Theropithecus gelada (gelada): 112608270
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Entry
112608270 CDS
T08041
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge01521
EGFR tyrosine kinase inhibitor resistance
tge04062
Chemokine signaling pathway
tge04081
Hormone signaling
tge04148
Efferocytosis
tge04151
PI3K-Akt signaling pathway
tge04217
Necroptosis
tge04550
Signaling pathways regulating pluripotency of stem cells
tge04630
JAK-STAT signaling pathway
tge04658
Th1 and Th2 cell differentiation
tge04659
Th17 cell differentiation
tge04725
Cholinergic synapse
tge04917
Prolactin signaling pathway
tge04920
Adipocytokine signaling pathway
tge04933
AGE-RAGE signaling pathway in diabetic complications
tge04935
Growth hormone synthesis, secretion and action
tge05140
Leishmaniasis
tge05145
Toxoplasmosis
tge05152
Tuberculosis
tge05161
Hepatitis B
tge05164
Influenza A
tge05167
Kaposi sarcoma-associated herpesvirus infection
tge05168
Herpes simplex virus 1 infection
tge05200
Pathways in cancer
tge05207
Chemical carcinogenesis - receptor activation
tge05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
tge05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
112608270 (JAK2)
04151 PI3K-Akt signaling pathway
112608270 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
112608270 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
112608270 (JAK2)
09143 Cell growth and death
04217 Necroptosis
112608270 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
112608270 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
112608270 (JAK2)
04659 Th17 cell differentiation
112608270 (JAK2)
04062 Chemokine signaling pathway
112608270 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
112608270 (JAK2)
04917 Prolactin signaling pathway
112608270 (JAK2)
04935 Growth hormone synthesis, secretion and action
112608270 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
112608270 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
112608270 (JAK2)
05207 Chemical carcinogenesis - receptor activation
112608270 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
112608270 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
112608270 (JAK2)
05164 Influenza A
112608270 (JAK2)
05168 Herpes simplex virus 1 infection
112608270 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
112608270 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
112608270 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
112608270 (JAK2)
05140 Leishmaniasis
112608270 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
112608270 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
112608270 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
112608270 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tge01001
]
112608270 (JAK2)
Enzymes [BR:
tge01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
112608270 (JAK2)
Protein kinases [BR:
tge01001
]
Non-receptor tyrosine kinases
JAK family [OT]
112608270 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
SH2_1
Jak1_Phl
FERM_F1
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
112608270
NCBI-ProteinID:
XP_025215856
Ensembl:
ENSTGEG00000020951
LinkDB
All DBs
Position
15:complement(76722462..76824035)
Genome browser
AA seq
1049 aa
AA seq
DB search
MFALMSETERIWYPPNHVFHIDESTRHNVLYRIRFYFPRWYCSGSNRAYRHGISRGAEAP
LLDDFVMSYLFAQWRHDFVHGWIKVPVTHETQEECLGMAVLDMMRIAKENDQTPLAIYNS
ISYKTFLPKCIRAKIQDYHILTRKRIRYRFRRFIQQFSQCKATARNLKLKYLINLETLQS
AFYTEKFEVKEPGSGPSGEEIFATIIITGNGGIQWSRGKHKESETLTEQDLQLYCDFPNI
IDVSIKQANQEGSDESRVVTIHKQDGKNLEIELSSLREALSFVSLIDGYYRLTADAHHYL
CKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGLYVLRCSPKDFNKYFLTFAVER
ENVIEYKHCLITKNENEEYNLSGTKKNFSSLKDLLNCYQMETVRSDNIIFQFTKCCPPKP
KDKSNLLVFRTNGVSDVPTSPTLQRPTHMNQMVFHKIRNEDLIFNESLGQGTFTKIFKGI
RREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMSKLSHKHLVLNYGVCVCGEENI
LVQEFVKFGSLDTYLKKNKNCINILWKLEVAKQLAWAMHFLEENTLIHGNVCAKNILLIR
EEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPECIENPKNLNLATDKWSFGTTL
WEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWAELANLINNCMDYEPDFRPSFRAVIR
DLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSV
EMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRR
NLKLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQICKGMEYLGTKRYIHRDLATRNIL
VENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVV
LYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMT
ECWNNNVNLRPSFRDLALRVDQIRDNMAG
NT seq
3150 nt
NT seq
+upstream
nt +downstream
nt
atgtttgctttaatgagtgaaacagaaaggatctggtatccacccaaccatgtcttccat
atagatgagtcaaccaggcataatgtactctacagaataagattttactttcctcgttgg
tattgcagcggcagcaacagagcctatcggcatggaatatctcgaggtgctgaagctcct
cttcttgatgactttgtcatgtcttacctctttgctcagtggcggcatgattttgtgcat
ggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttgggatggcagtg
ttagatatgatgagaatagccaaagaaaatgatcaaaccccactggccatctataattct
atcagctacaagacattcttaccaaaatgtattcgagcaaagatccaagactatcatatt
ttgacaaggaagcgaataaggtacagatttcgcagatttattcagcagttcagccaatgc
aaagccactgccagaaacttgaaacttaagtatcttataaatctggaaaccctgcagtct
gccttctacacagagaaatttgaagtaaaagaacctggaagtggtccttcaggtgaggag
atttttgcaaccattataataactggaaacggtggaattcagtggtcaagagggaaacat
aaagaaagtgagacactgacagaacaggatttacagttatattgcgattttcctaatatt
attgatgtcagtattaagcaagcaaaccaagagggttcagatgaaagccgagttgtaact
atccataagcaagatggtaaaaatctggaaattgaacttagctcattaagggaagctttg
tctttcgtgtcattaattgatggatattatagattaactgcagatgcacatcattacctc
tgtaaagaagtagcgcctccaacagtgcttgaaaatatacaaagcaactgtcatggccca
atttcgatggattttgccattagtaaactgaagaaagcaggtaatcagactggactgtat
gtacttcgatgcagtcctaaggactttaataaatattttctgacttttgctgtcgagcga
gaaaatgtcattgaatataaacactgtttgattacaaaaaatgagaatgaagagtacaac
ctcagtgggacaaagaagaacttcagcagtcttaaagatcttttgaattgttaccagatg
gaaaccgttcgctcagacaatataattttccagtttactaagtgctgtcccccaaagcca
aaagataaatcaaaccttctagtcttcagaacgaatggtgtttctgatgtaccaacctca
ccaacattacagaggcctactcatatgaaccaaatggtgtttcacaaaatcagaaatgaa
gatttgatatttaatgaaagccttggtcaaggcacttttacaaagatttttaaaggcata
cgaagagaagtaggagactatggtcaacttcatgaaacagaagttcttttaaaagttctg
gataaagcacatagaaactattcagagtctttctttgaagcagcaagcatgatgagcaag
ctttctcacaagcatttggttttaaattatggagtatgtgtctgtggagaggagaatatt
ctggttcaggagtttgtaaaatttggatcactcgatacatacctgaaaaagaataaaaat
tgtataaatatattatggaaacttgaagttgcgaaacagttggcatgggccatgcatttt
ctagaagaaaacacccttattcatgggaatgtgtgcgccaaaaatattctacttatcaga
gaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcctggcattagt
attacagttttgccaaaggacattcttcaggagagaataccatgggtaccacctgaatgc
attgaaaatcctaaaaatttaaatttggcaacagacaaatggagttttggtaccactttg
tgggaaatctgcagtggaggagataaacctctaagtgccctggattctcaaagaaagctg
caattttatgaagataggcaccagcttcctgcaccaaagtgggcagaattagcaaacctt
ataaataattgtatggattatgaacccgatttcaggccttctttcagagccgtcatacga
gatcttaacagtttgtttactccagattatgaactattaacagaaaatgacatgttacca
aatatgaggataggtgccctagggttttctggtgcctttgaagacagggatcctacacag
tttgaagagagacatttgaaatttctacagcaactcggcaagggtaattttgggagtgtg
gagatgtgccggtatgaccctctacaggacaacactggggaggtggtggctgtaaaaaag
cttcagcatagtactgaagagcacctgagagactttgaaagggaaattgaaatcctgaaa
tccctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgctggtcggcgt
aatctaaaattaattatggaatatttaccatatggaagtttacgagactatcttcaaaaa
cataaagaacggatagatcacaaaaaacttctgcagtacacatctcagatatgcaagggt
atggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagaaatatattg
gtggagaatgagaacagagttaaaattggagattttgggttaaccaaagtcttgccacaa
gacaaagaatactataaagtaaaggaacctggtgaaagtcccatattctggtatgctcca
gaatcactgacagagagcaagttttctgtggcctcagatgtttggagctttggagtggtt
ctgtatgaacttttcacatacattgagaagagtaaaagtccaccagcggaatttatgcgt
atgattggcaatgataaacaaggacagatgatcgtgttccatttgatagaacttttgaag
aataatggaagattaccaagaccagatggatgcccagatgagatttatatgatcatgaca
gaatgctggaacaataatgtaaatctacgcccctcctttagagatctagctcttcgagtg
gatcaaataagggataacatggctggatga
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integrated database retrieval system
