Theropithecus gelada (gelada): 112609197
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Entry
112609197 CDS
T08041
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
tge
Theropithecus gelada (gelada)
Pathway
tge00260
Glycine, serine and threonine metabolism
tge00630
Glyoxylate and dicarboxylate metabolism
tge00670
One carbon pool by folate
tge01100
Metabolic pathways
tge01200
Carbon metabolism
tge01230
Biosynthesis of amino acids
tge01240
Biosynthesis of cofactors
tge01523
Antifolate resistance
tge04981
Folate transport and metabolism
Module
tge_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
tge00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
112609197 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
112609197 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
112609197 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
112609197 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
112609197 (SHMT1)
Enzymes [BR:
tge01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
112609197 (SHMT1)
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GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
112609197
NCBI-ProteinID:
XP_025217493
Ensembl:
ENSTGEG00000003027
UniProt:
A0A8D2JV29
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All DBs
Position
16:74680536..74718973
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AA seq
483 aa
AA seq
DB search
METPVNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADENGAYLMADMAHISGLVVAGV
VPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALMELGYKIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQK
VAQFIHRGIELTLQIQSDVGVRATLKEFKERLAGDKYQGAVQALREEVESFASLFPLPGL
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NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atggagacgccggtcaatggggcccacaaggatgctgacctgtggtcctcacatgacaag
atgctggcacagcccctgaaagacagtgatgttgaggtttacaacatcattaagaaggag
agtaaccggcagcgggttggattggagctgattgcctcggagaatttcgccagccgagca
gttttggaggccctaggctcttgcttaaataacaaatactctgaggggtacccgggccag
agatactatggcgggactgagtttattgatgaactggagaccctctgtcagaagcgagcc
ctccaggcctataagctggacccacagtgctggggggtcaacgtccagccctactcaggc
tcccctgcaaacttcgctgtgtacactgccctggtggaaccccatgggcgcatcatgggc
ctggacctgccagatgggggccacctgacccatgggttcatgacagacaagaagaaaatc
tctgccacgtccatcttctttgaatctatgccttataaggtgaacccagacactggctac
atcaactatgaccagctggaggagaacgcacgcctcttccacccgaagttgatcatcgca
ggaaccagctgctactcccgaaacctggactatgcccggctgcggaagattgcagatgag
aatggggcgtatctcatggcggacatggcacacatcagcgggctggtggtggctggcgtg
gtgccctccccatttgaacactgccacgtggtgaccaccaccactcacaagaccctgcga
ggctgccgagctggcatgatcttctacaggaaaggagtgaaaagtgtggatcccaagact
ggcaaagagattctgtacaacctggagtctcttatcaattctgctgtgttccctggcctg
cagggaggtccccacaaccacgccattgctggggttgctgtggccctgaagcaagctatg
actctggaatttaaagtttatcagcaccaggtggtggccaactgcagggctctgtctgag
gcactgatggagctgggctacaaaatagtcacaggtggttctgataaccatttgatcctc
gtggatctccgttccaaaggcacagacggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacagaagtgctctgcggcccagtgga
ctgcggctggggaccccagcactgacgtctcgcggacttttggaaaaagacttccaaaaa
gtagcccagtttattcacagagggatagagctgaccctgcagatccagagcgacgttggt
gtcagagccaccctgaaggagttcaaggagagactggcaggggataagtaccagggggct
gtgcaggctctccgggaggaggttgagagcttcgcctctctcttccctctgcctggcctg
cctgacttctaa
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