KEGG   Theropithecus gelada (gelada): 112608327
Entry
112608327         CDS       T08041                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge04064  NF-kappa B signaling pathway
tge04072  Phospholipase D signaling pathway
tge04151  PI3K-Akt signaling pathway
tge04380  Osteoclast differentiation
tge04611  Platelet activation
tge04613  Neutrophil extracellular trap formation
tge04625  C-type lectin receptor signaling pathway
tge04650  Natural killer cell mediated cytotoxicity
tge04662  B cell receptor signaling pathway
tge04664  Fc epsilon RI signaling pathway
tge04666  Fc gamma R-mediated phagocytosis
tge05152  Tuberculosis
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05168  Herpes simplex virus 1 infection
tge05169  Epstein-Barr virus infection
tge05171  Coronavirus disease - COVID-19
tge05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    112608327 (SYK)
   04072 Phospholipase D signaling pathway
    112608327 (SYK)
   04151 PI3K-Akt signaling pathway
    112608327 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    112608327 (SYK)
   04613 Neutrophil extracellular trap formation
    112608327 (SYK)
   04625 C-type lectin receptor signaling pathway
    112608327 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    112608327 (SYK)
   04662 B cell receptor signaling pathway
    112608327 (SYK)
   04664 Fc epsilon RI signaling pathway
    112608327 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    112608327 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    112608327 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    112608327 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    112608327 (SYK)
   05168 Herpes simplex virus 1 infection
    112608327 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112608327 (SYK)
   05169 Epstein-Barr virus infection
    112608327 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    112608327 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tge01001]
    112608327 (SYK)
Enzymes [BR:tge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     112608327 (SYK)
Protein kinases [BR:tge01001]
 Non-receptor tyrosine kinases
  SYK family
   112608327 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 DUF7145 Kdo DUF7063 ABC1 RIO1
Other DBs
NCBI-GeneID: 112608327
NCBI-ProteinID: XP_025215936
Ensembl: ENSTGEG00000001853
UniProt: A0A8D2EAS5
LinkDB
Position
15:103874720..103969248
AA seq 635 aa
MASSGMADNANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRK
AHHYTIERELNGTYAIAGGRTHASPADLCHYHSQESDGLVCLLKKPFNRPQGVQPKTGPF
EDLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISREESEQ
IVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQL
VEHYSYKADGLLRVLTVPCQKIGTQGNVNFGGRPQLPGSHPATWSAGGIISRIKSYSFPK
PGHRKPSPAQGNRPESTVSFNPYEPEVAPWAAEKGPQREALPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPRE
MYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggcgagcagcggcatggctgacaacgccaaccacctgcccttctttttcggcaacatc
acccgggaggaggcagaagattacctggtccaggggggcatgagcgatgggctctatttg
ctgcgccagagccgcaactacctgggcggcttcgccctgtccgtggcgcacgggaggaag
gcacaccactacaccatcgagcgggagctgaacggcacctacgccatcgctggcggcagg
acccacgccagccccgccgacctctgccactaccactcgcaggagtctgatggcctggtc
tgcctcctgaagaagcccttcaaccggccccagggggtgcagcccaagactgggcccttt
gaggacttgaaggaaaacctcatcagggaatatgtgaagcagacatggaacctgcagggt
caggctctggagcaggccatcatcagccagaagcctcagctggagaagctgatcgccacc
acagcccatgaaaaaatgccttggttccatggaaaaatctctcgagaagagtctgagcaa
attgtcctgataggatcaaagacaaacggaaagttcctgatccgagccagagacaacaac
ggctcctacgccctgtgcctgctgcacgaagggaaggtgctgcactatcgcattgacaaa
gacaagacagggaagctctccatccccgagggaaagaagttcgacacgctctggcagctc
gtcgagcattattcttataaagcagatggtttgttaagagttcttactgtcccgtgtcaa
aaaatcggcacacagggaaatgttaattttggaggtcgtccgcaacttccaggttcccat
cctgcgacttggtcagcgggtggaataatctcaagaatcaaatcatactccttcccaaag
cctggccacagaaagccctcccctgcccaagggaaccggccagagagtactgtgtcattc
aatccgtatgagccagaagttgcaccctgggctgcagaaaaaggcccccagagagaagcc
ctacccatggacacagaggtgtatgagagcccctatgcggaccctgaggagatcaggccc
aaggaggtttacctggaccgaaagctgctaacgctggaagacaaagaactgggctctggt
aattttggaactgtgaaaaagggctactaccaaatgaaaaaagttgtgaaaacagtggct
gtgaaaattctgaaaaacgaggccaatgaccccgctcttaaagatgagttattagcagaa
gcaaatgtcatgcagcagctggacaacccgtacatcgtgcgtatgatcgggatatgcgag
gccgagtcctggatgctggttatggagatggcagaacttggtcccctcaataagtatttg
cagcagaacagacatgtcaaggataagaacatcatagaactggttcatcaggtttccatg
ggcatgaagtatctggaggagtgcaattttgtgcacagagatctggccgcaagaaatgtg
ttgctagttactcaacattatgccaagatcagtgatttcggactttccaaagcactgcgt
gctgatgaaaactactacaaggcccagacccatggaaagtggcctgtcaagtggtacgct
ccggaatgcatcaactactacaagttctccagcaaaagcgatgtctggagctttggagtg
ttgatgtgggaagcattctcctacgggcagaagccgtatcgagggatgaaaggaagtgaa
gtcaccgctatgttagaaaaaggagagcggatggggtgccctgcaggatgtccaagagag
atgtacgatctcatgaacctgtgctggacatacgatgtggagaacaggcccggattcgca
gcagtggaactgcggctgcgcaattactactatgacgtggtgaactaa

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