KEGG   Theropithecus gelada (gelada): 112609481
Entry
112609481         CDS       T08041                                 
Symbol
MAP2K4
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4 isoform X1
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
tge  Theropithecus gelada (gelada)
Pathway
tge04010  MAPK signaling pathway
tge04012  ErbB signaling pathway
tge04620  Toll-like receptor signaling pathway
tge04664  Fc epsilon RI signaling pathway
tge04668  TNF signaling pathway
tge04912  GnRH signaling pathway
tge04926  Relaxin signaling pathway
tge04935  Growth hormone synthesis, secretion and action
tge04936  Alcoholic liver disease
tge05132  Salmonella infection
tge05135  Yersinia infection
tge05142  Chagas disease
tge05161  Hepatitis B
tge05166  Human T-cell leukemia virus 1 infection
tge05167  Kaposi sarcoma-associated herpesvirus infection
tge05169  Epstein-Barr virus infection
tge05208  Chemical carcinogenesis - reactive oxygen species
tge05417  Lipid and atherosclerosis
tge05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tge00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    112609481 (MAP2K4)
   04012 ErbB signaling pathway
    112609481 (MAP2K4)
   04668 TNF signaling pathway
    112609481 (MAP2K4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    112609481 (MAP2K4)
   04664 Fc epsilon RI signaling pathway
    112609481 (MAP2K4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    112609481 (MAP2K4)
   04926 Relaxin signaling pathway
    112609481 (MAP2K4)
   04935 Growth hormone synthesis, secretion and action
    112609481 (MAP2K4)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    112609481 (MAP2K4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    112609481 (MAP2K4)
   05161 Hepatitis B
    112609481 (MAP2K4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    112609481 (MAP2K4)
   05169 Epstein-Barr virus infection
    112609481 (MAP2K4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    112609481 (MAP2K4)
   05135 Yersinia infection
    112609481 (MAP2K4)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    112609481 (MAP2K4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    112609481 (MAP2K4)
   05418 Fluid shear stress and atherosclerosis
    112609481 (MAP2K4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    112609481 (MAP2K4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tge01001]
    112609481 (MAP2K4)
Enzymes [BR:tge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     112609481 (MAP2K4)
Protein kinases [BR:tge01001]
 Serine/threonine kinases: STE group
  STE7 family
   112609481 (MAP2K4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Seadorna_VP7 Pkinase_fungal ABC1 Haspin_kinase Choline_kinase APH
Other DBs
NCBI-GeneID: 112609481
NCBI-ProteinID: XP_025218073
Ensembl: ENSTGEG00000027886
UniProt: A0A8D2GGF5
LinkDB
Position
16:68350100..68471268
AA seq 410 aa
MAAPSPSGGGGSGGGSGSGTPGPVGSPAPGHPAVSSMQGFQINFCEKAQSKRKALKLNFA
NPPFKSTARFTLNPNPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIG
RGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALF
REGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRD
IKPSNILLDRSGNIKLCDFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSD
VWSLGITLYELATGRFPYPKWNSVFDQLTQVVKGDPPQLSNSEEREFSPSFINFVNLCLT
KDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQMPATPSSPMYVD
NT seq 1233 nt   +upstreamnt  +downstreamnt
atggcggctccgagcccgagcggcggcggcggctccgggggcggcagcggcagcggcacc
ccgggccccgtagggtccccggcgccgggccacccggccgtcagcagcatgcagggcttt
cagataaacttctgtgaaaaggcacaaagtaaacgcaaagcactgaagttgaattttgca
aatccacctttcaaatctacagcaaggtttactctgaatcccaatcctacaggagttcaa
aacccacacatagagagactgagaacacacagcattgagtcatcaggaaaactgaagatc
tcccctgaacaacactgggatttcactgcagaggacttgaaagaccttggagaaattgga
cgaggagcttatggttctgtcaacaaaatggtccacaaaccaagtgggcaaataatggca
gttaaaagaattcggtcaacggtggatgaaaaagaacaaaaacaacttcttatggatttg
gatgtagtaatgcggagcagtgattgcccatacatcgttcagttttatggtgcactcttc
agagagggtgactgttggatctgtatggaactcatgtctacctcgtttgataagttttac
aaatatgtatatagtgtattagatgatgttattccagaagaaattttaggcaaaatcact
ttagcaactgtgaaagcactaaaccacttaaaagaaaacttgaaaattattcacagagat
atcaaaccttccaatattcttctggacagaagtggaaatattaaactctgtgacttcggc
atcagtggacagcttgtggactctattgccaagacaagagatgctggctgtaggccatac
atggcacctgaaagaatagacccaagcgcatcacgacaaggatatgatgtccgctctgat
gtctggagtttggggatcacattgtatgagttggccacaggccgatttccttatccaaag
tggaatagtgtatttgatcaactaacacaagtcgtgaaaggagatcctccgcagctgagt
aattctgaggaaagggaattctccccaagcttcatcaactttgtcaacttgtgccttacg
aaggatgaatccaaaaggccaaagtataaagagcttctgaaacatccctttattttgatg
tatgaagaacgtgccgttgaggtcgcatgctatgtttgtaaaatcctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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