3' helicase
112607902 (SETX)
Transcription machinery [BR:
tge03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
112607902 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
ResIII
Helicase_RecD
AAA_16
nSTAND3
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
112607902
NCBI-ProteinID:
XP_025215010
Ensembl:
ENSTGEG00000013724
LinkDB
All DBs
Position
15:6442237..6541173
Genome browser
AA seq
2709 aa
AA seq
DB search
MSTCCWCTPGGGSTVDFLKRYASNTPSSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFEKSMKAEIGDDDELYIVDNNGEMPLFDITGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNDMVRRWAILTARNLGK
VDRDDYYDLQEVLICLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKSYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNASYNREIQHIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRTAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVVHHLYSEVKDVLNQTDAMCDKVTEFFLLILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFTRSSEKSSGNCSKGTPMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGQQSLCKRFWDKLNLFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKFKAP
PCNTFVDLTSTCKTSPASYNKEESEQIGKKSRRDMHCLEASSPTFSKEPMKAQDSVLIKA
DNTIEGDNDKQNYIKDMKLEDRLSAGSCLKQSSENIFTERAEDEIKISTRKQKSVKENSS
YTPEDCTSRNGPERGCDRGIIVSTRLLTDSSTDALEKVSTSNEDFSLKDDALAKTSKRKT
KVQKDEICAKLSHVIKKQHRKSTLVNNTINLDENLTVSNIERFYSRKDTGVQKGDGFIHN
LSLDPSGVLDDNKNGEQKSQNNLLPEEKQLKNEELDIFCSHENNCEIQEFHVDDKDSIPF
TEMANTLEKKSSSFKDLMTVPESRDEAMSNSTNVIYSNLTREQAPGISPKSDTLTDSQID
RDLHKLSLLAQASVITFPSDSPQNSSQLQRKGKEDKRCFTANQNNVGDASRGQVIIISDS
DDDDDDERILSLEKLTKQDKRCLEKERPEQHISTVKEEKNPIKEEKTKSLFQFEESDSQC
FEFESASEVFSVWQDHLDNNNSVQDGEKKCLTPIANTTNGQDCTDYVSEVVKKGAEGIEE
HARPQSSRVSVEEFCEIEVKKPKRKRSEKPIPEDPVRPSCSVGNEGQSDINKRGLIGNDF
KSIDRRTTTPNSSIQRTTTVSQKKSSKLCTYTEPVRKVPVSKTPKKTHSDAKKGQNRSSN
YLSCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKGPRRAFELSQRSLDYVAQLRDHGKTVG
VVDTRKKTKLISPQNLSVRNNKKLLTSQELQMQRQIRPKSQKNRQRLSDCESTDTSGAGP
HTAQNSDLLVPESDRSDYDCTGGTEVLANSNEKQLIKCMPSEPETIKAKHGSPATDGACP
LNQCDSIVLNGTVPTSEVIVCTSEDPLGGGDPTAHHTEMATLNEGEPDSSSDIEEENLFL
TQNDPEDMDLCSQMENDNYKFIELIHGKDTVQVEEDSVSQPQLESLSGTKCKYKDCLETT
KNQGEYCPQHSEVKAADDDVFRKPGLPPSASKPLRPTTAKIFSSKSTSRIAGLSKSLETS
SALSPSLKNKSKGIQSILKVPQPAPLVAQKPVGEMKNSSNVLHPQSPNNSNRQGCKVPFG
ESKYFPSSSPVNVLLSSQSVSDTFVKEVLKWKYEMFLNFDQCGPPASLCQSISRPVPVRF
HNYGDYFNIFFPLVVLNTFETVAQEWLNSPNRENFYQLQVRKFPADYIKYWEFAVYLEEC
ELAKQLYPKENDLVFLVPERINEEKKDAERNDIQDLHEYHSGYVHKFRRTSVMRNGKAEC
YLSIQTQENFPANLNELVNCIVISSLVTTQRKLKAMSLLGSRNQLARAVLNPNPMDFCTK
DLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLL
YCLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGN
CGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQAMHKRKEFLDYQLDELSRQ
RALCRGGREIQRQELDENISRVSKERQELASKIKEVQGRPQKTQSIIILESHVICCTLST
SGGLLLESAFRGQGGVPFSCVIVDEAGQSCEIETLTPLIHRCNKLILVGDPKQLPPTVIS
MKAQEYGYDQSMMARFCRLLEENVEHNMISRLPILQLTVQYRMHPDICLFPSNYIYNRNL
KTNRQTETIRCSSDWPFQPYLVFDVGDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDV
SFRNIGIITHYKAQKTMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANSVQG
SIGFLASLQRLNVTITRAKYSLFILGHLRTLMQLLPRSFCVHVNHSPFFSPEPKYLHWAL
KENQHWNQLIQDAQKRGAIIKTCDKNYRHDAMKILKLKPVLQRSLTHPPTIAPEVSRPQG
GLPSSKLDSGFAKTSFAASLYHTPSDSKETTLTVTSKDPERPPVHDQLRDPRLLKRMGIE
VKGGIFLWDPQPSSPQHPGATPPAGEPSFPVVHQDLGHVQQPAAVVAALSSHKPPVQGEP
PAASPEASTCQSKCDDPEEELCHRREARAFSEGEQEKCGSKTPHTRRNSRWDKRRPEQED
SSSKKRKLL
NT seq
8130 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtactccaggtggtggttccaccgttgacttcctaaagcgc
tatgcttccaacactccatccagtgaatttcaaacagctgacgaagatctctgctactgc
ttagagtgtgtggcagaataccacaaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattggaaaccttacgtctgataaatcactttgaaaaatccatgaaggcagaa
attggagatgatgatgagttatatatagtagacaacaatggagagatgccactgtttgac
atcactggacaagactttgaaaataagcttcgggttcctcttcttgaaatactgaaatat
ccttatttgcttctacatgaacgtgttaacgagttatgtgttgaagcactttgtcggatg
gaacaagccaattgctcctttcaggtgtttgacaaacatccagggatctatttgtttttg
gtccatcccaatgatatggttcggcgttgggctatcttgactgcaagaaacttggggaaa
gtggacagagatgattattatgacttacaagaagttttaatttgcctttttaaagtcatt
gagttgggacttctagagagtccagacatttatacttcttctgtcctagagaagggaaaa
ctaattcttctgccctcacacatgtatgatactaccaactacaaaagctattggttaggt
atttgcatgttgctgaccattcttgaggaacaagccatggattccctattgttgggctca
gacaaacaaaatgattttatgcaatcgatacttcacactatggagaggcaatcagatgat
gatagtgtggatcctttctggccagcattacactgttttatggtgattctggaccgcctt
ggatctaaggtctggggtcagcttattgatcctattgaggcatttcaaaccattatcaac
aatgcaagctacaatagagagatccaacatatacggaacagctctgtaaggaccaagtta
gaaccggagtcgtatttggatgatatggtgacttgcagccagatcgtatacaattataat
cctgaaaagaccaaaaaggattctggatggagaacagccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctgtggttcatcccttttgtccagtccctcatggat
cttaaggatttgggtgtggcttacatagtagaggttgttcatcatctgtactctgaagtc
aaagatgtcctcaaccaaacagatgccatgtgtgacaaagtcactgaattttttcttcta
attttggtatcagtgattgaactgcatagaaataaaaaatgtttgcatttgctgtgggta
agttcccagcaatgggtagaagctgtcgtcaaatgtgccaagcttcctaccactgcattt
acacggagttctgagaaatcatctggaaattgctccaaaggaacaccaatgatatcatca
ctgtcgttgcattccatgccatctaactctgtacaacttgcttgtgtgcagctgattaga
agtctccttaaagaaggttatcagcttgggcagcaatctctttgcaagcgattctgggat
aaactcaacttattccttagaggaaatttatctctaggttggcagttgactagtcaggaa
acccacgagctacaaacttgtttaaagcaaattattagaaacataaaattcaaagcacct
ccatgtaacacttttgtggatctgacttctacatgtaaaacctctcctgcatcttataat
aaagaagaaagtgaacaaatagggaagaagtctagaagagatatgcattgtttggaagct
tccagcccaacattttctaaagaaccaatgaaagcgcaagacagtgtactgatcaaagca
gataacactatagaaggtgacaatgataagcaaaattatataaaggatatgaaactagaa
gaccggctctcagctgggtcatgcttaaagcagagtagtgaaaacatttttactgaaaga
gctgaagatgaaattaaaataagtacaaggaagcagaagtctgtaaaagagaactcctca
tatacaccagaggattgtacttcaagaaatggtccagaaaggggatgtgacagaggaata
atagtatcaacacgtttgttgactgattctagcactgatgctttggaaaaagtgtccaca
tcaaatgaagatttctctttaaaggatgatgctcttgctaaaacctcaaaacgaaaaact
aaggtacagaaagatgaaatctgtgcaaagttatcacatgtaataaagaagcaacacagg
aagagtactttggtcaataatactatcaatttagacgaaaatttgactgtatctaacatt
gagcgtttctattcaaggaaagatacaggagttcagaaaggagatggtttcatacacaat
ctttctttagaccctagtggtgttctggatgataataagaatggagaacaaaaatctcaa
aacaatttattgccagaagagaagcaattaaagaatgaagagttagatattttctgttcc
catgaaaacaattgtgaaatacaggaatttcatgttgatgataaagattcgatccccttt
acagaaatggccaatactttagagaagaaatcatcttcctttaaagatcttatgactgta
cctgaatcaagagatgaggcgatgagtaatagtaccaatgtgatttattctaacttgaca
agagaacaggcccctggcatcagtcctaaatctgacaccttaacagattctcagatagac
agagaccttcacaaattatctttactagctcaagccagtgttatcacgtttccgtctgat
tcccctcagaactcatcccagctacaaaggaaaggaaaagaagataaaagatgtttcaca
gctaaccaaaataatgttggcgatgcctcccgtggacaggtgattattatttcagattct
gatgatgatgatgatgatgaaagaatcctgagtcttgagaaactcactaaacaggacaaa
agatgccttgagaaggaacgtccagagcagcacatttcaacagtcaaggaggaaaagaat
ccaataaaggaagaaaagacgaagtctctttttcagtttgaggaatctgattctcagtgt
tttgagtttgaaagtgcatctgaagtgttttccgtttggcaagatcatctagacaataat
aattcagttcaagatggtgagaaaaaatgtttgactcctatagccaataccacaaatggt
caggattgtacagattatgtatctgaagttgttaaaaaaggggcagagggtattgaagaa
cacgcaagaccacagagcagtcgtgtttctgttgaggaattttgtgaaattgaagtaaaa
aagcctaagagaaaacgatctgaaaaaccaattcctgaagatcctgtgaggccttcatgt
tctgtcggaaatgagggccagtctgatattaataagagaggtcttattggaaatgatttt
aaaagtatagatagaaggactacaactcccaattcaagtattcagagaaccactacagtt
tcacaaaagaaatcttcaaagctttgtacttatacagaacccgtcaggaaagttccagtt
tctaagacccctaagaaaactcattcggatgccaaaaaaggacagaatagaagttcaaat
tacctcagttgtaggacaactcctgctatagtgccaccaaagaaatttcgtcagtgtcct
gaaccaacttcaacagtggagaaacttggcctgaaaaagggtcctcgtagggcatttgag
ttgtcccagcgatctttggattatgtagctcagttacgtgatcatggcaaaactgttgga
gtagttgatactcgaaaaaagactaaattaatttctcctcagaacctgtctgtcagaaat
aataagaaactgctgactagtcaagaacttcagatgcaaaggcagatcagacccaaatca
caaaaaaatagacaaagactttctgattgtgaaagtacagatacttcaggagcagggcct
catacagcacagaattctgacttacttgtaccagaatctgataggtcagattatgattgt
acaggaggaactgaggtacttgccaacagtaatgaaaaacagttaataaaatgcatgcct
tctgaaccagaaaccataaaagcaaaacatgggtctccagcgactgatggtgcttgccct
ttgaaccaatgtgattctatagtgttaaatggaacggtaccaacaagtgaagtaattgtt
tgtacttcagaggaccctctggggggaggtgatccgacagcacatcatacagagatggca
actttgaacgagggagagcctgactccagcagtgatatagaggaagagaacttgttttta
acacaaaatgatcctgaagatatggatttatgttcacaaatggagaatgacaattataaa
ttcattgaactaattcatggaaaagatacagttcaggttgaagaagattctgtaagtcag
cctcagttggaatctttgagtggcacaaagtgtaagtacaaagattgtcttgaaaccaca
aaaaaccagggtgaatactgcccacaacactctgaagtgaaagcagcagatgacgatgta
tttcgtaaacctggtttgcctccttctgcatctaaacctttgagacctaccactgctaag
atttttagctcaaagagtacttcacgaattgctggtctttctaaatctttggaaacttct
tcagcactttcaccatctctaaaaaataagtcaaaggggatacagtcaattttgaaagta
ccacagccagctcccctcgtagctcagaagccagtgggtgaaatgaaaaattcgagcaat
gttcttcatcctcagtctccgaataattccaacaggcaaggttgcaaagttccatttggt
gaaagcaaatattttccatcttcctctccagtaaacgttctcttgtcatcacagtctgtc
tctgacaccttcgttaaagaggtcttaaaatggaaatatgaaatgtttttgaactttgat
cagtgtgggccccctgcaagtctttgtcagtccatctcaagacctgtgcctgtcagattt
cacaattatggagattattttaatatttttttccctttggtggtattgaatacttttgaa
acagtggcgcaggaatggctcaactctccaaatagagagaatttctaccagttgcaagta
cgaaaatttcctgccgattatataaaatactgggagtttgcggtttatctggaagaatgt
gaattggctaaacagctttatccaaaggaaaacgatttggtgtttttagttcctgagaga
ataaatgaagagaagaaagatgcagagagaaatgacatacaagatctccacgaatatcat
tctggttatgttcataaatttcgccgcacttcagtcatgcgtaatgggaaagctgagtgt
tacctttccatccagactcaagagaattttccggccaatttaaacgaacttgtgaattgt
attgtaatcagttctctggtaacgacacaaaggaagttgaaagccatgtctctgttgggt
agtcggaaccaactggctagagctgttctgaatccaaaccctatggacttctgtacaaaa
gatttactaactacaacatctgagagaattattgcttacttaagagatttcaatgaagac
caaaagaaagcaatagaaactgcatatgctatggtgaaacactcaccatcagttgccaaa
atctgcttgattcatggaccacctggaacaggaaaatcaaaaactattgtcggcctcctc
tattgtctactgacagagaaccagaggaaggggcattcagacgaaaactccaatgccaaa
atcaaacaaaaccgtgtcctcgtgtgtgcaccttccaatgcagctgttgatgaactcatg
aaaaaaattatccttgaattcaaagaaaaatgtaaagacaagaagaatcctttaggaaac
tgtggagatataaatttagtacgactgggtccagaaaagtctattaataatgaggttcta
aagttcagtttggacagccaagtaaaccacagaatgaaaaaagatttaccttctcatgtt
caggcgatgcataaaagaaaggaatttctagattatcagttggatgagctttcccggcag
cgagctctatgccgaggtggacgggaaatacagaggcaagaattagatgaaaacatttcc
agagtttctaaggaaaggcaggaacttgcttctaaaattaaagaggttcaaggacgccca
cagaaaacacagagtatcatcatcttagagtcccatgtcatctgctgcacattgagcaca
agtggtggcttactacttgaatctgctttccgggggcaagggggtgtccccttcagctgt
gtcattgttgatgaggctggacagtcttgtgaaattgagacgcttaccccactcatccat
cgctgcaataagctcatcctagtaggagaccccaagcagctccctcccacagtcatctct
atgaaagcacaggagtatggctacgaccagtcaatgatggctcgcttctgcagactgctg
gaagagaatgtagaacacaacatgatcagcaggctgcctattctgcagctcactgtgcag
tacaggatgcatccagacatatgcctcttcccttctaattatatttacaacagaaactta
aaaacaaatagacagacagaaaccattcgatgttcatcagactggccatttcaaccatac
cttgtgtttgatgtcggagatggttcagaaagacgggataatgactcatacataaatgtt
caagaaataaaactggtgatggaaataattaagcttattaaagacaaaagaaaggatgtt
agttttcgaaacattggcataataactcattacaaggcccagaagacgatgattcagaag
gatttggacaaagagttcgatagaaaaggaccagcagaagtagatactgtggatgcgttc
cagggtcggcagaaggattgtgttattgttacatgtgtcagagcaaatagcgtgcaaggt
tcaattggattcctggcaagtttgcagagattgaatgtcaccatcacacgagccaagtac
agcctcttcatcctcggacatttgaggaccctgatgcaacttcttcctaggagcttttgt
gtacacgtgaaccattcgccttttttcagcccagaacccaagtatctacactgggctctc
aaggaaaaccagcattggaatcagctgattcaggatgctcagaagcgtggtgccattatt
aagacctgtgacaaaaactatagacatgatgcaatgaagattctgaaactcaagcccgtg
ctacagagaagtctcactcaccctcctaccatagccccagaggtatccagaccccagggt
ggcttgcccagcagcaagctagacagtggatttgccaaaacatcttttgctgcttctcta
taccacacaccctctgactccaaggaaactactcttactgttacttcaaaggaccctgaa
agacctcctgttcatgaccaacttcgggacccacgactgctgaagaggatgggcattgag
gtcaaaggaggaatattcctatgggatccacagccctcgagcccccagcatcctggagca
acacctcctgcaggagagccgagcttccctgtcgttcaccaggacctgggccatgtacag
cagcctgctgctgtagtggctgctctgagcagccacaaacctcccgtgcagggcgaacct
ccagctgccagtcccgaggcttccacgtgtcagagcaaatgtgatgacccagaagaggag
ctctgtcacaggagagaggccagggctttcagtgaaggcgagcaggagaagtgtggttcc
aagacccctcacaccaggaggaactctaggtgggacaagaggagaccggagcaggaggac
agcagttccaagaaaagaaagcttttatag
DBGET
integrated database retrieval system
